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1 CPP can be linked with various cargos like nanoparticles
2 CPP can enhance delivery of drugs to a targeted site whe
3 CPP FAP-310, a randomized, double-blind, Phase III trial
4 CPP have been effective for delivery of various chemothe
5 CPP sequence cyclisation or addition of a HA-sequence in
6 CPP-115 induced robust and significant increases in brai
7 CPP-115, a next-generation gamma-amino butyric acid (GAB
8 CPP-115-induced changes were exclusive to GABA and homoc
9 CPPs are known to be effective in promoting membrane tra
10 CPPs can also theoretically be used to modulate intracel
11 CPPs have tunable emission, possess large extinction coe
13 While the photophysical properties of BN-[10]CPP remains similar to its carbonaceous analogues, the e
14 ically, Ir-catalyzed hydrogenation of BN-[10]CPP selectively reduces the BN heterocyclic ring, which
19 tronic properties of two different [2]DBP[12]CPP nanohoops with electronically modifying substituents
21 Functionalized [12]cycloparaphenylenes ([12]CPPs) containing four alternating biphenyl and naphthyl
26 its of tetrahydro[6]cycloparaphenylene (4H[6]CPP) fused together through two 1,4-dimethoxybenzene uni
27 s as prototypical linear segments and [6]/[8]CPP as the radial segments, we demonstrate the formation
28 synthesis of two [8]cycloparaphenylenes ([8]CPP) derivatives, 1 and 2, bearing a monosubstituted ben
29 to synthesize a 2,2'-bipyridine-embedded [8]CPP, which we show can successfully coordinate to both P
30 planar chirality for the monosubstituted [8]CPP 1 and 2, whose configuration is here described by ap
32 fine-tuning of the binding properties of [8]CPP 1 toward pyridinium cations due to the presence of t
35 -embedded cycloparaphenylene nanohoop bipy[9]CPP to [Fe{H(2) B(pyz)(2) }] (pyz=pyrazolyl) produces th
39 ion of a 1,2-azaborine BN heterocycle into a CPP scaffold enables facile and selective late-stage fun
40 e and determine the secondary structure of a CPP within cells is critical for clarifying the mechanis
41 e, we report on transcellular transport of a CPP, designated the CL peptide, that increases the deliv
43 Treatment with systemic morphine abolished CPP to saphenous nerve block, demonstrating control of o
47 e-induced cross-sensitization of amphetamine CPP, DeltaFosB in the NAc and medial prefrontal cortex,
48 P10W, a peptide derived from the amphipathic CPP transportan 10; the second was based on DL1a, a synt
49 data suggest that cell uptake of amphipathic CPPs correlates with their adopted alpha-helix content i
51 cell type (10T1/2 > HepG2 > HeLa > HEK), and CPP sequence (Transportan > R8 > Penetratin~TAT > Xentry
52 ere exclusive to GABA and homocarnosine, and CPP-115 afforded brain GABA+ concentration changes compa
54 receiving injections of the NMDAr antagonist CPP immediately after four 45-min extinction sessions.
55 iginate from ionpair-pi interactions between CPP and activator implied that replacement of the pi-bas
62 Enhancement of LTP in the VTA and cocaine CPP in behaving rats both require glucocorticoid recepto
66 Cav1.2/CaMKII/S831 GluA1 pathway in cocaine CPP extinction, with data supporting contribution of hip
67 g in stress-induced reinstatement of cocaine CPP and provide insight into the impact of dose on the e
68 This stress-induced reinstatement of cocaine CPP depends on type 1 orexin receptors (OX1Rs), type 1 c
69 ing cells resulted in attenuation of cocaine CPP extinction and lack of extinction-dependent changes
73 a genetic deletion strategy and the cocaine CPP procedure to first define the contributions of alpha
75 and knockout mice alike all acquired cocaine-CPP and exhibited increased levels of silent synapses af
79 a time-kill assay revealed three conjugated CPPs rapidly kill Listeria within 20 minutes without dis
81 rtion and enables more accurate controlling, CPP-based efficient virus-free delivery strategy has bee
83 amolecular chemistries, cycloparaphenylenes (CPPs) have the potential to act as a new class of ligand
86 oriented pai-system of cycloparaphenylenes (CPPs) gives rise to photophysical properties unlike any
87 ass of compounds termed cycloparaphenylenes (CPPs)-shape-persistent macrocycles with built-in cavitie
90 ase (ODC) using low-dose eflornithine (DFMO, CPP-1X), combined with maximal PA export using low-dose
92 lar" monoterpenes chrysanthemyl diphosphate (CPP), lavandulyl diphosphate (LPP), and trace quantities
93 roduce the intermediate copalyl diphosphate (CPP), along with the more surprising finding of an atypi
94 e (LPP, TcCPS2) and (+)-copalyl diphosphate (CPP, TcCPS4), and three class-I diTPSs producing biforme
96 ween the evidence accumulation process (i.e. CPP) and subjective perceptual experience, suggesting th
98 e present a novel and bright orange-emitting CPP-based fluorophore showing a dramatic 105 nm red-shif
100 iana benthamiana identified SdCPS1 as an ent-CPP synthase, which is prevalent in roots and, together
101 s (diTPSs), the ent-copalyl diphosphate (ent-CPP) synthase SdCPS1, and the clerodienyl diphosphate (C
103 In this review, we summarize the existing CPP-based delivery system, emerging landscape of CPP app
104 l cargo to compare delivery capacity of five CPP sequences (Penetratin, R8, TAT, Transportan, Xentry)
105 we report a novel inactivation mechanism for CPP-115, a mechanism-based inactivator that undergoes GA
108 The computed (1)H NMR shifts of the guest CPP are shifted by about 1 ppm upfield relative to their
110 y inclined relative to the plane of the host CPP except when the host and guest differ by four phenyl
111 e structures of these partially hydrogenated CPPs were established by X-ray structure analysis, NMR s
112 optimal level to lower ICP without impairing CPP to counteract spaceflight-associated neuro-ocular sy
113 vasive method for lowering ICP and improving CPP for patients with pathologically elevated ICP on Ear
114 tion, and displayed no reward or aversion in CPP/CPA assays, suggesting that analogs might represent
116 ellular uptake of converting the residues in CPPs from l- to d-stereochemistry, but conflicting resul
118 rheumatoid arthritis (RA) exhibit increased CPP uptake and IL-1beta release in response to CaSR sign
127 solated from SCI rats showing TTA-P2-induced CPP (responders) was ~6 fold greater than the interspike
128 hese results suggest that pregabalin-induced CPP was successfully modulated by CEF which could serve
135 mized to: CPP-1X 750 mg and sulindac 150 mg, CPP-1X placebo and sulindac 150 mg, or CPP-1X 750 mg and
137 e we use dimeric fluorescence TAT as a model CPP to explore the broader consequences of l- to d-stere
138 oherent Raman microscopy to localize a model CPP-penetratin-and determine its secondary structure in
139 mice were trained using an unpaired morphine CPP design and was absent when morphine was administered
144 ally pai-conjugated cycloparaphenylenes ([ n]CPPs) of various ring sizes ( n = 5-12, where n is the n
148 e probed: previously reported hoop-shaped [n]CPPs and a novel family of all-phenylene figure-8 shaped
150 LA neurons was sufficient to induce nicotine CPP reinstatement, identifying an anatomically specific
151 the BLA prevented yohimbine-induced nicotine CPP reinstatement without affecting CPP acquisition.
153 g/kg, i.p.) induce reinstatement of nicotine CPP in a norbinaltorphimine (norBNI, a KOR antagonist)-s
160 When loaded with doxorubicin, irradiated NP-[CPP] significantly reduces neovascular lesion size.
162 er-induced CNV, intravenous injection of NP-[CPP] coupled to irradiation of the eye allows NP accumul
166 o receive either single daily 80 mg doses of CPP-115 (n=4) or placebo (n=2) for 6, 10, or 14 days.
169 if there was any difference in the impact of CPP in those with vs. those without a confirmed diagnosi
170 based delivery system, emerging landscape of CPP application in stem cell manipulation and reprogramm
175 onal materials has driven the development of CPPs as versatile platforms for applications including (
178 d information on the relative performance of CPPs in delivering proteins to cells, specifically the c
179 In our detailed investigation, two series of CPPs were probed: previously reported hoop-shaped [n]CPP
180 ess is known about the fate and structure of CPPs within cells largely due to measurement difficulty.
182 al class I (di)terpene synthase that acts on CPP to produce the abietane olefin miltiradiene, but als
184 this review is to highlight select works on CPPs, including basic structural design principles, vari
185 distinct TF families: one TCP (OsPCF2), one CPP (OsCPP5) and three NIN-like (OsNIN-like2, OsNIN-like
186 distinct TF families: one TCP (OsPCF2), one CPP (OsCPP5) and three NIN-like (OsNIN-like2, OsNIN-like
188 compound, Cs(7)(H(4)PO(4))(H(2)PO(4))(8), or CPP, which forms at elevated temperatures from the react
189 0 mg, CPP-1X placebo and sulindac 150 mg, or CPP-1X 750 mg and sulindac placebo once daily for 24 mon
192 4 potently stabilizes calciprotein particle (CPP) growth, consistently demonstrates low micromolar ac
194 The mean difference between the patients' CPP and their CPPopt was related to outcome for both cal
195 peptide containing cell-penetrating peptide (CPP) and collagen (COLL) domains is designed to undergo
196 e have developed a cell-penetrating peptide (CPP) conjugate of the HIV TAT protein that is fused to a
197 these approaches, cell penetrating peptide (CPP) is promising and affords widely used vector for eff
198 ridize it with the cell penetrating peptide (CPP) that allows for effective penetration of biological
199 ntified as a novel cell-penetrating peptide (CPP) that is able to efficiently internalize into human
200 rotamine (LMWP), a cell penetrating peptide (CPP), insulin showed greatly improved permeability throu
201 , enzyme-triggered cell penetrating peptide (CPP)-mediated systems seem to be a feasible approach.
205 oes into cells by cell-penetrating peptides (CPPs) and the bactericidal activity of antimicrobial pep
206 Although cationic cell-penetrating peptides (CPPs) are able to bind to cell membranes, thus promoting
210 antimicrobial and cell-penetrating peptides (CPPs) form amphipathic alpha-helices when bound to lipid
211 TDs), also called cell-penetrating peptides (CPPs), can promote uptake of macromolecules via endocyto
218 is conjugation to cell-penetrating peptides (CPPs); however, very little is known about the design of
220 , and normal CCS under the Clean Power Plan (CPP) and a hypothetical more stringent CO2 emission redu
221 ate that current-perpendicular-to-the-plane (CPP) junctions have three-orders-of-magnitude higher ele
223 f the broad-band centro-parietal positivity (CPP) and limb-selective beta-band (8-16 and 18-30 Hz) EE
224 G potential (the Centro-Parietal Positivity, CPP) to be a correlate of the accumulation of sensory ev
225 ce accumulation (centro-parietal positivity; CPP) show that predicted confidence affects neural prepa
226 that perfluorinated fatty acids are powerful CPP activators in HeLa cells but not in model membranes.
229 acute morphine-conditioned place preference (CPP) and stress-induced reinstatement of extinguished mo
230 ent of cocaine conditioned place preference (CPP) and the effects of low dose guanfacine on BNST acti
231 cues (ie, the conditioned place preference (CPP) apparatus) triggers a significant decrease in the n
234 on, of cocaine conditioned place preference (CPP) in male mice increased Cav1.2 L-type Ca(2+) channel
236 y, we used the conditioned place preference (CPP) model to investigate the involvement of the dopamin
238 bined with the conditioned place preference (CPP) paradigm to determine the relationship between the
244 Studies using conditioned place preference (CPP) tests of reward indicate that song production in gr
245 d that cocaine conditioned place preference (CPP) training followed by abstinence selectively potenti
255 he mathematical model predicted preferential CPP into cells with lower cell stiffness, expected from
256 determined the cerebral perfusion pressure (CPP) at which the pressure reactivity (PRx or wPRx) was
262 We hypothesize "cell-projection pumping" (CPP), in which cytoplasm in retracting cell projections
268 subsequent 90-min extinction retention test, CPP-treated rats lever pressed less than saline-treated
270 ght cleaves DEACM from the CPP, allowing the CPP to migrate from the NP core to the surface, renderin
273 ation with blue light cleaves DEACM from the CPP, allowing the CPP to migrate from the NP core to the
274 idence accumulation signal (reflected in the CPP amplitude) is mediated by the level of subjective ex
279 NA interference targeting either both of the CPP synthases, TwTPS7v2 and TwTPS9v2, or the subsequentl
280 spectra, giving access to information on the CPP/lipid interaction at a molecular level such as depth
282 Once accumulated at the targeting site, the CPP modified drug is released from the blockage by a sec
291 gible adults with FAP will be randomized to: CPP-1X 750 mg and sulindac 150 mg, CPP-1X placebo and su
293 g loaded applications, i.e. enzyme-triggered CPP-mediated systems in drug delivery were reviewed.
294 nt types of applications of enzyme-triggered CPP-mediated systems in tumor imaging were illustrated.
299 Our results suggested that conjugation with CPP followed by encapsulation in MNPs provides an effect