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2 bject, paired comparison of MDI and CSII and CSII with 12 months postislet transplantation in 10 type
3 within-subject, paired comparison of MDI and CSII and CSII with 12 months postislet transplantation i
6 s used randomized crossover design comparing CSII versus CLC during identical 22-h hospitalizations i
8 on glycemic control and hypoglycemia, except CSII has a favorable effect on glycemic control in adult
12 ), continuous subcutaneous insulin infusion (CSII) and islet transplantation to reduce hypoglycemia a
13 of continuous subcutaneous insulin infusion (CSII) before randomization to CSII plus troglitazone (n
14 Continuous subcutaneous insulin infusion (CSII) is an essential insulin replacement therapy in the
15 p (continuous subcutaneous insulin infusion [CSII]), known as artificial pancreas, can help optimize
16 y (continuous subcutaneous insulin infusion; CSII) in patients with type 1 diabetes using continuous
18 ssociated with the subcutaneous insertion of CSII catheters, which require replacement and rotation o
19 ic clamp 1) at baseline, 2) after 4 weeks of CSII, and 3) after CSII plus either troglitazone or metf
21 zation to CSII plus troglitazone (n = 10) or CSII plus metformin (n = 10); euglycemia was maintained
22 0.9; 3.3 mmol/mol [SD 9.8]) in the CGM plus CSII group and 0.1% (0.4; 1.1 mmol/mol [4.4]) in the CGM
23 36 (97%) of 37 participants in the CGM plus CSII group and 35 (92%) of 38 participants in the CGM pl
24 pants were randomly assigned to the CGM plus CSII group and 38 participants were randomly assigned to
25 s 6.7 days per week (SD 0.8) in the CGM plus CSII group and 6.9 days per week (0.3) in the CGM plus M
26 was 791 min per day (SD 157) in the CGM plus CSII group and 741 min per day (225) in the CGM plus MDI
30 ubcutaneous insulin infusion (insulin pumps [CSII]), and glucometers alongside insulin access represe
31 ring the tip end of commercial off-the-shelf CSII catheters fully resolves early skin irritations, ex
32 minipigs (from 2 to 13 days, under standard CSII-wearing conditions of insulin pump therapy and in a
37 ulin infusion (CSII) before randomization to CSII plus troglitazone (n = 10) or CSII plus metformin (
39 glycemia suitable for islet transplantation, CSII decreased hypoglycemia frequency and glycemic varia
40 reductions in all baseline parameters versus CSII, respectively, HbA1c (6.4% cf 8.2%), median HYPOsco
41 % with CSII plus troglitazone (P < 0.005 vs. CSII alone) and was then 45% higher than in the CSII plu
42 h CSII plus metformin, but improved 29% with CSII plus troglitazone (P < 0.005 vs. CSII alone) and wa
44 ecreased 53% with troglitazone compared with CSII alone (48+/-4 vs. 102+/-13 U/day, P < 0.001), but o
45 eved with CSII alone and was maintained with CSII plus an oral agent (mean 24-h glucose: troglitazone
46 s mellitus, HbA1c levels decreased more with CSII than with MDI, but 1 study heavily influenced these
47 change significantly with CSII alone or with CSII plus metformin, but improved 29% with CSII plus tro
48 ensitivity did not change significantly with CSII alone or with CSII plus metformin, but improved 29%
49 time hypoglycemic on CGM were unchanged with CSII, SD glucose and CONGA4 reduced significantly (P < 0