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1 nocarpus reesii, which is closely related to Coccidioides.
2 dy could enhance phagocytosis and killing of Coccidioides.
3 rable to severe morbidity and mortality from Coccidioides.
4 of Valley fever, given an area is endemic to Coccidioides.
5 um of diseases caused by the dimorphic fungi Coccidioides.
6 the internal transcribed spacer 2 region of Coccidioides.
12 oses (DMs) of the United States-Histoplasma, Coccidioides, and Blastomyces-commonly known as endemic
15 ected meningitis, in whom CSF was tested for Coccidioides antibodies and CAg, were retrospectively re
16 a, is usually diagnosed by detection of anti-Coccidioides antibodies in cerebrospinal fluid (CSF), an
20 was to assess the diagnostic utility of CSF Coccidioides antigen (CAg) detection for the diagnosis o
21 ective study, including all patients in whom Coccidioides antigen detection in serum was performed be
23 MHC binding prediction on known and unknown Coccidioides antigens and then empirically tested the pr
25 tle is known about when and where infectious Coccidioides arthroconidia are present within the ambien
26 d with this antigen and challenged with live Coccidioides arthroconidia showed a reduction in the fun
28 nsplant recipients who were seropositive for Coccidioides but discontinued prophylaxis (case patients
30 s also been shown to react with patient anti-Coccidioides complement-fixing (CF) antibody and is a va
33 temperature were positively associated with Coccidioides detection, while soil moisture was negative
35 irst high-density transcriptomic analyses of Coccidioides development, defining morphology-dependent
36 ty of 227 predicted transcription factors in Coccidioides displaying spherule-enriched expression.
38 idomycosis is caused by the dimorphic fungus Coccidioides, endemic to the southwestern United States.
39 for asymptomatic coccidioidomycosis within a Coccidioides-endemic area allowed for identifying and ma
40 disease risk, using case data as a proxy for Coccidioides endemicity is not ideal because case data s
45 ricella-zoster virus, enterovirus, Brucella, Coccidioides, Histoplasma, and mycobacteria, were negati
46 ne of the human respiratory fungal pathogen, Coccidioides immitis (Ci) was cloned, sequenced, chromos
48 (URA5) gene of the human pathogenic fungus, Coccidioides immitis (Ci), was cloned, sequenced, chromo
49 from the human respiratory fungal pathogen, Coccidioides immitis (Ci), was cloned, sequenced, chromo
51 principally with plants, the dimorphic fungi Coccidioides immitis and Coccidioides posadasii are prim
52 f the closely related human pathogenic fungi Coccidioides immitis and Coccidioides posadasii to more
53 s with those derived from the CiCHS1 gene of Coccidioides immitis and the AnCHSC gene of Aspergillus
54 n (coccidioidin) derived from mycelial-phase Coccidioides immitis and was reactive with human, canine
55 ious experiments have provided evidence that Coccidioides immitis antigen 2 (Ag2) is a major T-cell-r
56 n G2a (IgG2a), IgG2b, and IgG3 antibodies to Coccidioides immitis antigen; and the influx of CD4(+) a
61 e report the structure and expression of the Coccidioides immitis BGL2 gene which encodes a previousl
63 this immunoreactive enzyme, we constructed a Coccidioides immitis cDNA lambda ZAP expression library
65 test reagents from three different ACCUPROBE Coccidioides immitis culture identification test lots ha
66 e in autolysis of the parasitic cell wall of Coccidioides immitis during the asexual reproductive cyc
67 been isolated from the culture filtrates of Coccidioides immitis endosporulating spherules and from
69 xpressed the proline-rich antigen (PRA) from Coccidioides immitis in Escherichia coli and evaluated i
70 infection, B6 mice had nearly 100-fold more Coccidioides immitis in their lungs than did B10 mice (l
71 there is also a difference in resistance to Coccidioides immitis infection among inbred mouse strain
72 2 decades to determine the seroincidence of Coccidioides immitis infections among U.S. military memb
76 Multinucleate parasitic cells (spherules) of Coccidioides immitis isolates produce a membranous outer
77 2 (Ag2), a major immunoreactive component of Coccidioides immitis mycelium- and spherule-phase cell w
78 n which several unusual morphologic forms of Coccidioides immitis occurred in biopsy tissue from the
79 We identified 5 patients with disseminated Coccidioides immitis or Histoplasma capsulatum with hete
81 n between IL-10 levels and susceptibility to Coccidioides immitis peritonitis in C57BL/6 (B6), DBA/2,
82 lusters (BGCs) from diverse fungi, including Coccidioides immitis RS, the causative agent of valley f
84 h either recombinant expression protein of a Coccidioides immitis spherule-derived proline-rich antig
85 yme, Champase, from the Valley fever fungus, Coccidioides immitis strain RS, was found to stereoselec
86 s, we used a temperature-sensitive mutant of Coccidioides immitis to immunize mice lacking subsets of
87 microsatellite loci from the human pathogen Coccidioides immitis to show that genetic diversity in t
88 oline-rich coccidioidal antigen (Ag2/PRA) of Coccidioides immitis were analyzed by comparison as vacc
89 Antibodies against a 33-kDa antigen from Coccidioides immitis were detected by ELISA in patients'
91 emic of coccidioidomycosis (etiologic agent, Coccidioides immitis) occurred between 1991 and 1994 in
93 in protection against primary infection with Coccidioides immitis, a dimorphic fungal pathogen that c
95 onstrate persistent colonization of soils by Coccidioides immitis, an agent of valley fever, in Washi
96 We have taken this approach in a study of Coccidioides immitis, an ascomycete fungus responsible f
98 h antigen (PRA), which protects mice against Coccidioides immitis, has been analyzed for differential
99 plasma capsulatum, Blastomyces dermatitidis, Coccidioides immitis, Paracoccidioides brasiliensis, Pen
100 le, water-soluble extract from cell walls of Coccidioides immitis, protects mice against lethal chall
101 civilians who reside or train in areas where Coccidioides immitis, the causative agent, is endemic.
103 sent in the cell wall of the fungal pathogen Coccidioides immitis, was investigated in a murine model
115 the isolated fungus (Histoplasma capsulatum, Coccidioides immitis/posadasii, Fusarium oxysporum, Aspe
120 plasma levels of NikZ that nearly eradicate Coccidioides in mice are achievable in patients and prov
121 rly understood due to irregular detection of Coccidioides in soil, disease underdiagnosis, and lack o
122 ions among children with JIA were 3 cases of Coccidioides (incidence rate 21 per 100,000 person-years
123 of T cells, B cells, and neutrophils to the Coccidioides-infected hypodermis com pared to wild-type
124 showed decreased acquisition of Th cells in Coccidioides-infected lungs compared with vaccinated wil
125 17A-producing CD4(+) T cells in the lungs of Coccidioides-infected mice correlated with better fungal
126 T-cell immunity in nonvaccinated mice during Coccidioides infection but does not impede the developme
127 gnal pathways are required for resistance to Coccidioides infection following subcutaneous challenge
128 tion in tissue or serology, but knowledge of Coccidioides infection imaging findings becomes importan
129 ansplant recipient likely reactivated latent Coccidioides infection in the donor lungs, leading to po
130 f the early events of protective immunity to Coccidioides infection in vaccinated mice contributes to
131 ne stimulates a robust Th17 immunity against Coccidioides infection through activation of the CARD9-a
132 We previously reported a vaccine against Coccidioides infection which contained three recombinant
139 ononuclear cells from patients with clinical Coccidioides infections and from endemic or nonendemic h
141 s, and it is believed the endemic region for Coccidioides is expanding in response to climate change.
144 ique by inferring the source populations for Coccidioides isolates recovered from patients treated ou
145 th their dead animal hosts in soil, and that Coccidioides metabolism genes, membrane-related proteins
147 IV-infected patient with a history of recent Coccidioides pneumonia but with negative Coccidioides se
151 the dimorphic fungi Coccidioides immitis and Coccidioides posadasii are primary pathogens of immunoco
153 we describe the identification of endogenous Coccidioides posadasii contamination in commercial rhesu
154 us Hypothesizing that the homologous gene in Coccidioides posadasii could be important for virulence,
157 y of recombinant T-cell-reactive proteins of Coccidioides posadasii in a murine model of coccidioidom
162 ugh the amino acid sequence of the urease of Coccidioides posadasii lacks a predicted signal peptide,
165 an pathogenic fungi Coccidioides immitis and Coccidioides posadasii to more clearly elucidate populat
166 from the heat shock protein gene (HSP60) of Coccidioides posadasii was used to control the transcrip
167 genic preparation derived from spherules (of Coccidioides posadasii), activate peripheral blood monon
168 nsible for such infections in North America (Coccidioides posadasii, Histoplasma capsulatum, and Blas
169 vaccinated with a live, attenuated mutant of Coccidioides posadasii, referred to as the DeltaT vaccin
170 both CD8(+) and CD4(+) T cells recruited to Coccidioides posadasii-infected lungs of nonvaccinated a
173 c infections, including an increased rate of Coccidioides, Salmonella, and herpes zoster compared to
174 43 patients (46.5%) compared with all other Coccidioides serologic results (13/111 [11.7%], P < 0.00
175 ent Coccidioides pneumonia but with negative Coccidioides serology determined by enzyme immunoassay a
176 ticles and then challenged intranasally with Coccidioides showed early lung infiltration of activated
178 patients treated outside the endemic area of Coccidioides sp., the etiological agents of human coccid
181 sitivity in persons with past infection with Coccidioides species is again available for clinical use
182 tin synthase inhibitor with activity against Coccidioides species that is being developed as a first-
183 in a community hospital setting to identify Coccidioides species using the new Becton Dickinson mole
185 internalizing, and presenting antigens from Coccidioides spherules and suggest that DC may play a cr
186 The endemic fungi Histoplasma capsulatum, Coccidioides spp, Blastomyces dermatitidis, and Paracocc
187 urs when animals and humans inhale spores of Coccidioides spp, soil-dwelling fungi of the southwester
192 pp. (n = 9), Paracoccidioides spp. (n = 10), Coccidioides spp. (n = 9), Histoplasma spp. (n = 7) and
198 s to develop a real-time PCR assay to detect Coccidioides spp. directly from clinical specimens.
199 s been reported to harbor parasitic cells of Coccidioides spp. in collective cases of the disseminate
202 owth in the saprobic and parasitic phases of Coccidioides spp. is partly responsible for production o
204 ly sensitive and specific means of detecting Coccidioides spp., growth in culture may take up to 3 we
205 g an RT-PCR method on the BD Max to identify Coccidioides spp., with sensitivity equivalent to cultur
206 munogenic properties in humans infected with Coccidioides that can be used to distinguish infected in
207 les genomes revealed evolutionary changes in Coccidioides that may underlie its infectious phenotype,
208 eses about the life history and evolution of Coccidioides, the genomes of several Onygenales, includi
211 ant system show promise for development of a Coccidioides vaccine, but further testing is needed to f
213 Exserohilum, Cryptococcus, Histoplasma, and Coccidioides, were studied, although most were case repo
214 s an airborne infection caused by the fungus Coccidioides, which is endemic to the southwestern Unite
215 ilar outcomes after pulmonary infection with Coccidioides, while vaccinated IL-1r1(-/-) mice revealed