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1 egulation of Abl and bRaf kinases as well as Cre recombinase.
2 Mice were given tamoxifen to induce Cre recombinase.
3 optical voltage sensor under the control of Cre recombinase.
4 targeted to the early DCT using a DCT-driven Cre recombinase.
5 tantly, can be conditionally expressed using Cre recombinase.
6 ibiotic resistance genes or enzymes, such as Cre recombinase.
7 disrupted in 2 different strains of mice via cre recombinase.
8 se line with sebocyte-specific expression of Cre recombinase.
9 essing (VIP+) GABAergic interneurons express Cre recombinase.
10 modelled by confined injection of adenoviral Cre recombinase.
11 e restored to wild type by gene editing with Cre recombinase.
12 27-bp cten promoter drives the expression of Cre recombinase.
13 h cell or tissue type-specific expression of Cre recombinase.
14 etween intrinsic flexibility and function in Cre recombinase.
15 which Notch activation is induced in HSCs by Cre recombinase.
16 flwt-Smn) can be conditionally deleted using Cre recombinase.
17 gain-of-function mutation is dependent upon Cre recombinase.
18 tein gene requires the presence of exogenous Cre recombinase.
19 assay using a reporter that is activated by Cre recombinase.
20 ate light-and-chemical regulated versions of Cre recombinase.
21 ression are activated only after exposure to Cre recombinase.
22 ) mice transduced with adenovirus expressing Cre recombinase.
23 atty acid binding protein 4) promoter-driven Cre-recombinase.
24 knockout mice with expression of Mx1 or Vav Cre-recombinase.
25 the DNA specificities of orthologous Dre and Cre recombinases.
27 tion of an adeno-associated virus expressing Cre recombinase (AAV-Cre) into the midbrain/pons of mice
29 ter fragment or by targeted integration of a Cre recombinase-activatable expression cassette driven b
30 isynaptic circuit, we constructed a panel of Cre recombinase-activated pseudorabies viruses (PRVs) th
31 ion of these lineages was only observed with Cre recombinase activation during early lung development
35 approach also mediated efficient delivery of Cre recombinase and Cas9:sgRNA complexes into the mouse
36 ommits suicide inside host cells by inducing Cre recombinase and deleting essential genes flanked by
37 ated viral vectors containing genes encoding Cre recombinase and green fluorescent protein were micro
38 synthetic sequence through the action of the Cre recombinase and no competition from homologous recom
39 xamine the role of PDGFR-alpha in HSCs, Lrat-Cre recombinase and Pdgfra-floxed mice were bred to gene
40 adeno-associated virus [AAV]) that expresses Cre recombinase and sgRNAs targeting Rb1, Tp53, and Rbl2
41 one oncogene (KRAS), achieved by delivering Cre recombinase and sgRNAs, which caused rapid lung tumo
43 hod RecWay assembly, as it makes use of both Cre recombinase and the commercially available Gateway c
44 ns of two unrelated genome editing proteins, Cre recombinase and zinc-finger nucleases, under conditi
45 t (KO) mouse lines, with viral expression of Cre-recombinase and a light-activated ion channel for op
47 ockdown, GRK2 gene deletion (GRK2(flox/flox)/cre recombinase) and overexpression of GRK2 and its regu
49 c markers (Sox2 and T) and tamoxifen-induced Cre recombinase-based lineage tracing to locate putative
52 pha) mouse line and a gene construct driving Cre recombinase (Cre) expression in NSP cells, led to in
53 mouse strains have been developed, in which Cre recombinase (Cre) expression is driven by an RPE-spe
56 Here, we generated knock-in mice expressing Cre recombinase (Cre) under the control of the endogenou
57 in the lung by nasal delivery of adenoviral Cre recombinase (Cre), here we show that KRAS(G12D) expr
60 m by injecting an adenoviral vector encoding Cre recombinase (Cre)-regulated farnesylated green fluor
61 ogeny of mice expressing tamoxifen-inducible Cre recombinase (Cre-ERT2) under the Aicda promoter cros
62 breeding these mice with lines that express Cre-recombinase (Cre) in early embryogenesis (EIIa-Cre)
63 pulse-labeled using the tamoxifen-dependent Cre recombinase, CreER(T2), expressed from the endogenou
66 describe a technique based on a destabilized Cre recombinase (DD-Cre) whose activity is controlled by
67 (+) .Foxo1 (L/L) mice with lineage-specific Cre recombinase deletion of floxed FOXO1 and compared th
68 human insulin receptoropathy in mice, using Cre recombinase delivered by adeno-associated virus to k
69 hod that exploits GFP for gene manipulation, Cre recombinase dependent on GFP (CRE-DOG), a split comp
71 onal band of Broca cholinergic neurons using Cre recombinase-dependent adeno-associated virally media
74 ng of SOM-expressing neurons in s. oriens, a Cre recombinase-dependent construct for channelrhodopsin
76 s nicotine reward behaviors, we engineered a Cre recombinase-dependent gene expression system to sele
77 ermine MN-enriched miRNA expression, we used Cre recombinase-dependent miRNA tagging and affinity pur
79 le gene deletion system based on a dimerised Cre recombinase (diCre) to target CRK3 and elucidate its
80 PR/Cas9 to facilitate use of the dimerisable Cre-recombinase (DiCre) that is frequently used to media
82 ingly, cells targeted by tamoxifen-inducible cre recombinase driven by nestin enhancer (Nes-creER) in
83 ngineered mouse model in which expression of Cre recombinase driven by the C-type lectin domain famil
84 constitutive activation of betacatenin using cre recombinase driven by the DEAD (Asp-Glu-Ala-Asp) box
85 ating alpha7nAChR(flox) with mice expressing Cre recombinase driven by the glial acidic fibrillary pr
86 generated the Mchr1-cre mouse that expresses cre recombinase driven by the MCHR1 promoter and crossed
87 s mouse strain to transgenic mice expressing Cre recombinase driven by the megakaryocyte (MK)-specifi
89 gene was deleted using a tamoxifen-inducible Cre recombinase driven by the ubiquitously expressed ROS
92 HIF-1alpha floxed mice with mice expressing Cre-recombinase driven by the calcium/calmodulin-depende
95 diated by KOR on DA terminals, we utilized a Cre recombinase-driven mouse line lacking KOR in DA neur
99 used two different mature RPE cell-specific Cre recombinase drivers to inactivate either Dicer1 or D
100 oral activation by tamoxifen (TAM)-inducible Cre recombinase Ela-CreERT in the submandibular gland (S
101 deno-associated virus-mediated expression of cre recombinase, eliminated cocaine-induced ERK phosphor
104 olerant mice; and (3) Tag-activation through Cre recombinase-encoding viruses in the liver and HCC de
107 pocytes prior to cold exposure, using Pdgfra-Cre recombinase estrogen receptor T2 fusion protein (Cre
108 ysis because they expressed a high amount of Cre recombinase exclusively in ameloblasts and showed de
109 expressing a tamoxifen-inducible variant of Cre recombinase expressed under control of the Npr2-prom
110 ory neurons of the postnatal forebrain using Cre recombinase expressed under the control of the alpha
111 ed mouse, and then crossed this mouse with a Cre recombinase expressing mouse driven by the human gli
112 ar Anchored Independent Labeling, to isolate Cre recombinase-expressing (Cre(+)) nuclei from the adul
113 oblasts with 2 different tamoxifen-inducible Cre recombinase-expressing gene-targeted mouse lines.
115 allowed the identification of synapses from Cre recombinase-expressing or GAL4-expressing neurons in
116 neurons chemogenetically using a retrograde Cre-recombinase-expressing canine adenovirus-2 in combin
117 lidation of a transgenic mouse line in which Cre recombinase expression has been targeted to cells ex
118 ion of floxed KOR or floxed p38alpha MAPK by Cre recombinase expression in dopaminergic neurons block
120 rter VGLUT2 may be exploited to drive robust Cre recombinase expression in RGCs without any expressio
121 system largely depends on the specificity of Cre recombinase expression in targeted stem or progenito
123 erate new rat strains (Cre drivers) in which Cre recombinase expression is carefully controlled tempo
124 ducible membrane-bound reporter and targeted Cre recombinase expression to a subset of glial progenit
125 bone osteocytes, no differences in Mbtps1 or cre recombinase expression were observed in cKO SOL, exp
130 hat were crossed with DAT-Cre mice, in which Cre- recombinase expression is under dopamine transporte
134 regions, we used transgenic mice expressing Cre recombinase from the Nkx2.1 promoter to ablate loxP-
137 rgeted deletion of gata3 driven by otoferlin-cre recombinase (gata3(fl/fl) otof-cre(+/-) ) in IHCs do
138 stem to excise the selectable marker and the cre recombinase genes from transgenic banana cv. 'Grande
139 enic lines expressing a controllable form of Cre recombinase have become valuable tools for manipulat
141 l La allele and used it in mice that express Cre recombinase in either B cell progenitors or the fore
142 system, in conjunction with mice expressing Cre recombinase in either parvalbumin-positive, somatost
143 Male and female transgenic mice expressing Cre recombinase in FSIs allowed us to identify these spa
145 validated a transgenic mouse line expressing cre recombinase in histidine decarboxylase-expressing ne
146 is used to specifically and inducibly drive Cre recombinase in ICC as a strategy to study GIST patho
148 fluorescent protein following activation by Cre recombinase in mice that express Cre recombinase in
151 o-associated viral (AAV) vector carrying the Cre recombinase in the hippocampus of mTORf/f mice recap
152 enomatous polyposis coli) upon expression of CRE recombinase in the liver and monitored their effects
153 ntly translated into full-length, functional Cre recombinase in the presence of nonsense suppressors
156 ggered by intravenous adenoviral delivery of Cre recombinase in transgenic mice expressing the hepato
158 line was assessed on interneurons expressing Cre recombinase in vasoactive intestinal peptide (VIP) o
159 ediated delivery of functional pDNA encoding Cre recombinase in vivo to tissues in transgenic Cre-lox
160 , once the tumor is induced by activation of Cre-recombinase in a tissue-specific manner, further gen
161 ocalized infusions of adeno-associated virus Cre-recombinase in adult, targeted knock-in mice with lo
162 glutamic acid decarboxylase (GAD67-GFP), or Cre-recombinase in cells that contain glutamic acid deca
165 roligins by stereotactic viral expression of Cre-recombinase in hippocampal CA1 region pyramidal neur
167 tamoxifen-inducible collagen type 2a1-driven Cre recombinase increased proliferation and beta-catenin
168 development of a transgenic mouse line where Cre-recombinase-induced expression of a mutant methionyl
172 t two-hybrid method, CrY2H-seq, which uses a Cre recombinase interaction reporter to intracellularly
174 oinflammation in the DR by viral delivery of Cre recombinase into interleukin (IL)-1beta(XAT) transge
175 rom lentiviral delivery of shRNAs along with Cre recombinase into lungs of Loxp-stop-Loxp-KRas mice.
176 letion of Pbx1 by retroviral transduction of Cre recombinase into Pbx2-deficient SVZ stem and progeni
177 1 or MAGL via injection of virally-delivered Cre recombinase into the MSDB of Cnr1(loxP/loxP) or Mgll
179 transgenic Cre line, in which expression of Cre recombinase is controlled by a previously identified
181 ne targeting using the bacteriophage-derived Cre recombinase is widely applied for functional gene st
187 tes in a cultured pre-B cell line as well as Cre recombinase-mediated Bcl11a(lox/lox) deletion in exp
191 events in preclinical mouse models requires Cre recombinase-mediated conditional gene expression in
192 n of Panx1 (Panx1 (-/-) Apoe (-/-) ) or with Cre recombinase-mediated deletion of Panx1 in endothelia
196 ducible lineage tracing to fate map, through Cre recombinase-mediated fluorescent reporter gene activ
199 Previous studies have demonstrated that Cre recombinase-mediated recombination can lead to combi
200 ic recombination system based on dimerizable Cre recombinase-mediated recombination in the apicomplex
201 nger needed after integration was excised by Cre recombinase-mediated recombination of lox sites.
202 eage tracings using cyclization recombinase (Cre) recombinase-mediated cell labeling represent the go
203 ion of Steroidogenic Factor-1 (SF1) to drive Cre-recombinase-mediated deletion of the brain muscle ar
205 centrosome amplification can be induced by a Cre-recombinase-mediated increase in expression of Polo-
209 h various neurone selective, promoter-driven Cre recombinase mice resulted in GCaMP3 expression in de
213 ty in mice and develop a new tissue specific Cre recombinase mouse model, we have established pCTEN-C
217 anterograde tracing using mice that express Cre recombinase only in neurons producing acetylcholine,
219 d nanoparticles with negatively supercharged Cre recombinase or anionic Cas9:single-guide (sg)RNA com
220 We characterize a previously developed split Cre recombinase (PA-Cre2.0) that is reconstituted upon l
222 s of Pam (0-Cre-cKO/cKO) atrial myocytes (no Cre recombinase, PAM floxed) were transduced with Cre-GF
224 nanoparticles (MSNs) as carriers to deliver Cre recombinase protein into maize (Zea mays) cells.
225 ify mutations in the dimerization surface of Cre recombinase (R32V, R32M and 303GVSdup) that improve
226 tegrase system in place of the bidirectional Cre recombinase reaction; and (iii) gel extraction by DN
227 o achieve constitutive HH signaling) using a Cre recombinase regulated by the lysozyme M promoter.
228 These mice were crossed with mice expressing Cre recombinase, regulated by the villin or CD11c promot
229 in postnatal testis, and a dual fluorescent Cre recombinase reporter to label FLC and ALC in vivo.
231 d disruptive sequence that can be deleted by Cre recombinase, resulting in restored IL-1R1 gene expre
232 trogradely transported AAV vector expressing Cre recombinase (Retro-Cre-GFP) into the BLA (Experiment
233 developed a recombinant JHMV that expresses Cre recombinase (rJ-Cre) and infected mice that universa
234 cells using smooth muscle protein 22-driven Cre recombinase (SMGRKO mice) and compared them with mic
239 essing tenocytes using a tamoxifen-inducible Cre-recombinase system and caused tendon growth in adult
240 combined with a split-intein-mediated split-Cre-recombinase system in mice to isolate, characterize,
241 the potent delivery of nM concentrations of Cre recombinase, TALE- and Cas9-based transcription acti
242 mary sarcomas generated with CRISPR-Cas9 and Cre recombinase technology had similar histology, growth
243 in the current study we used CRISPR/Cas9 and Cre recombinase technology to produce mice that lack GH
244 1(CreER) mice expressing tamoxifen-inducible Cre recombinase that allow for specific manipulation of
245 nic mouse under the control of both Flp- and Cre-recombinases that is an effective tool for circuit m
247 ce were crossed with mice transgenic for Pf4-Cre-recombinase (thrombopoietic deletion) or Cd11b-Cre-r
248 cinar cell-specific expression of knocked-in Cre recombinase through control of aquaporin 5 (Aqp5) pr
249 tability was mimicked with viral delivery of Cre recombinase to astrocytes in the LHA and rescued by
250 mbens with adeno-associated virus expressing Cre recombinase to create focal, homozygous Hdac3 deleti
251 lpha subunit and cell-specific expression of Cre recombinase to deplete PV(+) or SST(+) interneurons
253 lineage analysis has been accomplished using Cre recombinase to indelibly label a defined progenitor
254 l recombinase technology using both FlpO and Cre recombinases to generate primary sarcomas in mice wi
255 kout mouse model using progesterone receptor-Cre-recombinase to achieve Pten and Grp78 (cPten(f/f)Grp
256 We used Cre driver lines (mice expressing Cre recombinase) to comprehensively and selectively labe
257 ice with selective expression of tdTomato or cre recombinase together with optogenetics to investigat
258 ice with a retinoid acid receptor 2 promoter-Cre recombinase transgene (Rarb-cre) expressed in embryo
259 ock-out mice carrying an aP2 promoter-driven Cre recombinase transgene showed a blunted response to t
260 KD1 gene and heterozygous for an aquaporin-2-Cre recombinase transgene to achieve collecting duct-spe
264 kout (floxed) Ptpn11 allele (Ptpn11(fl)) and Cre recombinase transgenic mice to delete Ptpn11 specifi
268 artifacts associated with beta-cell-specific Cre-recombinase transgenic models, raising questions abo
270 hemiparkinsonian transgenic mice expressing Cre recombinase under control of the choline acetyltrans
271 IF-1alpha floxed mice with mice that express Cre recombinase under control of the glial fibrillary ac
272 U.1) was conditionally deleted in B cells by Cre recombinase under control of the Mb1 gene in Spib (e
273 erated mice that express tamoxifen-inducible Cre recombinase under control of the Plp1 promoter and c
274 ite cells in mice, using tamoxifen-inducible Cre recombinase under control of the satellite cell-spec
275 using mice expressing a tamoxifen-dependent Cre recombinase under the control of a fibroblast-specif
276 neered the expression of tamoxifen-inducible Cre recombinase under the control of a kidney-specific p
277 yn(flox/flox) animals with mice carrying the Cre recombinase under the control of the Cd79a promoter,
278 mice with CX3CR1(CreER) mice, which express Cre recombinase under the control of the CX3C chemokine
279 mice crossed with transgenic mice expressing Cre recombinase under the control of the mouse platelet
280 virus vectors and transgenic mice expressing Cre recombinase under the D1 promoter, we also found tha
281 manipulated in knock-in mice expressing the Cre recombinase under the endogenous parvalbumin promote
282 he circadian clock gene Bmal1 and expressing Cre recombinase under the endogenous Renin promoter (Bma
284 leles floxed at exon 1 to animals expressing Cre recombinase under the pre-proglucagon promoter.
286 allele using transgenic mice that expressed Cre-recombinase under control of the ubiquitous CAG prom
290 ection of a BAAV vector encoding a bacterial Cre recombinase via canalostomy in adult mice with floxe
291 IL-22-expressing cells, a sequence encoding Cre recombinase was cloned into the Il22 locus, and IL22
292 delity lineage tracing after confirming that Cre recombinase was mesothelial specific and faithfully
294 ssibility that the bovine K5 promoter-driven Cre-recombinase was active early in trophoblast-lineage
295 tor cells with adenovirus expressing GFP and Cre-recombinase was successful in GRP78 ablation, and th
296 us from cells, Tre, an engineered version of Cre recombinase, was designed to target a 34-bp sequence
297 rade tropism, a canine adenovirus expressing Cre recombinase, was injected into the left intermediola
299 tionally deleted using progesterone receptor Cre recombinase, which is expressed in both epithelial a
300 ing fluorescent parasite strains that inject Cre recombinase with their rhoptry proteins (Toxoplasma-