ライフサイエンスコーパス: DAI

1 DAI also interacts with RIP3 and this interaction potent

2 DAI at different brain regions was evaluated by neuropat

3 DAI binds to and colocalizes with endogenous RIP1 at cha

4 DAI causes immediate, sporadic axon damage followed by p

5 DAI has applications in the detection and identification

6 DAI is a novel application of biotin/streptavidin affini

7 DAI offers a new means of molecular profiling and monito

8 DAI score was calculated based on dietary data obtained

9 DAI was higher in Mdr1a (-/-) mice than in FVB mice, but

10 DAI-deficient mice fail to control IAV replication and s

11 ignificant upregulation of TLR-9 (P <0.006), DAI (P <0.001), and TLR-8 (P <0.01) in CP tissues compar

12 regulatory factors/Z-DNA binding protein 1 (DAI/ZBP1) bound plasmid DNA in the cytosol within 15 min

13 vage (BAL) eosinophilia observed at 7 and 14 DAI.

14 , 3-day and 6-day after imbibition (6-HAI, 3-DAI, and 6-DAI) were performed to characterize the regul

15 From 6-HAI to 3-DAI, rapid changes in transcript level occurred, includi

16 both control and ischemic animals, but at 30 DAI and afterward, the ischemic group maintained more th

17 6-day after imbibition (6-HAI, 3-DAI, and 6-DAI) were performed to characterize the regulatory mecha

18 and IL12p70 in plasma of infected pigs at 7 DAI and augmented bronchoalveolar lavage (BAL) eosinophi

19 italization and mortality: low, defined as a DAI less than 0.2; medium, defined as a DAI of 0.2 to le

20 as a DAI less than 0.2; medium, defined as a DAI of 0.2 to less than 0.35; and high, defined as a DAI

21 .2 to less than 0.35; and high, defined as a DAI of 0.35 or higher.

22 and stained for amyloid precursor protein, a DAI marker.

23 Utilizing a DAI rat model, the current investigation examined the ro

24 restored in DAI(-/-) mice, consistent with a DAI-RIP3 complex being the natural target of vIRA.

25 significantly reduced the disease activity (DAI).

26 performed to determine mRNA levels of AIM2, DAI, and TLRs (TLR-1 through TLR-9).

27 nucleic acid surveillance proteins ADAR1 and DAI.

28 The expression of TLR-9, AIM2, and DAI in gingival tissues was further confirmed using immu

29 her confirmed expression of TLR-9, AIM2, and DAI in gingival tissues.

30 erferon-stimulated genes, such as CXCL10 and DAI.

31 The EAA and DAI association was consistent across 3 common diagnoses

32 Z-DNA-binding protein 1 (ZBP1; also known as DAI or DLM-1) is a nucleic acid sensor that contains two

33 These include ZBP1 (also known as DAI or DLM-1), which induces necroptosis, an inflammator

34 ZBP1 (Z-DNA binding protein 1; also known as DAI or DLM1) from activating RIPK3 upstream of MLKL.

35 acid binding protein 1 (ZBP1; also known as DAI) drives IFN-stimulated cell death in settings of RIP

36 e activity of mammalian cells (also known as DAI, P1-eIF-2, and p68 kinase).

37 " and "fast-action" mitigation to help avoid DAI and abrupt climate changes.

38 nt inverse relationship was observed between DAI score and Ki-67 marker in the crude model and the ad

39 s used to determine the relationship between DAI and pathological markers.

40 re found significantly increased, while both DAI and health transition on general health scores were

41 orchestrated by the sensing of infection by DAI/ZBP-1, engagement of the kinase RIPK3, and subsequen

42 related with DNA binding activity results by DAI.

43 Induction of class II genes by DAIs was accompanied by activation of a repressed class

44 c acid-binding protein 1 (ZBP1) (also called DAI and DLM1), and TIR domain-containing adapter-inducin

45 eic-acid-binding protein (ZBP)1 (also called DAI or DLM1) contributes to innate host defense against

46 This aspect of the CGC-DAI method was illustrated by the online analysis of fre

47 ers in cases from individuals with confirmed DAI and control human brain tissue using multiplex immun

48 s of climate change that might be considered DAI, authors of the Third Assessment Report (TAR) of the

49 rations of greenhouse gases would constitute DAI, a value judgment that would be policy prescriptive.

50 Cells lacking DAI or containing DAI mutants deficient in nucleic acid binding are resist

51 of a continuous intake against a continuous DAI was also performed.

52 sor protein (APP) immunoreactivity to define DAI severity.

53 pendent activator of IFN-regulatory factors (DAI) that contain receptor-interacting protein (RIP) hom

54 activator of interferon-regulatory factors (DAI), and absent in melanoma 2 (AIM2) in chronic periodo

55 activator of interferon regulatory factors (DAI, also known as ZBP1 or DLM-1) sensitizes cells to vi

56 sting a spectrum of possible definitions for DAI.

57 istic global average temperature metrics for DAI with probability distributions of future climate cha

58 These studies unveil a role for DAI as the RIP3 partner mediating virus-induced necrosis

59 likelihood of avoiding a given threshold for DAI depends in part on uncertainty in the climate system

60 es are even more under-represented in global DAI than species-rich, developing countries in the tropi

61 SW MR imaging depicted 1,038 hemorrhagic DAI lesions with an apparent total hemorrhage volume of

62 The majority (59%) of individual hemorrhagic DAI lesions seen on SW MR images were small in area (<10

63 vors in the low DAI group, those in the high DAI group experienced 3.7 more years of EAA (beta = 3.66

64 ng survivors younger than 30 years, the high DAI group experienced 4.9 more years of EAA vs the low D

65 These results identify DAI as a link between IAV replication and RIPK3 activati

66 we designed the DNA affinity immunoblotting (DAI) method to measure the activities of multiple sequen

67 plication and RIPK3 activation and implicate DAI as a sensor of RNA viruses.

68 In DAI, liquid aerosol droplets are delivered directly to t

69 iffusion tensor MRI parameters may change in DAI lesions; however, the nature of these changes is inc

70 ine in frailty status, defined as decline in DAI from robust (T1) to prefrail or frail (T2).

71 ving as a matrix, controls ion generation in DAI for systems spanning simple binary and more complex

72 vIRA mutant MCMV pathogenesis is restored in DAI(-/-) mice, consistent with a DAI-RIP3 complex being

73 reproduces human TBI consequences, including DAI and clinical sequelae such as memory impairment.

74 assessed by the deficit accumulation index (DAI) and categorized as low, medium, and high risk.

75 The deficit accumulation index (DAI) uses readily available clinical data to measure phy

76 status, using a Deficit Accumulation Index (DAI; categorized as robust, prefrail, and frail), at T1

77 histological damage, disease activity index (DAI) and SCFA concentration in stools.

78 TO-curcumin improved disease activity index (DAI) dose-dependently, while the anti-inflammatory effic

79 ht, food intake, and disease activity index (DAI) were assessed throughout the study, and at 21 or 24

80 tcomes (weight loss, disease activity index (DAI)), anastomotic healing scores (endoscopic, histologi

81 -Ex reduced colitis, disease activity index (DAI), and histological colitis scores, and increased the

82 with MCIBDQ, SF-36, disease activity index (DAI), marriage, employment and economic burden questionn

83 by the reduction of disease activity index (DAI), restoration of colonic histological damage and sup

84 index (ODI) and dispersion anisotropy index (DAI) across several cortical and subcortical regions, co

85 The dietary antioxidant index (DAI) was calculated using dietary intakes derived from a

86 nship between the dietary antioxidant index (DAI) with pathological markers (tumor size and Ki-67 mar

87 Upon infection, DAI recognizes IAV genomic RNA, associates with RIPK3, a

88 Gaps in digital accessible information (DAI) on species distributions hamper prospects of safegu

89 we show that histone deacetylase inhibitors (DAIs) that alter the acetylation of histones in chromati

90 hallmarks of TBI are diffuse axonal injury (DAI) and microglial activation.

91 I, are insensitive to diffuse axonal injury (DAI) caused by trauma.

92 omising drug to treat diffuse axonal injury (DAI) caused by traumatic brain injury, using two differe

93 Diffuse axonal injury (DAI) is one of the most common and important pathologies

94 y (TBI), particularly diffuse axonal injury (DAI), often results in sympathetic hyperactivity, which

95 It produces diffuse axonal injury (DAI), which contributes to cognitive impairment, but eff

96 s, most likely due to diffuse axonal injury (DAI).

97 TBI) characterized by diffuse axonal injury (DAI).

98 aumatic brain damage [diffuse axonal injury (DAI)] occurs in such children has not yet been reliably

99 oil alone per os on days after inoculation (DAI) -1, +1, and +3 with infective eggs.

100 on of "dangerous anthropogenic interference (DAI) with the climate system." However, success will be

101 revent dangerous anthropogenic interference (DAI) with the climate system." In an effort to provide s

102 e of "dangerous anthropogenic interference" (DAI).

103 Knockdown of DNA Activator of Interferon (DAI) and p204, the murine ortholog to IFI16, had minimal

104 Droplet-assisted ionization (DAI) mass spectrometry is a promising and straightforwar

105 ectrometry with droplet-assisted ionization (DAI).

106 nt activator of IFN regulatory factors (IRF; DAI, also known as ZBP1 or DLM-1) is a cytosolic DNA sen

107 , MDA5, and DNA-dependent activator of IRFs (DAI), use TBK1/IKKe as the terminal kinases to activate

108 ker expression up to 60 days after ischemia (DAI).

109 ion (DAE) and differential allelic isoforms (DAI) from the phased full-length isoform reads.

110 Cells lacking DAI or containing DAI mutants deficient in nucleic acid

111 experienced 4.9 more years of EAA vs the low DAI group (beta = 4.95; 95% CI, 2.14-7.75; P < .001).

112 Compared with survivors in the low DAI group, those in the high DAI group experienced 3.7 m

113 experienced greater EAA vs those in the low DAI group.

114 variates, participants with less than median DAI values had an increased risk of H. pylori onset (adj

115 stic leukemia survivors, those in the medium DAI group (beta = 2.27; 95% CI, 0.78-3.76; P = .001) exp

116 4.85; P < .001), whereas those in the medium DAI group experienced 1.8 more years of EAA (beta = 1.77

117 y young is diffuse hypoxic brain damage, not DAI, can be explained in one of two ways: either the unm

118 letal breakdown as a possible contributor of DAI after repeated blast exposure.

119 ide non-invasive biomarkers for detection of DAI, which is the pathological substrate for neurologica

120 re has the potential to improve diagnosis of DAI.

121 cilitate a more widespread implementation of DAI for aerosol chemical analysis in different applicati

122 ogical analysis showed significant levels of DAI at the frontal cortex and cerebellum at multiple tim

123 amyloid precursor protein (APP), a marker of DAI.

124 plays a major role in the pathophysiology of DAI.

125 The role of DAI in activation of NF-kappaB in response to immunostim

126 e genes cannot be explained by the effect of DAIs on the cell cycle or enhanced apoptosis.

127 eep modulation after trauma has an impact on DAI and memory outcome.

128 thogenicity was restored in either RIPK3- or DAI-deficient mice.

129 s with its upstream adaptors RIPK1, TRIF, or DAI to signal for necroptosis in response to death recep

130 can mitigate microglial M1 polarization post-DAI, effectively curtailing sympathetic hyperactivity.

131 s with RIP3 and this interaction potentiates DAI-mediated activation of NF-kappaB, implicating RIP3 i

132 ry, corresponding with improved preoperative DAI (P=0.03) and both endoscopic (POD3:P<0.0103; POD7:P<

133 ith regard to their potential for preventing DAI.

134 e N terminus of the VACV E3 protein prevents DAI-mediated induction of necroptosis.

135 t exposed to the forces necessary to produce DAI.

136 s more potent than that with MSC in reducing DAI, the histological score, and nitrite levels.

137 ind that outside a few well-sampled regions, DAI on point occurrences provides very limited and spati

138 RIP3 binding to one of three partners-RIP1, DAI, or TRIF-via a common RIP homotypic interaction moti

139 in programmed necrosis induced by RIP1-RIP3, DAI-RIP3, and TRIF-RIP3 complexes.

140 encoded Zalpha domain-containing DNA sensor, DAI.

141 A variety of DNA sensors (DAI, AIM2, DDx41, RNA polymerase [Pol] III, and IFI16 [p

142 red to control white matter, mild and severe DAI lesions contained significantly larger abnormal T1-T

143 -appearing white matter from mild and severe DAI lesions, with significantly larger abnormal T1-T2 an

144 zes cells to virus-induced necrosis and that DAI knockdown or knockout cells are resistant to this de

145 We report that DAI (ZBP1/DLM-1), previously implicated as a cytoplasmic

146 The DAI included 44 aging-related items, such as chronic hea

147 The DAI method is largely independent of the distance betwee

148 sociations between mean LTL residual and the DAI.

149 ls, we evaluated the association between the DAI and H. pylori infection risk.

150 Both the DAI and EAA were effective at identifying aging phenotyp

151 etary antioxidant intake, as measured by the DAI, may be associated with a lower risk of breast cance

152 Also, by entering the DAI as a quantitative variable in model 3 of logistic re

153 ve and qualitative (quartiles) scores of the DAI, with 95% CI.

154 urvivors of childhood cancer showed that the DAI was associated with EAA, suggesting an underlying bi

155 These DAI results were categorized based on reported associati

156 Thus, DAI interacts with RIP3 to mediate virus-induced necrosi

157 volve the previously described sensors TLR9, DAI, RNA polymerase-III or IFI16/p204.

158 toskeletal proteins in the brain can lead to DAI, and evaluated alpha-II spectrin degradation in the

159 nvestigate T1-T2-diffusion changes linked to DAI and to define their histopathological correlates.

160 pite a similar level of mRNA upregulation to DAI/ZBP1, or by cyclic GMP-AMP synthase (cGAS), despite

161 The mean of total DAI was significantly higher in controls (7.67) when com

162 components that are strongly associated with DAI and used them to generate axonal injury images.

163 tion motif (RHIM)-dependent interaction with DAI.

164 inactivation of RIPK1, RIPK3, TRIF and ZBP1/DAI and inhibition of tumour necrosis factor (TNF), lipo

165 taining proteins RIPK1, RIPK3, TRIF and ZBP1/DAI during infection.