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1 DALY effects positively correlated with moderate and sev
2 DALY rates for ischaemic heart disease were greater in u
3 DALY rates in rural areas were at least twice those of u
4 DALY risk factors varied by age, with child and maternal
5 DALYs averted would increase by 14.9% with access to new
6 DALYs averted would increase by 44.2% if an HbA(1c) of 8
7 DALYs for the various device/voltage combinations were l
8 DALYs were half of those globally (55.7 per 100 000 [49.
9 ated population experienced a burden of 40.0 DALYs (95% CI 29.5-52.0) per 1000 population per year fr
12 would avert 240,000 (95% UI 65,000-530,000) DALYs across their lifetime (i.e., followed from 2015 th
14 was beneficial, the median benefit was 28.1 DALYs averted per 10 000 children receiving MNPs (IQR 20
17 result in an estimated health burden of 112 DALYs, and ED would lead to a reduction of 15 DALYs in e
18 ter treatment would avert an additional 1179 DALYs (-1769 to 4377) over 10 years at an expected addit
21 (95% CI -57 266 to 97 790) and averting 176 DALYs (133 to 226), leading to a cost of -$98 (-497 to 3
23 imated to avert 15 cases, 12 deaths, and 243 DALYs per 1000 vaccinated girls, and the nonavalent HPV
24 12 months of secondary IPT would avert 2472 DALYs (95% UI -888 to 7801) over a 10-year period and is
26 lation) and central sub-Saharan Africa (2988 DALYs per 100 000) followed by the other sub-Saharan Afr
27 2017, resulting in 22.9 million (21.5-24.3) DALYs (15.1% of the total NCD burden), after the group o
28 1.1-2.7) deaths and 60.9 million (34.6-93.3) DALYs in 2017, with the burden overwhelmingly experience
29 d congenital heart anomaly burden (1629/3049 DALYs per 100 000) was attributed to behavioral or metab
32 ere estimated to induce a total burden of 33 DALYs, dominated by PM2.5 impacts from rail transport em
33 ble NCD burden were highest in Oceania (3564 DALYs per 100 000 of the population) and central sub-Sah
36 lts cost $310-$1666/case averted ($731-$4017/DALY averted) in Honduras, saved $953-$1703/case averted
39 ildren cost $718-$1849/case averted (<=$5002/DALY averted) in Honduras, saved $819-$1609/case averted
41 2017, francophone Africa experienced 53 570 DALYs (50 164-57 361) per 100 000 population, distribute
45 or nonhealthcare water systems with a 10(-6) DALY pppy target (the more conservative target) would re
48 00 population) due to NCDs in 2017 (21 757.7 DALYs [95% UI 19 377.1-24 380.7]) was almost equivalent
49 rate of age-related burden ranged from 137.8 DALYs (128.9-148.3) per 1000 adults in high SDI countrie
50 and lowest in Australia and New Zealand (803 DALYs per 100 000) followed by other high-income regions
51 uld avert ~45,000 deaths, at a cost of $2.84/DALY (95% uncertainty interval [UI]: 1.71-5.57) averted.
52 uld avert ~186,000 deaths at a cost of $4.89/DALY averted (95% UI: 2.88-11.42), MDA to all under-5 ch
53 l cohort of 1000 pregnant women, averted 892 DALYs (95% credibility interval 274 to 1517) at an incre
55 rent treatment levels, which lowered to 32.9 DALYs (24.4-44.7) under WHO PEN implementation and to 32
56 e countries (LMICs; 60.8 million [34.6-92.9] DALYs) compared with high-income countries (0.09 million
57 to bring population health benefits (10 990 DALYs averted per year) and to be cost-saving (by $2.9 m
61 dardised rates for the incidence, deaths and DALY were 4.9 (95% UI: 4.7-5.1), 1.7 (95% UI: 1.6-1.8) a
63 , whereas the age-standardised mortality and DALY rates decreased by 44.3% (41.1-48.9) and 48.1% (44.
65 (0.45-0.89) to 0.87 million (0.61-1.18); and DALYs from 31.7 million (30.2-33.3) to 42.5 million (39.
67 enario, we projected health system costs and DALYs averted with respect to the current status quo of
72 ty was estimated first and the incidence and DALYs were calculated based on the estimated mortality v
74 ulin, international units (IU) required, and DALYs averted per year under alternative treatment algor
76 ntraumatic OHCA is a leading cause of annual DALY in the US and should be a focus of public health po
80 t of ED ranged from - 138 to + 1,326 avoided DALYs (90% confidence), with a median of - 11 avoided DA
81 uming 100% coverage, produced a net benefit (DALYs averted) in 54 countries (24 in Africa, 19 in Asia
84 HCV prevalence estimates and cardiovascular DALYs for 100 countries to estimate country-level burden
88 concentrations with a per-exposure-corrected DALY target at each conventional fixture would be 1.06 x
92 ntal cost per averted cardiovascular disease DALY (calculated using the incremental cost-effectivenes
97 ld with a neural tube defect incurs an extra DALY per year for the remainder of the time horizon and
100 cohol misuse was the highest risk factor for DALYs (7.0% overall, 10.5% for males, and 2.7% for femal
106 .3), and east Asia (56.5), with the greatest DALY burdens in children, adolescents, and the elderly.
109 f China experienced a substantial decline in DALY rates from all injuries ranging from 16.3% (3.1-28.
110 o fetal losses was included and decreases in DALYs when comprehensive CT prevention measures were con
111 ase in deaths averted, and a 72% increase in DALYs averted per 1000 vaccinated girls for both the biv
114 (95% CI 1827 to 9448) and 107.4 incremental DALYs averted (-719.7 to 904.1) per 1000 women; the aver
115 e-times variation in age-standardised injury DALY rates between provinces of China, with the lowest v
120 CV infection was responsible for 1.5 million DALYs, with the highest burden in low-income and middle-
122 global burden of melioidosis was 4.6 million DALYs (UI 3.2-6.6) or 84.3 per 100 000 people (57.5-120.
123 gastric cancer due to H pylori (14.6 million DALYs), cirrhosis and other chronic liver diseases due t
124 rs were found in China and India (66 million DALYs), a number greater than all developed countries co
125 ing 143 million (95% UI: 133 to 153 million) DALYs, 6.55 million (95% UI: 6.00 to 7.02 million) death
126 ing 182 million (95% UI: 170 to 194 million) DALYs, 9.14 million (95% UI: 8.40 to 9.74 million) death
127 of 4.1 million (1.6 million to 6.8 million) DALYs from chronic obstructive pulmonary disease in 2015
129 op 15 conditions that accounted for the most DALYs were mostly those causing mortality (ischaemic hea
132 l population burden of disease of 16 735 net DALYs per year for a country with an adult population si
141 th other developing countries (around 50% of DALYs attributable to non-communicable disease), whereas
143 s highest in Qatar and accounted for 4.9% of DALYs, followed by 4.8% in the United Arab Emirates, whe
144 actors accounted for 34.5% (32.4 to 36.9) of DALYs; the two leading behavioural risk factors were unh
147 , childhood wasting was the leading cause of DALYs in Afghanistan, Somalia, and Yemen, whereas unsafe
148 cable risk factors were the leading cause of DALYs in high-income and middle-income countries in the
156 -adjusted life-years (DALYs) by quintiles of DALYs annual increase from 1990 to 2013 to show rates of
159 l services-treated OHCA, and to compare OHCA DALY to other leading causes of death and disability in
165 DALY), compared with tuberculosis ($156 per DALY), malaria ($125 per DALY), and pneumonia ($33 per D
171 egy costs US$1,843 (95% CI 1,328-14,312) per DALY averted during this period and that effective geogr
173 l horizon was Int$168 (95% UI 55 to 337) per DALY averted in China, $154 (57 to 289) in India, $88 (1
176 gross domestic product per capita ($487) per DALY averted, and remain robust over a wide range of epi
177 a cost effectiveness threshold of US$500 per DALY averted, and discounted DALYs and costs at 3% per y
178 ountries assuming a WTP of at least $500 per DALY averted, in 51 with assumed WTP values of at least
182 cost-effectiveness ratio (ICER) of $540 per DALY averted, $645 per life-year saved, and $511 per QAL
183 ving of US$24 902 (95% CI 14 666-62 579) per DALY averted compared with a saving of $17 587 (1840-42
184 , scenario A resulted in an ICER of $582 per DALY averted and scenario B resulted in an ICER of $411
185 d the greatest relative investment ($772 per DALY), compared with tuberculosis ($156 per DALY), malar
186 $197 (90% model variability -27 to 863) per DALY averted; results remained cost-effective when varyi
189 gross domestic product (GDP) per capita per DALY averted, at a vaccine price of $1.50 per dose (but
190 io with low hospitalisation levels (cost per DALY averted $690, 143 to 1379), although the CIMIC prog
192 o with high hospitalisation levels (cost per DALY averted -$512, 95% CI -872 to -115) but with a high
193 Cost-effectiveness was presented as cost per DALY averted and death averted, with probabilistic sensi
194 ts are presented as the incremental cost per DALY averted and the likelihood that an intervention is
195 We predicted that the incremental cost per DALY averted of continuing PCV would be $153 (95% PI 70-
201 as a direct result of oral diseases is rare, DALY estimates were based on years lived with disability
203 uld produce modest health benefits, reducing DALYs from atherosclerotic cardiovascular disease among
205 perienced a decrease in the age-standardised DALY and mortality rates due to injury, despite an incre
206 tion growth and ageing, the age-standardised DALY rate (per 100 000 population) due to NCDs in 2017 (
209 world regions of east Asia (age-standardised DALYs 136.32), southeast Asia (134.57), Oceania (120.34)
210 bies burden were Indonesia (age-standardised DALYs 153.86), China (138.25), Timor-Leste (136.67), Van
211 gest standard deviations of age-standardised DALYs between the 20 age groups were observed in southea
212 1990 to 2017, and compared age-standardised DALYs due to injuries at the provincial level against th
216 from 66.0 to 66.3, ASDR and age-standardized DALY rate decreased from 17.1 to 16.5 and 532.9 to 510.7
217 ized death rate (ASDR), and age-standardized DALY rate increased for LC from 11.1 to 11.8, 10.1 to 10
218 en 1990 and 2017, DALYs and age-standardized DALY rates significantly declined (-3.4% and -33%, respe
227 cting an increase in the proportion of total DALYs attributable to NCDs (from 18.6% [95% UI 17.1-20.4
229 ounted for 98.9% (UI 97.7-99.5) of the total DALYs, and years lived with disability accounted for 1.1
231 f disease due to incident hip fracture using DALYs in prospective cohorts in the CHANCES consortium,
232 documents of less than 1000 CFU per L, while DALY-based guidance suggests lower critical concentratio
234 , US$166) per Disability Adjusted Life Year (DALY) averted, PMI-funded interventions are highly cost-
236 ncidence, and disability-adjusted life year (DALY) estimates of oral conditions for the period of 199
237 the costs per disability-adjusted life-year (DALY) averted and associated 95% prediction intervals (P
239 st US$200 per disability-adjusted life-year (DALY) averted, or assuming a WTP value of at least 25% o
242 were cost per disability-adjusted life-year (DALY) averted; cost per life-year saved; and cost per qu
244 d ($790-$4221/disability-adjusted life-year [DALY] averted) in Honduras, and saved $847-$1644/case av
246 Background Disability-adjusted life years (DALY) are a common public health metric used to consiste
249 l trends for disability-adjusted life years (DALYs) and years of life lost also increased significant
251 ortality and disability-adjusted life years (DALYs) associated with kidney cancer in 195 countries, f
252 he number of disability-adjusted life years (DALYs) averted by a hydrocelectomy and identified the co
253 r estimating disability-adjusted life years (DALYs) from the Global Burden of Disease Study; and heal
256 n deaths and disability-adjusted life years (DALYs) lost if eight proven vehicle safety technologies
257 , mortality, disability-adjusted life years (DALYs), and years lived with disability (YLD) from 1990
258 ing per 2017 disability-adjusted life years (DALYs), HIV/AIDS received the greatest relative investme
264 e calculated disability-adjusted life-years (DALYs) arising from stillbirths, neonatal death, low bir
265 all cost and disability-adjusted life-years (DALYs) associated with annual follow-up examinations and
266 roke-related disability-adjusted life-years (DALYs) associated with potentially modifiable environmen
267 losses, and disability-adjusted life-years (DALYs) attributable to physical inactivity were estimate
269 ulin use and disability-adjusted life-years (DALYs) averted by insulin use, given that current access
270 , deaths, or disability-adjusted life-years (DALYs) averted per 1000 vaccinated girls in comparison w
271 me was total disability-adjusted life-years (DALYs) averted through treatment of all cardiovascular d
272 deaths, and disability-adjusted life-years (DALYs) averted were calculated over a 15 year time horiz
274 quantiles of disability-adjusted life-years (DALYs) by quintiles of DALYs annual increase from 1990 t
275 e calculated disability adjusted life-years (DALYs) for each policy, assuming that a woman having a c
277 to calculate disability-adjusted life-years (DALYs) for these causes in eight age groups covering rur
278 fraction and disability-adjusted life-years (DALYs) from HCV-associated cardiovascular disease at the
279 5.1 million) disability-adjusted life-years (DALYs) in 2015, representing 7.6% of total global deaths
280 ve estimated disability-adjusted life-years (DALYs) lost due to hip fractures using real-life follow-
283 rtality, and disability-adjusted life-years (DALYs) related to chronic liver disease (primary liver c
284 We used disability-adjusted life-years (DALYs) to measure the negative health outcomes associate
285 ing cause of disability-adjusted life-years (DALYs) was ischaemic heart disease for males and lower r
289 ability, and disability-adjusted life-years (DALYs), for cancer overall and 30 cancer sites using dat
290 sed rates of disability-adjusted life-years (DALYs), for geographical regions as defined by the GBD.
291 and 13.0% of disability-adjusted life-years (DALYs), instead of the earlier estimates suggesting 21.2
292 lity (YLDs), disability-adjusted life-years (DALYs), life expectancy, and healthy life expectancy (HA
293 lity (YLDs), disability-adjusted life-years (DALYs), summary exposure values (SEVs), and attributable
294 measured by disability-adjusted life-years (DALYs), were estimated from 2000 to 2017 using exposure
295 try-specific disability-adjusted life-years (DALYs), years lived with disability (YLDs), and years of
296 ce of cases, disability-adjusted life-years (DALYs), years lived with disability, and years of life l
297 in terms of disability-adjusted life-years (DALYs)-with crude counts as well as all-age and age-stan
299 tion risk vs disability adjusted life years [DALY] on a per-exposure or annual basis), and fixture ty
300 th outcomes (disability-adjusted life-years [DALYs] due to communicable, maternal, and nutritional di