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1 DCA (10-150 microM) stimulated the release of both Hbeta
2 DCA (50-250 micromol/L) caused profound Ca2+ release fro
3 DCA - RQ storage was associated with the activation of t
4 DCA also caused dramatic translocation of PH-PLCdelta-GF
5 DCA and similar approaches that use sequence information
6 DCA and taurodeoxycholic acid (TDCA) (100 micromol/L) ca
7 DCA can accurately infer spatial adjacencies between res
8 DCA did not affect RPP but normalized dP/dt in HYP.
9 DCA forces CSCs into oxidative phosphorylation but does
10 DCA had no effect on localization of a novel (PKCdelta)
11 DCA induced cAMP formation at the plasma membrane and cy
12 DCA induced mild, transient colonic inflammation within
13 DCA induces mild, transient colitis, resulting in persis
14 DCA involvement in these disease processes results partl
15 DCA is based on three features, primarily the previously
16 DCA is currently not approved for cancer treatment in th
17 DCA is shown to yield a large number of correctly predic
18 DCA promoted minority MOMP noted by minimal release of c
19 DCA showed minimal net benefit.
20 DCA stimulated phosphorylation of the p65 subunit of NF-
21 DCA stimulated TGR5 redistribution to plasma membrane mi
22 DCA storage reduces ACC (1-aminocyclopropane-1-carboxyla
23 DCA treatment restored cardiac mitochondrial membrane po
24 DCA was also found to induce tyrosine phosphorylation an
25 DCA, taurolithocholic acid, and oleanolic acid did not s
26 DCA-CF is efficient in quality maintenance of 'Royal Gal
27 DCA-RQ1.5 is the most suited for the storage of 'Fuji Su
28 ) day(-1) simvastatin + 30 mg kg(-1) day(-1) DCA (n = 9) or 88 mg kg(-1) day(-1) simvastatin + 40 mg
30 ane (1,1,1-TCA); and 1,1-dichloroethane (1,1-DCA), range from -26.5 per thousand to -1.8 per thousand
33 icroarray analyses revealed a cluster of 142 DCA- and INA-responsive genes that show a pattern of dif
34 When aseptic root cultures were fed [14C]-DCA, compared with wild types, the ugt72B1 plants showed
36 nisms controlling natural attenuation of 1,2-DCA and to design appropriate strategies to enhance biod
37 sed to characterize dihaloelimination of 1,2-DCA by different bacteria, which needs to be confirmed i
38 rination are the proposed mechanisms for 1,2-DCA degradation by coupled nZVI-dithionite treatment.
39 tterns allow for the first time reliable 1,2-DCA degradation pathway identification in the field, whi
42 and anaerobic biodegradation pathways of 1,2-DCA in the field and suggests that this approach might a
45 lcitrance toward abiotic dechlorination, 1,2-DCA remains a challenging compound for the remediation c
46 nd-specific chlorine isotope analysis of 1,2-DCA was performed for the first time, and isotope fracti
51 ic biodegradation of 1,2-dichloroethane (1,2-DCA) via dihaloelimination by Dehalococcoides and Dehalo
52 ic biodegradation of 1,2-dichloroethane (1,2-DCA) via oxidative cleavage of a C-H bond (Pseudomonas s
56 phere monitored by respiratory quotient 1.3 (DCA-RQ 1.3) showed lower ethylene production, respiratio
57 and its metabolite 3,4-dichloroaniline (3,4-DCA) on thyroid function and metamorphosis in tadpoles o
58 phere monitored by respiratory quotient 1.5 (DCA-RQ 1.5) increased the acetaldehyde, ethanol and ethy
59 apples can be stored at 3 degrees C using a DCA system, based either on CF or on RQ, to save electri
60 correlation with viral stability, whereas a DCA-derived metric was highly correlated with virus tran
62 ck-out or knockdown of p53 or CD95 abolished DCA + MEK1/2 inhibitor-induced PERK phosphorylation and
63 ific bile acids, and the secondary bile acid DCA in particular, in the regulation of hepatic LCFA upt
65 e the secondary bile acids deoxycholic acid (DCA) and lithocholic acid (LCA), which accumulate at con
66 vestigating the effects of deoxycholic acid (DCA) and ursodeoxycholic acid on the expression and rele
67 Secondary bile acids like deoxycholic acid (DCA) are well-established tumor promoters that may exert
68 eoxycholic acid (UDCA) and deoxycholic acid (DCA) as the two most potent inhibitors of the liver-spec
70 ry bile acids (BA) such as deoxycholic acid (DCA) promote the development of several gastrointestinal
71 a-linolenic acid (DGLA) to deoxycholic acid (DCA) species (DCAS) was significantly increased in obese
74 uct of secondary bile acid deoxycholic acid (DCA), at as low as 50 uM, inhibited 82.8% of C. perfring
77 holic acid (T-betaMCA) and deoxycholic acid (DCA), induce proliferation and DNA damage in Lgr5(+) cel
79 ta-cyclodextrin suppressed deoxycholic acid (DCA)-induced apoptosis, and staining for cholesterol wit
80 revealed the presence of Dichloracetic acid (DCA) as the active antitumor constituent of Chaetomorpha
81 sulfoxide (DMSO) and 5% dichloroacetic acid (DCA) and successive heteronuclear (1)H-(15)N HSQC spectr
83 epresentative, 3,5-dichloroanthranilic acid (DCA), efficiently induced defense reactions to the phyto
85 Conjugating lipids (e.g. docosanoic acid, DCA) to siRNA supports extrahepatic delivery, but tissue
86 s of Purkinje cells, nearly universal across DCAs, dysregulates the dentatothalamocortical network.
87 Genera previously associated with aerobic DCA biodegradation (Xanthobacter, Ancylobacter, Azoarcus
89 )-alkylmethylammonium dicyanamide ([Aliquat][DCA]) and 1-n-octyl-3-methylimidazolium dicyanamide ([Om
96 consC3 outperforms direct coupling analysis (DCA) methods significantly independent on family size, s
98 based entirely on Direct Coupling Analysis (DCA) of correlated mutations in multiple sequence alignm
99 t constraints from direct coupling analysis (DCA) to determine the dominant docked conformation of th
100 d this model using direct coupling analysis (DCA), a powerful statistical inference method that has b
107 xycholic acid in unconjugated (CDCA, CA, and DCA) and tauro-conjugated (t-CDCA, t-CA, t-DCA) form on
110 ty related to the values obtained by RFA and DCA devices, which could create disagreements and miscom
111 is had been made in various regions; RFA and DCA should have been applied in the same implants and pe
113 which specific bile acids, such as UDCA and DCA, can impact hepatic triglyceride metabolism and may
114 al cases of a few protein families and apply DCA to a systematic large-scale study of nearly 2,000 Pf
117 tory quotient dynamic controlled atmosphere (DCA - RQ), which induces ethanol production through low
118 en (ULO) with dynamic controlled atmosphere (DCA) and controlled atmosphere (CA) on the post storage
119 he effects of dynamic controlled atmosphere (DCA) storage based on chlorophyll fluorescence (DCA-CF)
120 a' apples, in dynamic controlled atmosphere (DCA), treated with or without 1-methylcyclopropene (1-MC
122 n and cell-cycle progression, and attenuated DCA-induced colorectal cancer or PDAC tumorigenicity.
123 ine ACR was measured by nurses using a Bayer DCA 2000 analyzer and expressed in mg/mmol (reference ra
124 Expression of dominant negative PERK blocked DCA + MEK1/2 inhibitor-induced expression of ATG5, GRP78
125 TILs) [emim][BF(4)], [emim][DCA], and [bmim][DCA] at 25 degrees C from below 1 GHz to 10 THz by ultra
126 th butylmethylpyrrolidinium-dicyanamide (BMP-DCA) IL shows high sensitivity toward ascorbic acid (AA)
131 t alter ERK1/2 and AKT activation induced by DCA or CDCA but abolished pathway activations by conjuga
132 findings suggest that contacts predicted by DCA can be used as a reliable guide to facilitate comput
133 aluate the accuracy of contact prediction by DCA for a large number of protein domains, based purely
135 e older group, FMT signal in dorsal caudate (DCA) and dorsal putamen was greater with age, suggesting
137 lmitoleic acid and the deoxycholate/cholate (DCA/CA) ratio, along with the dysregulation scores of 3
138 ibitors, our findings suggest that combining DCA with a DNA methylation inhibitor would offer a means
145 DK) inhibitor/PDH activator dichloroacetate (DCA) normalizes HPMC metabolism, reduces lactate secreti
146 se complex (PDC) activator, dichloroacetate (DCA), would blunt activation of FOXO gene targets and re
148 Inhibiting PDK3 activity by dichloroacetate (DCA) or siRNA-mediated attenuation was sufficient to inc
150 e effect of the orphan drug dichloroacetate (DCA) on survival in an animal model of hemorrhagic shock
152 ochondrial kinase inhibitor dichloroacetate (DCA) has recently received attention in oncology due to
153 ed the potential neurotoxin dichloroacetate (DCA) was investigated using an intermediate-pressure mat
154 ained untreated or received dichloroacetate (DCA) to activate PDH and increase substrate competition
155 of PDH by cell exposure to dichloroacetate (DCA) increased production of hyperpolarized 5-(13)C-glut
156 Herein, it is shown that dichloroacetone (DCA) enhances helical secondary structures when introduc
159 ionic liquids (RTILs) [emim][BF(4)], [emim][DCA], and [bmim][DCA] at 25 degrees C from below 1 GHz t
161 pression of p21 or p27(Kip-1) (p27) enhanced DCA + MEK1/2 inhibitor toxicity in primary hepatocytes t
162 expression of p21 or p27 profoundly enhanced DCA + MEK1/2 inhibitor-induced expression of ATG5 and GR
164 c acid (ent-CDCA), and deoxycholic acid (ent-DCA) to induce toxicity and apoptosis in HT-29 and HCT-1
165 ve completed the successful synthesis of ent-DCA in 25 steps with a yield of 0.3% with all stereochem
166 critical micelle concentration (cmc) of ent-DCA, determined by a dye solubilization method, was iden
167 olon cancer cell lines demonstrated that ent-DCA had similar effects on proliferation, yet showed a m
170 ) storage based on chlorophyll fluorescence (DCA-CF) and respiratory quotient (DCA-RQ) on the quality
171 tient (DCA-RQ) and chlorophyll fluorescence (DCA-CF) on anaerobic metabolism, physiological storage d
174 stic increases in apparent IC(50) values for DCA, whereas binding affinities for DCA are comparable w
177 onexpresser of Pathogenesis-Related genes1), DCA acts transiently and is only partially dependent on
184 Interestingly, reduced anaplerosis in HYP+DCA corresponded with normalized TAG (14.9+/-0.6 micromo
186 cifically, we show that AREG participates in DCA-induced EGFR and STAT3 signaling, cell-cycle progres
193 mediated silencing of TGR5 or AREG inhibited DCA-induced EGFR, MAPK, and STAT3 signaling, blunted cyc
195 group folded only 11 of them by integrating DCA-predicted contacts into fragment-based conformation
196 hybrid method, called DCA-fold, integrating DCA contacts with an accurate knowledge of local informa
199 A) of myoelectrical activity within the left DCA muscle in half of this horse population and the hors
202 alogenase gene dhlA was developed to monitor DCA-degrading bacteria in the MBR, and a positive correl
203 zed compounds, we have selected the multiple DCA-loaded compound 10, characterized by a tertiary amin
212 n studies together with a new application of DCA to the eukaryotic proteins NAF-1 and Bcl-2 provided
215 r would offer a means to reduce the doses of DCA to avoid detrimental effects associated with high do
216 kinase resistant to the inhibitory effect of DCA, thereby uncoupling the active site from the alloste
222 s it was concluded that the glucosylation of DCA may not be as effective in xenobiotic detoxification
224 Nonetheless, despite the clear impact of DCA and LCA on host physiology, an incomplete knowledge
225 computationally efficient implementation of DCA, which allows us to evaluate the accuracy of contact
228 ar differential effects on the metabolism of DCA and TCP were obtained in whole plant studies with wi
230 tridium sporogenes, conferring production of DCA and LCA on a nonproducing commensal and demonstratin
231 Rs can be an effective method for removal of DCA from groundwater, and that the dhlA qPCR is a rapid
232 ctyl-3-methylimidazolium dicyanamide ([Omim][DCA]) inside the porous structure of ceramic membranes.
233 othioate (PS) content, linker composition-on DCA-conjugated siRNA delivery and efficacy in vivo.
237 in the colon compared to Cj-P0, while Cj-P1-DCA-Anaero showed reduction of the inflammatory gene exp
243 In conclusion, microbial metabolic product DCA prevents NE-induced BW loss and ileal inflammation t
244 N-benzyl-3-(3,4 dihydroxyphenyl)propanamide (DCA) and phosphatidylcholine (PC) was explored in a 6-da
245 tmosphere monitored by respiratory quotient (DCA-RQ) and chlorophyll fluorescence (DCA-CF) on anaerob
246 orescence (DCA-CF) and respiratory quotient (DCA-RQ) on the quality and volatile profile of 'Royal Ga
247 tmosphere monitored by respiratory quotient (DCA-RQ) with three fruit maturity stages at harvest (ear
249 Regret-based decision curve analysis (Regret-DCA) was performed on a Cox's regression model developed
252 ethyladenine or knockdown of ATG5 suppressed DCA + MEK1/2 inhibitor-induced LC3-GFP vesicularization
253 d DCA) and tauro-conjugated (t-CDCA, t-CA, t-DCA) form on human ENaC in its alphabetagamma- and delta
255 ction were less variable (2-fold range) than DCA production (5-fold range), although the uncertainty
258 cell lines under BA treatment revealed that DCA and its conjugated form, TDCA, significantly inhibit
259 nally, fluorescence anisotropy revealed that DCA causes a decrease in membrane fluidity consistent wi
261 ing for cholesterol with filipin showed that DCA caused a marked rearrangement of this lipid in the m
264 otif in mediating communications between the DCA-, the nucleotide-, and the lipoyl domain-binding sit
267 he absence of fluid resuscitation; therefore DCA may be a good candidate in prolonged field care foll
269 One-year exposure of Barrett's cells to DCA induced a malignant phenotype noted by clone and tum
270 osure of colorectal cancer and PDAC cells to DCA resulted in colocalization of Src and TACE to the ce
277 dically reduced conjugating activity towards DCA and TCP and the absence of immunodetectable UGT72B1
279 )CHCl(2))(2)Cl(2)], mitaplatin, in which two DCA units are appended to the axial positions of a six-c
284 h firmness was higher in fruits stored under DCA-CF and ULO differing from CA, in the year 2012, but
285 acetate), as compared to fruit stored under DCA-CF, but fruit stored under DCA-RQ 1.5 and RQ 2.0 als
287 stored under DCA-CF, but fruit stored under DCA-RQ 1.5 and RQ 2.0 also showed higher amounts of key
289 Data are consistent with a model in which DCA directly induces both Ca2+ release from internal sto
291 ater anaerobic metabolism in comparison with DCA - CF (chlorophyll fluorescence) and controlled atmos