ライフサイエンスコーパス: DEHP

1 DEHP and non-DEHP factor scores were not associated with

2 DEHP concentrations in ECMO patients were greater in the

3 DEHP concentrations were the highest of the phthalates m

4 DEHP is a high production volume chemical associated wit

5 DEHP is in fact a plastic contaminant always presents on

6 DEHP leached from circuit A at 0.32 +/- 0.12 microgram/

7 DEHP leaches from ECMO circuits, with potential exposure

8 DEHP was also found at notable concentrations in product

9 DEHP was the major phthalate found in 99% of the samples

10 DEHP-induced elevations in serum testosterone and E2 lev

11 The most important findings are (1) DEHP steady-state concentrations increased greatly with

12 In protocol 2, DEHP was undetected in the control patients.

13 PCA identified a DEHP component and a non-DEHP component.

14 As yet, little is known about DEHP effects in utero on fetal Leydig cells (FLC).

15 The proportion of airborne DEHP in the particle phase was experimentally observed t

16 All DEHP plasma concentrations were measured by gas chromato

17 d ratios were found across gestation for all DEHP [di(2-ethylhexyl) phthalate] metabolites.

18 jor phthalate diesters (DiBP, DnBP, BBzP and DEHP) monitoring in food items has been developed and va

19 %, 12.0% and 14.1%, for DiBP, DnBP, BBzP and DEHP, respectively.

20 D patients, urinary levels of DEP, BBzP, and DEHP metabolites declined significantly during this peri

21 deaths would have been attributed to BPA and DEHP between 2003 and 2015.

22 If exposures to BPA and DEHP in the United States had been at 2015 levels since

23 During the bonne chauffe, DBP and DEHP accumulated in the secondes more than in the brandy

24 ch type showed the presence of DIBP, DBP and DEHP at concentrations up to 44.2 +/- 2.1 ng/g of wet we

25 The concentration of DBP and DEHP in hot-water samples from plastic bags were found i

26 ion of highly hydrophobic compounds, DBP and DEHP.

27 sed, finding concentrations of DBP, DEHA and DEHP in the range 29.3-734 ng/capsule, below the tolerab

28 essed Poc14's potential to hydrolyse DEP and DEHP after residue mutations, resulting in the Poc14-AAG

29 3.25 ng/mL), DEP (7.07 +/- 7.59 ng/mL), and DEHP (3.48 +/- 1.02 ng/mL) were found to be the most pre

30 dogs (n = 11) and incubated with PCB153 and DEHP, independently and combined, at 0x, 2x, 10x and 100

31 table concentrations in products labeled as "DEHP-free".

32 ective cohorts report that gestational BBzP, DEHP, di-butyl phthalate (DBP), and di-ethyl phthalate (

33 Besides DEHP, 29% of the samples contained other ortho-phthalate

34 r regression models and associations between DEHP metabolites and clinical outcomes using logistic re

35 significantly positive correlations between DEHP daily intake and urinary 5OH-MEHP, 5oxo-MEHP, and 5

36 After corrections for method blank DEHP, co-eluting compounds, and unidentified carbon, the

37 We estimate BPA, DEHP, and PBDE exposures in 38 countries containing one-

38 ee model radiolabeled molecules, namely BPA, DEHP and 4n-NP.

39 icrobiome-gut-immune axis can be modified by DEHP and emphasize the value of multiomics approaches to

40 ry glycine, which inactivates Kupffer cells, DEHP did not increase radical signals.

41 nd relative concentrations of each chemical (DEHP.PCB interaction for: DNA fragmentation; human p < 0

42 showed almost no leaching from the circuit; DEHP concentrations decreased at a rate of 0.2 +/- 0.04

43 as induced in male rats by a diet containing DEHP and clofibrate for 3-60 days.

44 ade three different plasticizers (i.e., DBP, DEHP, and ATBC) via a comprehensive proteogenomic and me

45 Safety Improvement Act of 2008, may decrease DEHP exposure, but additional work characterizing the na

46 DC in coffee powder (60 %), followed by DEP, DEHP, BPA, and BPF (20 % each).

47 Among 12 investigated EDCs, only DEP, DEHP, DnBP, BPA, and BPF were found in packed coffee (20

48 the phthalates diisobutyl phthalate (DiBP), DEHP, diisononyl phthalate (DINP), and diisodecyl phthal

49 tances (PFASs), metabolites of diethylhexyl (DEHP) and diisononyl (DiNP) phthalates, PCB-153, and p,p

50 enced by the severity of kidney dysfunction: DEHP and BBzP exposure showed negative associations with

51 PCA, one representing the di(2-ethylhexyl) (DEHP) and another non-DEHP metabolites.

52 -weight (HMW), and di-2-ethylhexylphthalate (DEHP) metabolites, controlling for sex, television watch

53 ctive, comparative clinical study evaluating DEHP plasma concentrations in ECMO vs. non-ECMO patients

54 The authors examined DEHP exposure in relation to the timing of labor in a pr

55 Paternal lineage F3 DEHP males exhibited decreased fertility, testicular ste

56 nancy, or early pregnancy loss, and in fact, DEHP [di(2-ethylhexyl) phthalate] metabolites {MEOHP [mo

57 l system, male and female zebrafish were fed DEHP (3 ppm) daily for two months.

58 The impact on pregnancy following DEHP exposure and the associated interaction of high fat

59 king (+27% for DEHP), and sleeping (-26% for DEHP).

60 showering (-71% for BBzP), cooking (+27% for DEHP), and sleeping (-26% for DEHP).

61 and synthetic musks in the gas phase and for DEHP, DiBP, DBP, and DINP in the airborne particles.

62 f the particle-gas partition coefficient for DEHP.

63 Daily plasma concentrations for DEHP were collected until 3 days after decannulation fro

64 thyl phthalate (DMP) to 0.673 mug/kg/day for DEHP.

65 t by the EU (30 mg/kg for BBP, 1.5 mg/kg for DEHP, 0.3 mg/kg for DBP, and 9 mg/kg for DINP and DIDP).

66 75-500 ng/mL for DBP and 150-1000 ng/mL for DEHP.

67 Relationships with OHdG were significant for DEHP metabolites as well as mono-n-butyl phthalate (MBP)

68 The estimated DI values for DEHP in 39 individuals were above the U.S. Environmental

69 The findings indicated that the values for DEHP, DINP, DEP, and DBP were all below 1, indicating ne

70 zed urine samples from eight adults for four DEHP metabolites [mono(2-ethylhexyl) phthalate, mono(2-e

71 and occupational and clinical exposures from DEHP-plasticized medical devices, e.g., blood bags, hemo

72 Furthermore, DEHP given with [(13)C(2)]dimethyl sulfoxide produced a

73 8-11% of children less than 2 years old had DEHP exposure estimates exceeding cancer benchmarks.

74 The indoor particles acquired a higher DEHP fraction than laboratory-generated ammonium sulfate

75 The highest DEHP exposure dose of 730 mug/kg bw/day was determined f

76 identifies a novel pathway modulating human DEHP toxicity with potential clinical implications for a

77 The discovery that CAR2 is an ultimate human DEHP receptor identifies a novel pathway modulating huma

78 Importantly, DEHP increased oxidant production in wild-type but not i

79 viously unknown mitochondrial dysfunction in DEHP-induced testicular toxicity and highlight the impor

80 y partially mimicked the effects observed in DEHP-treated cells.

81 ical pregnancy and live birth for individual DEHP metabolites.

82 Intriguingly, DEHP appeared to inhibit DNA replication as evidenced by

83 4% in rats receiving 10, 100, and 750 mg/kg DEHP, respectively.

84 control after exposures to 100 and 750 mg/kg DEHP, respectively.

85 c-Kit ligand (KITL) were induced by 10 mg/kg DEHP.

86 On a class level, DEHP exposure increased Bacteroidia and Gammaproteobacte

87 At the transcriptome level, DEHP significantly upregulated gene networks in the inte

88 NCH-an alternative to legacy phthalates like DEHP, whose primary metabolite MINCH has been linked to

89 e than one sample may be necessary for MBzP, DEHP, and BPA.

90 In the N-of-1 trials, mean DEHP removal rates range from 95.9% (SD = 0.1%) to 97.0%

91 The measured DEHP partition coefficient to ammonium sulfate particles

92 Twenty percent of the modeled DEHP exposure occurred between 2200 hours and 0500 hours

93 washing with soap-and-water removes 80% more DEHP than handwashing with water alone, and may be a cos

94 PCA identified a DEHP component and a non-DEHP component.

95 Interactions between sex and non-DEHP component association with outcomes were statistica

96 DEHP and non-DEHP factor scores were not associated with serum TSH, T

97 the di(2-ethylhexyl) (DEHP) and another non-DEHP metabolites.

98 In boys, higher maternal non-DEHP, but not DEHP, component scores were associated wit

99 Contrary to hypotheses, prenatal non-DEHP phthalate exposures were associated with lower BMI

100 In boys, higher maternal non-DEHP, but not DEHP, component scores were associated with lower BMI z-

101 alue of 2.5-fold 2 h after administration of DEHP, before peroxisomal oxidases were induced.

102 This amount of DEHP extrapolates in the ECMO patient to a potential exp

103 home from 23 to 35 degrees C, the amount of DEHP in the gas- and particle-phase combined is predicte

104 Poc14-AAG could hydrolyse one bond of DEHP and diester bonds of DEP.

105 ol to determine the surface concentration of DEHP.

106 Testicular concentrations of DEHP and PCB153 perturbed sperm viability, motility and

107 trations of PBDE and lower concentrations of DEHP and PCBs.

108 n urine and by determining concentrations of DEHP in exposure media (e.g., air, food, dust).

109 cked model, future average concentrations of DEHP in PVC flooring on the Swiss market are expected to

110 Although significant concentrations of DEHP leach from the nonheparin-bonded circuits over time

111 mated associations between concentrations of DEHP metabolites and gestational age at delivery using l

112 Urinary concentrations of DEHP metabolites were inversely associated with oocyte y

113 The gas-phase concentrations of DEHP versus time were measured at air flow rate of 450 m

114 The content of DEHP in VF was measured at about 15% (w/w) using pressur

115 ed to the vehicle or 20 or 200 mug/kg/day of DEHP from gestation day 11 until birth.

116 error method to determine times and doses of DEHP that resulted in a best fit of predicted and observ

117 DEHP toxicity we investigated the effect of DEHP on DNA replication.

118 We assessed the effect of DEHP on gene expression using microarray analysis.

119 The present study investigated effects of DEHP on FLC function.

120 ota may contribute to the adverse effects of DEHP on the host by altering metabolites sensed by both

121 e provided approximately 250 mug extracts of DEHP with carbon purity ranging from 92.5 +/- 1.2% (n =

122 first report of the contemporary fraction of DEHP isolated from market butter in the U.S.

123 The adsorption isotherm of DEHP on the stainless steel chamber surfaces was explici

124 mice to an environmentally relevant level of DEHP did not affect pregnancy.

125 g gestation and exposed to the same level of DEHP display marked impairment in placental development,

126 The level of DEHP metabolites showed a negative association with the

127 and one was found containing 453.67 ng/mL of DEHP.

128 e typical mouse, rat, and marmoset models of DEHP toxicity cannot accurately profile potential human

129 sion rate and to measure the partitioning of DEHP onto airborne particles.

130 The strong partitioning of DEHP onto the stainless steel surface was found to follo

131 adjustment, women at the 75th percentile of DEHP metabolite concentrations had a 2-day-longer mean l

132 Various concentrations (1-100 ppm) of DEHP in deionized MilliQ water were tested using the fun

133 than 1%, whereas the migration quotients of DEHP were higher than 2.0%.

134 esults demonstrate that the emission rate of DEHP is substantially enhanced in the presence of partic

135 t it takes several weeks for the sorption of DEHP onto the stainless steel surface to reach equilibri

136 e (DEHP) and could be an important source of DEHP in homes.

137 (95% CI): 1.19 (1.06, 1.35) for molar sum of DEHP metabolites and 1.22 (1.01, 1.47) for BPA] at media

138 The numbers of Leydig cells in the testis of DEHP-treated rats were 40-60% higher than in control rat

139 Furthermore, the toxicity of DEHP led to respiratory chain defects and attenuation of

140 cause of the extensive production and use of DEHP, humans are exposed to this chemical daily.

141 xposure by back calculating intakes based on DEHP metabolite concentrations in urine and by determini

142 0.03-0.20 mug mL(-1), respectively, but only DEHP was found in clear chicken soup samples in the rang

143 l remediation, with potential for optimising DEHP degradation and exploring dimerisation effects.

144 associations were not significant for HMW or DEHP metabolites, and results did not change substantial

145 s female rats received vehicle (corn oil) or DEHP at 10, 100, or 750 mg/kg by oral gavage from gestat

146 ree samples were measured for four oxidative DEHP metabolites, mono-(2-ethyl-5-hydroxyhexyl) phthalat

147 to 245 mug/m(3), the total (gas + particle) DEHP concentrations increased by a factor of 3 to 8; und

148 the idea that interactions between gas-phase DEHP and soiled surfaces have been reduced to interactio

149 model prediction and the observed gas-phase DEHP chamber concentrations.

150 and 2 +/- 1 m, respectively), (3) gas-phase DEHP concentration in equilibrium with the vinyl floorin

151 were pretreated with diethylhexyl phthalate (DEHP) and butyl benzyl phthalate (BBP), and were stimula

152 , bisphenol A (BPA), diethylhexyl phthalate (DEHP) and mineral oil hydrocarbons (MOHs), are evaluated

153 eport the effects of diethylhexyl phthalate (DEHP) and polychlorinated biphenyl 153 (PCB153) on DNA f

154 ECs, including diethylhexyl phthalate (DEHP) and polychlorinated bisphenol 153 (PCB153), were d

155 rs were dominated by diethylhexyl phthalate (DEHP), although emerging plasticizers (e.g., diethylhexy

156 r pressure compound, diethylhexyl phthalate (DEHP), mainly through production of particulate matter d

157 ve concentrations of diethylhexyl phthalate (DEHP), polybrominated diphenyl ethers (PBDE) and polychl

158 isphenol A (BPA) and diethylhexyl phthalate (DEHP), which are widespread environmental contaminants d

159 dhood exposure to di-2-ethylhexyl phthalate (DEHP) and butylbenzyl phthalate (BBzP) may increase the

160 he metabolites of di-2-ethylhexyl phthalate (DEHP) and dibutyl phthalate (DBP), in addition to monobe

161 The emission of di-2-ethylhexyl phthalate (DEHP) from vinyl flooring (VF) was measured in specially

162 halate (BBzP) and di-2-ethylhexyl phthalate (DEHP) in residential indoor environments and the influen

163 tric means of the di-2-ethylhexyl phthalate (DEHP) metabolites mono-(2-ethyl)-hexyl phthalate (MEHP)

164 coefficient K of di-2-ethylhexyl phthalate (DEHP) on typical impervious surfaces including aluminum,

165 alate (BBzP), and di-2-ethylhexyl phthalate (DEHP) that span a wide range of gas-particle partitionin

166 s, metabolites of di-2-ethylhexyl phthalate (DEHP) were associated with increased IL-6 and IL-10 but

167 ocrine disruptor, di-2-ethylhexyl phthalate (DEHP), and the severity of impacted reproductive traits

168 hemicals, such as di-2-ethylhexyl phthalate (DEHP), for which the gut lumen may even exceed the liver

169 (DCHP) to 74% for di-2-ethylhexyl phthalate (DEHP).

170 r metabolites of di(2-ethylhexyl) phthalate (DEHP) [percent difference (%Delta)=-2.83 to -2.16].

171 Rats were given di(2-ethylhexyl) phthalate (DEHP) acutely.

172 Di(2-ethylhexyl) phthalate (DEHP) and butyl benzyl phthalate (BBzP) were the dominan

173 contained > 10% bis(2-ethylhexyl) phthalate (DEHP) and could be an important source of DEHP in homes.

174 lates, including di(2-ethylhexyl) phthalate (DEHP) and di-n-butyl phthalate (DBP), have been shown to

175 halates, namely, di(2-ethylhexyl) phthalate (DEHP) and mono(3-carboxypropyl) phthalate (MCPP), and 34

176 ate (MnBP)], and di(2-ethylhexyl) phthalate (DEHP) are being replaced by substitutes including other

177 late (BBzP), and di(2-ethylhexyl) phthalate (DEHP) based on NAS recommendations, and included diethyl

178 t not long-chain di(2-ethylhexyl) phthalate (DEHP) due to steric hindrance.

179 ](+) ion of the bis(2-ethylhexyl) phthalate (DEHP) for performing the exact mass measurements of the

180 Emissions of di-(2-ethylhexyl) phthalate (DEHP) from one type of polyvinylchloride (PVC) flooring

181 pate (DEHA) and bis(2-ethylhexyl) phthalate (DEHP) from PVC flooring on damp surfaces alone is not su

182 Exposures to di-(2-ethylhexyl) phthalate (DEHP) have been shown to be associated with decreased ad

183 alate (DBP) and di-2-(ethylhexyl) phthalate (DEHP) in packaged food prior to analysis by gas chromato

184 alate (DBP) and di-(2-ethylhexyl) phthalate (DEHP) in soft drinks.

185 Di-(2-ethylhexyl) phthalate (DEHP) is a plasticizer used in consumer and medical prod

186 Di(2-ethylhexyl) phthalate (DEHP) is a synthetic chemical commonly used for its plas

187 n industry, and di-(2-ethylhexyl) phthalate (DEHP) is the most abundant phthalate in the environment.

188 t phthalates, 4 di-(2-ethylhexyl) phthalate (DEHP) metabolites (Sigma4DEHP) and mono-benzyl phthalate

189 ), compared with di(2-ethylhexyl) phthalate (DEHP) metabolites.

190 ectivity for the di(2-ethylhexyl) phthalate (DEHP) molecule.

191 stillate, while bis(2-ethylhexyl) phthalate (DEHP) only partially, and diisononyl phthalate (DINP) ac

192 itate (TOTM) and di(2-ethylhexyl) phthalate (DEHP) were the predominant plasticizers in PMDs used for

193 e metabolites of di(2-ethylhexyl) phthalate (DEHP)) and Sigma14phthalates (sum of 14 urinary phthalat

194 rally produced bis (2-ethylhexyl) phthalate (DEHP), a ubiquitous plasticizer known to contaminate pac

195 metabolites of di-(2-ethylhexyl) phthalate (DEHP), and BPA.

196 hthalate (DnBP), di(2-ethylhexyl) phthalate (DEHP), and diethyl phthalate (DEP).

197 mon plasticizer, di(2-ethylhexyl) phthalate (DEHP), as a highly potent and uniquely selective agonist

198 l phthalate (DEP), (2-ethylhexyl) phthalate (DEHP), di-(2-ethylhexyl) adipate (DEHA), di-isononyl pht

199 essment covering di(2-ethylhexyl) phthalate (DEHP), di-n-butyl phthalate (DnBP), di-isobutyl phthalat

200 f six phthalates-di(2-ethylhexyl) phthalate (DEHP), di-n-octyl-, di-iso-butyl-, di-n-butyl-, butylben

201 phthalate (BBP), di(2-ethylhexyl) phthalate (DEHP), diisobutyl phthalate (DIBP), dicyclohexyl phthala

202 ee plasticizers: di(2-ethylhexyl) phthalate (DEHP), diisononyl phthalate (DiNP), and di(2-ethylhexyl)

203 henol A (BPA), bis (2-ethylhexyl) phthalate (DEHP), nonylphenol monoethoxylate (NMP) and nonylphenol

204 a metabolite of di(2-ethylhexyl) phthalate (DEHP), the percent of the total effect mediated by 8-iso

205 Di(2-ethylhexyl) phthalate (DEHP), used primarily as a plasticizer for polyvinyl chl

206 enol A (BPA) and di(2-ethylhexyl) phthalate (DEHP)-and a class of chemicals-brominated flame retardan

207 he results from di-(2-ethylhexyl) phthalate (DEHP)-treated HepG2 cells revealed that the minimal VLCA

208 halates such as di-2-(ethylhexyl) phthalate (DEHP).

209 mainly lead and bis(2-ethylhexyl) phthalate (DEHP).

210 , filled with a bis(2-ethylhexyl) phthalate (DEHP).

211 tes, especially di-(2-ethylhexyl) phthalate (DEHP); however, the underlying mechanisms are unknown.

212 sphenol-A (BPA), bis(2-ethylhexyl)phthalate (DEHP) and dibutyl phthalate (DBP) at two different doses

213 Di(2-ethylhexyl)phthalate (DEHP) and diisononyl phthalate (DINP) were the most abun

214 urinary oxidative di(2-ethylhexyl)phthalate (DEHP) metabolites, our proxy for exposure to DEHP-tainte

215 al efficiency of di-(2-ethylhexyl)phthalate (DEHP) on hands by handwashing with soap-and-water versus

216 ned the effect of di(2-ethylhexyl)phthalate (DEHP) on the metabolic profile of cardiomyocytes because

217 ed metabolites of di(2-ethylhexyl)phthalate (DEHP) were also reduced (27%; not statistically signific

218 ome proliferators di(2-ethylhexyl)phthalate (DEHP), clofibrate, and 4-chloro-6-(2,3 xylidino)-2-pyrim

219 15 of 46 labeled "di(2-ethylhexyl)phthalate (DEHP)-free"), first aid products (n = 13), and intraveno

220 ation products of di(2-ethylhexyl)phthalate (DEHP).

221 , retinoate, and bis(2-ethylhexyl)phthalate (DEHP).

222 Di-(2-ethylhexyl)-phthalate (DEHP) is a ubiquitously used endocrine disruptor.There i

223 sure emissions of di-2-ethylhexyl-phthalate (DEHP) from vinyl flooring, with ammonium sulfate particl

224 late (DBP) and bis(2-ethyl hexyl) phthalate (DEHP), are now increasingly being replaced with more env

225 phthalate [DBP], di(2-ethylhexyl) phthalate [DEHP]) decreased, while those of di-isobutyl phthalate [

226 phthalate ester (di(2-ethylhexyl)phthalate) (DEHP), a known endocrine disruptor, contributed by appro

227 DE-28) to 4200 (bis(2-ethylhexyl) phthalate, DEHP) for dust removal.

228 phthalate, DCHP; di(2-ethylhexyl) phthalate, DEHP; di-n-octyl phthalate, DNOP; diisononyl phthalate,

229 ldren 4-9 years of age, though high prenatal DEHP exposure may be associated with lower fat mass in c

230 droxyhexyl) phthalate (MEHHP), the principal DEHP metabolite, and the risk of uterine leiomyoma diagn

231 bon, the mean fraction of naturally produced DEHP in butter was determined to be 0.16 +/- 0.12 (n = 5

232 rface is close to the vapor pressure of pure DEHP, and (4) with an increase of temperature in a home

233 By feeding male rats DEHP for 2 weeks, rat spermatogenesis became disrupted,

234 average daily mean and median reconstructed DEHP doses were 10.9 and 5.0 microg/kg-day, respectively

235 ic exposures to low environmentally relevant DEHP levels on testicular function.

236 vations show that DEHTP has rapidly replaced DEHP and exposure to several phthalates adversely influe

237 In two three-day N-of-1 trials, residual DEHP was measured in a single female adult who washed ex

238 In Ukrainian children, the PC3 score (DEHP) was positively associated with current wheeze (adj

239 In adjusted models, MEHP, MECPP, and Sigma DEHP metabolites were associated with significantly incr

240 (2-ethyl-5-oxohexyl) phthalate, MECPP, Sigma DEHP, MBP, and mono-(3-carboxypropyl) phthalate metaboli

241 s a result of the introduction of only small DEHP plasticizer molecules.

242 The particles rapidly sorb DEHP from the gas phase, allowing more to be emitted fro

243 osol (typically fresh traffic exhaust) sorbs DEHP more efficiently than aged organic aerosol.

244 ith ischemic heart disease (IHD) and stroke, DEHP exposure with increased all-cause mortality among p

245 We conclude that DEHP and PCB153, at known tissue concentrations, induce

246 resonance spectrum, providing evidence that DEHP stimulates (*)OH radical formation in vivo.

247 roke were associated with BPA exposure; that DEHP exposures were linked to approximately 164,000 deat

248 We found that DEHP contributed most to summation operatorandrogen-disr

249 n vitro, consistent with the hypothesis that DEHP induced FLC aggregation.

250 repeated measures analysis, we reported that DEHP metabolites and BPA were significantly associated w

251 and mammalian two-hybrid assays reveal that DEHP activates CAR2 at low nanomolar concentrations, res

252 Our study further reveals that DEHP exposure combined with a HF diet interfere with the

253 Migration assessment showed that DEHP, DnBP, and BPF amounts were significantly higher af

254 Data suggest that DEHP exposure results in metabolic remodeling of cardiom

255 These data suggest that DEHP may interfere with signaling related to the timing

256 The DEHP-particle sorption equilibration time was demonstrat

257 This transgenerational difference in the DEHP impact can be attributed specifically to the Y chro

258 pared to women in the lowest quintile of the DEHP factor scores, women in the highest quintile had si

259 er time, our in vivo studies showed that the DEHP plasma concentrations were less than the previously

260 Fast food may be a source of exposure to DEHP and DiNP.

261 Although exposure to DEHP and/or PCB153 alone increased DNA fragmentation and

262 -term complications from chronic exposure to DEHP have not been determined.

263 ne disruptor.There is widespread exposure to DEHP in the general population which has raised substant

264 Daily human exposure to DEHP in the U.S. is significant, and occupational and cl

265 Exposure to DEHP led to up-regulation of genes associated with fatty

266 DEHP) metabolites, our proxy for exposure to DEHP-tainted foodstuffs in children </=10 years, during

267 n together, indicate that fetal exposures to DEHP have effects on FLC number, distribution, and most

268 hed the minimal VLCAD promoter's response to DEHP treatment.

269 up-regulate VLCAD expression in response to DEHP treatment.

270 es appeared to be particularly vulnerable to DEHP toxicity we investigated the effect of DEHP on DNA

271 In conclusion, urinary DEHP metabolites decreased progressively in children aft

272 Mixtures of urinary DEHP metabolites were inversely associated with serum bi

273 (PVC) flooring with approximately 13% (w/w) DEHP as plasticizer were measured in the Field and Labor

274 ing increased risk of allergic diseases with DEHP and BBzP exposure.

275 alibrated on a single person self-dosed with DEHP in conjunction with the eight participants' data, w

276 eonatal rat cardiomyocytes were treated with DEHP at a concentration and duration comparable to clini

277 otransformation products of two xenobiotics, DEHP and 4'-Methoxy-alpha-pyrrolidinopentiophenone (4-Me