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1 DFP 1 mg/mL in drinking water increased retinal Tfrc mRN
2 DFP at 60 muM decreased labile iron in ARPE-19 cells, in
3 DFP exposure elicited comparable effects on phosphorylat
4 DFP formation (Kcat and kcat/Km), DFP decay, and protein
5 DFP has also been known to elicit antiproliferative acti
6 DFP treated rats, exhibited significantly reduced expres
7 DFP treatment significantly altered phosphorylation at r
8 DFP was not retina toxic in wild-type (WT) or DKO mice,
11 t with [3H]diisopropylphosphofluoridate ([3H]DFP) to produce radioactive adducts that can be resolved
15 ith the laminin-derived peptide EFPDFP and a DFP peptide from the random screen demonstrated binding
16 ays, and allografting techniques to define a DFP state and the mechanism that governs its differentia
18 this end, we developed a rat model of acute DFP intoxication and evaluated the efficacy of NV354 as
19 ed phase of learning impairment to sub-acute DFP exposure, which may involve the loss of hippocampal
23 ent complications but safely protect against DFP-induced seizures and other CNS toxicity, we adopted
24 Da for the active site peptide peak of aged DFP-inhibited NEST, corresponding to a monoisopropyl pho
25 parathion, and dimefox, and the nerve agents DFP, tabun, sarin, cyclosarin, soman, VX, and Russian-VX
28 e DFP) with IMI (2 mg/kg s.c., 30 min before DFP) prevents DFP-induced convulsions and the associated
29 ion of HUP (50 microg/kg s.c., 15 min before DFP) with IMI (2 mg/kg s.c., 30 min before DFP) prevents
31 -pretreated mice, the ED(50) of IMI to block DFP-induced mortality is approximately 10 times lower th
40 axis with pyridostigmine bromide (PB) caused DFP-treated animals to exhibit near normal levels of mem
41 A recent report shows that the iron chelator DFP induces both mitophagy and pexophagy in a BNIP3/NIX-
45 he 3 drugs, deferoxamine (DFO), deferiprone (DFP), and deferasirox (DFX), including their efficacy, p
48 other hand, 1 mM diisopropylfluorophosphate (DFP) completely inhibited LCAT but had no effect on PAF-
51 os oxon (CPO) or diisopropylfluorophosphate (DFP): human serum albumin (K212, K414, K199, and K351),
52 amidine (pAB) and diisopropylfluorphosphate (DFP) were impaired 1.6-36-fold and 35-478-fold, respecti
53 (AChE) inhibitor, diisopropylflurophosphate (DFP) were administered as single daily injections concom
54 dition, low level diisopropylflurophosphate (DFP) exposure (0.25 mg/kg per day for 2 weeks) in rats r
59 benefits of the fermented and non-fermented DFP before in vitro digestion and after (bioaccessible f
62 groups such as diisopropyl fluorophosphate (DFP) or venomous agent X, creating a major challenge for
63 AChE inhibitor diisopropyl fluorophosphate (DFP) usually caused a sustained increase, with an initia
65 a CE inhibitor, diisopropyl fluorophosphate (DFP), to mouse serum in vitro significantly (P < 0.01) p
68 d with inactive diisopropyl-fluorophosphate [DFP]-thrombin) and mediated via the protease-activated r
69 complex with diisopropyl fluorophosphonate (DFP, a potent serine hydrolase inhibitor) were determine
70 n, anti-PRCP, diisopropyl-fluorophosphonate (DFP), phenylmethylsulfonyl fluoride (PMSF), and Z-Pro-Pr
71 5 and 1938 for dichlorvos, 1881 and 1994 for DFP, and 1838 and 1938 for sarin; these masses fit a mec
79 r piroxicam or the selective COX-2 inhibitor DFP, but by inhibitors of either secretory or cytosolic
80 that when the acetylcholinesterase inhibitor DFP was co-administered with morphine, both the increase
84 a nanostructured film of the small molecule DFP-4T, consisting of a fully pai-conjugated diperfluoro
85 M active sites enabled identification of new DFP-based KDM inhibitors which are more cytotoxic to can
86 ocompatibility and water dispersibility, nTG-DFP-COF demonstrates minimal cytotoxicity and exceptiona
87 a nanoscale Covalent Organic Framework, nTG-DFP-COF, specifically designed to enhance fluorescence-g
88 ing tumor targeting accuracy, the use of nTG-DFP-COF will reduce the need for repeat surgeries, facil
91 lation state of phosphoproteins in brains of DFP-treated mice; hippocampus and striatum were analyzed
102 tion of tau proteins by brain supernatant of DFP-treated hens that includes phosphorylation of a numb
107 93 is deleterious for interactions with pAB, DFP and amidolytic substrates, situations where no S2'-P
108 ubstrates are coupled via a diferric peroxo (DFP) intermediate, lambdamax 650 nm, which decays to [Fe
114 I (2 mg/kg s.c., 30 min before DFP) prevents DFP-induced convulsions and the associated neuronal dama
117 ith its monocyte chemotactic activity, since DFP- or PMSF-inactivated cathepsin G no longer induced m
119 the rate of endogenous ACh release, and that DFP and reversible AChE inhibitors exert an initial tran
122 to show a temporal relationship between the DFP-induced impairment in performance of a spatial memor
123 02(Zr) using Soxhlet extraction improved the DFP conversion rate and afforded a 2.64-fold improvement
124 domain, and central to the interaction, the DFP phenylalanine side-chain inserts into a major hydrop
127 icotine was shown to completely reverse this DFP-induced impairment in memory-related task performanc
128 lude that the level of sustained response to DFP is determined by the rate of endogenous ACh release,
132 binding equivalence concentrations at which DFP inhibits ribonucleotide reductase (RNR) activities a
133 as attenuated when Lp(a) was pretreated with DFP suggesting that the serine residue in the pseudo act