ライフサイエンスコーパス: DMPC

1 DMPC in the form of small unilamellar vesicles (SUVs) or

2 DMPC-binding assays demonstrate an identical vesicle cle

3 At 1:1 DMPC:[1-44]apoA-I (w/w) ratio, discoidal complexes with

4 mixture, and the analog MG-H2 in DMPC or 3:1 DMPC/DMPG membranes.

5 e the apparent melting temperature of apoC-1:DMPC complexes by up to 20 degrees C and decelerate prot

6 ominant electrostatic interactions in apoC-1:DMPC disks are destabilizing.

7 density profiles of our simulations of 1024 DMPC lipids.

8 imately 5 [1-44]apoA-I and approximately 150 DMPC molecules per disk.

9 ed the expected interaction with ApoE(1-191).DMPC, but surprisingly CR16-18 did not interact with thi

10 16-18 variant capable of binding ApoE(1-191).DMPC.

11 However, in contrast to 2F in 2F.DMPC, 4F in the 4F.DMPC complex is located closer to the

12 betaCH(2) protons in 4F.DMPC, but not in 2F.DMPC, complex.

13 4F.DMPC complex is different than in the 2F.DMPC complex as evidenced by the NOE between lipid 2.CH

14 These NOEs are absent in the 2F.DMPC complex.

15 he conformation of the DMPC sn-3 chain in 4F.DMPC complex is different than in the 2F.DMPC complex as

16 ies to deduce detailed structure of 4F in 4F.DMPC discs.

17 tween lipid 2.CH and betaCH(2) protons in 4F.DMPC, but not in 2F.DMPC, complex.

18 , in contrast to 2F in 2F.DMPC, 4F in the 4F.DMPC complex is located closer to the lipid headgroup as

19 heptapeptide anchor (ANCH) in water and in a DMPC (1,2-dimyristoyl-sn-glycero-3-phosphocholine) bilay

20 ucture of the full-length H-ras protein in a DMPC bilayer has been computationally characterized.

21 ower coupling (14%) when the peptide is in a DMPC bilayer suggests a high degree of peptide conformat

22 cs of caveolin-1 (D82-S136; Cav182-136) in a DMPC bilayer using NMR, fluorescence emission measuremen

23 MD simulations, both in DMSO and in a DMPC bilayer, showed sites of local stability of helical

24 urther refined using molecular dynamics in a DMPC bilayer.

25 A simulation in a DMPC/DMPG membrane did not lead to a stable pore, consis

26 Although only a DMPC membrane was considered in this work, we speculate

27 he permeation of Na(+) and Cl(-) ions across DMPC lipid bilayer by computing the corresponding potent

28 led Pf1 coat protein in magnetically aligned DMPC/DHPC bicelles.

29 MR spectra of MSI-78 in mechanically aligned DMPC bilayers.

30 the same polypeptide in mechanically-aligned DMPC and DOPC bilayers.

31 The pattern of anchor amide-DMPC phosphate/carbonyl hydrogen bonds and the flexibili

32 reorganization are unfavorable, whereas ANCH-DMPC interactions-especially van der Waals-favor inserti

33 evidenced by a number of NOEs between 4F and DMPC headgroup protons.

34 hyl-ammonio]-1-propane sulfonate (Chaps) and DMPC/l-alpha-1,2-dihexanoyl-sn-glycero-3-phosphocholine

35 C and POPC or a further decrease in DLPC and DMPC bilayers.

36 amic quantities characterizing pure DMPC and DMPC/cholesterol mixtures, thus directly confirming the

37 the volume expansion coefficient of DMPC and DMPC/Cholesterol samples with 13 and 25 mol% cholesterol

38 cs simulations of MAG2 performed in DMPC and DMPC/DMPG.

39 of DMPC, but the acyl chains in the EPL and DMPC bilayers occupy similar positions.

40 e of formation of rHDL from rcm apo A-II and DMPC at all FC mole percentages is faster than that of a

41 n the presence of both types of peptides and DMPC vesicles in the presence of nonselective peptides.

42 e aggregated in conventional DOPC, POPC, and DMPC membranes due to hydrophobic mismatch.

43 fect the BaP uptake rate by DMPC-NP-SLBs and DMPC-SUVs, indicating preferential BaP sorption into the

44 viability and growth using DMPC-NP-SLBs and DMPC-SUVs, with and without BaP, as their sole carbon so

45 on cooling from the heat-denatured state and DMPC clearance studies revealed that protein secondary s

46 -terminal lobe of LA5 in recognition of apoE-DMPC.

47 onolayers of ternary POPC/SM/Chol as well as DMPC/SM/Chol mixtures, which exhibit a surface-pressure-

48 probabilities for direct transitions between DMPC and DHPC were negligible, a third component with in

49 e as an intermediate for transitions between DMPC and DHPC.

50 he dynamics and structure of edges formed by DMPC and palmitoyl-oleoylphosphatidylethanolamine.

51 nd compare it to that in a bilayer formed by DMPC/DMPA lipids.

52 and the orientation of water is governed by DMPC.

53 Vesicles prepared by DMPC (1,2-dimyristoyl-sn-glycero-3-phosphocholine) and S

54 tter, does not affect the BaP uptake rate by DMPC-NP-SLBs and DMPC-SUVs, indicating preferential BaP

55 ing acyl chain length from 14 to 12 carbons (DMPC versus DLPC).

56 ith different chain lengths (14-carbon chain DMPC: 6-carbon chain DHPC) to find out whether a myriad

57 These well-characterised DMPC/DHPC bicelles enable us to probe the influence of b

58 but was alpha-helical in negatively charged DMPC/DMPG vesicles.

59 ion we obtained an rHDL structure comprising DMPC, cholesterol, and apolipoprotein AI (423:74:1 mol/m

60 ce 13C was observed from bicelles containing DMPC and DHPC lipid molecules.

61 (PCC) and the dorsomedial prefrontal cortex (DMPC).

62 istoylphosphatidylcholine (d54-DMPC) and d54-DMPC/dimyristoylphosphatidylglycerol (DMPG) were used to

63 uterated dimyristoylphosphatidylcholine (d54-DMPC) and d54-DMPC/dimyristoylphosphatidylglycerol (DMPG

64 shorter tail component (either DDPC in DDPC/DMPC mixtures or DMPC in DMPC/DSPC mixtures) extending 2

65 The diclofenac-DMPC interactions were clearly dependent on the drug's i

66 ade NLPs from dimyristoylphospatidylcholine (DMPC) in combination with each of four different apolipo

67 zipper, in a dimyristoylphosphatidylcholine (DMPC) membrane.

68 ally aligned dimyristoylphosphatidylcholine (DMPC) bilayers.

69 s containing dimyristoylphosphatidylcholine (DMPC, di-C(14) tails) and dihexanoylphosphatidylcholine

70 line (DLPC), dimyristoylphosphatidylcholine (DMPC), dioleoylphosphatidylcholine (DOPC), and 1-palmito

71 tituted from dimyristoylphosphatidylcholine (DMPC) and human apolipoprotein C-I (apoC-I, 6 kDa) or it

72 tituted from dimyristoylphosphatidylcholine (DMPC) and selected mutants of human apolipoprotein C-1 (

73 idylcholine (dimyristoylphosphatidylcholine (DMPC) and palmitoyloleoylphosphatidylcholine (POPC)) and

74 porated into dimyristoylphosphatidylcholine (DMPC) bilayers.

75 id phases of dimyristoylphosphatidylcholine (DMPC) and dilauroylphosphatidylcholine (DLPC) were obtai

76 crystals of dimyristoylphosphatidylcholine (DMPC) and diphytanoylphosphatidylcholine (DPhPC), and th

77 mulations of dimyristoylphosphatidylcholine (DMPC) bilayers to model the creation of bilayer gaps-a c

78 ilization of dimyristoylphosphatidylcholine (DMPC) membranes by apo A-I to give rHDL increases as the

79 ilization of dimyristoylphosphatidylcholine (DMPC) multilamellar vesicles by apolipoprotein A-I (apoA

80 permeabilize dimyristoylphosphatidylcholine (DMPC) and dimyristoylphosphatidylglycerol (DMPG) vesicle

81 osed of pure dimyristoylphosphatidylcholine (DMPC) or palmitoyl-oleoylphosphatidylethanolamine (POPE)

82 n solubilize dimyristoylphosphatidylcholine (DMPC) liposomes and fold into approximately 60% alpha-he

83 Using dimyristoylphosphatidylcholine (DMPC) as a model lipid, these domains can convert multil

84 neously when dimyristoylphosphatidylcholine (DMPC) large unilamellar vesicles (LUVs) were incubated w

85 DeltaG1 with dimyristoylphosphatidylcholine (DMPC) and 1-palmitoyl-2-oleoyl-phosphatdylcholine bilaye

86 teracts with dimyristoylphosphatidylcholine (DMPC) over a wide range of lipid:peptide ratios from 1:1

87 With dimyristoylphosphatidylcholine (DMPC) phospholipid vesicles with 100 microM Ca (2+) pres

88 -PLA(2) with dimyristoylphosphatidylcholine (DMPC) vesicles and found that specific residues 113-120

89 zwitterionic dimyristoylphosphatidylcholine (DMPC) bilayer coincubated with calcium ions.

90 membrane-mimetic dimyristoylphosphocholine (DMPC) or 1-palmitoyl-2-oleoyl-sn-glycerophosphocholine (

91 anism of pore formation and closure in DLPC, DMPC, and DPPC bilayers, with pore formation free energi

92 ster than approximately 10(5) s(-1) in DLPC, DMPC, and POPC bilayers, but the motion is slowed by 2 o

93 P31) and the lipid hydrophobic length (DLPC, DMPC, and DPPC), a wide range of mismatch conditions wer

94 on and fluid phase bilayers formed from DMPG/DMPC and POPG/POPC mixtures.

95 nstrated by the release of calcein from DMPG/DMPC vesicles and by propidium iodide influx experiments

96 Doping DMPC/DHPC bicelles with cholesterol sulfate broadens the

97 (m)): 41, 24, 7, and -20 degrees C for DPPC, DMPC, DLPC, and DOPC, respectively.

98 yers with different bilayer thickness, i.e., DMPC and POPC, the intramolecular distance reported by T

99 and 0.25 sterol mole fractions in ergosterol/DMPC mixtures.

100 m apolipoprotein AI, cholesterol, and excess DMPC and isolated to near homogeneity.

101 vesicles (SUVs) or DMPC-NP-SLBs with excess DMPC-SUVs to support colloidal stability, when added to

102 des areas per lipid A, 60.6 +/- 0.5 A(2) for DMPC and 63.2 +/- 0.5 A(2) for DLPC.

103 e has an area of 40.8 A(2) vs. 48.1 A(2) for DMPC.

104 al diclofenac displayed greater affinity for DMPC bilayers than anionic diclofenac.

105 combined to evaluate the drug's affinity for DMPC bilayers, as well as to assess the drug's effects o

106 lidate the new unilamellar vesicles data for DMPC, so method 4 is not required for DLPC or future stu

107 ept one of three independent simulations for DMPC and all three DLPC simulations, where the bilayer t

108 ta for the relative form factors F(q(z)) for DMPC were obtained using a combination of four methods.

109 coli polar lipids (EPLs), which differ from DMPC both in headgroups and acyl chains.

110 or shorter channels in liposomes formed from DMPC and for longer channels in DEPC.

111 this stoichiometry, apo A-II forms rHDL from DMPC and FC.

112 (w/v) phospholipid concentration and a high DMPC/DHPC ratio (q = 2.0) was found to be optimal for no

113 annel model was embedded in a fully hydrated DMPC lipid bilayer, and molecular-dynamics simulations w

114 complexes are similar to those of plasma A-I/DMPC complexes formed under similar conditions: small di

115 CD and EM studies of the apoA-I/DMPC complexes at different pH demonstrated that changes

116 Thermal unfolding of variant apoA-I/DMPC complexes monitored by circular dichroism (CD) show

117 A separate study was then conducted in DMPC liposomes in the presence of the putative membrane-

118 either DDPC in DDPC/DMPC mixtures or DMPC in DMPC/DSPC mixtures) extending 2-3 nm away from the prote

119 ces peptide-rich and peptide-poor domains in DMPC liposomes.

120 In contrast, spectra of GAsl in DMPC membranes indicate deeper embedding and tilt of the

121 ichiometric mixture, and the analog MG-H2 in DMPC or 3:1 DMPC/DMPG membranes.

122 havior of M2 transmembrane peptide (M2TM) in DMPC bilayers.

123 nal helix has a transmembrane orientation in DMPC bilayers, whereas in POPC bilayers, this domain is

124 R clearly indicates the presence of pairs in DMPC membranes.

125 ar-dynamics simulations of MAG2 performed in DMPC and DMPC/DMPG.

126 ssibly monomers and pentamers, is present in DMPC bilayers.

127 tra indicate that the presence of protein in DMPC results in a broad lipid phase transition that is s

128 that opsin can also be directly purified in DMPC/DHPC bicelles to give correctly folded functional o

129 of the on-time distributions of Nile Red in DMPC and SOPC vesicles were significantly different.

130 4 degrees (SKP in POPC), 22.3 degrees (SA in DMPC), and 31.7 degrees (SKP in DMPC).

131 grees (SA in DMPC), and 31.7 degrees (SKP in DMPC).

132 ly packed transmembrane melittin tetramer in DMPC shows formation of a toroidal pore after 1 mus.

133 ngle of 15 +/- 3 degrees in POPC, whereas in DMPC, 25 +/- 3 degree and 30 +/- 3 degree tilts were obs

134 ssociate with and dissociate from individual DMPC and SOPC vesicles adsorbed on a glass surface, gene

135 arkably, spontaneous insertion of BclXL into DMPC/DHPC (1,2-dimyristoyl-sn-glycero-3-phosphocholine/1

136 t solution but can be directly purified into DMPC/Chaps.

137 Measurements of WALP19 in the ether-linked DMPC analogue ditetradecylphosphatidylcholine (missing t

138 different ratios of the zwitterionic lipid (DMPC, dimyristoyl phosphatidylcholine; DOPC, dioleoyl ph

139 In the mixed DMPC/DMPG bilayers, maculatin 1.1 induced DMPG phase sep

140 pid, these domains can convert multilamellar DMPC vesicles into discoidal-shaped particles.

141 h an enhanced effect relative to the neutral DMPC bilayers.

142 hatidylcholine (egg PC) and is therefore not DMPC-dependent.

143 rent concentration on the phase behaviour of DMPC (1,2-dimyristoyl-sn-glycero-3-phosphocholine) multi

144 Here, supported phospholipid bilayers of DMPC (1,2-dimyristoyl-sn-glycero-3-phosphocholine) were

145 at the segmental order parameters (S(CD)) of DMPC approach very large values of approximately 0.35 in

146 ar vesicles indicate that the acyl chains of DMPC are highly disordered in the presence of the peptid

147 led that the volume expansion coefficient of DMPC and DMPC/Cholesterol samples with 13 and 25 mol% ch

148 econstituted vesicle dispersions composed of DMPC, C20BAS/E. coli polar lipid, C20BAS/POPC, C32phytBA

149 ptide bound to membrane bicelles composed of DMPC, DMPG, and DHPC, and compare it to the location of

150 in 1.2 in charged lipid bilayers composed of DMPC/DMPG.

151 rmotropic phase transition of MLVs formed of DMPC and the DMPC/DMPG (7:3) mixture suggests specific l

152 yer adjacent to the hydrophilic headgroup of DMPC.

153 of peptides interact with the headgroups of DMPC and DMPG bilayers.

154 Specifically, an aqueous phase incubation of DMPC vesicles with purified apolipoprotein A-I results i

155 simulations for several bilayer mixtures of DMPC and cholesterol.

156 Adding 1.0 mg/mL of DMPC to the drinking water of 10-month-old apoE-null fem

157 ave no significant effect on the ordering of DMPC acyl chains.

158 -fusion inhibitor, decreased the ordering of DMPC headgroups, whereas arachidonic acid, a membrane-fu

159 e-fusion promoter, increased the ordering of DMPC headgroups.

160 o indicate that increasing the percentage of DMPC leads to a marked slowing of CNTP diffusion.

161 of DOPC lipid with a variable percentage of DMPC lipid added to it.

162 erface (for example, >43% in the presence of DMPC).

163 in the bicelle size and, thus, proportion of DMPC bilayer present.

164 c ring system with increasing proportions of DMPC in the bicelle preparation.

165 The rate of DMPC microsolubilization by apoA-I is highly dependent u

166 able basis for their effects on the rates of DMPC microsolubilization.

167 to be modulated by the q value, the ratio of DMPC to DHPC, which reflects changes in the bicelle size

168 ated with a slower rate of solubilization of DMPC vesicles by apoE4-mut1 and reduced binding of the p

169 concentration, and the lipid phase state of DMPC, the kinetics varied over 3 orders of magnitude.

170 this temperature becomes similar to that of DMPC.

171 eract differently with AQP0 than do those of DMPC, but the acyl chains in the EPL and DMPC bilayers o

172 complexes rising more steeply than those of DMPC/DMPG-peptide complexes.

173 The phase transition of DMPC shifted from 23.4 degrees C toward lower temperatur

174 nergy of 220 kJ/mol for the translocation of DMPC, DPPC, and DSPC was determined.

175 rbidity clearance of unilamellar vesicles of DMPC, is faster at acidic pH values and consistent with

176 a-helical content in solution (0-48%) and on DMPC (40-75%).

177 otein secondary structure in solution and on DMPC correlates strongly with the maximal temperature of

178 roteins with higher alpha-helical content on DMPC may form more stable complexes.

179 Furthermore, 2H NMR experiments on DMPC-d54 multilamellar vesicles indicate that the acyl c

180 ponent (either DDPC in DDPC/DMPC mixtures or DMPC in DMPC/DSPC mixtures) extending 2-3 nm away from t

181 ituted into a TFE/H(2)O mixture or a POPC or DMPC bilayer were estimated to be 10.6 +/- 0.5, 16.8 +/-

182 form of small unilamellar vesicles (SUVs) or DMPC-NP-SLBs with excess DMPC-SUVs to support colloidal

183 Solid-state (15)N-NMR in oriented DMPC bilayers yielded a helix tilt angle of tau = 14 deg

184 labeled peptides was carried out in oriented DMPC bilayers.

185 nvironment, namely, macroscopically oriented DMPC:DHPC bicelles.

186 ep and immediate weakening, whereas the P294-DMPC binding was slightly strengthened at pH 3.7 and the

187 As the pH was lowered, P326-DMPC binding had a steep and immediate weakening, wherea

188 egrees C did not cause colour change in PCDA/DMPC vesicles for a period of up to 60days of storage.

189 In fluid-phase DMPC bilayer systems, the peptides interacted primarily

190 e in membrane fluidity between the gel phase DMPC and the liquid crystal phase POPC for peptide-membr

191 -disruptive effect is enhanced for gel phase DMPC membranes.

192 tron density profiles with that of gel phase DMPC provides areas per lipid A, 60.6 +/- 0.5 A(2) for D

193 In gel-phase DMPC vesicles, the native peptide disrupted the bilayer

194 imyristoyl-sn-glycero-3-phosphatidylcholine (DMPC) bilayers at various temperatures.

195 imyristoyl-sn-glycero-3-phosphatidylcholine (DMPC).

196 imyristoyl-sn-glycero-3-phosphatidylcholine (DMPC)/1,2-dimyristoyl-sn-glycero-3-phosphatidylglycerol

197 icelle or a dimyristoyl phosphatidylcholine (DMPC) bilayer, have been used to explore the conformatio

198 (AQP0) with dimyristoyl phosphatidylcholine (DMPC) lipids.

199 plexes with dimyristoyl phosphatidylcholine (DMPC) that resemble nascent HDL were analyzed by density

200 binding to dimyristoyl phosphatidylcholine (DMPC) vesicles and to triglyceride (TG)-rich emulsion pa

201 apoC-1) and dimyristoyl phosphatidylcholine (DMPC).

202 an explicit dimyristoyl-phosphatidylcholine (DMPC) lipid bilayer.

203 hospholipid dimyristoyl-phosphatidylcholine (DMPC) the two-state model was sufficient to account for

204 1)) and 1,2-dimyristoyl-phosphatidylcholine (DMPC-d(54)) at different temperatures demonstrates the i

205 yristoyl or dipalmitoyl phosphatidylcholine (DMPC or DPPC), the latter without or with cholesterol, w

206 myristoyl-sn-glycero-3-phosphatidylcholine] (DMPC) interface in the OH stretching mode region of wate

207 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) and 1,2-dihexanoyl-sn-glycero-3-phosphocholine (DH

208 ids dimyristoyl-sn-glycero-3-phosphocholine (DMPC) and 1,2-dihexanoyl-sn-glycero-3-phosphocholine (DH

209 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) and its mixtures with different amounts of cholest

210 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) and POPC/POPS 3:1 liposomes retain a bilayer macro

211 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) and the saponin glycyrrhizin in the presence of su

212 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) are investigated as constructs for removing PAHs f

213 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) are repeated in POPC.

214 h a 1,2-dimyristoylglycero-3-phosphocholine (DMPC) bilayer obtained from modeling and all-atom explic

215 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) bilayers in the presence of MSI-78 provides images

216 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) bilayers, the first equivalent of drug bound S31 i

217 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) liposomes were the model system chosen to mimic th

218 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) liposomes, suggesting that lateral gating of the B

219 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) vesicles and dodecylphosphocholine (DPC) micelles

220 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC)) and phosphatidylglycerols (PGs, such as 1,2-dimyr

221 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC), 1,2-dilauroyl-sn-glycero-3-phosphocholine (DLPC),

222 -dimyristoleoyl-sn-glycero-3-phosphocholine (DMPC), 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC),

223 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC), 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC

224 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC), 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC

225 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC).

226 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC).

227 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC)/1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC)

228 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC)/3-[(cholamidopropyl)dimethyl-ammonio]-1-propane su

229 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC:DSPC).

230 f 1,2-dimyristoyl-sn-glycero-phosphocholine, DMPC) and the bacterial (liposomes of 1,2-dimyristoyl-sn

231 out in explicit lipid bilayers (DEPC, POPC, DMPC, sphingomyelin), confirming the observed dependence

232 that decreasing bilayer thickness (DEPC-POPC-DMPC) led to an increase in the helix tilt angle from 10

233 These bicelles are thought to provide DMPC bilayer fragments with most DHPC capping the bilaye

234 of the bilayer is similar to that of a pure DMPC, there are localized perturbations.

235 thermodynamic quantities characterizing pure DMPC and DMPC/cholesterol mixtures, thus directly confir

236 r (GlyR) was achieved in low-q bicelles (q = DMPC/DHPC).

237 iscriminating between different modes of ras-DMPC interactions.

238 markedly increased in the mice that received DMPC.

239 dramatically improved in the mice receiving DMPC, and there was a significant reduction in aortic le

240 he electrochemical detection of single redox DMPC liposome collisions at polarized UMEs was investiga

241 current spikes corresponding to single redox DMPC liposome collisions with K(3)Fe(CN)(6)/K(4)Fe(CN)(6

242 electrochemical detection of synthetic redox DMPC (1,2-dimyristoyl-sn-glycero-3-phosphocholine) lipos

243 pid bilayers (unsaturated POPC and saturated DMPC) is explored through molecular dynamics (MD) simula

244 25-50% anionic lipids, and in both saturated DMPC/DMPG (1,2-dimyristoyl-sn-glycero-3-phosphatidylchlo

245 e simulated an excess proton near a solvated DMPC bilayer at 323 K, using a recently developed method

246 lateral mobility of globular actin-supported DMPC (1,2-dimyristoyl-sn-glycero-3-phosphocholine) bilay

247 observed magainin interacting with synthetic DMPC/DMPG membranes.

248 eraction with the protein or by altering the DMPC/Chaps bilayer properties within the bicelle.

249 ns between the H-ras membrane anchor and the DMPC bilayer are investigated in detail.

250 teraction between these Trp residues and the DMPC interfacial region.

251 se transition of MLVs formed of DMPC and the DMPC/DMPG (7:3) mixture suggests specific lipid-peptide

252 form is just long enough to wrap around the DMPC bilayer disk once.

253 ne tension of approximately 10-30 pN for the DMPC edge, in qualitative agreement with experimental es

254 r, transition peak has been observed for the DMPC: cholesterol mixtures suggest that a separate chole

255 In the DMPC bilayer, the hydrophobic component dominates, regar

256 reduction in aortic lesions (P=0.021) in the DMPC mice but not in those receiving lecithin.

257 )) are 0.3 and 0.73 G for the peptide in the DMPC or POPC bilayer environment, respectively.

258 e inclusion of Chaps rather than DHPC in the DMPC/Chaps bicelles, however, imparts the greatest stabi

259 This suggests that it is not just the DMPC bilayer fragment in the bicelles that stabilises th

260 volves two factors: 1) calcium ions make the DMPC bilayer partially cationic and thus attractive to t

261 cal thinning and 2 A average thinning of the DMPC (1,2-dimyristoyl-sn-glycero-3-phosphochloline)/DMPG

262 phodiester groups in the two leaflets of the DMPC and EPL bilayers is almost identical.

263 distinct alterations in the structure of the DMPC bilayer than the deprotonated/ionized form, conside

264 ich matches the hydrophobic thickness of the DMPC bilayer.

265 Using kinetic analysis of the DMPC clearance assay, we show that the identified phosph

266 Interestingly, at Tc = 24 degrees C of the DMPC gel-to-liquid crystal transition, the clearance rat

267 recorded showed that the permeability of the DMPC lipid membrane (tuned by addition of Triton X-100 s

268 In addition, the conformation of the DMPC sn-3 chain in 4F.DMPC complex is different than in

269 his cholesterol concentration is reached the DMPC-rich domain disappears.

270 According to turbidimetric titrations, the DMPC/apo A-II stoichiometry is 65/1 (moles to moles).

271 reduces the affinity of Abeta binding to the DMPC bilayer by disrupting favorable intrapeptide intera

272 ium strengthens Abeta peptide binding to the DMPC bilayer by enhancing electrostatic interactions bet

273 , oxidation "polarizes" Abeta binding to the DMPC bilayer by strengthening the interactions of the C-

274 te cholesterol rich domain coexists with the DMPC rich domain.

275 curring Abeta fragment Abeta25-35 within the DMPC lipid bilayer.

276 investigated using thicker POPC and thinner DMPC bilayers.

277 peptide is more heterogeneous in the thinner DMPC bilayer than in the thicker POPC bilayer.

278 model in which apo A-I and apo A-II bind to DMPC via surface defects that disappear at 20 mol % FC.

279 lipid-protein domains upon apoA-I binding to DMPC LUVs.

280 scopy demonstrated that the peptide binds to DMPC with a high affinity to form at least two sizes of

281 When bound to DMPC, [1-44]apoA-I has approximately 60% helical structu

282 ises from the near-bulk water nonadjacent to DMPC.

283 g of the drug molecules in optically trapped DMPC vesicles, the membrane permeability and partitionin

284 inosa demonstrate viability and growth using DMPC-NP-SLBs and DMPC-SUVs, with and without BaP, as the

285 not possible with the previous method using DMPC vesicles.

286 We previously reported on using DMPC (dimyristoylphosphatidylcholine) vesicles for reali

287 We propose that apoA-I binds with DMPC LUVs to form small lipid-protein domains on the LUV

288 ion of residues in the catalytic domain with DMPC phosphates.

289 ed amantadine, an antiinfluenza A drug, with DMPC bilayers were investigated by solid-state NMR and b

290 The reaction kinetics of apoA-I with DMPC LUVs was monitored by fluorescence resonance energy

291 ow that LL7-27 is completely integrated with DMPC/DMPG (3:1) liposomes, but induces peptide-rich and

292 LUV and a half-life time around 10 min with DMPC SUV.

293 teractions of single Nile Red molecules with DMPC and SOPC lipid bilayers were studied by single mole

294 , apo A-II, like apo A-I, reacts poorly with DMPC containing >/=20 mol % FC.

295 ion of gramicidin D at a 1:20 mol ratio with DMPC results in the formation of protein-lipid hydrogen

296 yl-sn-glycero-3-phosphocholine (DHPC), with [DMPC]/[DHPC] = 2.5, in 10% lipid/aqueous buffer at 25 de

297 elles, and TM2 was disordered in zwiterionic DMPC but was alpha-helical in negatively charged DMPC/DM

298 showed much weaker affinity for zwitterionic DMPC, but had moderate binding affinity to negatively ch

299 eta10-40 peptide binding to the zwitterionic DMPC bilayer.

300 negatively charged DMPG than to zwitterionic DMPC.