ライフサイエンスコーパス: DMR

1 DMR analysis identified 47 regions associated with the P

2 DMR detection is then carried out via a Wald test proced

3 DMRs found overlapping CpG islands and exons of imprinte

4 DMRs included six nonoverlapping DMRs (three in the Neth

5 DMRs located within intergenic regions were heavily enri

6 -0.0013; 95% CI: -0.0023, -0.0003, p = 0.01) DMR methylation, but primarily in females, (beta = -0.00

7 Of the 12 DMRs related to PTSD symptom reduction, consistent prosp

8 We validated 13/15 DMRs by targeted analysis of methylation.

9 Comb-p detected between 4 and 15 DMRs for each PFAS.

10 macrophages emerged in VWAT along with 1520 DMRs (P < 0.0001), associated with 693 genes.

11 for asthma (285-CpGs), FeNO (8,372-CpGs; 191-DMRs), total IgE (3-CpGs; 3-DMRs), environment IgE (17-C

12 Rs of 648 genes were hypermethylated and 274 DMRs of 336 genes were hypomethylated in trained group c

13 , vitamin B-12 intake was associated with 29 DMRs annotated to 48 genes, of which the most significan

14 (8,372-CpGs; 191-DMRs), total IgE (3-CpGs; 3-DMRs), environment IgE (17-CpGs; 4-DMRs), allergic asthm

15 thylated region (DMR) approach, we found 315 DMRs between groups, including 28 regions encompassing 6

16 Furthermore, we identified that 335 DMR-associated genes (DMGs), such as NAC016 and SEN1, ar

17 Furthermore, a subset of 34 DMRs related to impaired oxidative stress, DNA repair, a

18 ribed in previous studies, in addition to 34 DMRs not previously reported.

19 We replicated 3/4 DMRs identified in our genome-wide screen in a different

20 3-CpGs; 3-DMRs), environment IgE (17-CpGs; 4-DMRs), allergic asthma (1,235-CpGs; 7-DMRs) and bronchod

21 We discovered that 440 DMRs of 648 genes were hypermethylated and 274 DMRs of 3

22 pGs; 4-DMRs), allergic asthma (1,235-CpGs; 7-DMRs) and bronchodilator response (130-CpGs).

23 To examine biological themes, we selected 70 DMRs with false discovery rate of <0.1.

24 However, 14, 48, 183, 8, and 71 DMRs independently associated with aircraft, railway, an

25 Using this approach we identified 77 DMRs, including nearly all those described in previous s

26 We identified 25,820 DMRs in islets from individuals with T2D.

27 anscription elongation factor AFF3 between a DMR and an enhancer.

28 These include a DMR at TUBGCP5 within the recurrent 15q11.2 microdeletio

29 ethylome and returning potentially novel age DMRs, in addition to replicating several loci implicated

30 mbined into "allostatic load") and agnostic (DMR-based) pathway enrichment tests, and replicated prev

31 eriments in which accuracy of mC calling and DMR detection is evaluated on simulated data with variou

32 texts, read qualities, sequencing depths and DMR lengths, as well as on real data from a wide range o

33 ns between methylation at candidate DMPs and DMR sites and the following outcomes: newborn weight, ad

34 he genes identified in both the CpG site and DMR approaches were located in the MHC region on chromos

35 Several differentially methylated CpGs and DMRs associated with prenatal PM exposure were identifie

36 y methylated positions and regions (DMPs and DMRs) were identified through linear regression analysis

37 ntified and replicated thousands of DMPs and DMRs.

38 a new software package for detecting mCs and DMRs from bisulfite sequencing data.

39 We replicate the top DMP (RPS6KA2) and DMRs (VMP1, ITGB2 and TXK) in an independent cohort.

40 No expression changes were detected in any DMRs.

41 ASD DMRs at CYP2E1 and IRS2 reached genome-wide significance

42 These ASD DMRs were significantly enriched at promoters, mapped to

43 stricted ASM, and among them are 188 hap-ASM DMRs and 933 mQTLs located near GWAS signals for immune

44 ng sites were over-represented among hap-ASM DMRs and mQTLs, and analysis of the human data, suppleme

45 The most significant folate-associated DMR was a 400-base pair (bp) spanning region annotated t

46 on changes, especially in non-CGI-associated DMRs.

47 ed ABBA to identify >1000 disease-associated DMRs.

48 egional analysis showed 74 folate-associated DMRs, of which 73 were negatively associated with folate

49 ne marks were enriched in the T2D-associated DMRs.

50 For two trait-associated DMRs, vgt1-DMR and tb1-DMR, HiChIP data indicate that th

51 prognostic/therapeutic implications of AF at DMR diagnosis and long-term.

52 AF is a frequent occurrence at DMR diagnosis.

53 ethylation in peripheral blood leukocytes at DMRs of 22 human imprinted genes.

54 e define patterns of epigenetic variation at DMRs, identifying rare individuals with global gain or l

55 Strong associations between DMRs and the expression of many genes are identified in

56 atments identified some associations between DMRs, genes and transposons.

57 indicate that the interactive loops between DMRs and respective downstream genes are present in B73,

58 ARK2, PID1, SLC2A2, and SOCS2, that had both DMRs and significant expression changes in T2D islets.

59 ic DMRs (t-DMRs) and cancer-specific DMRs (c-DMRs), and 5hmC is negatively correlated with methylatio

60 nces in both CpG and non-CpG methylation (CG-DMRs and CH-DMRs) only in neuronal cells across brain re

61 These CG-DMRs comprise ~12 Mb of the genome that is highly enrich

62 ith differential gene expression, whereas CG-DMRs were consistent with chromatin accessibility and en

63 CpG and non-CpG methylation (CG-DMRs and CH-DMRs) only in neuronal cells across brain regions.

64 Neuronal CH-DMRs were highly associated with differential gene expre

65 s, resulting in the discovery of 1966 common DMRs and 1754 rare DMRs.

66 Altogether, BRCA1 and CRISP2 DMRs hold promise as novel blood surrogate markers for e

67 ntegrated network analysis, BRCA1 and CRISP2 DMRs were identified as most central disease-associated

68 Furthermore, our method can detect DMRs from a single pair of samples and can also incorpor

69 samples; and (iii) the capability to detect DMRs from a single pair of samples is demanded.

70 shows that ABBA has greater power to detect DMRs than existing methods, providing an accurate identi

71 l), a novel Bayesian framework for detecting DMRs from methylation array data.

72 tatistical method, DSS-single, for detecting DMRs from WGBS data without replicates.

73 Discovered DMRs annotated to genes implicated in allergic asthma, T

74 rentially methylated positions/regions (DMPs/DMRs), across multiple pairwise comparisons.

75 We present DMRMark (DMR detection based on non-homogeneous hidden Markov mod

76 al aspects that we can improve over existing DMR detection (i) methylation statuses of nearby CpG sit

77 In contrast, very few DMRs distinguished regions of the cortex, limbic system

78 terns of DNA methylation in regions flanking DMRs reveals a distinct subset of DMRs.

79 Few tools exist for DMR identification from this type of data, but there is

80 ol for mC calling, and a novel framework for DMR detection based on hidden Markov models (HMMs).

81 fter comprehensive adjustment, including for DMR severity (adjusted hazard ratio [HR]: 1.05 [95% conf

82 We propose a novel method for DMR identification that detects the region boundaries ac

83 ve been proposed for mC calling, methods for DMR detection have been largely limited.

84 ysis results reveals a strong enrichment for DMRs in T2D-susceptibility loci.

85 that AFF3 can specifically bind both gametic DMRs (gDMRs) and enhancers within imprinted loci in an a

86 blishment of methylation at maternal gametic DMRs.

87 e of BAC on mammography using the WIPRO GE - DMR PLUS mammography unit.

88 There are a large number of germline DMRs that have not yet been associated with imprinting,

89 tween the <40 y group and the >/=40 y group (DMRs, 21% and 22%, respectively; P = 1).

90 ially methylated region upstream of H19 (H19-DMR), serving as the imprinting control region, determin

91 ion of the maternal but not the paternal H19-DMR reduces adult haematopoietic stem cell quiescence, a

92 We found that heavy infection (i.e., high DMR) resulted in reduced growth during all four measurem

93 Each gene had high DMR methylation and lower expression, which were associa

94 Human DMRs were enriched for specific histone modifications an

95 on factor binding sites located within human DMRs, suggesting that alteration of regulatory motifs un

96 riod was associated with higher PLAGL1/HYMAI DMR methylation regardless of sex (beta = 0.0075; 95% CI

97 Hypermethylated DMRs were more likely to overlap with CpG islands and sh

98 Hypomethylated DMRs were more likely to be in regions associated with p

99 esent a novel program, metilene, to identify DMRs within whole-genome and targeted data with unrivale

100 powerful, and accurate tool for identifying DMRs.

101 19 different chromosomes, defining imprinted DMRs as sites where the maternal and paternal methylatio

102 me-wide approach to identify novel imprinted DMRs in the human placenta and investigated the dynamics

103 Forty-three known and 101 novel imprinted DMRs were identified in the human placenta by comparing

104 investigated the dynamics of these imprinted DMRs during development in somatic and extraembryonic ti

105 t assays (two CpG islands and six imprinting DMRs) and demonstrated its benefits, including the abili

106 No significant difference in DMRs was observed between the <40 y group and the >/=40

107 esting the presence of unique information in DMRs.

108 Inter-individual DMRs were readily detectable in these regions.

109 tionally, the ability to detect short length DMRs is necessary as biologically relevant signal may oc

110 ene 3 differentially methylated region (MEG3-DMR), which acts as a cis-regulatory element for 14q32 m

111 5-Aza-dC activated demethylation of the MEG3-DMR and expression of 14q32 miRNAs, which suppressed adh

112 Cancer cells with MEG3-DMR hypomethylation exhibited constitutive expression of

113 group comparisons, MethylAction detects more DMRs with strong differential methylation measurements c

114 es of neonatal keratinocytes share many more DMRs with adult breast luminal and myoepithelial cells t

115 Of nine DMRs that could be queried in a reduced representation b

116 DMRs included six nonoverlapping DMRs (three in the Netherlands Twin Register, three in t

117 rinted expression associated with nine novel DMRs.

118 Seventy-two novel DMRs showed a pattern consistent with placental-specific

119 The frequent left atrial enlargement of DMR as measured by LAVI in routine practice displays, ov

120 From these, we identified a network of DMR-associated genes involved in glutamatergic synaptic

121 A number of DMR associated genes were identified and previously show

122 th older age and more severe presentation of DMR, it is independently associated with excess mortalit

123 d across the entire population regardless of DMR level, and (b) both moderate and heavy infections re

124 ct locations of DMRs and better agreement of DMRs with gene expression and DNase I hypersensitivity.

125 there is little evidence for association of DMRs with genes that show quantitative differences in ge

126 nal statistical test allows the detection of DMRs in large methylation experiments with multiple grou

127 c islets, and to investigate the function of DMRs in islet biology.

128 ods, providing an accurate identification of DMRs in the large majority of simulated cases.

129 s insights into the origin and influences of DMRs in a crop species with a complex genome organizatio

130 he sequence specificity of DMRs, location of DMRs relative to genes and transposons, and patterns of

131 imates of mC levels, more exact locations of DMRs and better agreement of DMRs with gene expression a

132 ful in selecting the most robust patterns of DMRs.

133 racterization of the sequence specificity of DMRs, location of DMRs relative to genes and transposons

134 s flanking DMRs reveals a distinct subset of DMRs.

135 We identified one DMR on chromosome 11 (chr11:2,322,050-2,323,247), annota

136 Unlike existing methods, our DMR detection is achieved without predefined boundaries

137 To demonstrate further the utility of our DMR set, we use it to classify unknown samples and ident

138 Several of our DMRs are at genes with potential relevance for age-relat

139 P-DMRs located in INSR and CPT1A have enhancer activity in

140 ociated differentially methylated regions (P-DMRs) is lacking in humans.

141 on and further exploratory analysis of six P-DMRs highlight the critical role of gestational timing.

142 We show that P-DMRs preferentially occur at regulatory regions, are cha

143 restingly, differential methylation of the P-DMRs extends along pathways related to growth and metabo

144 sociated with a significant decrease in PEG3 DMR methylation (beta = -0.0014; 95% CI: -0.0023, -0.000

145 blocker profiling showed that the pinacidil DMR is due to the activation of SUR2/Kir6.2 KATP channel

146 cted a comprehensive evaluation of 4 popular DMR analysis tools under 60 different parameter settings

147 , FAM92A1, MIR155HG, and VWA8) with promoter DMRs and expression associated with overall survival (OS

148 Genes with promoter DMRs and expression levels significantly associated with

149 discovery of 1966 common DMRs and 1754 rare DMRs.

150 is by comparing the distant metastasis rate (DMR) on initial (18)F-FDG PET/CT in a group of breast ca

151 The dwarf mistletoe rating (DMR), a measure of infection intensity, varied among ind

152 umors without distant metastatic recurrence (DMR) and metastases.

153 Dynamic mass redistribution (DMR) profiling resulted in a pharmacological activity ma

154 tically similar dynamic mass redistribution (DMR) signals in A431, A549, HT29 and HepG2C3A, but not i

155 referred to as dynamic mass redistribution (DMR).

156 revealed a differentially methylated region (DMR) adjacent to the distal PR-binding site (PRBS) 87 kb

157 Using a differentially-methylated region (DMR) approach, we found 315 DMRs between groups, includi

158 (CGI) or a Differentially Methylated Region (DMR), avoiding 'one-at-a-time' CpG calibration.

159 e upstream differentially methylated region (DMR), which also included the site motifs for the enhanc

160 entified a differentially methylated region, DMR-DLGAP2, associated with alcohol dependence.

161 Multiple differentially methylated regions (DMR) could be identified in atherosclerosis patients, re

162 lly methylated positions (DMPs) and regions (DMRs), and a pathway analysis was performed on the DMR a

163 lly methylated positions (DMPs) and regions (DMRs).

164 ly methylated CpGs (FDR < 0.05) and Regions (DMRs; >= 5-CpGs and FDR < 0.05) for asthma (285-CpGs), F

165 for differentially methylated gene regions (DMRs) using a methylated DNA immunoprecipitation on chip

166 and the DMRcate method to identify regions (DMRs) and conducted gene ontology enrichment analysis.

167 5 hap-ASM differentially methylated regions (DMRs) and 3,082 strong methylation quantitative trait lo

168 ificantly differentially methylated regions (DMRs) and 963 differentially methylated genes (DMGs) wer

169 that differentially DNA-methylated regions (DMRs) and enhancers are two major classes of cis-element

170 D-related differentially methylated regions (DMRs) and replicate the top signals in 42 unrelated T2D

171 ependent, differentially methylated regions (DMRs) are identical to the DMRs recently identified in u

172 usands of differentially methylated regions (DMRs) are identified population-wide that are correlated

173 s) and 10 differentially methylated regions (DMRs) associated with asthma severity.

174 dditional differentially methylated regions (DMRs) associated with hippocampal volume.

175 fied 1027 differentially methylated regions (DMRs) associated with parental THC exposure in F1 adults

176 dentified differentially methylated regions (DMRs) associated with prognostic mutations in older (>/=

177 -specific differentially methylated regions (DMRs) between any two genotypes.

178 to detect differentially methylated regions (DMRs) between paired samples.

179 al of 400 differentially methylated regions (DMRs) discriminated placentas stored from children later

180 g control differentially methylated regions (DMRs) established in the germline.

181 to detect differentially methylated regions (DMRs) from whole-genome bisulfite sequencing (WGBS).

182 Of 811 differentially methylated regions (DMRs) identified in ACF, 537 (66%) were hypermethylated

183 ith known differentially methylated regions (DMRs) in colon tumors.

184 or common differentially methylated regions (DMRs) in CRC.

185 identify differentially methylated regions (DMRs) in diabetic islets, and to investigate the functio

186 Differentially methylated regions (DMRs) in each methylation context showed very distinct m

187 imprinted differentially methylated regions (DMRs) in gametes or their maintenance in early embryogen

188 dentified differentially methylated regions (DMRs) in HLA-DRB1 and RNF39.

189 ndreds of differentially methylated regions (DMRs) in humans compared to non-human primates and estim

190 sites and differentially methylated regions (DMRs) in relation to 1-y average aircraft, railway, and

191 ssociated differentially methylated regions (DMRs) in the epigenome.

192 ion at 12 differentially methylated regions (DMRs) in the genes: APOB, MUC4, EDN2, ZFP57, GPX6, CFAP4

193 identify differentially methylated regions (DMRs) instead of DMPs.

194 ection of differentially methylated regions (DMRs) is a necessary prerequisite for characterizing dif

195 ection of differentially methylated regions (DMRs) is enthralling for many disease studies.

196 ified 167 differentially methylated regions (DMRs) of DNA at baseline that distinguished responders f

197 -specific differentially methylated regions (DMRs) often overlap tissue-specific distal cis-regulator

198 ssociated differentially methylated regions (DMRs) passed Bonferroni correction (P-value < 1.15 x 10(

199 entifying differentially methylated regions (DMRs) remains a challenging task because of the complexi

200 s and 119 differentially methylated regions (DMRs) significantly associated with Braak stage.

201 everaging differentially methylated regions (DMRs) specific to cell type, identified from DNAm measur

202 erlapping differentially methylated regions (DMRs) such as hypermethylated CpG islands, which may acc

203 an 16,000 differentially methylated regions (DMRs) that are distributed across the 10 maize chromosom

204 ulated by differentially methylated regions (DMRs) that are established in the germline and maintaine

205 alter the differentially methylated regions (DMRs) that control the monoallelic expression of imprint

206 to detect differentially methylated regions (DMRs) that uses combined signals from differential methy

207 ified 557 differentially methylated regions (DMRs) that were overrepresented ([Formula: see text]) in

208 gnificant differentially methylated regions (DMRs) using a bump hunting approach and a permutation-ba

209 -specific differentially methylated regions (DMRs) were found in genes involved in metabolic pathways

210 nd 20 556 differentially methylated regions (DMRs) were identified by comparing the methylomes of dml

211 0.05 and differentially methylated regions (DMRs) were identified using comb-p (Sidak-adjusted p < 0

212 to reveal differentially methylated regions (DMRs) with context-specific functional correlations.

213 ontaining differentially methylated regions (DMRs) with negative correlation between their expression

214 level of differentially methylated regions (DMRs), and bootstrapping determines false discovery rate

215 cohort of differentially methylated regions (DMRs), most of which gain DNA methylation between the ea

216 Ps) and 5 differentially methylated regions (DMRs), which we study in detail using whole genome bisul

217 based on differentially methylated regions (DMRs).

218 esence of differentially methylated regions (DMRs).

219 er 16 000 differentially methylated regions (DMRs).

220 entifying differentially methylated regions (DMRs).

221 nother on differentially methylated regions (DMRs).

222 ied 2,130 differentially methylated regions (DMRs; <5% false discovery rate), of which 738 are associ

223 e-specific differential methylation regions (DMRs) overlapping enhancers, including super-enhancers (

224 ure of differential DNA methylation regions (DMRs) was identified to be associated with male idiopath

225 nificant differentially methylation regions (DMRs) were identified in the Netherlands Twin Register,

226 tified differential DNA methylation regions (DMRs).

227 plicating degenerative mitral regurgitation (DMR) a debated indication for surgery.

228 tional or degenerative mitral regurgitation (DMR) at high surgical risk.

229 equent in degenerative mitral regurgitation (DMR), but its link to outcomes remains unproven in routi

230 or severe degenerative mitral regurgitation (DMR).

231 method identified additional cancer-related DMRs that were missed by methods using one type of signa

232 eam that retrospectively evaluated high-risk DMR patients enrolled in the EVEREST (Endovascular Valve

233 A total of 141 high-risk DMR patients were consecutively enrolled; 127 of these p

234 A prohibitive-risk DMR cohort was identified by a multidisciplinary heart t

235 tral valve repair (TMVR) in prohibitive-risk DMR patients have not been previously reported.

236 , LAVI measurement should be part of routine DMR evaluation and the clinical decision-making process.

237 Hypomethylated SE-DMRs are in proximity to genes with SE relevant function

238 ify SE differentially methylated regions (SE-DMRs).

239 We also identified several DMRs associated with either prenatal [Formula: see text]

240 l regurgitation (MR) in patients with severe DMR at prohibitive surgical risk undergoing TMVR.

241 The most significant DMR identified is located on the MAMSTR gene, which enco

242 eQTLs where a methylation change at a single DMR is associated with transcriptional changes in a subs

243 e-specific DMRs (t-DMRs) and cancer-specific DMRs (c-DMRs), and 5hmC is negatively correlated with me

244 fy thousands of developmental stage-specific DMRs (dsDMRs) across zebrafish developmental stages.

245 gnificantly enriched in both tissue-specific DMRs (t-DMRs) and cancer-specific DMRs (c-DMRs), and 5hm

246 ised methods for use when cell-type specific DMRs are not available, allowing scientists to estimate

247 tly enriched in both tissue-specific DMRs (t-DMRs) and cancer-specific DMRs (c-DMRs), and 5hmC is neg

248 two trait-associated DMRs, vgt1-DMR and tb1-DMR, HiChIP data indicate that the interactive loops bet

249 ] exposure, of which two [Formula: see text] DMRs, including H19 and MARCH11, replicated in newborns.

250 re, gene ontology analysis demonstrated that DMRs associated with promoters were enriched for genes i

251 ted genetic variation provided evidence that DMRs can occur without local sequence variation, but the

252 two independent BRCA data sets suggest that DMRs detected based on DV are reproducible.

253 The DMR at HTR2A is located within the bounds of a haplotype

254 The DMR genes were enriched in neuronal related pathways.

255 The DMR was not significantly higher in younger breast cance

256 G PET/CT examinations were reviewed, and the DMR was recorded for each clinical stage subgroup (stage

257 Methylation at the DMR-DLGAP2 regulated expression of DLGAP2 in vitro, and

258 he bounds of a haplotype block; however, the DMR remained significant after accounting for SNPs in th

259 otide polymorphisms found within or near the DMR.

260 cytosine guanine dinucleotide status of the DMR correlated with expression of the miRNAs following a

261 The majority of the DMR genes in the CHH context were transcriptionally down

262 Hypermethylation of the DMR inhibited recruitment of PR to the adjacent PRBS.

263 and a pathway analysis was performed on the DMR annotated genes.

264 Luciferase assays indicated that the DMR and distal PRBS constitute a novel RANKL distal regu

265 Pathway deconvolution revealed that the DMR of epinephrine is originated mostly from the remodel

266 h both ASD diagnosis and genotype within the DMR.

267 The DMRs identified in this study represent suggestive evide

268 The DMRs in patients not selected for age were 8% for stage

269 how that AG-haESCs carrying deletions in the DMRs (differentially DNA methylated regions) controlling

270 -specific DNA methylation differences in the DMRs of PEG3, IGF2/H19, and PLAGL1/HYMAI in adulthood.

271 genetic markers reveals that over 60% of the DMRs are not tagged by SNPs, suggesting the presence of

272 sociation scan found that nearly half of the DMRs with common variation are significantly associated

273 analysis results, including the size of the DMRs, overlap between the methods and execution time.

274 thylated regions (DMRs) are identical to the DMRs recently identified in uniparental ESCs.

275 These DMRs are enriched at progesterone-responsive gene loci t

276 These DMRs cover loci with known islet function, e.g., PDX1, T

277 These DMRs fell predominantly within introns, exons, and inter

278 These DMRs were primarily localized to nonpromoter regions and

279 Interestingly, these DMRs overlapped with 1,145 known tumor suppressor genes.

280 a substantial number of genes; four of these DMRs are near transcription factors (castor zinc finger

281 More than half of these DMRs have cell type-restricted ASM, and among them are 1

282 Investigation of these DMRs revealed differential DNA methylation localized to

283 The methylation level for each of these DMRs was also assayed in 31 additional maize or teosinte

284 Of these DMRs, 92% were associated with methylation quantitative

285 Strikingly, these DMRs exhibited polymorphic imprinted methylation between

286 ctive cohort, we then examined whether these DMRs were also relevant for the development of deploymen

287 We identified three DMRs at HTR2A, SLC17A9 and HDAC4 that were consistent ac

288 Mortality rates were positively related to DMR, but only during the warm and dry measurement interv

289 Among genes implicated by the top DMRs were protocadherins, homeobox genes, MAPKs and ryan

290 that use only one type of signals when true DMRs have both.

291 For two trait-associated DMRs, vgt1-DMR and tb1-DMR, HiChIP data indicate that the interacti

292 he current study also identified genome-wide DMRs that were associated with the patients that were re

293 , multicenter, international experience with DMR due to flail leaflets echocardiographically diagnose

294 rdiologists is associated independently with DMR survival.

295 In subjects with DMR, all MV annular geometry-defining values were not si

296 ences in gene expression are associated with DMRs, and there is little evidence for association of DM

297 that only show significant associations with DMRs and not with SNPs.

298 methylation at IRS2 was unaffected by within DMR genotype but modified by preconceptional maternal pr

299 Methylation within DMR-DLGAP2 was found to be genotype-dependent, allele-sp

300 Patients without DMR had higher degrees of clustering between tumor cells