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1 t mediates stable binding to a non-canonical DNA motif.
2 ated separately through a conserved upstream DNA motif.
3 modular domains in a 42-base single-stranded DNA motif.
4 in reduced affinity of LOB for the consensus DNA motif.
5 domain of AtERF100 in complex with a GCC box DNA motif.
6 their DNA binding domains and bind a common DNA motif.
7 ing a protein (URE3-BP) that recognized this DNA motif.
8 ected to test the recognition ability of the DNA motif.
9 methylation at loci with a highly conserved DNA motif.
10 s contained the canonical RBP-Jkappa-binding DNA motif.
11 transcription, regardless of its recognition DNA motif.
12 tiation genes that it controls at a CCNNAGGC DNA motif.
13 th two affinity ligands each conjugated to a DNA motif.
14 of the FtsK-orienting polar sequence (KOPS) DNA motifs.
15 n forms homodimers that bind canonical G-box DNA motifs.
16 exposure, thereby distinguishing particular DNA motifs.
17 ional regulators recognize and bind specific DNA motifs.
18 t are programmable for a large repertoire of DNA motifs.
19 lie common functional roles in other RNA and DNA motifs.
20 ining different approaches to discover novel DNA motifs.
21 binations are enriched for different sets of DNA motifs.
22 members of the same subset and bind-specific DNA motifs.
23 b upstream that contains cytokine-responsive DNA motifs.
24 including cell wall components and specific DNA motifs.
25 both ChIP-exo tag distribution patterns and DNA motifs.
26 of VDR.retinoid X receptor-alpha to discrete DNA motifs.
27 roplast DNA, and 15% to the seven repetitive DNA motifs.
28 mmon Pbx1 or E2a-Pbx1 partner bind different DNA motifs.
29 HLH-zip region and recognize the same CACGTG DNA motifs.
30 rs and their corresponding sequence-specific DNA motifs.
31 insertions and deletions (indels), and novel DNA motifs.
32 letely lacked binding ability at its cognate DNA motifs.
33 ery and performance evaluation on methylated DNA motifs.
34 red regions bind synergistically to adjacent DNA motifs.
35 attenuated the latter's binding to promoter DNA motifs.
36 s involving known architectural proteins and DNA motifs.
37 ubiquitously expressed, and recognize G-rich DNA motifs.
38 dification and DNA methylation patterns from DNA motifs.
39 ion of most abundant double-stranded DNA (ds-DNA) motifs.
40 ents, and the extent of their hard-wiring by DNA motifs; (3) the potential to predict gene expression
41 graphic analysis shows that a hexanucleotide DNA motif (5'-TCGGAT-3') of the aptamer fits into a posi
42 Mutations of Ets or E-box sites in either DNA motif abolished the activation and reduced or elimin
43 of dot-blot hybridizations, seven repetitive DNA motifs accounted for >13% (194 kb) of the cucumber m
44 sequences, exemplified by G quadruplex and H-DNA motifs, across the genome in both avian and human ce
48 peptides encoded by a 'synthetic degenerate' DNA motif and fused to Maltose Binding Protein (MBP).
50 s were significantly enriched in the AATAATD DNA motif and specific chromatin contexts, including H3K
52 synthesis to identify candidate NiaR-binding DNA motifs and assess the NiaR regulon content in these
53 mics approach to infer candidate Rex-binding DNA motifs and assess the Rex regulon content in 119 gen
54 ow that recurrent neural networks trained on DNA motifs and basic phenotype data can reach 70% attrib
55 ies, TF family members often bind to similar DNA motifs and can confound sequence-based approaches to
56 ically identify 194 nonredundant palindromic DNA motifs and corresponding regulons in S. oneidensis.
58 ew analysis tools enable users to search for DNA motifs and define genes based on their genomic coloc
59 the target molecule triggers assembly of the DNA motifs and initiates the subsequent DNA strand displ
61 nalis genes was searched for overrepresented DNA motifs and known eukaryotic core promoter elements.
62 and a data yielded all of the four relevant DNA motifs and most of the known a- and alpha-specific g
63 comparative genomics approach, we identified DNA motifs and reconstructed regulons for 40 TunR family
64 parative genomics, we predicted SahR-binding DNA motifs and reconstructed SahR regulons in the genome
65 include transcription factors, their cognate DNA motifs and regulated genes/operons linked to the can
66 the behavior of single- and double-stranded DNA motifs and transitions between them, allowing us to
67 also distinct in their recognition of short DNA motifs and utilization of open DNA interaction inter
68 etail how CO positioning relates to genetic (DNA motifs) and epigenetic (chromatin structure) feature
69 d TRP120-bound sequences revealed a G+C-rich DNA motif, and recombinant TRP120 specifically bound syn
70 gical processes, share unique cis-regulatory DNA motifs, and are enriched for binding of specific tra
72 nding to noncoding variants, uncharacterized DNA motifs, and repetitive genomic elements has been tec
73 Metallic nanoparticles can be attached to DNA motifs, and the arrangement of these particles can b
74 These data support the hypothesis that CpG DNA motifs are a "danger signal" that activates protecti
76 ctions between Ap2 and Sp1 and their cognate DNA motifs are critical for basal transcription from the
77 with embryo cells indicate that the enriched DNA motifs are functional cis elements that regulate tra
80 n factor binding sites (TFBSs, also known as DNA motifs) are critical activities in gene transcriptio
81 ction in the gene, reveals that these (short DNA motifs) are more prevalent in exons that encode diso
83 Microsatellites--tandem repeats of short DNA motifs--are abundant in the human genome and have hi
84 inity of a transcription factor to different DNA motifs, as it can model complex interactions that ar
86 scripts that regulate the cell cycle and for DNA motifs associated with the transcription factor FOXP
88 ies demonstrates that Piwi binds a conserved DNA motif at approximately 72 genomic sites and inhibits
90 onic cell line H1, we mutated only the found DNA motifs at particular loci and the significant reduct
92 nt a method to measure the DeltaG degrees of DNA motifs at temperatures and buffer conditions of inte
93 ssociating genes frequently contain the same DNA motifs at their promoter regions, suggesting that po
100 we showed that in erythroid K562 cells these DNA motifs bound the following three transcription facto
101 controlled by Stat1/2 and Irf9 and the ISRE DNA motif, but others appeared dependent on non-canonica
103 res Rta to bind to multiple copies of an Rta DNA motif (called "CANT" or Rta-c) proximal to an RBP-Jk
104 zed with an ATP-binding aptamer-incorporated DNA motif can selectively release the intercalating doxo
106 broadly, these findings show that functional DNA motifs can be identified by machine learning analysi
107 ore, it has been speculated that these non-B DNA motifs can play regulatory roles in gene transcripti
110 er activity, and mutagenesis showed that the DNA motif CCCTCCT is essential for GATA-2 promoter activ
114 re, we demonstrate how "Coordinator," a long DNA motif composed of common motifs bound by many basic
115 gomeric complex binds to a unique, bipartite DNA motif comprising an E-box, CAGGTG, followed approxim
116 involving Lmo2 which can bind to a bipartite DNA motif comprising two E-box sequences approximately 1
117 by a novel mechanism and identify a specific DNA motif conducive to strong BLM binding and cleavage.
122 n receptor gene rearrangement is directed by DNA motifs consisting of a conserved heptamer and noname
123 ated by a pyknon, a short 20 nucleotide-long DNA motif contained in the N-BLR transcript and is targe
125 inducible hnRNP, which can recognize a novel DNA-motif, controls the expression of the CR2 gene.
126 is footprint, two unrelated 30-bp cis-acting DNA motifs (designated TOAD and FROG) function as positi
136 olid condensates is orchestrated by specific DNA motifs enriched in OR enhancers, which are likely to
137 was incorrect; that sentence should begin: "DNA motif-enrichment analysis of the subset-specific H3K
142 h synergistic interactions between consensus DNA motifs for binding of vitamin D receptor, AP1 and EL
143 a general design principle for pH-responsive DNA motifs for general DNA sequences (not limited to tri
144 ters the ability of Ikaros complexes to bind DNA motifs found in pericentromeric heterochromatin (PC-
146 e physical interaction of Myc with the E-box DNA motif has been extensively characterized, but it is
148 hese factors, their target genes and binding DNA motifs has been linked to various neuropsychiatric d
149 the breakpoint junctions revealed no common DNA motif; however, deletions, duplications, microhomolo
150 omplex (CBC) to cooperatively bind bipartite DNA motifs; however, the mode of HapX-DNA recognition ha
152 ified TFs that bind to three uncharacterized DNA motifs identified in DNase footprinting assays.
154 Unlike most TFs, NF-Y can access its target DNA motif in inactive (nonmodified) or polycomb-represse
155 TFs were shown to bind to the same GCC-like DNA motif in OsRMC promoter and to negatively regulate i
156 hree copies of a conserved 18-bp palindromic DNA motif in the promoter of each ACG family member.
159 to de novo discover significant co-occurring DNA motifs in 349 human DNase I hypersensitive site data
160 d E2A-Pbx1 exhibit tight binding to specific DNA motifs in conjunction with certain other homeodomain
163 key highlight is the successful assembly of DNA motifs in nickel-containing buffer at temperatures b
166 dentified significant enrichment of specific DNA motifs in the 1000 bp proximal promotor, some of whi
167 matode muscle genes, we identified conserved DNA motifs in the promoter regions using computational D
171 e predicted regulatory regions identified 31 DNA motifs, including 57.1% of experimentally validated
173 he integration of noncanonical and canonical DNA motif information yields new hypotheses on cobinding
175 Watson-Crick base pairing rules to assemble DNA motifs into diverse arrangements of geometric shapes
176 ect inverted repeat spaced by one nucleotide DNA motif, inverted repeat-1 (5'-AGGTCAcAGACCT-3'), as a
178 motif-based fashion, assuming that the same DNA motif is equally likely to be targeted regardless of
182 ial for binding to the vast majority of GATA DNA motifs, is strictly required for GATA-1-mediated ery
183 use monomeric Hox proteins bind very similar DNA motifs, it is unclear how they activate diverse deve
184 s gene transcription via a sequence-specific DNA motif known as the neuron-restrictive silencer eleme
186 hts of the CNN confirmed it detects familiar DNA motifs known to correlate with real variation, like
187 ysis revealed putative Lrp-binding consensus DNA motifs located in P(hilA), P(invF), and P(ssrA).
188 a complicated arrangement of A-box and B-box DNA motifs located on opposite ends of a sharply bent pa
189 to a given list of CpGs, and generating the DNA motif logo enriched in the genomic contexts of a giv
190 that TFs that preferentially bind divergent DNA motifs may bind overlapping genomic regions due to l
191 plified product strongly suggests that local DNA motifs may have contributed to the generation of thi
192 es of relatively frequent GC-rich cis-acting DNA motifs may offer reiterated binding sites to factors
194 Hot spot-enriched A-rich and CTT-repeat DNA motifs occurred upstream and downstream, respectivel
197 P1 sites with fast binding kinetics, whereas DNA motifs of ETS and homeodomain proteins are preferent
198 CaCse4p-rich regions not only lack conserved DNA motifs of point (<400 bp) centromeres and repeated e
199 he genome either by directly binding cognate DNA motifs or via protein-protein interactions with othe
200 searching genomic DNA sequences with genomic DNA motifs (or matrices) that are representative of the
202 study set of transcription factors and their DNA motifs, our method has a prediction accuracy of 59%
203 99 novel transcription factors and 70 novel DNA motifs, our method predicted 64 transcription-factor
204 er regions were found to contain a conserved DNA motif (p2(bp) box) identical in sequence and positio
207 to account together, we believe the coupling DNA motif pairs identified in this study can shed lights
208 -kind study, we have identified the coupling DNA motif pairs on long-range chromatin interactions in
210 i, where they associate with the TCF-4/LEF-1 DNA motif positioned in the promoters of several importa
212 n (IL)-2 promoter as well as to a homologous DNA motif present in the proximal segment of the interfe
213 and in vivo to critical homeodomain binding DNA motifs present in the neuronal Pomc enhancers nPE1 a
214 Importantly, the gene sets and associated DNA motifs provide a starting point with which to explor
215 structure predictions available, including Z-DNA motifs, quadruplex-forming motifs, inverted repeats,
218 ns of endosperm cap-enriched genes contained DNA motifs recognized by ethylene response factors (ERFs
219 sults suggest that unique ligands may switch DNA motifs recognized by ligand-dependent transcription
220 from transcription start sites and contained DNA motifs recognized by regulators of cell-type identit
222 mmand-line tool for the scanning of known TF DNA motifs represented as Position Weight Matrices (PWMs
225 scription factors bind a canonical consensus DNA motif, RYAAAYA (R = A/G, Y = C/T), as a monomer.
229 ulatory DNA sequences (ISS) containing a CpG DNA motif significantly inhibit airway eosinophilia and
230 n, were distinguished by clusters of a 10-bp DNA motif, suggesting a recruitment-and-spreading mechan
231 promoter region in these strains revealed a DNA motif (TAATGA) that was present in either one or two
234 pG (mCpG) sites and a specific nonmethylated DNA motif (TCCTGCNA) and represses transcription by recr
235 hFAST-1 protein was shown to bind to a novel DNA motif, TGT (G/T) (T/G)ATT, an exact copy of which wa
236 FOXC2, FOXM1, and FOXN1 to a canonical FkhP DNA motif that are greater at pH 7.0 compared with pH 7.
237 f the 100 promoters most enriched revealed a DNA motif that differs from the EBNA1 binding site in th
238 A helical sheets, and reveals a noncanonical DNA motif that has adaptive features that may be useful
241 nal analysis uncovered a novel homo-trimeric DNA motif that mediates the homo-trimeric DNA binding of
242 We used Gibbs sampling to define a CRP(Mt) DNA motif that resembles the cAMP receptor protein (CRP)
246 sms to maintain epigenetic stability near G4 DNA motifs that are dependent on either REV1 or on the W
248 r, TCF/Arm mediated repression by binding to DNA motifs that are markedly different from typical TCF-
249 detects and responds to hypo-methylated CpG DNA motifs that are most commonly found in microbial gen
250 ive elements, including L1 and L2 LINEs, and DNA motifs that are significantly enriched around inacti
252 te targetting of Pbx heterodimers to related DNA motifs that differ in the sequence of their 3' half-
253 vity, in contrast to that mediated by kappaB DNA motifs that do not efficiently bind p65 homodimers,
254 e tracts of variable-length repeats of short DNA motifs that exhibit high rates of mutation in the fo
255 are the most well-characterized noncanonical DNA motifs that have been detected in vivo with either p
256 ties, and this may be useful for identifying DNA motifs that have similar functional properties that
258 network approach called GBNet to search for DNA motifs that may be cooperative in transcriptional re
259 umans and point to novel vertebrate-specific DNA motifs that might play a selective role in TATA-inde
260 do not appear to be demarcated by the usual DNA motifs that punctuate transcription in familiar euka
261 clones carried short (30-53 bp), repetitive DNA motifs that were often degenerate, overlapping, and
262 es of structurally but not textually related DNA motifs, that is, motifs whose consensus sequences ar
266 bes and 2D arrays assembled from three novel DNA motifs, the 6-helix bundle (6HB), the 6-helix bundle
267 voring a conformation that can bind specific DNA motifs, thereby serving to either activate or repres
268 ate and high-throughput method for measuring DNA motif thermodynamics called TEEM (Toehold Exchange E
269 2s target euchromatic gene loci via specific DNA motifs, they are likely integral components of heter
270 ethylated cytosine-phosphate-guanosine (CpG) DNA motifs through toll-like receptor 9, and we found th
272 AIR lncRNA preferentially occupies a GA-rich DNA motif to nucleate broad domains of Polycomb occupanc
275 tiation, Twist2 competes with MyoD at shared DNA motifs to direct global gene transcription and repre
277 To generate a nearly complete list of human DNA motifs under given conditions, we employed a novel a
279 are attributable to variation in a specific DNA motif upstream of the cagA transcriptional start sit
280 superstructures consisting of heterogeneous DNA motifs using dsDNA in conjunction with more complex,
281 osatellites are a tract of repetitive, short DNA motifs (usually 1 to 6 bp) abundant in eukaryotic ge
282 ion factors (TFs) to short sequence-specific DNA motifs, usually located at the gene regulatory regio
286 e signaling and structural features into the DNA motifs, we envision diverse applications in biosensi
287 lthough the KSHV genome contains >100 RBP-Jk DNA motifs, we show that none of the four isoforms of ac
289 DNA with RNA dangling-end motifs shows that DNA motifs with 5' dangling ends contribute to stability
290 te to this goal by combining stable branched DNA motifs with cohesive ends to produce programmed nano
292 ant role in the assembly of nucleosomes, and DNA motifs with high specificity to nucleosomes have bee
294 pment in mice and humans through a conserved DNA motif within Alu/B1 elements located in the promoter
297 howed that the distribution of several non-B DNA motifs within intergenic regions separating divergen
299 on-B DNA transition-susceptible sites (non-B DNA motifs) within the context of the operon structure o
300 mapping indicates both domains bind poly(C) DNA motifs without disrupting the KH1-KH2 interaction.