コーパス検索結果 (1語後でソート)
通し番号をクリックするとPubMedの該当ページを表示します
1 coimmunoprecipitate with Hys2, a subunit of DNA polymerase delta.
2 ncer-cell DNA replication and interacts with DNA polymerase delta.
3 flap by the strand displacement activity of DNA polymerase delta.
4 , Rad27p, or the proofreading exonuclease of DNA polymerase delta.
5 d27p, or the DNA proofreading exonuclease of DNA polymerase delta.
6 late translesion synthesis by Pol zeta or by DNA polymerase delta.
7 tigen (PCNA), replication factor C (RFC) and DNA polymerase delta.
8 nerated via strand-displacement synthesis by DNA polymerase delta.
9 enes encoding the Pol3 and Cdc27 subunits of DNA polymerase delta.
10 to mutations affecting ORC, Mcm proteins, or DNA polymerase delta.
11 lap endonuclease 1 (FEN1), DNA ligase I, and DNA polymerase delta.
12 topoisomerase III, replication protein A and DNA polymerase delta.
13 reconstitute fully active recombinant human DNA polymerase delta.
14 6, and p12 have been assigned as subunits of DNA polymerase delta.
15 isiae, POL3 encodes the catalytic subunit of DNA polymerase delta.
16 utation in the 3'-->5' exonuclease domain of DNA polymerase delta.
17 , a temperature-sensitive mutation affecting DNA polymerase delta.
18 (PCNA), a requisite processivity factor for DNA polymerase delta.
19 at supported PCNA-dependent DNA synthesis by DNA polymerase delta.
20 p50 interacts with the catalytic subunit of DNA polymerase delta.
21 art on the 3'-to-5' proofreading activity of DNA polymerase delta.
22 in other genes, including the gene encoding DNA polymerase delta.
23 (13D5) inhibited the activity of calf thymus DNA polymerase delta.
24 similarity to the small subunit of mammalian DNA polymerase delta.
25 NA polymerase III, the analogue of mammalian DNA polymerase delta.
26 ar antigen (PCNA), a processivity factor for DNA polymerase delta.
27 l peptides of the catalytic subunit of human DNA polymerase delta.
28 excision-independent mechanism that involves DNA polymerase delta.
29 for cells with defects in the lagging-strand DNA polymerase delta.
30 endonuclease Rad27 (human FEN1) coupled with DNA polymerase delta.
31 creasing the strand-displacement activity of DNA polymerase delta.
32 catalytic residues of Plasmodium falciparum DNA polymerase delta.
33 , Rad27, or strand-displacement synthesis by DNA polymerase delta.
34 section machineries, Rad1-Rad10 nuclease and DNA polymerase delta.
35 trand displacement DNA synthesis activity of DNA polymerase delta.
36 rier for the strand displacement activity of DNA polymerase delta.
37 replication protein A (RPA), RFC, PCNA, and DNA polymerase delta.
38 merase epsilon as compared to lagging-strand DNA polymerase delta.
39 0 (RPA70), replication factor C1 (RFC1), and DNA polymerase delta.
40 ssDNA template and inhibits DNA synthesis by DNA polymerase delta.
41 e first evidence for the targeting of PP1 to DNA polymerase delta.
46 of CRL4(Cdt2), i.e. the direct regulation of DNA polymerase delta, adding to its known functions in t
47 such as DNA polymerase beta and subunits of DNA polymerase delta along with the EBV-encoded DNase BG
48 cts were competent for DNA replication using DNA polymerases delta, alpha, and possibly epsilon, with
50 tion depends on the proofreading activity of DNA polymerase-delta, although the repair proteins Msh2,
51 The repair reaction displays specificity for DNA polymerase delta, an effect that presumably reflects
53 creases strand-displacement DNA synthesis by DNA polymerase delta and allows DNA replication across a
57 affinities of PCNAs for the subunit Pol32 of DNA polymerase delta and for T2-amino alcohol, a small-m
58 ding motif, includes a sequence conserved in DNA polymerase delta and implicated in its PCNA binding.
59 teins which bound to PCNA-Sepharose included DNA polymerase delta and straightepsilon, PCNA, the 37 a
60 udding yeast) that impede the interaction of DNA polymerase delta and the 5'-flap endonuclease Rad27/
62 etween cdc19+ and genes encoding subunits of DNA polymerase delta and the replication initiator cdc18
64 ences within FRA16D by the replicative human DNA polymerases delta and alpha, and with human cell-fre
65 of defects in the exonuclease activities of DNA polymerases delta and epsilon (conferred by the pol3
66 yotes, processive DNA synthesis catalyzed by DNA polymerases delta and epsilon (pol delta and epsilon
68 east, we confirm the strand specificities of DNA polymerases delta and epsilon and show that the PCNA
71 The resulting excision gap is filled in by DNA polymerases delta and epsilon as revealed by the 'ph
72 3'-->5' exonuclease activity of replicative DNA polymerases delta and epsilon but did not enhance th
74 eric RNA-DNA primers of a limited length for DNA polymerases delta and epsilon to initiate DNA replic
75 proofreading) by the exonuclease activity of DNA polymerases delta and epsilon, and post-replication
76 ar antigen (PCNA), a processivity factor for DNA polymerases delta and epsilon, is essential for both
77 ar antigen (PCNA), a processivity factor for DNA polymerases delta and epsilon, is involved in DNA re
78 e Okazaki fragments sequester PCNA, RFC, and DNA polymerases delta and epsilon, which prevents normal
89 s with somatic mutations in two of the major DNA polymerases, delta and epsilon, that replicate the g
91 This sequence was found to be present on DNA polymerase delta, and a peptide conforming to this s
92 r antigen clamp loader replication factor C, DNA polymerase delta, and DNA ligase I in the absence of
95 involved in DNA synthesis, such as PCNA and DNA polymerase delta, are concentrated in perinucleolar
96 argue that DNA polymerase zeta, rather than DNA polymerase delta as previously suggested, is respons
98 red for PCNA-dependent BER (AP endonuclease, DNA polymerases delta, beta and DNA ligase, and FEN1 end
99 s arrest is not due to 5-FU lesions blocking DNA polymerase delta but instead depends, in part, on th
100 ed capacity in enhancing the processivity of DNA polymerase delta but showed no deficiency in stimula
101 merase, and the most pure fraction contained DNA polymerase delta but was free of detectable DNA poly
103 re isolated with highly purified calf thymus DNA polymerase delta by conventional chromatography.
106 or the replicative RFC in the PCNA-dependent DNA polymerase delta-catalyzed DNA replication reaction.
107 unwound large (CTG)(n) hairpins and promoted DNA polymerase delta-catalyzed DNA synthesis using a (CT
108 to its native counterpart in (i) supporting DNA polymerase delta-catalyzed PCNA-dependent DNA chain
110 Likewise, expression of the intracellular DNA polymerase delta cofactor/proliferating-cell nuclear
115 cteristic for authentic RF-C: stimulation of DNA polymerase delta DNA synthesis on singly primed sing
116 that impede replication forks, necessitating DNA polymerase delta (DNAPdelta)-mediated replication fo
118 BER factors flap endonuclease 1 (FEN-1) and DNA polymerase delta/epsilon was also observed, suggesti
119 ovement through undamaged DNA slows down and DNA polymerase delta fails to associate with replicating
121 r antigen, the replication factor C complex, DNA polymerase delta, flap endonuclease 1 and DNA ligase
122 o of the several sites involved in tethering DNA polymerase delta for processive DNA synthesis during
123 inity purification of recombinant p50 and of DNA polymerase delta from calf thymus or HeLa extracts.
124 er, rigorous purification of human or bovine DNA polymerase delta from natural sources has usually yi
125 ing of Okazaki fragments) and POL3 (encoding DNA polymerase delta) genes on the stability of a minisa
127 tated with human p50, as well as calf thymus DNA polymerase delta heterodimer, but not with p125 alon
128 ome maintenance complex component (MCM7) and DNA polymerase delta hindering replication fork progress
129 d to enhance the processivity of calf thymus DNA polymerase delta holoenzyme similar to calf thymus P
133 serve as the lagging strand replicase, like DNA polymerase delta in eukaryotes, but instead function
134 th pol3+, which encodes the large subunit of DNA polymerase delta in fission yeast, and the Cdc1 prot
136 hese observations, we infer a requirement of DNA polymerase delta in post-replicative bypass of UV-da
137 antly alter the ability of PCNA to stimulate DNA polymerase delta in the absence of RFC but substanti
138 we have evaluated possible participation of DNA polymerase delta in the excision step of repair.
139 he coding region of the catalytic subunit of DNA polymerase delta in XP variant cell lines revealed t
140 antigen (PCNA), the processivity factor for DNA polymerase delta, in mature cells of Nicotiana benth
141 ed levels of Pol3p, the catalytic subunit of DNA polymerase delta, induce instability at these same s
144 se results suggest that the small subunit of DNA polymerase delta is essential for functional interac
145 roliferating cell nuclear antigen (PCNA) and DNA polymerase delta is essential for processive DNA syn
146 POLD1 gene encoding the catalytic subunit of DNA polymerase delta is G/C-rich and does not contain a
147 de that both the quantity and the quality of DNA polymerase delta is important in ensuring genome sta
149 establish that the interaction of PCNA with DNA polymerase delta is mediated through the small subun
150 e for deletions at AT-rich structures, while DNA polymerase delta is protective, but not in a repeat-
152 h repair to the depleted extract, indicating DNA polymerase delta is required for mismatch repair in
157 at degradation of p12, the fourth subunit of DNA polymerase delta, is critical for inhibiting fork pr
158 rast to the native heterodimeric calf thymus DNA polymerase delta, is not responsive to stimulation b
159 pared with those of the native heterodimeric DNA polymerase delta isolated from fetal calf thymus, an
160 root of the clade containing all eukaryotic DNA polymerase delta members but that this clade does no
161 in the "proofreading" exonuclease domain of DNA polymerase delta) mutations were synthetically letha
162 action cannot be promoted by the replicative DNA polymerase delta or by other TLS polymerases such as
163 n in this process have suggested that either DNA polymerase delta or DNA polymerase epsilon may be in
164 can facilitate DNA replication by tethering DNA polymerase delta or DNA polymerase epsilon to the DN
165 nuclear antigen onto DNA, where it recruits DNA polymerase delta or epsilon to the primer terminus a
166 achieved by including highly purified human DNA polymerase delta or epsilon, PCNA, RFC, and DNA liga
169 (PCNA) is a processivity factor required for DNA polymerase delta (or epsilon)-catalyzed DNA synthesi
171 nstrated that the catalytic subunit of human DNA polymerase delta (p125) expressed in baculovirus-inf
172 ctly interacts with the catalytic subunit of DNA polymerase delta (p125), and promotes its recruitmen
173 gh small but detectable levels were seen for DNA polymerases delta (+PCNA) and straightepsilon (- PCN
175 model whereby the high-fidelity replicative DNA polymerase delta performs recombination-associated D
179 ed for processive DNA synthesis catalyzed by DNA polymerase delta (pol delta) and polymerase epsilon.
180 ectrophoresis, is formed between calf thymus DNA polymerase delta (pol delta) and synthetic oligonucl
181 aturation requires the coordinated action of DNA polymerase delta (Pol delta) and the FLAP endonuclea
182 itiated by an RNA/DNA primer and extended by DNA polymerase delta (pol delta) and the replication cla
184 Here we identify subunits of the replicative DNA polymerase delta (Pol delta) as promoters of Alt-NHE
185 ability to promote DNA synthesis by purified DNA polymerase delta (pol delta) both on unmodified temp
189 DNA helicase that partially co-purifies with DNA polymerase delta (pol delta) from fetal bovine thymu
192 the p12 subunit in the function of the human DNA polymerase delta (Pol delta) holoenzyme by comparing
193 trand templates are initially encountered by DNA polymerase delta (pol delta) holoenzymes comprised o
195 we constructed a series of recombinant human DNA polymerase delta (Pol delta) in which one or two of
201 replication and in several types of repair, DNA polymerase delta (pol delta) is assisted by replicat
210 (PCNA) promotes DNA synthesis by calf thymus DNA polymerase delta (pol delta) past several chemically
214 ouble mutant allele, which causes defects in DNA polymerase delta (Pol delta) proofreading (pol3-01)
215 of proliferating cell nuclear antigen, yeast DNA polymerase delta (Pol delta) replicated DNA at a rat
216 telomere damage to establish predominance of DNA polymerase delta (Pol delta) through its POLD3 subun
217 dihydroguanine (8-oxoG) by fetal calf thymus DNA polymerase delta (pol delta) was examined by steady-
218 at interacts with the small subunit (p50) of DNA polymerase delta (pol delta) was identified in a two
219 analysis of the 3'-->5' exonuclease of yeast DNA polymerase delta (Pol delta) we have discerned addit
220 dination of strand displacement synthesis by DNA polymerase delta (Pol delta) with 5.-flap cutting by
221 ow here that WRN functionally interacts with DNA polymerase delta (pol delta), a eukaryotic polymeras
223 ough tight coordination of the activities of DNA polymerase delta (Pol delta), flap endonuclease 1 (F
224 Although PCNA interacts with the enzymes DNA polymerase delta (Pol delta), flap endonuclease 1 (F
225 ed to study complexes formed among mammalian DNA polymerase delta (pol delta), proliferating cell nuc
226 lizing antibodies suggested a role for yeast DNA polymerase delta (Pol delta), RFC and PCNA in LLR re
228 an will be more internal errors generated by DNA polymerase delta (Pol delta), which takes over for P
229 e of the main DNA replicases in human cells, DNA polymerase delta (Pol delta), with an error-prone va
230 iscontinuous strand that takes place in both DNA polymerase delta (Pol delta)- and DNA polymerase (Po
236 positions of components of the DNA-dependent DNA polymerase delta (pol delta).proliferating cell nucl
239 The mutator effects of mutations in the DNA polymerase delta (POL3) gene and the recombinational
240 trand synthesis: The processivity subunit of DNA polymerase delta, Pol32, and the catalytic domain of
241 on with three essential replication enzymes: DNA polymerase delta (POLD1), DNA primase (PRIM1), and m
242 a gene orthologous with the third subunit of DNA polymerase delta (POLD3), a previously uncharacteriz
244 on, molecular and functional analyses of the DNA polymerase delta (Poldelta) complex, and T- and B-ce
252 tation (D400A) in the proofreading domain of DNA polymerase delta (poldelta, encoded by the Pold1 gen
253 tigen (PCNA) for functional interaction with DNA polymerases delta (Poldelta) and epsilon (Pol epsilo
255 tations in the POLD1 and POLE genes encoding DNA polymerases delta (Poldelta) and varepsilon (Polvare
259 the Bloom syndrome helicase (BLM) stimulates DNA polymerase delta progression across telomeric G-rich
260 synthesis and progression by the replicative DNA polymerase delta/proliferating cell nuclear antigen/
261 ombination-associated DNA synthesis and that DNA polymerase delta promotes recombination-associated D
262 Finally, a diploid strain with a defect in DNA polymerase delta proofreading exhibits a higher muta
265 ns of 4 to 14 bases to examine the impact of DNA polymerase delta proofreading on mutation avoidance.
266 ion at L604 in the polymerase active site of DNA polymerase delta reduces life span, increases genomi
267 a reaction requiring S. pombe Uve1p, Rad2p, DNA polymerase delta, replication factor C, proliferatin
268 of the catalytic and small subunits of human DNA polymerase delta results in formation of a stable, f
269 the processivity or proofreading activity of DNA polymerase delta shortened hetDNA length or reduced
270 ffects of recombinant p50 on the activity of DNA polymerase delta showed that p50 is able to slightly
271 of DNA ligase III, while those catalyzed by DNA polymerase delta/straightepsilon appeared to be more
273 ynonymous, single nucleotide polymorphism in DNA polymerase delta subunit 1 (MePOLD1) located within
274 , DNA polymerase zeta, Rev1 protein, and the DNA polymerase delta subunit, Pol32, in the bypass of an
275 air; however, the identity of the subunit of DNA polymerase delta that directly interacts with PCNA h
276 m of yeast Rad51, Rad54, RPA, PCNA, RFC, and DNA polymerase delta that loading of PCNA by RFC targets
277 by heterozygosity for a missense mutation in DNA polymerase delta that reduces its proofreading activ
278 fect in the catalytic subunit of replicative DNA polymerase delta that results in increased rates of
279 nuclear antigen, replication protein A, and DNA polymerase delta that supports Exo1-independent repa
280 determine which of the two subunits of core DNA polymerase delta, the 125-kDa catalytic subunit or t
281 aturation by the PCNA-coordinated actions of DNA polymerase delta, the flap endonuclease FEN1, and DN
283 epsilon incorporated the analogs showed that DNA polymerase delta, the most sensitive of the DNA poly
284 strand displacement synthesis carried out by DNA polymerase delta, the PCNA clamp, its loader RFC, an
285 pears to regulate polymerase handoff, and in DNA polymerase delta, the redox switch provides a means
287 In results presented here, Pif1 promoted DNA polymerase delta to displace strands that achieve a
288 the ability of the p125 catalytic subunit of DNA polymerase delta to engage in protein-protein intera
289 se delta that loading of PCNA by RFC targets DNA polymerase delta to the D loop formed by Rad51 prote
290 roliferating cell nuclear antigen (PCNA) and DNA polymerase-delta to execute conservative DNA repair
291 g replication, here we present evidence that DNA polymerase delta universally participates in initiat
292 ta1N, proliferating cell nuclear antigen and DNA polymerase delta was found to repair substrates cont
293 The fidelity of Schizosaccharomyces pombe DNA polymerase delta was measured in the presence or abs
297 ability of ATM to stimulate DNA synthesis by DNA polymerase delta, which is implicated in both DNA re
300 t is essential for functional interaction of DNA polymerase delta with PCNA and for highly processive