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1 nt DNA ligase and/or archeal-eukaryotic-type DNA primase.
2 ed by mutations of Schizosaccharomyces pombe DNA primase.
3 leads to elevated RNA primer synthesis by T7 DNA primase.
4  biochemical characterisation of an archaeal DNA primase.
5 s within the M. smegmatis dnaG gene encoding DNA primase.
6 involves interactions of these proteins with DNA primase.
7 vivo, primers are synthesized on-template by DNA primase.
8 anism and a fold similar to that of archaeal DNA primase.
9  polymerase requires RNA primers produced by DNA primase.
10 nsferases and archaeal homologs of DnaG-type DNA primases.
11 eria and eukaryotes requires the activity of DNA primase, a DNA-dependent RNA polymerase that lays sh
12 ost all organisms depends on the activity of DNA primase, a DNA-dependent RNA polymerase that synthes
13 ory factors, and primosome (DNA helicase and DNA primase activities).
14 e for Mn(II) over Mg(II), suggesting that T7 DNA primase activity modulation when bound to Mn(II) is
15  bound to single-stranded DNA and stimulated DNA primase activity only in the presence of AAF-132.
16 s the N-terminal domain in T7 gp4 contains a DNA primase activity, this function is lost in metazoan
17 A replication elongation by interfering with DNA primase activity.
18                     Slow primer release from DNA primase allows the polymerase to engage the complex
19 ll molecule inhibitors of the activity of T7 DNA primase, an ideal model for bacterial primases due t
20  replication system of bacteriophage T7 both DNA primase and DNA helicase activities are contained wi
21 e human primosome, a four-subunit complex of DNA primase and DNA polymerase alpha (Polalpha), plays a
22 des with that of the archeal-eukaryotic-type DNA primase and genes for prokaryotic Ku homologs form p
23 A replication, BSLF1 and BALF5, encoding EBV DNA primase and polymerase, respectively, were SM depend
24 primase template affinity and stimulate both DNA primase and polymerase-alpha activities in vitro.
25 on of the amino acid sequences of eucaryotic DNA primase and the family X polymerases indicates that
26 nd extension effected by cooperation between DNA primase and the lagging-strand polymerase.
27 nstants and binding mode for interactions of DNA primase and thymidylate synthetase (TS) with high an
28 imPol is a recently discovered DNA-dependent DNA primase and translesion synthesis DNA polymerase fou
29  in the HU-14 noncoding region between dnaG (DNA primase) and rpoD (sigA).
30    In contrast, expression of DNA pol alpha, DNA primase, and RPA was down-regulated in PARP-antisens
31               The redox switch in eukaryotic DNA primases appears to regulate polymerase handoff, and
32 NA polymerase and the zinc-finger domains of DNA primase are involved in the stabilization of the pri
33 A replication, structural data on eukaryotic DNA primase are lacking.
34                                              DNA primases are enzymes whose continual activity is req
35                                              DNA primases are essential for the initiation of DNA rep
36                                              DNA primases are pivotal enzymes in chromosomal DNA repl
37                                    Replisome DNA primases are responsible for the synthesis of short
38                                              DNA primases are template-dependent RNA polymerases that
39 port PRIM1 encoding the catalytic subunit of DNA primase as a novel disease gene.
40 examined the effects of Mn(2+) on eukaryotic DNA primase both in the presence and absence of 5 mM Mg(
41 emonstrate that the [4Fe4S] cluster in human DNA primase can make use of this chemistry to coordinate
42                                         Most DNA primases can be divided into two classes.
43                                              DNA primases catalyze the synthesis of oligoribonucleoti
44                                              DNA primases catalyze the synthesis of oligoribonucleoti
45                                              DNA primases catalyze the synthesis of the oligoribonucl
46 tion and biochemical characterization of the DNA primase complex and its subunits from the archaeon T
47                         The T. kodakaraensis DNA primase complex is a heterodimer containing stoichio
48   Supplementation of such reactions with the DNA primase complex supported lagging strand formation a
49       Photo-cross-linking of single-stranded DNA-primase complexes revealed that whereas the isolated
50                     The p58 subunit of human DNA primase contains a region, M288-K344, that is homolo
51                    We have identified 56-kDa DNA primases defective in primer delivery by screening f
52  to contain DNA polymerases alpha and delta, DNA primase, DNA helicase, DNA ligase, and topoisomerase
53 l DNA (vDNA), including MCM complex members, DNA primase, DNA polymerase alpha, DNA ligase, and repli
54                                    Bacterial DNA primase DnaG synthesizes RNA primers required for ch
55      The mechanism of action of B. anthracis DNA primase (DnaG(BA)) may be described in several disti
56 of unknown function the structural genes for DNA primase (dnaG) and the major sigma factor of RNA pol
57 n be reversed by over-expression of the host DNA primase, DnaG.
58                     A novel peptide from the DNA primase, DNAP(211-223), was also found.
59                                           T7 DNA primase does not catalyze extension synthesis by a Z
60                             The gene for the DNA primase encoded by Salmonella typhimurium bacterioph
61                                              DNA primase facilitates binding of DNA helicase to ssDNA
62       We have purified to near homogeneity a DNA primase from a mitochondrial fraction of the trypano
63 e mechanistic characteristics of recombinant DNA primase from Bacillus anthracis.
64 ars to develop a better understanding of how DNA primase from herpes simplex virus I catalyzes primer
65 ity and mechanism of NTP misincorporation by DNA primase from herpes simplex virus-1.
66 the identification and characterisation of a DNA primase from the thermophilic methanogenic archaeon
67 m of primase function and are applicable for DNA primases from other species.
68  nuclear protein (germinal center-associated DNA primase) (GANP), CD74, CD22, NF-kappaB, elongation f
69        We describe here a Trypanosoma brucei DNA primase gene, PRI1, that encodes a 70-kDa protein th
70                                              DNA primase harboring lysine at position 69 fails to sta
71 As has not been possible since a kinetoplast DNA primase has not been available.
72 ance and biochemical assays, we show that T7 DNA primase has only a slightly higher affinity for DNA
73                                              DNA primase has two subunits, Spp1 and Spp2 (S. pombe pr
74 The zinc-binding domain (ZBD) of prokaryotic DNA primases has been postulated to be crucial for recog
75 superior in de novo synthesis compared to T7 DNA primase having a shorter linker.
76 e deaminase, and in DNA replication, such as DNA primase, helicase, type A DNA polymerase, and predic
77 nique long 52 gene (UL52; a component of the DNA primase/helicase complex), bICP4, IEtu2, and the uni
78 encoding unique long 52 (UL-52; component of DNA primase/helicase complex), Circ, bICP4, and IEtu2 we
79  63-kDa gene 4 protein of phage T7 is also a DNA primase in that it catalyzes the synthesis of oligon
80                                 Wild-type T7 DNA primase is 10-fold superior in de novo synthesis com
81                                           T7 DNA primase is composed of a catalytic RNA polymerase do
82  In the bacteriophage T7 replication system, DNA primase is encoded by gene 4 of the phage.
83           The stabilization of the primer by DNA primase is necessary for DNA polymerase to initiate
84 , a single archaeo-eukaryotic primase (AEP), DNA primase, is required for the initiation and progress
85 ence of dATP, glycerol, and Tris buffer, the DNA primase isolated from Thermococcus kodakaraensis cat
86  interaction of the C-terminal domain of the DNA primase large subunit (p58C) with the primer 5'-end,
87                          Mechanisms by which DNA primase levels might influence the faf-dependent cel
88                                           T7 DNA primase, like other primases, shares limited homolog
89 essor mutations of the temperature-sensitive DNA primase mutant dnaG2903 have been characterized.
90  results explain functional defects in human DNA primase mutants and provide insights into primosome
91                                          The DNA primase of bacteriophage T7 has a zinc-binding motif
92 ng mutagenesis of the zinc-binding domain of DNA primase of bacteriophage T7 using a bacterial homolo
93                            The 63-kDa gene 4 DNA primase of phage T7 catalyzes the synthesis of oligo
94 nly two of 12 potential priming sites of the DNA primase of the pRN1 replicon, but nearly all these m
95 can now be cited demonstrating how the term 'DNA primase' only describes a very narrow subset of thes
96 required for replication initiation, and the DNA primase-polymerase in eukaryotes is pol alpha.
97 involving the ubiquitin ligase RFWD3 and the DNA primase-polymerase PRIMPOL to facilitate gapped DNA
98 rbed DNA replication due to repriming by the DNA primase-polymerase PRIMPOL.
99                           PrimPol is a human DNA primase-polymerase which restarts DNA synthesis beyo
100              In many prokaryotes, a specific DNA primase/polymerase (PolDom) is required for nonhomol
101                           Antibodies against DNA primase precipitated telomerase activity from all th
102 replication, DNA polymerase alpha (pol1-17), DNA primase (pri2-1), and Rad27p (rad27 delta) also grea
103 ation enzymes: DNA polymerase delta (POLD1), DNA primase (PRIM1), and minichromosome 6 (MCM6).
104                                              DNA primases provide oligoribonucleotides for DNA polyme
105 ymerases, DNA helicase, type B cyclin genes, DNA primases, radiation sensitive genes, repaire related
106 hat besides the single iteron, a neighboring DNA primase recognition element called G site is essenti
107                             Bacteriophage T7 DNA primase recognizes 5'-GTC-3' in single-stranded DNA.
108                                           T7 DNA primase recognizes the sequence 5'-NNGTC-3' via a zi
109                  Application of the model to DNA primase revealed a preference in the enzyme's second
110     To identify the catalytic core of the T7 DNA primase, single-point mutations were introduced into
111                                     Although DNA primase structures are available from archaea and ba
112 initiation, we analyzed mutations of the two DNA primase subunit genes of Schizosaccharomyces pombe,
113 nts, helicases, an RNA-binding protein and a DNA primase subunit.
114 ncentration in determining where calf thymus DNA primase synthesizes a primer on a DNA template was e
115                        At a replication fork DNA primase synthesizes oligoribonucleotides that serve
116                                              DNA primase synthesizes short RNA oligonucleotides that
117                                              DNA primase synthesizes short RNA primers that are requi
118                                        Human DNA primase synthesizes short RNA primers that DNA polym
119                                        Human DNA primase synthesizes short RNA primers that DNA polym
120                                       The T7 DNA primase synthesizes tetraribonucleotides that prime
121   The discovery of an iron-sulfur cluster in DNA primase that contributes to enzymatic activity provi
122 arity to the small subunit of the eukaryotic DNA primase (the p50 subunit of the polymerase alpha-pri
123 quires the replicative DnaB helicase and the DNA primase, the DnaG gene product.
124 im gene encodes the large subunit (60 kD) of DNA primase, the part of DNA polymerase alpha that synth
125                            The ability of T7 DNA primase to catalyze template-directed oligoribonucle
126 uires an oligoribonucleotide, synthesized by DNA primase, to initiate the synthesis of an Okazaki fra
127 alysis revealed that upon binding Mn(II), T7 DNA primase undergoes conformational changes near the me
128 cating NADH-quinone reductase subunit A, and DNA primase were expressed in HLA-B27(+) cells, and thei
129 ssential DNA polymerases alpha and delta and DNA primase were required.
130                   Until relatively recently, DNA primases were viewed simply as a class of proteins t
131 t organisms, DNA replication is initiated by DNA primases, which synthesize primers that are elongate
132  transfer, the IncP1 plasmid R751, encodes a DNA primase with low specificity for initiation.
133 trand holoenzyme, and by the presence of the DNA primase with ribonucleoside triphosphates.
134                    The inclusion of multiple DNA primases within a whole domain of organisms complica

 
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