ライフサイエンスコーパス: DNA-binding activity

1 , which in Ets-1 allosterically inhibits the DNA binding activity.

2 ative function is known to inhibit C/EBPbeta DNA binding activity.

3 f the p50/p65 heterodimer inhibits NF-kappaB DNA binding activity.

4 also impairs both BAF's dimerization and its DNA binding activity.

5 rsed the inhibiting effect of H2S on the p65 DNA binding activity.

6 ing these contacts dramatically affects MepR-DNA binding activity.

7 decreased, and there was a loss of NF-kappaB DNA binding activity.

8 nuclear localization of Sp1 and affects its DNA binding activity.

9 s in the hinge, also loses its site-specific DNA binding activity.

10 chromosome via an ATP-dependent nonspecific DNA binding activity.

11 phosphorylation, nuclear translocation, and DNA binding activity.

12 osphorylation of CREB in vitro inhibited its DNA binding activity.

13 avirus E1 and E2 proteins by modifying their DNA binding activity.

14 ter DNA in vitro, which is dependent on LuxR DNA binding activity.

15 ragment compounds to find inhibitors of AgrA DNA binding activity.

16 reduced NF-kappaB nuclear translocation and DNA binding activity.

17 lfenic acid results in a ~4-fold increase in DNA binding activity.

18 nstructured aggregates with severely reduced DNA binding activity.

19 s nuclear localization and sequence-specific DNA binding activity.

20 tTR domain, a site known to be important for DNA binding activity.

21 free factor, which, we propose, inhibits its DNA binding activity.

22 tores p53 wild type conformation and rescues DNA binding activity.

23 at the polyomaviruses share this nonspecific DNA binding activity.

24 onse in osteoblasts by suppressing C/EBPbeta DNA binding activity.

25 DKN1A in a manner that is independent of its DNA binding activity.

26 erstood about how phosphorylation impacts ER-DNA binding activity.

27 by both histone and previously unrecognized DNA binding activity.

28 e-exposed cysteines without compromising its DNA binding activity.

29 or NF erythroid-2-related factor 2 level and DNA binding activity.

30 region of these factors autoregulates their DNA binding activity.

31 regulation via a mechanism independent of IE DNA binding activity.

32 -gamma target genes and increased PPAR-gamma DNA-binding activity.

33 T3-dependent gene expression by blocking its DNA-binding activity.

34 sential for homodimer formation and enhanced DNA-binding activity.

35 nts with transient neonatal diabetes abolish DNA-binding activity.

36 lei of irradiated cells and attenuated their DNA-binding activity.

37 stream target genes reflects increased E2F-1 DNA-binding activity.

38 cal zinc finger motif with sequence-specific DNA-binding activity.

39 lation at lysine 310, thereby inhibiting its DNA-binding activity.

40 e a conformational change that gives rise to DNA-binding activity.

41 sed HIF-1alpha protein expression as well as DNA-binding activity.

42 domain destabilize the structure and reduce DNA-binding activity.

43 nding surface, consistent with their reduced DNA-binding activity.

44 depends on a subunit, Teb1, with autonomous DNA-binding activity.

45 highly conserved residues in NAD-responsive DNA-binding activity.

46 rate binding domain and Hsp70 regulates Hsf1 DNA-binding activity.

47 es and find that surplus Hsp70 inhibits Hsf1 DNA-binding activity.

48 53 via phosphorylation and activation of p53 DNA-binding activity.

49 sociation with Rb and without decreasing its DNA-binding activity.

50 also find that both BRG1 and hBRM BRDs have DNA-binding activity.

51 ed structure, but it does not have ATPase or DNA-binding activity.

52 ols their translocation into the nucleus and DNA-binding activity.

53 scriptional repressor with sequence-specific DNA-binding activity.

54 haracterization of the SsOGT biochemical and DNA binding activities.

55 naA, is highly conserved and has two crucial DNA binding activities.

56 cer and anti-obesity drugs by inhibiting its DNA-binding activities.

57 ied TFs with methylated CpG (mCpG)-dependent DNA-binding activities.

58 2 oncogenicity relied on its demethylase and DNA-binding activities.

59 E1 results in the loss of sequence-specific DNA binding activity, a feature that is also conserved i

60 inactivated Cic by selectively disabling its DNA-binding activity, a mutation that causes derepressio

61 nding microarrays to assay sequence-specific DNA binding activity across 41 reference and 117 variant

62 erexpression reduces the amount of NF-kappaB DNA binding activity, activity of the upstream kinase IK

63 gnificant impact of the Pro76Leu mutation on DNA-binding activities, alterations in transactivating f

64 al transcription factors that regulate their DNA binding activities and aid in specific assembly of t

65 ed mutations in the B3 domain that disrupted DNA binding activity and characterized gene regulation b

66 ter inhibited CREB-mediated gene expression, DNA binding activity and chromatin occupancy proportiona

67 of the NF-kappaB p65 protein, as well as the DNA binding activity and DNA binding level of NF-kappaB

68 at the short Blimp-1Deltaexon7 isoform lacks DNA binding activity and fails to bind G9a or HDAC1/2 bu

69 helix transcription factor family that lacks DNA binding activity and has tumor suppressor function.

70 , and this was associated with enhanced CREB DNA binding activity and induction of IL-10.

71 showed that IR persistently induced NFkappaB DNA binding activity and NFkappaB-dependent TNFalpha tra

72 ciated with increased in vitro p65 NF-kappaB DNA binding activity and p65 recruitment to the endogeno

73 uently, CS exposure resulted in enhanced Sp1-DNA binding activity and Sp1 trans-activation.

74 he C-terminal cleavage fragment retains both DNA binding activity and the ability to interact with AP

75 to evaluate TF variants for their impact on DNA binding activity and used universal protein-binding

76 has been well studied for over a decade, the DNA-binding activities and the biological functions of t

77 A corresponding decrease in Nrf2-DNA-binding activity and a general decrease in Nrf2-targ

78 screen; the top hit compounds inhibited its DNA-binding activity and also M. tuberculosis growth in

79 tive AP-1 cell line, we found that both AP-1 DNA-binding activity and BRG1 reexpression are necessary

80 e use of a Cas9 nuclease mutant that retains DNA-binding activity and can be engineered as a programm

81 e in cAMP responsive element binding protein DNA-binding activity and induction of Yes-associated pro

82 HIF1 recovered from exosomes retains DNA-binding activity and is transcriptionally active in

83 (p.Arg507His and p.Arg377Trp) reduce FAN1's DNA-binding activity and its capacity to rescue mitomyci

84 oprecipitation assays showed inhibited Stat3 DNA-binding activity and recruitment at CyclinD1 and c-M

85 MP-2 treatments, resulting in elevated Stat3 DNA-binding activity and recruitment on CyclinD1 and c-M

86 ral approach for the laboratory evolution of DNA-binding activity and specificity.

87 ) dioxygenase Ofd protein regulates both the DNA-binding activity and the degradation of the hypoxia

88 (C/EBP) beta was activated by LPS (increased DNA binding activity), and played a key role in LPS-indu

89 with LPS or TNF led to the phosphorylation, DNA binding activity, and chemokine promoter association

90 in Nrf2 protein, transcript expression, Nrf2-DNA binding activity, and expression of its transcriptio

91 Tetrameric BlcR(F147A) retained DNA binding activity, and importantly, this activity was

92 m in vitro resulted in a defect in Mlh1-Pms1 DNA binding activity, and in vivo proteolytic cleavage r

93 p65 phosphorylation, nuclear translocation, DNA binding activity, and recruitment to the MCP-1 promo

94 p65 phosphorylation, nuclear translocation, DNA binding activity, and recruitment to the MCP-1 promo

95 The L1 protein has DNA binding activity, and the L2 protein has multiple do

96 had increased HIF-1alpha mRNA, protein, and DNA-binding activity, and alcohol feeding in HIF1dPA mic

97 Balpha), the translocation of p65, NF-kappaB DNA-binding activity, and its transcription activity.

98 In Aiptasia, NF-kappaB protein levels, DNA-binding activity, and tissue expression increase whe

99 fective inhibitors of STAT3 phosphorylation, DNA-binding activity, and transactivation in vitro, lead

100 ge numbers of common target genes, but their DNA-binding activities are blocked by the gibberellin-in

101 .8-fold; both, p < 0.05) and increased GATA4 DNA binding activity as indicated by ELISA and by chroma

102 everse the IkappaB reduction and inhibit the DNA binding activity as well as nuclear translocation of

103 Trim28 depletion increased E2F3 and E2F4 DNA binding activity, as measured by chromatin-immunopre

104 quinolinone inhibitor 1 (FQI1), inhibits LSF DNA-binding activity both in vitro, as determined by ele

105 p65 nuclear translocation and attenuates its DNA binding activity but has no effect on upstream prote

106 These proteins lack intrinsic DNA-binding activity but are recruited to specific genom

107 apsilosis Est3 alone exhibits no appreciable DNA-binding activity, but can be crosslinked to telomeri

108 were found to have human IgG Fcgamma- and/or DNA-binding activity, but only TspB derivatives containi

109 ric form binds to NF-kappaB and enhances its DNA binding activity by directly reducing the cysteines

110 els were measured by immunoblot, STAT3-TGFB1 DNA-binding activity by chromatin immunoprecipitation, a

111 equired neither promoter vacancy nor loss of DNA-binding activity by Irr.

112 RORalpha inhibited E2F1 acetylation and its DNA-binding activity by recruiting histone deacetylase 1

113 Loss of Ikaros DNA-binding activity caused a local increase in chromati

114 of IkappaBalpha and inhibition of NF-kappaB DNA binding activity, caused by the nuclear IkappaBalpha

115 xamined the structural biochemistry of RPA's DNA-binding activity, combining small-angle X-ray and ne

116 estingly, mutations in FANCI that impair its DNA binding activity compromise DNA-stimulated FANCD2 mo

117 The TF DNA-binding activity data set highlights the importance

118 egulates Rgt1 function not by modulating its DNA-binding activity directly but by functionally antago

119 ding terminal inverted repeat (TIR) specific DNA-binding activity, DNA cleavage activity, albeit unco

120 which were attributed to impaired PPARalpha DNA binding activity due to reduced FABP1 protein levels

121 ithin the Runt domain of RUNX3 disrupts RUNX DNA binding activity during mitotic entry to facilitate

122 Although it does not have direct DNA-binding activity, EBNA3C plays a central role in the

123 that phosphorylation-dependent regulation of DNA binding activity evolved as a tunable mechanism to c

124 les, showed a 1.6-fold increase in NF-kappaB DNA binding activity following ECs.

125 2+)-dependent G protein, XLG2, promotes RTV1 DNA binding activity for a subset of floral integrator g

126 protein, mRNA, and transcription factor (TF) DNA-binding activity for mouse liver tissues collected f

127 DNA-binding activity from a single domain is sufficient

128 pendent on the RUNX1 interaction but not the DNA-binding activity harbored within the PBX1 homeodomai

129 ified human Mre11-W243R retains nuclease and DNA binding activities in vitro.

130 sary for redox regulation and enhancement of DNA binding activity in all three proteins.

131 NF-kappaB reporter, and increased NF-kappaB DNA binding activity in cultured neonatal rat ventricula

132 ranscription factor HSF1 mRNA expression and DNA binding activity in primary human monocytes and muri

133 er, how QslA binds to LasR and regulates its DNA binding activity in QS remains elusive.

134 mmunoprecipitation, and reduced TonEBP/NFAT5 DNA binding activity in the renal inner medulla.

135 erial RecO protein displays a zinc-dependent DNA binding activity in vitro and accelerates the anneal

136 Here we show that MDM2 inhibits p53 DNA binding activity in vitro and in vivo.

137 horylation of YY1 at this site abolishes its DNA binding activity in vitro and in vivo.

138 is Rex, we purified EF2638 and evaluated its DNA binding activity in vitro.

139 erine residues and negatively regulates NRF1 DNA binding activity in vitro.

140 en oxidized and reduced cluster controls its DNA binding activity in vitro.

141 Altogether, we define novel DNA-binding activity in a conserved family of transcript

142 IF-1alpha messenger RNA (mRNA), protein, and DNA-binding activity in alcohol-fed mice compared with c

143 ts, Nrf2 translocation into nuclei, and Nrf2 DNA-binding activity in association with increased p62 p

144 bited constitutive STAT3 phosphorylation and DNA-binding activity in human breast cancer, MDA-MB-231

145 lpha and block p65 nuclear translocation and DNA-binding activity in lung tissues from OVA-challenged

146 transcriptional repressor that modulates its DNA-binding activity in response to NADH/NAD(+) ratio, h

147 We found that REDD1 ablation enhances Nrf2 DNA-binding activity in the retina and that the suppress

148 Both inhibitors blocked STAT3 DNA-binding activity in vitro and in human glioma, breas

149 YqjI binding to nickel or iron reduces YqjI DNA-binding activity in vitro.

150 nscription factor, whose transcriptional and DNA-binding activities increased in MDDCs upon exposure

151 Cohesin's DNA binding activity is also promoted by the Eco1 acetyl

152 A non-sequence-specific DNA binding activity is also required for formation of t

153 in response to proteotoxic stress, and HSF1 DNA binding activity is elevated in cycling cells as com

154 tes, diphosphates and triphosphates, and its DNA binding activity is inhibited by triphosphates and d

155 hat in homologous proteins suggests that its DNA binding activity is regulated via a conformational c

156 This DNA binding activity is very poorly understood.

157 ence of the PARP1 protein with uncompromised DNA-binding activities is required for PARPi-induced inn

158 This bHLH DNA-binding activity is abolished if the C-terminal ACT

159 Bacteria possess transcription factors whose DNA-binding activity is altered upon binding to specific

160 ng frequencies, indicating that the telomere DNA-binding activity is critical for TbTRF's role in VSG

161 Lastly, we provide evidence that ComW's DNA-binding activity is important for transformation in

162 e sensitive to redox conditions, since their DNA-binding activity is inhibited after incubation with

163 mechanism of cell cycle regulation, in which DNA-binding activity is intimately linked to the action

164 nits and demonstrate that high-affinity Teb1 DNA-binding activity is necessary and sufficient for cel

165 Our findings show that even though UAF1's DNA-binding activity is redundant with that of RAD51AP1

166 d knockin approaches show that enhanced JunD DNA-binding activity is required for increased expressio

167 Finally, we show that CIITA, which lacks DNA binding activity, is recruited to muscle-specific pr

168 In addition to DNA binding activity, it was critical that specific CpG

169 on the lagging strand daughter DNA, but its DNA binding activity mediated loading of Exo1 onto ssDNA

170 ocalized in the nucleus and showed increased DNA-binding activity, no change in the expression levels

171 anslated regions neither interfered with p53 DNA binding activity nor p53-mediated promoter transacti

172 ion in the N terminus of BRCA2 that exhibits DNA binding activity (NTD) and provide evidence for NTD

173 hibitor curcumin reverses the increased JunD DNA-binding activity observed in the absence of Nfe2.

174 re, we show that variant PRC1 complexes with DNA-binding activities occupy target sites independently

175 acids are promising leads for suppression of DNA binding activities of B-ZIP and B-HLH-ZIP transcript

176 g LPS-/IgG immune complexes-induced ALI, the DNA binding activities of C/EBPgamma are obviously reduc

177 ular evidence that the cell cycle arrest and DNA binding activities of IE2 appear to be responsible f

178 The amounts and DNA binding activities of NFI proteins were similar in i

179 However, NaBu did not alter the DNA binding activities of Sp proteins or their expressio

180 r mechanism by which the 5mC hydroxylase and DNA binding activities of Tet3 cooperate to control targ

181 duced by inactivation of the translocase and DNA binding activities of the FANCM/MHF complex.

182 ubtilis, a model Gram-positive organism, the DNA binding activity of CtsR is regulated by McsAB-media

183 , disrupting TGFbeta signaling decreased the DNA binding activity of DNA methyltransferase DNMT1, sug

184 cleotide exchange predominantly regulate the DNA binding activity of DnaA and that those with low rat

185 Furthermore, the DNA binding activity of DnaD is redundant for this filam

186 Id2 inhibits the DNA binding activity of E proteins, whereas ankyrin-repe

187 MED25 also stimulates the in vitro DNA binding activity of ETV4 by relieving autoinhibition

188 The DNA binding activity of full-length SaeR could be restor

189 Here, we characterize the DNA binding activity of Hox transcription factor complex

190 In aging cells, the DNA binding activity of HSF1 deteriorates correlating wi

191 housands of rare alleles likely to alter the DNA binding activity of human sequence-specific TFs.

192 A(98-239) is a suitable model to examine the DNA binding activity of human XPA.

193 uced apoptotic cell death and suppressed the DNA binding activity of NF-kappaB in a concentration dep

194 n of p-Akt, VEGF, Ang-1, Bcl-2, survivin and DNA binding activity of NF-kappaB were observed in the G

195 Trx is also known to activate the DNA binding activity of NF-kappaB, an important transcri

196 ity shift assay revealed that PMA stimulated DNA binding activity of NF-kappaB.

197 vation, NF-kappaB nuclear translocation, and DNA binding activity of NF-kappaB.

198 e pattern controlled by the rapidly evolving DNA binding activity of PRDM9.

199 The DNA binding activity of PrgX has additional indirect reg

200 n seed formation is tightly regulated by the DNA binding activity of protagonist basic leucine zipper

201 The DNA binding activity of RbkR was stimulated by CTP and s

202 ly expressed had the general single-stranded DNA binding activity of RPA complexes, unlike the telome

203 manner and that GTP-bound XLG2 promotes the DNA binding activity of RTV1.

204 ector factor 1, which is able to enhance the DNA binding activity of several transcription factors th

205 ort, we have developed assays to measure the DNA binding activity of Shelterin complexes in human cel

206 tion, low oxygen increases the stability and DNA binding activity of Sre1N.

207 We show that IgG IC-induced DNA binding activity of Stat3 in the lung was significan

208 tion initiation, it can be expected that the DNA binding activity of the mitochondrial transcription

209 It is generally accepted that global DNA binding activity of the NF-kappaB avian reticuloendo

210 s are enriched at hotspots determined by the DNA binding activity of the rapidly evolving zinc finger

211 We show that the DNA binding activity of the Soj dimer is required both f

212 s(203) disulfide bond appears to disrupt the DNA binding activity of the transcription factor.

213 Surprisingly, we find that the DNA binding activity of the UAF1-associated protein RAD5

214 vation, telomeres deploy the single-stranded DNA binding activity of TPP1/POT1a.

215 Taken together, inhibition of the DNA binding activity of transcriptional repressor OCT-1

216 the C-terminal WRKY domain and stimulate the DNA binding activity of WRKY33.

217 The structures and DNA-binding activities of basal NF-kappaB proteins resem

218 Here, we reveal how distinct DNA-binding activities of Hop2-Mnd1 mediate the stabiliz

219 cell-type specific up/down-modulation of the DNA-binding activities of NF-kappaB, AP-1, and multiple

220 enylephrine stimulated the Ca(2+) -dependent DNA-binding activities of NFAT2, NFAT4, and Sp1 (but not

221 n of partition complexes requires ATPase and DNA-binding activities of ParA.

222 bolites, F-1-P and F-6-P, could modulate the DNA-binding activities of the lactose repressor.

223 anism by which ligand binding attenuates the DNA-binding activities of these proteins.

224 The DNA-binding activity of AP-1 increased after stretch sti

225 CHOP10 by arsenic is associated with reduced DNA-binding activity of CCAAT/enhancer-binding protein b

226 e information about the domain structure and DNA-binding activity of D5, the poxvirus helicase-primas

227 creased the level of p53, independent of the DNA-binding activity of Dmp1.

228 ICL-induced RPA foci formation requires the DNA-binding activity of FAAP24 but not the DNA transloca

229 tion mechanism that allosterically regulates DNA-binding activity of GT2-LIKE 1 (GTL1), a transrepres

230 Enhanced DNA-binding activity of heat shock transcription factor

231 by CBP has been implicated in inhibiting the DNA-binding activity of HSF.

232 To better understand the DNA-binding activity of human XPA in NER, we used NMR to

233 In functional assays, DNA-binding activity of I184M was reduced, resulting in

234 Correspondingly, P4 diminished the DNA-binding activity of NF-kappaB and the transcription

235 ls of p65 with corresponding increase in the DNA-binding activity of NF-kappaB as detected by electro

236 on of nuclear factor-kappaB (NF-kappaB), and DNA-binding activity of NF-kappaB compared with WT.

237 DNA-binding activity of NF-kappaB was higher in HSF-1(-/

238 AMF overexpression led to an increase in the DNA-binding activity of NF-kappaB, which, in turn, led t

239 f2 and its binding with Keap1, but decreased DNA-binding activity of Nrf2 and also its binding at the

240 Despite its lack of enzymatic activity, DNA-binding activity of NrtR is antagonized by the effec

241 tion domain in p53, which likely weakens the DNA-binding activity of p53 to the MIC-1 promoter.

242 the ParB/parS partition complex requires the DNA-binding activity of ParA, which transiently tethers

243 lignancy, using compounds that stimulate the DNA-binding activity of RAD51 to promote cancer cell dea

244 However, whereas the DNA-binding activity of RAD51AP1 has been shown to be im

245 is regulate the phosphorylation level or the DNA-binding activity of response regulators such as Spo0

246 gic inhibition of NF-kappaB signaling or the DNA-binding activity of RPA1 abrogates the pro-survival

247 ging readouts allowed us to characterize the DNA-binding activity of SaCas9 and to optimize its sgRNA

248 APE1's redox activity stimulates the DNA-binding activity of several transcription factors, i

249 TSA treatment did not alter the DNA-binding activity of Sp1 toward the P-Rex1 promoter;

250 However, DLX4 also bound and inhibited DNA-binding activity of Sp1.

251 y binds directly to the DBD and inhibits the DNA-binding activity of STAT3 both in vitro and in situ

252 hese tyrosine residues inhibits the promoter DNA-binding activity of T-bet.

253 These data demonstrate that the DNA-binding activity of Tal1 is not required to cooperat

254 dicating that the L1 loop contributes to the DNA-binding activity of TEAD.

255 Two block the DNA-binding activity of the CRISPR-Cas complex, yet do t

256 to physically interact with and modulate the DNA-binding activity of the major mitochondrial nucleoid

257 play complementary roles in determining the DNA-binding activity of the NF-kappaB proteins encoded b

258 We show that the DNA-binding activity of the S. globisporus orthologue of

259 lock imparted by Tbf1 can be overcome by the DNA-binding activity of the single-stranded DNA-binding

260 al OB fold of STN1, but does not require the DNA-binding activity of this domain.

261 omain protein (PRH/Hhex) by CK2 inhibits the DNA-binding activity of this transcription factor.

262 This biochemical analysis revealed that the DNA-binding activity of UAF1 is indispensable for enhanc

263 A binding, had only a moderate effect on the DNA-binding activity of XPA.

264 is there a metal preference for conferral of DNA-binding activity on the purified proteins.

265 subunits are required for sequence-specific DNA binding activity, only DmSNAP190 possesses a canonic

266 Disruption of E2F8's DNA binding activity phenocopied the effects of an E2f8

267 , or cAMP responsive element binding protein DNA-binding activity prevented the proliferative effects

268 opy, the structural basis for regulating the DNA-binding activity remains unknown.

269 een reported, the structural basis for XPA's DNA-binding activity remains unknown.

270 A well-characterized sequence-specific DNA binding activity resides in the E1 DBD and is used t

271 Our investigations of the DNA-binding activity reveal that although the formation

272 Unlike TBP, TRF2 lacks sequence-specific DNA binding activity, so the mechanism by which TRF2 is

273 Furthermore, through regions involved in DNA-binding activity, Sox2 and TLX physically interact t

274 compound appreciably affected STAT1 or STAT5 DNA-binding activities, STAT3-independent gene transcrip

275 teracted and restored the pM-inhibited Stat3 DNA-binding activity, suggesting IL-6/Stat3 signaling su

276 The E1 protein encodes two DNA binding activities that are required for initiation

277 hich might then reduce significantly the TR4 DNA binding activity that resulted in the suppression of

278 inactivation causes changes in CREB and p65 DNA-binding activity that favors decreased proinflammato

279 als of pUL34 overlap the domain required for DNA-binding activity, the two regions are separable by p

280 induces target-proximal regeneration of ParA DNA binding activity to enforce processive and pole-dire

281 getative viral DNA replication, restores the DNA binding activity to phosphorylated E1.

282 Here we show that Nfe2 represses JunD DNA-binding activity to the Gcm1 promoter during syncyti

283 ParA also has a site-specific DNA-binding activity to the par operator (parOP), which

284 1 enhances nuclear factor kappaB (NF-kappaB) DNA binding activity together with mutant p53 and induce

285 -driven phosphorylation of CcpA inhibits its DNA binding activity toward its regulon in S. aureus, re

286 anscription factors, we abrogated its global DNA-binding activity using a dominant-negative FOS pepti

287 lity shift assays demonstrated that the CcpA DNA binding activity was completely abrogated for the ph

288 of the C216S mutant, a moderate increase in DNA binding activity was observed.

289 onsequently, accessibility of CNS-1 to GATA3 DNA binding activity was reduced in response to IFN-alph

290 omain function of VP1 mutants that lacked B3 DNA binding activity was sufficient for complementation

291 mbryonic fibroblasts (MEFs), and overall Egr DNA-binding activity was suppressed in Arf-deficient but

292 osphorylation of CREB at serine 133 and CREB DNA binding activity were abrogated in cells treated wit

293 lytic processing p105 and p100 and NF-kappaB DNA binding activity were elevated in these cells.

294 , but not its transcriptional repression and DNA binding activities, were required for c-Myc upregula

295 ression of Pin1 increases endogenous ERalpha DNA binding activity when activated by estrogen but not

296 of Pif1 stimulated its helicase, ATPase, and DNA-binding activities, whereas maintaining its substrat

297 st individuals have unique repertoires of TF DNA binding activities, which may contribute to phenotyp

298 phorylation, its transcription activity, and DNA binding activity, which suggests that TGR5 antagoniz

299 la mutation leads to a ~60-fold reduction of DNA binding activity while a Cys to Ser substitution at

300 mitate-induced inflammation and p65-NFkappaB DNA binding activity, while C/EBPbeta overexpression ind