ライフサイエンスコーパス: DNA

1 DNA and cDNA 16S rRNA gene profiling demonstrated that t

2 DNA binding correlates with nucleotide occupancy: five M

3 DNA double-strand breaks (DSB) are the most deleterious

4 DNA methylation is a major silencing mechanism of transp

5 DNA repair GAs are relatively frequent in GBC and associ

6 DNA was extracted and sequenced.

7 DNA-encoded small molecule libraries (DELs) have enabled

8 , enhanced phosphorylation (Ser73), and AP-1/DNA-binding in response to S. mansoni infection.

9 diesterase 2 (TDP2) reverses Topoisomerase 2 DNA-protein crosslinks (TOP2-DPCs) in a direct-reversal

10 A 2D DNA sheet could be modularized into connected parts (e.g

11 Herein, we rationally design a DNA-based artificial molecular signaling system that use

12 -subunit origin recognition complex (ORC), a DNA replication initiator, defines the localization of t

13 To repair a DNA double-strand break by homologous recombination, 5'-

14 of nucleic acid detection for low-abundance DNA biomarkers.

15 the allosteric mechanism of nickel-activated DNA binding by HpNikR is driven by conformational select

16 ed at nucleotide 991, creating an additional DNA substrate for the unessential but highly conserved A

17 The nucleolytic resection of DSB-adjacent DNA is a key step in meiotic DSB repair, but this proces

18 NAD(+) levels also affect DNA repair capacity as NAD(+) is a substrate for PARP-en

19 tion in PCR-based diagnostics, high-affinity DNA aptamer generation, site-specific labeling of RNAs,

20 etics of recognition and repair of alkylated DNA by AlkB.

21 DNA into nucleosomes profoundly affects all DNA-related processes in eukaryotes.

22 lations of nanofibers formed using analogous DNA approaches, gammaPNA structures appear to form bundl

23 tance (drug extrusion, drug degradation, and DNA damage repair) and using rate constants of these rea

24 esponse protein regulated in development and DNA damage 1 (REDD1) is necessary for the development of

25 osensors (e.g. enzymatic, immunosensors, and DNA-based).

26 n X-chromosome inactivation, imprinting, and DNA damage repair, and mutations in SMCHD1 can cause fac

27 PBRM1, BAP1 and SETD2), DNA methylation and DNA damage repair, all of which have been associated wit

28 histone post-translational modifications and DNA methylation.

29 atin remodeler-associated modifications, and DNA methylation) that contribute to relapse to cocaine,

30 on treatments that target RNA processing and DNA repair pathways simultaneously as effective cancer t

31 , we explore the transcriptional profile and DNA replication timing (RT) under mild replication stres

32 zymes responsible for regulating protein and DNA modifications are targets of current cancer therapie

33 ions between the globular domains of M/R and DNA, we observe transient interactions between DNA subst

34 ription-coupled homologous recombination and DNA replication restart.

35 -toward the ultimate goal of forming RNA and DNA by polymerization.

36 omatid cohesion, chromosome segregation, and DNA repair.

37 ly, H. pylori-induced replication stress and DNA damage depend on the presence of co-transcriptional

38 ggesting the modulation of transcription and DNA damage that may be mediated by the action of HDAC an

39 Levels of anti-DNA antibodies can fluctuate widely, unlike those of ant

40 -7, in inactive double hexameric form around DNA.

41 As DNA nicking by MutLgamma depends on its co-factors, the

42 es, there was a reduction in cell-associated DNA load, intact proviral DNA levels, and in inducible S

43 protecting cells from replication-associated DNA damage and promoting cellular recovery.

44 asis, affects ATP production, and attenuates DNA repair.

45 Background DNA prevented any diagnosis in cases analyzed without mi

46 mber of studies have reported that bacterial DNA methylation has important functions beyond the roles

47 A, we observe transient interactions between DNA substrates and the Rad50 coiled coils.

48 recombination intermediates may drive biased DNA cleavage.

49 rements of full length p53 tetramers binding DNA reveal the parameters that define the stability of p

50 e-boronic acid (An-BA) probe to a biomimetic DNA scaffold and consequently, to use the unique photoph

51 ed by biallelic disruption of the WRN or BLM DNA helicases respectively.

52 of Cd and smoking exposures with human blood DNA methylation (DNAm) profiles.

53 th aberrant interphase replication of bridge DNA.

54 Cytosine DNA bases can be methylated by DNA methyltransferases and subsequently oxidized by TET

55 t mediates stable binding to a non-canonical DNA motif.

56 Chemotherapy and irradiation cause DNA damage to hematopoietic stem cells (HSCs), leading t

57 metabolism or other perturbations that cause DNA damage.

58 Cellular DNA can be damaged by spontaneous hydrolysis, reactive o

59 factor X, or MAX for short, to bind certain DNA recognition motifs in gene promoters that regulate g

60 etion of the Trp53 tumor suppressor or Chek2 DNA damage checkpoint kinase rescued Smc5 cKO neurodevel

61 l roles in base excision repair and ATR-Chk1 DNA damage response (DDR) pathways, it remains unknown h

62 analysis was conducted using six chloroplast DNA sequences from leaf material from across the BI and

63 titor, either in a plasmid or in chromosomal DNA, containing the same binding site but with a differe

64 is ~1,100 times shorter than the chromosomal DNA.

65 abolished and p53 binds initially to cognate DNA sites as a dimer.

66 The Cys2His2 zinc finger is the most common DNA-binding domain expanding in metazoans since the fung

67 at small changes outside of highly conserved DNA-binding regions can lead to profound changes in prot

68 clinical assays lack patient-matched control DNA and additional analysis is needed to distinguish som

69 Cytosine DNA bases can be methylated by DNA methyltransferases an

70 longevity and enormous information density, DNA is considered a promising data storage medium.

71 cellular NAD(+) content and NAD(+)-dependent DNA repair capacity.

72 d thus activates the TMEM173/STING-dependent DNA sensor pathway, which results in macrophage infiltra

73 ication arrest, allowing replication despite DNA damage.

74 ide unprecedented insight into how different DNA sequences select distinct compositions and configura

75 human cohort data have revealed differential DNA methylation signatures in proxy tissues that are ass

76 Direct DNA repair gene GAs were identified in 109 patients (14.

77 fering RNAs (siRNAs) that guide RNA-directed DNA methylation.

78 ented by the presence or absence of distinct DNA strands, called molecular bits (molbits).

79 mes are implicated in the control of diverse DNA-templated processes including gene expression.

80 is based on standardized recombinase-driven DNA scaffolds expressing different genes according to th

81 Shot loss leads to double-strand break (DSB) DNA damage, and the apoptotic response is exacerbated by

82 nism essential for replisome assembly during DNA replication initiation that is vulnerable to inhibit

83 with the natural A, T, G and C bases during DNA synthesis, which allows for labeling of replicating

84 protect 3D genome structure integrity during DNA damage repair.

85 frequently dissociate from replisomes during DNA replication in vivo.

86 are expected to pose a problem to efficient DNA bubble migration.

87 argc1a promoter had a fetal origin; elevated DNA methylation was also detected in neonatal BAT and br

88 tructures, which makes accessing the encased DNA strands difficult, or chemical modification, such as

89 clease domain mutations in the gene encoding DNA polymerase epsilon (POLE) have incredibly high mutat

90 d by the idiosyncratic needs of the encoding DNA tag relegating DEL compatible chemistry to dilute aq

91 Our data show that endogenous DNA gap repair in E coli supports efficient multiplex si

92 Engineered DNA substrates that stabilize a reaction intermediate by

93 fe of Nkx3.1 reduces proliferation, enhances DNA end-labeling, and protects from DNA damage, ultimate

94 tion, activating antioxidants, and enhancing DNA repair.

95 Cs) are generally characterized by excellent DNA surveillance and repair, resulting in one of the low

96 asures of mRNA expression, miRNA expression, DNA methylation, and histone acetylation from ASD and co

97 sformed between two conformations with a few DNA "trigger" strands.

98 various DNA motifs are mediated by its flat DNA-binding surface, which is centered on a short loop s

99 tegy for achieving a sensitive biosensor for DNA detection and diagnostic applications.

100 likely helps to position Bax1 at the forked DNA allowing the nuclease domain to incise one arm of th

101 ole-genome bisulfite sequencing of cell free DNA (cfDNA) and of matched metastatic tumor biopsies fro

102 enhances DNA end-labeling, and protects from DNA damage, ultimately blocking the proneoplastic effect

103 ics of biological and physical systems, from DNA to turbulent plasmas, as well as in climbing, weavin

104 e circulation by both mRNA-based and genomic DNA-based sequencing.

105 ree different gRNAs targeting HEK293 genomic DNA, resulting in a set of 55 high-confidence gRNA cleav

106 The organization of genomic DNA into nucleosomes profoundly affects all DNA-related

107 s of maternal SMCHD1 does not alter germline DNA methylation imprints pre-implantation or later in ge

108 e barrier to ensure safeguarding of germline DNA from environmental insults.

109 of Dppa3 facilitated the emergence of global DNA demethylation in mammals.

110 posed sensor was successfully applied in HBV DNA detection in sera from patients without any amplific

111 This perspective will highlight DNA double-strand break (DSB) repair pathways in human c

112 The primary endpoint was total HIV DNA isolated from peripheral blood CD4(+) T-cells at wee

113 ak (DSB) repair pathways in human cells, how DNA repair failures can lead to human disease, and how P

114 on even when viral load exceeded 1 x 107 HSV DNA copies, and surges in granzyme B and IFN-gamma occur

115 Human DNA methylation data have been used to develop biomarker

116 ging because of low bacterial and high human DNA abundances.

117 Interestingly, human DNA polymerase eta (poleta) proficiently incorporates dG

118 chanistically, 6-4PPs, but not CPDs, impeded DNA replication across the genome as revealed by microfl

119 of endonucleases throughout the biosphere in DNA restriction, repair, and homing.

120 more frequently in isolates with defects in DNA mismatch repair that confer an elevated mutation rat

121 tation information, with new developments in DNA methylation classification.

122 nally, exposed fish exhibited differences in DNA methylation in selected genes, across all three gene

123 temperatures have measurable differences in DNA, RNA and protein composition that allow OGT predicti

124 icantly contribute to genetic instability in DNA mismatch repair-defective human tumors.

125 e 1 (PARP-1) is a nuclear enzyme involved in DNA repair and transcription regulation, among other pro

126 ription of the MCM6 gene that is involved in DNA replication by directly binding to specific motifs w

127 t pathways controlled by (pp)pGpp, including DNA replication, transcription, nucleotide synthesis, ri

128 s in diverse biological processes, including DNA damage repair (Fanconi anemia), telomere maintenance

129 , and other enzymes that modify incompatible DNA ends to allow their ligation.

130 Increased DNA methylation in Ppargc1a promoter had a fetal origin;

131 ed another mechanism wherein 5-AzadC induced DNA damage, which then resulted in enhanced occupancy of

132 The measurement of UV-induced DNA damage as a dosimeter of exposure and predictor of s

133 DNA, however, in the presence of UV-induced DNA lesions these complexes stall.

134 from IECs increases markers of inflammation, DNA damage, and cell proliferation and increases colorec

135 Interestingly, DNA flanking the RNA-5' side of R-loops is not intrinsic

136 event incorporation of N6-methyl-(d)ATP into DNA and RNA.

137 unity, and in anticancer therapies involving DNA damage agents.

138 cer and anti-obesity drugs by inhibiting its DNA-binding activities.

139 posi's sarcoma-associated herpesvirus (KSHV) DNA in blood and increased antibody titres may indicate

140 its efficiency for the introduction of large DNA sequences in zygotes is low.

141 air with unique DNA handles in order to link DNA origami nanostructures bearing complementary strands

142 Our study links DNA methylation to disease endpoints via intermediate pr

143 RSE) is characterized by the capture of long DNA fragments (15-20 kb) by magnetic beads, after enzyma

144 uring neurodevelopment, but it also mediates DNA damage repair essential to proliferating neural prog

145 rchical strand-displacement reaction on meta-DNA to transfer the dynamic features of DNA into the met

146 er the dynamic features of DNA into the meta-DNA.

147 alpha-1 antitrypsin concentrations.Methods: DNA samples from 1,693 non-Hispanic white individuals, 3

148 tant pedigree computation, and mitochondrial DNA (mtDNA) copy number inference.

149 w bronchoalveolar lavage fluid mitochondrial DNA and more severe disease.

150 ed by CGAS or STING knockdown, mitochondrial DNA depletion or mitochondrial outer membrane permeabili

151 ng the way to cost-effective single-molecule DNA sequencing, capable of handling widely varying GC-bi

152 tion distinct from that of surrounding mouse DNA.

153 validation experiments employed mycobacteria DNA, either extracted or intracellular.

154 structures of nucleosomes containing native DNA sequences.

155 s nuclease (Nuc)-mediated degradation of NET DNA.

156 4) structures are four-stranded noncanonical DNA structures enriched at telomeres and oncogenes' prom

157 s reveal that histone modifications, but not DNA methylation, underlie exon-specific transcription of

158 s similar Dnmt3b isoforms facilitate de novo DNA methylation during embryonic development and in soma

159 These days, enormous amounts of DNA sequence and other omics data are generated.

160 Moreover, analysis of DNA from 79 subjects showed sequence variations in the l

161 We perform a comprehensive analysis of DNA synthesis at all STR permutations and interrogate th

162 dification, such as covalent crosslinking of DNA strands.

163 Deletion of DNA-PK or PTEN, or inhibition of DNA-PK sensitized recov

164 WS) and Bloom Syndrome (BS) are disorders of DNA damage repair caused by biallelic disruption of the

165 meta-DNA to transfer the dynamic features of DNA into the meta-DNA.

166 halan) activity, as measured by formation of DNA adducts.

167 Here, we investigate the impact of DNA damage response and repair on 3D genome folding usin

168 Deletion of DNA-PK or PTEN, or inhibition of DNA-PK sensitized recovering BLBCs to AZD1775 by abrogat

169 This is followed by a further injection of DNA as a competitor, either in a plasmid or in chromosom

170 DNA can be exploited to tune the kinetics of DNA translocation.

171 ion (unlooping) rates (kloop and kunloop) of DNA with sticky ends over three helical periods (100-130

172 Local levels of DNA methylation result from opposing enzymatic activitie

173 us sequencing reads, an additional 8.9 Mb of DNA sequence was mappable, variant calling achieved a hi

174 Furthermore, 2'F modifications of DNA NANPs significantly enhances RIG-I mediated producti

175 These results define the repair pathways of DNA interstrand crosslinks caused by an endogenous and a

176 AZD1775 induced phosphorylation of DNA-PK, protecting cells from replication-associated DNA

177 The presence of DNA damage increases the frequency of pausing.

178 se mitochondrial function trigger release of DNA damaging reactive oxygen species.

179 The Pif1-dependent stimulation of DNA synthesis across strong protein barriers may be bene

180 G4) is a noncanonical secondary structure of DNA or RNA which can enhance or repress gene expression,

181 s a resource to facilitate future studies of DNA demethylation in pathogenesis and the development of

182 The enzymatic synthesis of DNA is a promising alternative, but thus far has not bee

183 reaks (DSB) are the most deleterious type of DNA damage.

184 mportant hub for processing various types of DNA damage.

185 rotein PC4, in complex with a full PS 2'-OMe DNA gapmer ASO.

186 highly motile ATL and ATL-UvrA complexes on DNA at the molecular level.

187 ides a way to study the effect of defects on DNA supercoiling and the dynamics of supercoiling in mol

188 reveals they bind to and randomly diffuse on DNA, however, in the presence of UV-induced DNA lesions

189 letion of the conserved helicase PIF1 and/or DNA damage checkpoint-mediator RAD9.

190 independent of the nucleic acid type (RNA or DNA), its strandedness (single or double), and its seque

191 in controlling the formation of higher-order DNA secondary structures to regulate transcription beyon

192 reactive oxygen species (ROS), which oxidize DNA and other cellular components.

193 study unravels a role of endogenous oxidized DNA bases and APE1 in controlling the formation of highe

194 SMC5/6 depletion triggers a CHEK2-p53 DNA damage response, as concomitant deletion of the Trp5

195 parameters that define the stability of p53/DNA complexes, and provide insight into the pathways by

196 lasma circulating tumor human papillomavirus DNA (ctHPVDNA) is a sensitive and specific biomarker of

197 ing at poly(ADP-ribose) polymerase 1 (PARP1)-DNA complexes trapped by PARP inhibitors, thereby promot

198 d off to the side of the catalytic Pol3-PCNA-DNA axis.

199 neurotrophic factor (BDNF) and total percent DNA methylation of Th and Bdnf genes in the frontal cort

200 reveal that excessive placental DNA damage in murine models for Cornelia de Lange syndro

201 nanonucleases, able to cleave pBR322 plasmid DNA with the highest efficiency reported so far for cata

202 nucleotide was in the first coding position, DNA synthesis fidelity was similar to that observed with

203 gnition, some fundamental aspects of protein-DNA binding remain poorly understood(1,2).

204 in cell-associated DNA load, intact proviral DNA levels, and in inducible SIV reservoir in lymph node

205 Compared to double stranded DNA, PX DNA has dramatically enhanced (sometimes >1000 fold) res

206 enzymatic method to clean up and reconfigure DNA-origami structures.

207 ibition of an analog-sensitive CDK12 reduces DNA damage repair gene expression, but selective inhibit

208 By regulating DNA access for transcription, replication, DNA repair, a

209 lows for labeling of replicating or repaired DNA.

210 ding transcribing, replicating and repairing DNA.

211 el-miR-71-5p and bma-lin-4, and O-150 repeat DNA were assessed.

212 g DNA access for transcription, replication, DNA repair, and epigenetic modification, chromatin forms

213 how that the response of a model replicative DNA polymerase to variously structured DNA is sufficient

214 e licensed by the loading of the replicative DNA helicase, Mcm2-7, in inactive double hexameric form

215 pendent cohesin removal is needed to restart DNA synthesis at stalled forks and promote survival foll

216 nsferase, DarT(Mtb) ), to mediate reversible DNA ADP-ribosylation (Jankevicius et al., 2016).

217 We show that the phosphorylation of the RNA-DNA binding protein fused in sarcoma (FUS) is higher in

218 nd on the presence of co-transcriptional RNA/DNA hybrids (R-loops) that form in infected cells during

219 nctions along with its cognate toxin Rv0059 (DNA ADP-ribosyl transferase, DarT(Mtb) ), to mediate rev

220 One of these, Rv0060 (DNA ADP-ribosyl glycohydrolase, DarG(Mtb) ), functions a

221 This work shows that V1V2 scaffold DNA priming immunization provides a method to focus immu

222 elling (for example, PBRM1, BAP1 and SETD2), DNA methylation and DNA damage repair, all of which have

223 vs. 11/20 aqueous samples along with shorter DNA fragments.

224 lex that differ based on whether target site DNA is annealed or dynamic.

225 plasma viremia, reduced cell-associated SIV-DNA, and preserved Th17 homeostasis, including at pre-AR

226 that transcription factors bind to specific DNA sequences using a combination of base readout and sh

227 everse-transcribing and single-stranded (ss) DNA viruses.

228 mer competent for non-specific double-strand DNA cleavage.

229 y challenging the notion that lagging-strand DNA polymerases frequently dissociate from replisomes du

230 Compared to double stranded DNA, PX DNA has dramatically enhanced (sometimes >1000 f

231 lusively occupies the strong double-stranded DNA (dsDNA)-binding surface on cGAS and sterically preve

232 division, FtsK translocates double-stranded DNA until both dif recombination sites are placed at mid

233 RNA genome is converted into double-stranded DNA, is that it is slow and non-processive.

234 and reversible compaction of double-stranded DNA.

235 cDmc1 results from its lower single-stranded DNA (ssDNA) affinity, compared to that of ScRad51.

236 that potentially binds with single-stranded DNA (ssDNA) in a manner similar to human PC4, the protot

237 tiate a slow-cycling state following stress (DNA damage, targeted therapy, and aging).

238 multiple factors, including cellular stress, DNA damage and immune surveillance.

239 e mechanisms including the oxidative stress, DNA damage, lysosomal dysfunction, inflammatory cascade,

240 ative DNA polymerase to variously structured DNA is sufficient to predict the complex genomic behavio

241 functions to moderately enhance class-switch DNA recombination (CSR), while decreasing at higher dose

242 The assay was developed with synthetic DNA templates and validated with DNA from two breast can

243 required for packaging of newly synthetized DNA into nucleosomes during the S phase when their expre

244 TAR DNA-binding protein 43 (TDP-43) has emerged as a key pla

245 Insoluble, hyperubiquitylated TAR DNA-binding protein of 43 kDa (TDP-43) in the central ne

246 ged with transposon ends and U-shaped target DNA prior to integration (the target capture complex) an

247 RF2 instead activate an attenuated telomeric DNA damage response that lacks accompanying telomere fus

248 ns of telomeric sequences into non-telomeric DNA.

249 k by homologous recombination, 5'-terminated DNA strands must first be resected to reveal 3'-overhang

250 t a rate approximately 25 times greater than DNA sequence changes and typically have short half-lives

251 Our analyses indicate that DNA methylation patterns associated with the susceptible

252 We discuss this phenomenon and propose that DNA methylation turnover might facilitate key lineage de

253 Cryo-EM reveals that DNAs transported into E-S/E-K compartments are 'clamped'

254 ome ends from inappropriately activating the DNA damage and repair responses.

255 to be endoergic in aqueous solution and the DNA duplexes but slightly exoergic in the polymerase, wi

256 Another motif, DPHK, is in the DNA-binding domain.

257 sequence as the relaxosome, which nicks the DNA strand destined for transfer and couples the nicked

258 rent study, we report that inhibitors of the DNA damage response kinase ATR can significantly potenti

259 -T cells displayed altered expression of the DNA methyltransferase 1 (DNMT1) isoform.

260 Analysis of the DNA polymorphisms revealed that 2347 nonsynonymous SNPs

261 Here, we report a crystal structure of the DNA-binding domain of a model ASO-binding protein PC4, i

262 sequently suggests that the knowledge of the DNA-binding properties of the proteins is in itself not

263 Notably, the expression of the DNA-binding-deficient mutant of NuMA affects chromatin d

264 acent RuvC nuclease and propagates up to the DNA recognition lobe in full-length CRISPR-Cas9.

265 R17 and Q41 interacting exclusively with the DNA backbone.

266 ies on ISG15 functional interaction with the DNA helicase RECQ1, which promotes restart of stalled re

267 duplicate only once in coordination with the DNA replication cycle and have an important role in segr

268 clear shape by directly associating with the DNA.

269 ee arsenic-coordinating cysteines within the DNA-binding domain, distal to the zinc-binding site.

270 e binding to the same consensus motif, their DNA-binding syntax is different, suggesting discriminato

271 In this DNA demethylated context, either deletion of the CTCF bi

272 report that L1 activity triggers FOA through DNA damage-driven apoptosis and the complement system of

273 ce as input to predict binding of protein to DNA, RNA, and other proteins.

274 l studies showed that Rad4, when tethered to DNA, could also open undamaged DNA, suggesting a 'kineti

275 gradation process involved in transcription, DNA repair, and cell division.

276 he initiating steps of conjugative transfer, DNA transfer and replication (Dtr) proteins assemble at

277 owered motors during assembly to translocate DNA into procapsid shells.

278 rag force exerted by flow on a translocating DNA can be exploited to tune the kinetics of DNA translo

279 to evaluate the utility of circulating tumor DNA (ctDNA) genotyping, we compare trial enrollment usin

280 Tyrosyl-DNA phosphodiesterase 2 (TDP2) reverses Topoisomerase 2

281 n tethered to DNA, could also open undamaged DNA, suggesting a 'kinetic gating' mechanism whereby les

282 e a coiled-coil heterodimer pair with unique DNA handles in order to link DNA origami nanostructures

283 A ring-shaped helicase unwinds DNA during chromosome replication in all organisms.

284 MDM2 autoubiquitination and degradation upon DNA damage, whereas S429A substitution protects MDM2 fro

285 design as an approach for generating useful DNA parts.

286 ntial to be highly mutagenic because it uses DNA polymerases, nucleases, and other enzymes that modif

287 The binding of Fpr to various DNA motifs are mediated by its flat DNA-binding surface,

288 ce the effective depth of synthesized vector DNA libraries, thereby raising the discovery cost of nov

289 yme kinetic parameters of cellular and viral DNA and RNA polymerases with respect to cellular levels

290 with a Pyk2 kinase inhibitor increased viral DNA content in keratinocytes that maintain viral episome

291 However, SP-2509 does inhibit viral DNA replication, late gene expression, and virus product

292 on recognition by ATL and directly visualize DNA lesion search by highly motile ATL and ATL-UvrA comp

293 we demonstrate that high-throughput in vitro DNA binding assays coupled with unbiased computational a

294 In vitro DNA-binding experiments and structural prediction show t

295 stage of human NK cell development in which DNA demethylation takes place to allow for active transc

296 onchoscopy to collect epithelial cells whose DNA methylation was measured using the Illumina 450 K pl

297 ities for colloidal crystal engineering with DNA.

298 ubles the number of published syndromes with DNA methylation episignatures and, most significantly, o

299 h synthetic DNA templates and validated with DNA from two breast cancer cell-lines and two patient tu

300 A large region of fission yeast DNA inserted into a mouse chromosome was previously obse