ライフサイエンスコーパス: Descemet

1 Descemet membrane detachment (DMD) is a significant comp

2 Descemet membrane detachment involved the visual axis in

3 Descemet membrane endothelial keratoplasty (DMEK) is a c

4 Descemet membrane endothelial keratoplasty and UT-DSAEK

5 Descemet membrane endothelial keratoplasty cases that us

6 Descemet membrane endothelial keratoplasty cost $392.31

7 Descemet membrane endothelial keratoplasty decreases and

8 Descemet membrane endothelial keratoplasty had superior

9 Descemet membrane endothelial keratoplasty may be furthe

10 Descemet membrane endothelial keratoplasty results in le

11 Descemet membrane endothelial keratoplasty was performed

12 Descemet membrane endothelial keratoplasty.

13 Descemet membrane perforation was observed in 8 eyes (72

14 Descemet membrane rolling behavior showed significant in

15 Descemet membrane ruptures from blast exposure were desc

16 Descemet Stripping Automated Endothelial Keratoplasty (D

17 Descemet stripping automated endothelial keratoplasty (D

18 Descemet stripping automated endothelial keratoplasty af

19 Descemet stripping automated endothelial keratoplasty wi

20 Descemet stripping automated endothelial keratoplasty wi

21 Descemet stripping endothelial keratoplasty.

22 Descemet's membrane (DM) helps maintain phenotype and fu

23 Descemet's membrane detachment has been reported after n

24 Descemet's membrane is markedly thinned.

25 Descemet's membrane supports corneal endothelial cell re

26 Descemet's membrane was formed by a normal anterior band

27 Descemet's membrane was isolated from pig corneas and wa

28 Descemet's membrane with intact endothelium was dissecte

29 Descemet's stripping automated endothelial keratoplasty

30 Descemet's stripping automated endothelial keratoplasty

31 Descemet's stripping endothelial keratoplasty (DSEK) is

32 Descemet's stripping endothelial keratoplasty (DSEK) is

33 Descemet's stripping with automated endothelial keratopl

34 oidal effusion (1), vitreous hemorrhage (3), Descemet detachment (1), and persistent hyphema (2).

35 ould be completed using (a combination of) 4 Descemet graft unfolding techniques: (1) standardized no

36 In Group I, 93 Descemet stripping endothelial keratoplasty (DSEK) (51%)

37 nical feasibility and clinical outcomes of a Descemet membrane endothelial keratoplasty (DMEK) techni

38 of Fuchs endothelial dystrophy (primarily a Descemet membrane disorder), but not in bullous keratopa

39 terface, which may limit visual acuity after Descemet stripping automated endothelial keratoplasty.

40 Best-corrected visual acuity after Descemet's stripping endothelial keratoplasty (DSEK) ran

41 strategies that improve graft adhesion after Descemet membrane endothelial keratoplasty (DMEK) to red

42 nical outcome of 500 consecutive cases after Descemet membrane endothelial keratoplasty (DMEK), we ex

43 lial downgrowth is a rare complication after Descemet stripping automated endothelial keratoplasty (D

44 cal course of graft rejection episodes after Descemet membrane endothelial keratoplasty (DMEK).

45 igher-order aberrations (HOAs) in eyes after Descemet's membrane endothelial keratoplasty (DMEK), Des

46 interest associated with graft failure after Descemet stripping automated endothelial keratoplasty (D

47 fications of intraocular lenses (IOLs) after Descemet membrane endothelial keratoplasty (DMEK).

48 Endothelial migration after Descemet's stripping alone in the left eye, with probabl

49 Endothelial cell migration after Descemet's stripping procedure without insertion of endo

50 el) or placebo once daily for 9 months after Descemet membrane endothelial keratoplasty, and 71 fello

51 orneoscleral buttons (n = 10) obtained after Descemet's membrane endothelial keratoplasty.

52 may assist optimizing visual outcomes after Descemet stripping automated endothelial keratoplasty (D

53 This study compared the outcomes after Descemet's membrane endothelial keratoplasty (DMEK) in p

54 lamellar keratoplasty (DALK) performed after Descemet stripping automated endothelial keratoplasty (D

55 Prolonged supine positioning after Descemet membrane endothelial keratoplasty for Fuchs' dy

56 much less frequent than those reported after Descemet's membrane endothelial keratoplasty.

57 the extent of corneal edema resolution after Descemet membrane endothelial keratoplasty (DMEK) may he

58 backscatter with visual acuity results after Descemet membrane endothelial keratoplasty (DMEK) in eye

59 othelial rejection line is rarely seen after Descemet stripping automated endothelial keratoplasties

60 lial cell (EC) loss and graft survival after Descemet's stripping automated endothelial keratoplasty

61 Although ECL 3 years after Descemet stripping automated endothelial keratoplasty is

62 All Descemet membrane endothelial keratoplasty surgical proc

63 Loosening of sutures occurred in 20%, and Descemet detachment in 16%.

64 1992-2013), ALK (date range, 2002-2013), and Descemet's stripping automated EK (date range, 2006-2013

65 ft infiltrate (3), graft dehiscence (3), and Descemet membrane detachment (2).

66 amber, and correlation between donor age and Descemet rolling behavior.

67 ing anterior lamellar keratoplasty (ALK) and Descemet's stripping endothelial keratoplasty (DSEK).

68 n) implantation within the capsular bag, and Descemet stripping automated endothelial keratoplasty us

69 amellar keratoplasty (ALK) in 165 cases, and Descemet stripping with endothelial keratoplasty in 64 c

70 Human corneal endothelial cells and Descemet's membrane (HCEC-DM) complex was dissected from

71 malfunctioning corneal endothelial cells and Descemet's membrane.

72 membrane endothelial keratoplasty (DMEK) and Descemet stripping automated endothelial keratoplasty (D

73 tripping endothelial keratoplasty (DSEK) and Descemet membrane endothelial keratoplasty (DMEK).

74 rneal epithelial basement membrane (EBM) and Descemet's membrane (DM) components exhibit heterogeneou

75 ody punctate staining in the endothelium and Descemet membrane; punctate staining was absent from bot

76 Analysis of the endothelium and Descemet's membrane (DM) was performed using transmissio

77 MEK consists merely of donor endothelium and Descemet's membrane, so DMEK does not create a stromal i

78 The epithelium and Descemet's membrane appeared normal.

79 ial keratoplasty (DSEK) in the right eye and Descemet's stripping only in the left eye.

80 penetrating keratoplasty (PK) in 22 eyes and Descemet's stripping endothelial keratoplasty (DSEK) in

81 pping automated endothelial keratoplasty and Descemet's membrane endothelial keratoplasty in their ma

82 ng (automated) endothelial keratoplasty, and Descemet membrane endothelial keratoplasty with intraocu

83 riate number of fibroblastic cell layers and Descemet's membrane of appropriate thickness.

84 led a corneal ulcer with feathery margin and Descemet's membrane folding.

85 pithelium, epithelial basement membrane, and Descemet membrane.

86 foration of the posterior corneal stroma and Descemet membrane (DM).

87 scopy of the junction between the stroma and Descemet's membrane were performed.

88 in FECD eyes undergoing cataract surgery and Descemet membrane endothelial keratoplasty (DMEK).

89 d by chronic corneal insult after trauma and Descemet stripping automated endothelial keratoplasty (D

90 Corneas were trephined, and Descemet's membrane with HCECs was stripped from the cen

91 nel have become comfortable and competent at Descemet's stripping automated endothelial keratoplasty

92 t 1 month, 12 of 13 patients had an attached Descemet membrane and improved mean logMAR BCVA (P = .00

93 e locations that may displace the attenuated Descemet membrane when located anterior to or at Schwalb

94 A bare Descemet membrane was achieved in all cases.

95 The number of collagen lamellae between Descemet's membrane and most posterior keratocytes varie

96 e eye banks providing precut tissue for both Descemet stripping automated endothelial keratoplasty an

97 r treatment for endothelial dysfunction, but Descemet's membrane endothelial keratoplasty (DMEK) now

98 ndergoing cataract surgery alone followed by Descemet stripping endothelial keratoplasty (DSEK) or co

99 ating keratoplasty (PKP, 50.3%), followed by Descemet's stripping endothelial keratoplasty (DSAEK, 29

100 corneal stroma, lined in some instances, by Descemet membrane.

101 tures (trabecular meshwork, Schlemm's canal, Descemet's membrane), better postural comfort for the su

102 Human corneal endothelial cell-Descemet's membrane (HCEC-DM) complexes from normal and

103 hyperopic refractive outcome after combined Descemet membrane endothelial keratoplasty and cataract

104 While the literature on complex Descemet's membrane endothelial keratoplasty is limited,

105 surgery alone (45 eyes) or with concomitant Descemet membrane endothelial keratoplasty (triple proce

106 ysis, the surgical videos of 100 consecutive Descemet membrane endothelial keratoplasty cases with at

107 Human corneal Descemet's membrane and corneal endothelial cells were d

108 showed the achieved big-bubble and detached Descemet membrane.

109 tionally, it revealed an associated detached Descemet membrane, a feature which has not been previous

110 rientation of an upside-down implanted DMEK (Descemet Membrane Endothelial Keratoplasty) graft 4 week

111 et membrane endothelial keratoplasty (DMEK), Descemet stripping automated endothelial keratoplasty (D

112 's membrane endothelial keratoplasty (DMEK), Descemet's stripping automated endothelial keratoplasty

113 traoperative interface fluid dynamics during Descemet stripping automated endothelial keratoplasty (D

114 l surfaces in patients that underwent either Descemet-stripping-automated-endothelial-keratoplasty (D

115 To evaluate the utility of endothelial/Descemet membrane complex (En/DM) characteristics in dia

116 introduce and position the donor endothelium-Descemet membrane graft tissue.

117 btained by leaving the recipient endothelium-Descemet complex could be the key factor for the success

118 e without removing the recipient endothelium-Descemet complex.

119 ncluded graft rejection, central Endothelium/Descemet's complex thickness, and central corneal thickn

120 etermine whether measurements of Endothelium/Descemet complex thickness (En/DMT) are of predictive va

121 basement membranes in wild-type eyes, except Descemet's membrane, showed immunogold labeling with ant

122 ss anterior stromal corneal scars (15 eyes), Descemet membrane ruptures (6 eyes), and conjunctival or

123 2 cases of failed DMEK, and 1 case of failed Descemet stripping automated endothelial keratoplasty.

124 rring that may limit visual acuity following Descemet stripping endothelial keratoplasty (DSEK).

125 ear course of corneal densitometry following Descemet membrane endothelial keratoplasty (DMEK) for Fu

126 Remnant interface fluid following Descemet stripping automated endothelial keratoplasty (D

127 trating that endothelial cell loss following Descemet stripping automated endothelial keratoplasty (D

128 oplasty, along with the current evidence for Descemet's stripping automated endothelial keratoplasty

129 keratoplasty, may alter the indications for Descemet's stripping automated endothelial keratoplasty,

130 The Supine Positioning for Descemet Membrane Endothelial Keratoplasty Attachment (S

131 SAEK are comparable with those published for Descemet's membrane endothelial keratoplasty and better

132 from donors >=80 years old are suitable for Descemet membrane endothelial keratoplasty (DMEK).

133 bility of preloading endothelial tissues for Descemet membrane endothelial keratoplasty (DMEK).

134 as a personalized descemetorrhexis zone for Descemet stripping only and/or Descemet membrane transpl

135 best studied and the most widely used form; Descemet's stripping automated endothelial keratoplasty

136 tes were observed at variable distances from Descemet's membrane, increasing from 1.5 to 12 mum (mean

137 sterior polymorphous membrane dystrophy from Descemet's membrane specimens removed from each eye.

138 HCECs were then isolated from Descemet's membrane and cultivated.

139 e time required for the DMEK procedure (from Descemet scoring until final air filling) never exceeded

140 a was easily and reproducibly separated from Descemet's membrane with a combination of intrastromal c

141 Three eyes had Descemet stripping done of the same size as the donor gr

142 ient), the anterior banded layer of the host Descemet membrane (DM) was still in situ across the corn

143 However, Descemet's membrane endothelial keratoplasty may be more

144 Stripped human Descemet membranes were digested with collagenase A, and

145 In Descemet membrane endothelial keratoplasty (DMEK), lamel

146 by marked corneal edema caused by a break in Descemet membrane, allowing aqueous to enter the corneal

147 reconstruction of endothelium and guttae in Descemet's membrane over large tissue volumes.

148 year visual acuity and refraction outcome in Descemet stripping automated endothelial keratoplasty (D

149 ar keratoplasty, donor tissue preparation in Descemet's stripping endothelial keratoplasty, and shape

150 elial keratoplasty surgical cases, including Descemet membrane endothelial keratoplasty (DMEK) and De

151 Intact Descemet's membranes isolated from bovine corneas were m

152 Although the intact Descemet membrane protects against dehiscing traumas aft

153 Conservative management of intraoperative Descemet membrane perforation, where possible, may be sa

154 oconus may reduce the rate of intraoperative Descemet perforation and the conversion to PK in a multi

155 re comparable with respect to intraoperative Descemet membrane perforation, the rate of successful bi

156 in 40 pseudophakic eyes after keratoplasty (Descemet stripping with endothelial keratoplasty [DSEK],

157 of CET, including penetrating keratoplasty, Descemet stripping endothelial keratoplasty, or Descemet

158 al epithelium, epithelial basement membrane, Descemet's membrane, ciliary epithelium, lens capsule, r

159 Flat-mounted Descemet's Stripping Automated Endothelial Keratoplasty

160 In the L450W mutant, Descemet's membrane was several times thicker than norma

161 Two eyes underwent non-Descemet stripping endothelial keratoplasty.

162 es depending upon the presence or absence of Descemet's membrane.

163 antation, including increasing acceptance of Descemet's membrane endothelial keratoplasty, may alter

164 The increasing adoption of Descemet's membrane endothelial keratoplast is changing

165 -stromal scarring with a remaining aspect of Descemet's membrane rupture.

166 To report two cases of Descemet Membrane Endothelial Keratoplasty (DMEK) in pat

167 It is a major component of Descemet's membrane, a thick basement membrane under the

168 ty to alterations of collagen composition of Descemet membrane (DM) in advanced Fuchs endothelial cor

169 nectin and collagen type IV, constituents of Descemet's membrane.

170 ated with the characteristic deformations of Descemet's membrane, termed guttae.

171 ed at high levels along the anterior edge of Descemet's, another abnormal feature also found in late-

172 Histological examination of Descemet membrane (DM) excised at the time of endothelia

173 development of guttae, focal excrescences of Descemet's membrane.

174 e endothelial transplantation in the form of Descemet's stripping endothelial keratoplasty (DSEK) is

175 COL8A2 was observed in the anterior half of Descemet's membrane.

176 rior stroma and the anterior banded layer of Descemet's membrane.

177 This study evaluates the longevity of Descemet membrane endothelial keratoplasty (DMEK) grafts

178 osterior stroma (P<0.0001), opacification of Descemet's membrane (P<0.0001), and corneal guttae (P<0.

179 hed literature on the safety and outcomes of Descemet membrane endothelial keratoplasty (DMEK) for th

180 dy was to evaluate the long-term outcomes of Descemet membrane endothelial keratoplasty (DMEK) in eye

181 ce patterns, graft survival, and outcomes of Descemet membrane endothelial keratoplasty (DMEK) in the

182 ms to assess the indications and outcomes of Descemet membrane endothelial keratoplasty (DMEK) surger

183 Intraoperative perforation of Descemet membrane occurred in 15 of 58 (25.9%) F-DALK ca

184 Intraoperative perforation of Descemet membrane occurred in 45.4% of eyes.

185 plicated by an intraoperative perforation of Descemet membrane; no other intraoperative or postoperat

186 elial failure, leading to the performance of Descemet's Stripping Automated Endothelial Keratoplasty

187 of endothelial guttae, small protrusions of Descemet's membrane that are characteristic of FCD.

188 Spontaneous reattachment of Descemet membrane with a clear cornea was achieved at 3

189 e of keratoplasty changed due to the rise of Descemet Membrane Endothelial Keratoplasty (DMEK).

190 served to crystallize the essential role of Descemet's stripping automated endothelial keratoplasty

191 This technique facilitates the separation of Descemet's membrane from the stroma without affecting en

192 entian violet S-stamp to the stromal side of Descemet membrane.

193 At 1 month, final status of Descemet membrane, final best-corrected visual acuity (B

194 Mean ECC loss after stripping of Descemet membrane was 3.9% (range, 6.5% gain to 14.5% lo

195 Demonstrating that success of Descemet stripping automated endothelial keratoplasty is

196 pigmented cells on the posterior surface of Descemet's membrane, pointing to a possible iris injury.

197 in DMEK can equal and even surpass those of Descemet stripping automated endothelial cell keratoplas

198 lial keratoplasty is limited, the utility of Descemet's stripping automated endothelial keratoplasty

199 the posterior stroma and interfacial zone of Descemet's membrane (DM) in canine eyes.

200 age 5 demonstrates hydrops; 5a, acute onset: Descemet's membrane rupture and dilaceration of collagen

201 exis zone for Descemet stripping only and/or Descemet membrane transplantation.

202 neal grafts post penetrating keratoplasty or Descemet stripping automated endothelial keratoplasty: 4

203 cemet stripping endothelial keratoplasty, or Descemet membrane endothelial keratoplasty procedures.

204 proposed that trophozoites cannot penetrate Descemet's membrane and the corneal endothelium to enter

205 The amoebae penetrated Descemet's membrane within 24 hours of in vitro culture.

206 hat A. castellanii is capable of penetrating Descemet's membrane and entering the AC.

207 dle into the deep stroma without penetrating Descemet's membrane.

208 s post-penetrating keratoplasty, 4 eyes post-Descemet stripping automated endothelial keratoplasty, 3

209 e also greatly increased in the of posterior Descemet's membrane, yet another general feature shared

210 the current study revealed that in the pre- Descemet's membrane stroma of the periphery, the degener

211 the existence of a distinctive acellular pre-Descemet's stromal layer in the human cornea.

212 such as acute hydrops, Descematocele and pre-Descemet's dystrophies.

213 recent discovery and characterization of pre-Descemet's layer (PDL; also termed the Dua's layer or th

214 milies with punctiform and polychromatic pre-Descemet corneal dystrophy (PPPCD).

215 ntinuous layer of keratocytes separating pre-Descemet membrane (DM) stroma, DM, and endothelium from

216 -defined, acellular, strong layer in the pre-Descemet's cornea.

217 s corneal graft taken either from a previous Descemet stripping endothelial keratoplasty procedure or

218 ld predict final visual acuity after primary Descemet membrane endothelial keratoplasty (DMEK) has no

219 icient technique for the preparation of pure Descemet membrane grafts.

220 (range, 2%-16%), and the complication rate (Descemet's folds, epitheliopathy, loose sutures) was 18%

221 ry (33.3%), corneal decompensation requiring Descemet's Membrane Endothelial Keratoplasty (20%), and

222 PURPOSE OF REVIEW: Descemet's stripping endothelial keratoplasty (DSEK) has

223 mbers (AC) resulting from non-rhegmatogenous Descemet membrane detachment (DMD) after deep anterior l

224 uded stroma between the graft and the host's Descemet membrane, and approximately 6 mm in group B (23

225 overlapping between the graft and the host's Descemet membrane.

226 he efficacy and safety outcomes of secondary Descemet stripping endothelial keratoplasty (DSEK) and D

227 rate in a cohort with undersized sequential Descemet Membrane Endothelial Keratoplasty (DMEK) due to

228 patient with acute edema due to spontaneous Descemet s (basement) membrane rupture in keratoconus, m

229 or toxic injury of the endothelium, stripped Descemet's membrane, epithelial toxicity and disruption,

230 or toxic injury of the endothelium, stripped Descemet's membrane, epithelial toxicity and disruption,

231 lagenase A, but not Dispase, of the stripped Descemet's membrane generated HCEC aggregates, which pre

232 t in a reproducible separation of the stroma-Descemet's junction.

233 peat descemetopexy for post-cataract surgery Descemet membrane detachment gives good anatomic and vis

234 d initial procedure in post-cataract surgery Descemet membrane detachment.

235 Recent literature demonstrates that Descemet's membrane endothelial keratoplasty provides be

236 The Descemet endothelium complex (DEC) was retrieved during

237 The Descemet graft unfolding methods were categorized into 4

238 The Descemet membrane was thickened to a variable extent in

239 ng zone of interwoven collagen fibers at the Descemet-stroma interface, the findings did not provide

240 llagen types III and VI, was observed at the Descemet-stroma interface.

241 nique using a 27 gauge cannula to detach the Descemet membrane (DM).

242 CE cells scraped from the Descemet's membrane were counted.

243 roscopy and corneal Scheimpflug imaging, the Descemet endothelium complex (DEC) was retrieved during

244 pressure into the posterior stroma or in the Descemet membrane-stroma interface to create the bubble.

245 oid regime, and avoiding decentration of the Descemet graft.

246 ratoplasty (DMEK), lamellar splitting of the Descemet membrane (DM) may occur during stripping of hos

247 The OCT helped to assess the location of the Descemet membrane and guided the manual dissection.

248 d healthy endothelium suggests a role of the Descemet membrane in CHED.

249 nce of guttae, which are excrescences of the Descemet membrane.

250 patients had successful reattachment of the Descemet's membrane (DM) after the intervention.

251 1) creation of BB followed by peeling of the Descemet's membrane (DM); (2) peeling off of the DM foll

252 However, limitations of the Descemet's membrane endothelial keratoplasty procedure h

253 Stripping of the Descemet's membrane was performed under air and the graf

254 e IV collagen on the endothelial face of the Descemet's membrane; and abnormal deposition of stromal

255 A new technique to unfold the Descemet membrane grafts using a single cannula was desc

256 sing controlled techniques for unfolding the Descemet graft inside the recipient anterior chamber, ei

257 ing behind a small area of opacity where the Descemet's tear had healed.

258 Therefore, Descemet's stripping without endothelial replacement was

259 al stroma as well as immediately adjacent to Descemet's membrane.

260 decreased immunologic rejection compared to Descemet's stripping automated endothelial keratoplasty.

261 idually variable distances of keratocytes to Descemet's membrane.

262 rane was absent, whereas its localization to Descemet's membrane was unchanged.

263 tes at the lower portions of guttae, next to Descemet's membrane, whereas CLU localized mostly on top

264 As surgeons transit to Descemet's membrane endothelial keratoplasty (DMEK), eye

265 OCT) may facilitate successful transition to Descemet membrane endothelial keratoplasty (DMEK) surger

266 aoperative macroperforation of the trabeculo-Descemet membrane (5.3%), hyphema (21.1%) and bleb forma

267 To accurately measure ultrathin Descemet stripping automated endothelial keratoplasty (D

268 eal dystrophy (FECD) underwent uncomplicated Descemet membrane endothelial keratoplasty (DMEK), and 5

269 The 3-year success rate in eyes undergoing Descemet stripping automated endothelial keratoplasty wa

270 rebubbling rates between patients undergoing Descemet membrane endothelial keratoplasty (DMEK) with e

271 A total of 34 eyes (34 subjects) undergoing Descemet membrane endothelial keratoplasty (DMEK) surger

272 , but there is no staining in the underlying Descemet's membrane.

273 corneal patch graft, and 2 (1.9%) underwent Descemet stripping automated endothelial keratoplasty (D

274 edema from endothelial dysfunction underwent Descemet's stripping endothelial keratoplasty (DSEK) in

275 1090 individuals (1330 study eyes) underwent Descemet stripping automated endothelial keratoplasty (1

276 One hundred seventeen patients who underwent Descemet membrane endothelial keratoplasty (DMEK).

277 patients with Fuchs' dystrophy who underwent Descemet stripping automated endothelial keratoplasty (D

278 ar surgeries, such as pars plana vitrectomy, Descemet stripping (automated) endothelial keratoplasty,

279 mmon anterior segment surgical procedure was Descemet stripping automated endothelial keratoplasty (D

280 Surgical methods compared were Descemet membrane endothelial keratoplasty (DMEK), Desce

281 e error after cataract surgery combined with Descemet stripping automated endothelial keratoplasty.

282 intraocular lens (IOL) who was treated with Descemet stripping endothelial keratoplasty (DSAEK).

283 However, unlike with Descemet's membrane endothelial keratoplasty, preparatio

284 nd abnormal assembly of collagen VIII within Descemet's membrane, a process that is presumed to begin

285 EK without Descemet stripping has proved to be a successful procedu

286 In November 2010 we performed EK without Descemet Stripping in a 3-month female newborn, thinking

287 In recent years, Descemet membrane endothelial keratoplasty (DMEK) has ga