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1 o cell speeds, and seen in Mouse T cells and Dictyostelium.
2 tes the RasC-mediated activation of TORC2 in Dictyostelium.
3 d is involved in developmental cell death in Dictyostelium.
4 tion leading to multicellular development in Dictyostelium.
5 n-based motility in cell-free systems and in Dictyostelium.
6 sis of the subunits' individual functions in Dictyostelium.
7 nant dynein fragments from budding yeast and Dictyostelium.
8 itical component for chemotaxis signaling in Dictyostelium.
9 ule during starvation-induced development of Dictyostelium.
10 16) identified in cells of the social amoeba Dictyostelium a G protein-coupled receptor (GPCR) that r
13 protein, mediating inhibition of a conserved Dictyostelium AAA ATPase, p97, a homolog of the human tr
16 ue, unbiased phenotypic chemotaxis-dependent Dictyostelium aggregation assay for high-throughput scre
17 e examine cell shape and movement in starved Dictyostelium amoebae during migration toward a chemoatt
20 actor-1 (DIF-1) is a polyketide that induces Dictyostelium amoebae to differentiate as prestalk cells
25 ionship is conserved in the simple eukaryote Dictyostelium and exploit this organism to define mechan
26 e (AMPK) has been proposed to play a role in Dictyostelium and human cytopathology in mitochondrial d
27 ies of both compounds were confirmed in both Dictyostelium and in human neutrophils in a directed EZ-
28 e observed for different chemoattractants in Dictyostelium and in human neutrophils, suggesting an ev
30 AVE activation stops phosphorylation in both Dictyostelium and mammalian cells, implying that phospho
32 yosin II localizes to the cleavage furrow in Dictyostelium and metazoan cells remains largely unknown
33 ression during development of wild-type (WT) Dictyostelium and mutant cells lacking ChdC, a Type III
35 ediates O(2) regulation of the social amoeba Dictyostelium and the parasite Toxoplasma gondii The ful
36 rved F&H interactor was identified, GxcU (in Dictyostelium) and the Cdc42-GEF FGD1-related F-actin bi
37 as orthologue-specific degradation system in Dictyostelium, and further identification of the respons
38 show here that the inositol phospholipids of Dictyostelium are different, being highly enriched in an
40 resistance in HR-deficient cells and present Dictyostelium as a convenient genetic model to character
44 by prioritizing bacterial response genes in Dictyostelium as a novel model system for prokaryote-euk
49 utionize the field of functional genomics in Dictyostelium by greatly expanding the mutation spectrum
51 tory subunit B56, encoded by psrA, modulates Dictyostelium cell differentiation through negatively af
53 1evels of activated Rac in coronin-deficient Dictyostelium cells (corA(-)), which impacts myosin II a
60 criptomics, we identified a subpopulation of Dictyostelium cells experiencing spontaneous DNA damage.
65 ence that the actin machinery of chemotactic Dictyostelium cells operates close to an oscillatory ins
74 ee-dimensional forces exerted by chemotaxing Dictyostelium cells, and examined wild-type cells as wel
75 stem in which human PTEN-GFP is expressed in Dictyostelium cells, we identified mutations in the memb
76 s proliferation and causes chemorepulsion of Dictyostelium cells, yet AprA has little sequence simila
84 ic pathways for chemotaxis and phagocytosis; Dictyostelium chemotax toward bacteria and phagocytose t
89 ation is important for oxygen-sensing during Dictyostelium development and is mediated by a HIF-alpha
90 xylation of Skp1 contributes to O2-dependent Dictyostelium development, but full glycosylation at tha
92 and AcgA, both essential for sporulation in Dictyostelium, did not affect Polysphondylium sporulatio
93 that transcript variability emerging during Dictyostelium differentiation is driven predominantly by
96 lysine-265 (K265) of the myosin-2 motor from Dictyostelium discoideum (Dd) is proposed to be a key re
102 DIRS-1 is the most abundant retroelement in Dictyostelium discoideum and constitutes the pericentrom
103 seudopod-dominated migration of the amoeboid Dictyostelium discoideum and for the lamellipod-driven m
107 intracellular transport are investigated in Dictyostelium discoideum cells by single particle tracki
108 antify the directional biases in chemotactic Dictyostelium discoideum cells in a flow chamber with al
110 y establishment varies across cell types: in Dictyostelium discoideum cells, it is mediated by bioche
111 e early stages of cytokinesis, in rounded-up Dictyostelium discoideum cells, the small G-protein Rap1
115 d material transport within the cytoplasm of Dictyostelium discoideum cells: the anomalous non-linear
119 d for cell surface cAMP receptors throughout Dictyostelium discoideum development, controlling chemot
122 roscopy we directly observe the structure of Dictyostelium discoideum dynein dimers on microtubules a
126 melanogaster, Schizosaccharomyces pombe and Dictyostelium discoideum for methylation of the Geobacte
130 Using bioinformatics tools, we show that Dictyostelium discoideum has the highest content of prio
133 ion-induced aggregation of the social amoeba Dictyostelium discoideum into a multicellular slug is kn
137 es were explored for cellular ion imaging in Dictyostelium discoideum live cells but spontaneous dye
138 min G (ForG) from the professional phagocyte Dictyostelium discoideum localizes to endocytic cups.
141 m species, and the mycetozoan model organism Dictyostelium discoideum Our results show that phenamacr
142 ulticellular slug stage of the social amoeba Dictyostelium discoideum produce ETs upon stimulation wi
143 ew research indicates that the social amoeba Dictyostelium discoideum recognizes distinctions between
144 ides and the unicellular phagocytic organism Dictyostelium discoideum reveal that, like OCRL, the Dic
149 ost is a "farmer" clone of the social amoeba Dictyostelium discoideum that carries and disperses bact
150 ady present in mycetozoan eukaryotes such as Dictyostelium discoideum This social amoeba kills bacter
151 emical mutagenesis in the social soil amoeba Dictyostelium discoideum Through genome sequencing, we s
152 sed this CRISPR-E test in the model organism Dictyostelium discoideum to demonstrate that Dync1li1 is
153 show that PIP(3) is not only unnecessary for Dictyostelium discoideum to migrate toward folate, but a
154 transduction pathways, such as those used by Dictyostelium discoideum to move toward cAMP, use a G pr
156 nserved in the more primitive model organism Dictyostelium discoideum using a microfluidic chip desig
158 mediated signaling network for chemotaxis in Dictyostelium discoideum We identified a negative regula
159 o used for communication in the social ameba Dictyostelium discoideum when the solitary cells aggrega
163 n phytate-loaded Acanthamoeba castellanii or Dictyostelium discoideum, and the intracellular growth d
164 PHD homologues from the cellular slime mold, Dictyostelium discoideum, and the protozoan parasite, To
167 ular slime molds, including the well-studied Dictyostelium discoideum, are amoebae whose life cycle i
168 from Schizosaccharomyces pombe and DnmA from Dictyostelium discoideum, are strongly stimulated by pri
169 n model organisms: Saccharomyces cerevisiae, Dictyostelium discoideum, Caenorhabditis elegans, Drosop
170 In many systems, including the social amoeba Dictyostelium discoideum, development is often marked by
171 some eukaryotes, including the social amoeba Dictyostelium discoideum, encode both a class I and a cl
173 T ortholog in the model developmental system Dictyostelium discoideum, in which Ca(2+) plays a role i
175 is three-step modification pathway exists in Dictyostelium discoideum, model of the evolutionary supe
177 ins from Homo sapiens, Arabidopsis thaliana, Dictyostelium discoideum, Saccharomyces cerevisiae, Esch
180 d in cheating behaviors in the social amoeba Dictyostelium discoideum, testing whether these genes ex
181 ate spore encapsulation in the social amoeba Dictyostelium discoideum, the metabolic profile and othe
185 ine repeats from the single-celled eukaryote Dictyostelium discoideum, which also has a multicellular
186 We test this evolutionary hypothesis in Dictyostelium discoideum, which forms multicellular frui
206 ress currently stores the data from over 800 Dictyostelium experiments and is embedded within a gener
207 ymes thus appear to mediate the synthesis of Dictyostelium extracellular polyphosphate, which is used
208 ostelids, including Dictyostelium purpureum, Dictyostelium fasciculatum and Polysphondylium pallidum.
211 ates the addition of the final two sugars in Dictyostelium, generating Galalpha1, 3Galalpha1,3Fucalph
213 ocytosis of bacteria induced upregulation of Dictyostelium genes encoding the copper uptake transport
215 in Dictyostelium, whereas human H-Ras and a Dictyostelium H-Ras homologue (RasC) are refractory to u
216 gnaling during large-scale endocytosis in WT Dictyostelium has been, for the most part, attributed to
219 nability of c-di-GMP to induce cell death in Dictyostelium HMX44A cells and DH1 cells upon pharmacolo
220 ional myosin 7 (DdMyo7) in the social amoeba Dictyostelium However, the exact roles of these MyTH4-FE
221 e quiescence of organisms such as yeasts and Dictyostelium in response to nutritional starvation and
222 raid as a synthetic biological framework for Dictyostelium, including a library of 250 DNA parts and
224 hydroxyproline by a pentasaccharide that, in Dictyostelium, influences Skp1 structure to favor assemb
226 y distinguish IqgC from other members of the Dictyostelium IQGAP family and call for repositioning of
227 d complementation assays in live cells, that Dictyostelium IQGAP-related protein IqgC interacts with
228 stinct but structurally compatible glycan in Dictyostelium is a remarkable case of convergent evoluti
229 expulsion by the contractile vacuole (CV) in Dictyostelium is carried out by a giant kiss-and-run foc
231 nism for interaction with the environment in Dictyostelium is unknown and thus, we explore different
232 mediated cytofission, originally observed in Dictyostelium, is relevant to human biology--where it se
237 ACA produces the cAMP pulses that coordinate Dictyostelium morphogenetic cell movement and is highly
238 trate active nucleosome repositioning during Dictyostelium multicellular development, establish an in
242 Now we show that PH domains occur in all Dictyostelium myosin 1s and that the BH sites of Myo1A,
245 muscle myosin, beta-cardiac myosin (CMIIB), Dictyostelium myosin II (DdMII), and nonmuscle myosin II
247 ns to resolve a structural transition in the Dictyostelium myosin II relay helix during the actin-act
248 spin label (BSL) bound stereospecifically to Dictyostelium myosin II, we determined with high resolut
251 tic properties of the alpha-kinase domain of Dictyostelium myosin-II heavy chain kinase-A (termed A-C
253 elium discoideum reveal that, like OCRL, the Dictyostelium OCRL orthologue Dd5P4 binds two proteins c
254 ed that c-di-GMP could trigger cell death in Dictyostelium only in the presence of the DIF-1 polyketi
256 s been, for the most part, attributed to the Dictyostelium ortholog of human RasGAP NF1, in commonly
262 Pathological mutations were recreated in the Dictyostelium protein and expressed in the mutant backgr
263 gh basal and poststimulus phosphorylation of Dictyostelium protein kinase B (PKB) kinase family membe
267 up to host multiple Dictyostelids, including Dictyostelium purpureum, Dictyostelium fasciculatum and
268 es of CP knockdown, overexpression of V-1 in Dictyostelium reduced the size of pseudopodia and the co
272 te that the C-terminal acidic domain of most Dictyostelium SCAR is basally phosphorylated at four ser
284 Here, we exploit the genetic versatility of Dictyostelium to investigate the effects of physiologica
286 egulates multiple physiological processes as Dictyostelium transitions from a group of unicellular am
287 myosin 10 (Myo10) in mammalian cells and of Dictyostelium unconventional myosin 7 (DdMyo7) in the so
292 r modification is found in the social amoeba Dictyostelium, where it regulates SCF assembly and O2-de
293 ergoes polyubiquitin-mediated degradation in Dictyostelium, whereas human H-Ras and a Dictyostelium H
294 monstrate conservation of these phenomena in Dictyostelium which has three single-copy H3 variant gen
295 ogical significance of this CP antagonist in Dictyostelium, which expresses a V-1 homolog that we sho
297 l resistance induces bleb-driven movement in Dictyostelium, which is chemotactic and controlled throu
300 developmental self-organisation is shown by Dictyostelium, with cells segregating into two major fat