ライフサイエンスコーパス: ECP

1 and inflammatory features (IL-12, IL-13 and ECP).

2 NACs to measure eosinophil cationic protein (ECP).

3 ) treated with extracorporeal photopheresis (ECP).

4 toxin (EDN) and eosinophil cationic protein (ECP).

5 be induced by extracorporeal photopheresis (ECP).

6 rse VBLL as a percentage of pre-course VBLL (ECP).

7 oxicity was greater in patients treated with ECP.

8 ight into the biogenesis and architecture of ECP.

9 line from the rate of decline 6 months after ECP.

10 tivity), EPP showed higher value rather than ECP.

11 ECP, and 8 of 10 had a clinical response to ECP.

12 lls in all patients before the initiation of ECP.

13 ents were observed for EPP in comparing with ECP.

14 te specificity and low catalytic activity of ECP.

15 times (P = 0.008) more likely to respond to ECP.

16 produced the novel anti-pathogen function of ECP.

17 ip between FEV1 versus time before and after ECP.

18 hanges in CD4+ % at 6, 9, and 12 months post-ECP.

19 at either 6 or 16 months after initiation of ECP.

20 ng the mechanism leading to a response after ECP.

21 sponders at 56 weeks who were 12 months post-ECP.

22 aGVHD achieved complete remission (CR) after ECP.

23 induction of immunostimulatory mediators by ECP.

24 sight into the immunostimulatory capacity of ECP.

25 ethylated crystalline pectin in both EPP and ECP.

26 aqueous shunt to extraocular reservoir, and ECP.

27 The forward primer is attached to the ECP.

28 centrates and peripheral blood samples after ECP.

29 the relative associations of covariates with ECP.

30 Low haemoglobin was associated with higher ECP.

31 ons that were similar to those effective for eCPS.

32 and functional ortholog of primate EDNs and ECPs.

33 Alignments of ECP-1 and ECP-2 demonstrate highly conserved N termini,

34 in the core fiber, our findings suggest that ECP-1 and ECP-2 play important structural roles in the e

35 ith the distinctive protein architectures of ECP-1 and ECP-2, along with their co-localization with T

36 ECP-1 monomeric units were also shown to assemble into h

37 tein data base using the primary sequence of ECP-1 revealed similarity to fibroins from spiders and s

38 tricted patterns of expression for fibroins, ECP-1 was demonstrated to be predominantly produced in t

39 tely 52% identity to the egg case protein 1 (ECP-1) fibroin-like family member.

40 e, containing tubuliform spidroin 1 (TuSp1), ECP-1, and ECP-2.

41 Relative to ECP-1, ECP-2 mRNA levels were determined to be >2-fold h

42 netics, we have isolated a novel gene called ecp-1, which encodes for one of the protein components o

43 ch mapped to two distinct regions within the ECP-1.

44 be identified within the primary sequence of ECP-1.

45 n yield (29.17%) than eggplant calyx pectin (ECP; 18.36%).

46 poor communication from eye care providers (ECPs), (2) patients' lack of finances/insurance coverage

47 Alignments of ECP-1 and ECP-2 demonstrate highly conserved N termini, with 16 Cy

48 iption quantitative PCR analysis showed that ECP-2 is predominantly expressed in the tubuliform gland

49 Relative to ECP-1, ECP-2 mRNA levels were determined to be >2-fold higher.

50 e fiber, our findings suggest that ECP-1 and ECP-2 play important structural roles in the egg case si

51 e have named this factor egg case protein 2 (ECP-2).

52 stinctive protein architectures of ECP-1 and ECP-2, along with their co-localization with TuSp1 in th

53 oorly represented in the primary sequence of ECP-2, but scattered blocks of polyalanine were present,

54 ng tubuliform spidroin 1 (TuSp1), ECP-1, and ECP-2.

55 At the time of ECP, 22 (49%) and 23 (51%) of 45 patients with aGHVD wer

56 resulted in complete loss of GAT function in eCPS (3).

57 receiving better communication/feedback from ECPs, (3) having ophthalmologists hold clinic days in pr

58 6 evaluable patients in early chronic phase (ECP), a major cytogenetic response with interferon-based

59 Extracorporeal photopheresis (ECP), a technique that exposes isolated white blood cell

60 lution, the crystal structure of uncomplexed ECP-actin contains actin in a typical closed conformatio

61 st to the much more open conformation of the ECP-actin's nucleotide binding cleft in solution, the cr

62 of the true uncomplexed ECP32-cleaved actin (ECP-actin) solved to 1.9 A resolution is reported.

63 e activity and that agr cross talk modulates Ecp activity in a manner that mirrors the agr reporter r

64 ECP after 19-d courses (n = 2,262) was lower in older ch

65 The ECP agreed that training in nontechnical skill assessmen

66 ossmatch tests performed using donor-derived ECPs allow for the identification of alloantibodies that

67 d empirical fitting of the values for Cp(3)M-ECp allowed the prediction of binding energy estimates f

68 Our results suggest that ECP alters alloreactivity by affecting allo-targeted eff

69 estigated the distribution and production of ECP among a collection of 136 human CF-positive and CF-n

70 Extracorporeal photopheresis (ECP), an immunomodulating procedure that treats pheresed

71 We found that ECP and BFP structures can be simultaneously observed in

72 s with the hypereosinophilic syndrome showed ECP and EDN deposition comparable to that in guinea pig

73 In conclusion, ECP and EDN disrupt skin integrity and cause inflammatio

74 ECP and EDN each induced distinct skin lesions at >or=2.

75 ECP and EDN localized to dermal cells within 2 days, whe

76 cellular localization and RNase activity of ECP and EDN were critical for lesion formation; differen

77 of other eosinophil granule proteins (e.g., ECP and EDN), which often detect the presence of these p

78 nd thus of the two eosinophil ribonucleases, ECP and eosinophil-derived neurotoxin (EDN)] remains con

79 MATERIALS AND We analyzed ECP and histamine production in response to LPS by ELISA

80 FeNO, ECP and IL-8 were all low in the paucigranulocytic, wher

81 5%-95%; P < or =.002) after a 2-day cycle of ECP and longitudinally over the 12-month course of thera

82 ence for promotion of IL-1beta production by ECP and offer new insight into the immunostimulatory cap

83 nety-five patients were randomized to either ECP and standard therapy (n = 48) or standard therapy al

84 of additional subtypes of glaucoma, whereas ECP and TCP are generally reserved for refractory glauco

85 ve to spotlight the unique nature of EDN and ECP and the unusual evolutionary constraints to which th

86 No significant change in sputum ECP and tryptase was observed between rPAF-AH and placeb

87 ranule proteins eosinophil cationic protein (ECP) and eosinophil peroxidase (EPO) (P < .05), while IF

88 es and (ii) the eosinophil cationic protein (ECP) and eosinophil-derived neurotoxin (EDN) genes.

89 The genes for eosinophil cationic protein (ECP) and eosinophil-derived neurotoxin (EDN) in primates

90 Eosinophil cationic protein (ECP) and eosinophil-derived neurotoxin (EDN), the eosino

91 For both RNase A(ECP) and H48A there is a 10-fold decrease in the product

92 al response to extracorporeal photopheresis (ECP) and mortality after ECP in lung allograft recipient

93 g donor-derived endothelial cell precursors (ECPs) and kidney allograft rejection and function.

94 ifferentials, eosinophilic cationic protein (ECP), and tryptase were evaluated.

95 to Th2 (IL-4, IL-10) cytokine profile after ECP, and 8 of 10 had a clinical response to ECP.

96 d absolute counts of Treg cells changed post-ECP, and examined correlation with response.

97 scribed here is N-glycosylated, as is native ECP, and has approximately 100-fold more ribonuclease ac

98 g-2, VEGF, TGF-beta1, Cys-LTs, MMP-2, IL-13, ECP, and IL-8 measurement in supernatants.

99 lyzed for immune cell populations, tryptase, ECP, and sIgE.

100 s who had refractory cGVHD were treated with ECP, and the clinical response to and immunologic effect

101 BDNF correlated with disease activity, serum ECP, and total IgE serum levels in AD.

102 cells, and the binding was blocked with anti-ECP antibodies, confirming that the pili possess adhesin

103 was demonstrated with an ecpR-GFP fusion and ECP antibodies.

104 The first criterion requires that the ECPs are in their oxidized state, but the high charge de

105 Electrically conducting polymers (ECPs) are one of the most popular types of materials to

106 eukotrienes and eosinophil cationic protein (ECP), are well-known mediators of inflammation and tissu

107 rovement in TSS at week 12 was 14.5% for the ECP arm and 8.5% for the control arm (P = .48).

108 ecrease from baseline in TSS was 8.3% in the ECP arm at week 12 and 0% in the control arm (P = .04).

109 ned to erlotinib alone (arm A; n = 81) or to ECP (arm B; n = 100).

110 We demonstrate that the use of ECP as a prophylaxis prior to conditioning significantly

111 CRSsNP and CRSwNP, identifying S aureus and ECP as novel and crucial players in this process.

112 High BAFF at 1-month ECP associated with a worsening median 6-month skin scor

113 with blood involvement who were treated with ECP at our institute.

114 In particular, early commencement of ECP at treatment lines 1 to 3 yielded a TTNT of 47 month

115 The majority (88%) of patients commenced ECP at treatment lines 1 to 3, either as a monotherapy o

116 s the best E(0) reproducibility reported for ECP-based SCISEs.

117 doping ion by which the oxidized form of the ECP becomes hydrophobic.

118 factor (BAFF) in 46 cGVHD patients receiving ECP before and during treatment course.

119 The CR rate in patients who started ECP being nonresponsive and in PR after steroid was 86%

120 Purified ECP bound in a dose-dependent manner to epithelial cells

121 ECP bound to oligosaccharides of at least arabinotriose

122 ognition of the BS by the E complex protein (ECP) branchpoint bridging protein (BBP).

123 xpression of the Histidine decarboxylase and ECP by flow cytometry and fluorescence microscopy in neu

124 ubstitution of the corresponding residues in eCPS by their fCPS counterparts (Leu --> Lys and Gln -->

125 immunoassay, eosinophilic cationic protein (ECP) by fluoroimmunoassay, prostanoids (PGE(2), PGD(2),

126 The ECP(C(10)-C(30)) concentrations ranged from 1.5 to 67 mu

127 -chromosome inactivation) in the majority of ECP CML patients, before and after mobilization and irre

128 electrochemically active conducting polymer (ECP) coating the working electrode of an electrochemical

129 factor, herein called E. coli common pilus (ECP), composed of a 21-kDa pilin subunit whose amino aci

130 irway secretions from RSV-infected patients; ECP concentrations correlated with MIP-1-alpha concentra

131 The correlation between MIP-1-alpha and ECP concentrations suggests a role for eosinophil degran

132 Follow-up analysis of Ecp confirmed the RNAIII is required to induce protease

133 e findings strongly suggested an alternative eCPS conformation relative to the single crystal conform

134 dues to share a disulfide bond, indicated an eCPS conformational change at least partly similar to th

135 l mutation analysis of Escherichia coli CPS (eCPS), creating P909C and G919C and establishing the abi

136 findings fed into an Expert Consensus Panel (ECP) Delphi approach to establish consensus regarding tr

137 e of an inflammasome-independent pathway for ECP-dependent IL-1beta maturation.

138 The crystal structure of human ECP, determined at 2.4 A, is similar to that of RNase A

139 Levels of IL-6 and ECP did not change significantly during the study.

140 suggesting that they were also influenced by ECP, especially polysaccharides.

141 eresis (ECP) is thought to contribute to how ECP exerts its therapeutic effect in patients with chron

142 The chimera (RNase A(ECP)) experiences only local perturbations in NMR backbo

143 ECPs facilitate U1 association with RNAs with weak 5' SS

144 also derive a structural model for entwined ECP fibers that not only illuminates interbacteria commu

145 tometry in 32 patients with cGvHD treated by ECP for a minimum of 3 months, and up to 12 months.

146 suggests that early BAFF measurement during ECP for cGVHD represents a potentially useful biomarker

147 lines in the United Kingdom that recommended ECP for patients with advanced CTCL, particularly after

148 ited in 6 Italian centers, were submitted to ECP for second-line treatment.

149 ults of our study support the utilization of ECP for SS/e-MF, and we recommend that ECP should be con

150 nd efficacy of extracorporeal photopheresis (ECP) for 12 to 24 weeks together with standard therapy w

151 use genes identified as orthologs of EDN and ECP form a highly divergent, species-limited cluster.

152 as the human eosinophilic cationic protein (ECP), from intracellular granules is central to the role

153 Better communication between PCPs and ECPs, further implementation of EMRs, and increasing eye

154 ong to the ribonuclease gene family, and the ECP gene, whose product has an anti-pathogen function no

155 rated in the early stage of evolution of the ECP gene.

156 e time of mobilization (early chronic phase [ECP] > late CP > accelerated phase).

157 Extracorporeal photochemotherapy (ECP) has been associated with clinical improvement in se

158 Extracorporeal photochemotherapy (ECP) has been shown to be an effective therapy for patie

159 Extracorporeal photopheresis (ECP) has demonstrated therapeutic benefit in patients wi

160 vestigated, attempts to make saturated black ECPs have not been reported, probably owing to the compl

161 tions (M06-2X/aug-cc-pVDZ/Hay-Wadt VDZ (n+1) ECP), highlighting the remarkable effect of acid on the

162 detection and more timely implementation of ECP (ie, when FEV1 values >1.5 L) should be considered e

163 ing of mitochondrial DNA in association with ECP in a concentration- and time-dependent manner.

164 cant increase of eosinophils, monocytes, and ECP in induced sputum at V3 compared with V1.

165 real photopheresis (ECP) and mortality after ECP in lung allograft recipients with bronchiolitis obli

166 survival was seen among patients who started ECP in PR after steroid (80% vs 50% at 2 years; P = 0.07

167 These data suggest an important role for ECP in the biology of ETEC, particularly in CF-negative

168 To examine the efficacy of ECP in the modern era of novel therapies, we conducted a

169 ECP in the nasal lavage increased after the NAC-P in the

170 ge of neutrophils as source of histamine and ECP in the progression of the periodontitis disease.

171 erence in planta was mediated by the adhesin EcpD in combination with the structural subunit, EcpA, a

172 hil numbers and eosinophil cationic protein (ECP) in both nasal washes and serum, along with total Ig

173 ctoferrin and eosinophilic cationic protein (ECP) in nasal secretions.

174 f P. aeruginosa to silicon was controlled by ECP, in addition to LPS.

175 Immunologic effects observed after ECP included normalization of inverted ratios of CD4 to

176 number of endoscopic cyclophotocoagulations (ECPs) increased 99% from 5383 to 10 728.

177 en randomly showed that 58% of them produced ECP independently of the presence or absence of CFs, a p

178 NBO/NLMO bonding analyses on Cp(3)U-ECp indicate that the bonding consists predominantly of

179 phil counts and eosinophil cationic protein (ECP)] induced by bronchial instillation of house dust mi

180 Principal component analysis of the ECP-induced monocyte transcriptome reveals that activati

181 This study reveals that ECP induces a high percentage of processed monocytes to

182 Because ECP induces normal monocytes to enter the DC differentia

183 relationship between FEV1 versus time before ECP initiation.

184 ify patients who died within 16 months after ECP initiation.

185 ith mortality (P = 0.007) at 16 months after ECP initiation.

186 ECP is a pilus of EHEC O157:H7 with a potential role in

187 ess, evidence for considerable divergence of ECP is also implicit in the structure.

188 Our data indicate that ECP is an accessory factor that, in association with BFP

189 We infer that ECP is effective even in patients with extensive cutaneo

190 predictor of mortality, and the response to ECP is influenced by both the extent (>40 mL/mo) and sta

191 ECP is now under investigation for use in patients with

192 ECP is thought to control these diseases in part through

193 is rarely found in other organisms, whereas ECP is widespread in E. coli and other environmental ent

194 Extracorporeal photopheresis (ECP) is a widely used clinical cell-based therapy exhibi

195 Extracorporeal photopheresis (ECP) is an important therapeutic option in steroid-refra

196 Extracorporeal photopheresis (ECP) is considered a valid second-line treatment for acu

197 Eosinophil cationic protein (ECP) is located in the matrix of the eosinophil's large

198 Eosinophil cationic protein (ECP) is one of two RNase A-superfamily ribonucleases fou

199 The Escherichia coli common pilus (ECP) is produced by commensal and pathogenic E. coli str

200 g) cells after extracorporeal photopheresis (ECP) is thought to contribute to how ECP exerts its ther

201 Extracorporeal photochemotherapy (ECP) is widely used to treat cutaneous T-cell lymphoma,

202 ECP levels were >200 ng/ml in 61% of persons with colds

203 Leukotriene and ECP levels were measured using EIAs or ELISAs.

204 Spinach was found to be enriched for ECP/LM13 targets compared with lettuce.

205 were performed on the model complexes Cp(3)M-ECp (M = Nd, U; E = Al, Ga), and empirical fitting of th

206 the isostructural complexes (CpSiMe(3))(3)M-ECp* (M = U, E = Al (1); M = U, E = Ga (2); M = Nd, E =

207 These results suggest that ECP may have a steroid-sparing effect in the treatment o

208 Appropriately modified by future advances, ECP may potentially offer a general source of therapeuti

209 The use of prophylactic ECP may provide an alternative and safe method for immun

210 the hypothesis that in patients with cGVHD, ECP modulates alloreactivity by affecting activated lymp

211 The results suggest that ECP modulates both NK cells and APC populations in patie

212 sidues are distributed on the surface of the ECP molecule that may have implications for an understan

213 The use of ECP monotherapy resulted in a significantly longer media

214 An ECP mutant showed only a modest reduction in adherence t

215 RAST), nasal eosinophilia, or elevated nasal ECP (odds ratios = 17, 21, and 25, respectively).

216 To further elucidate the effects of ECP on activated lymphocyte subpopulations and the inter

217 sess the effect of Staphylococcus aureus and ECP on sRAGE processing.

218 accharides (LPS) and extracellular polymers (ECP) on the adhesion of Pseudomonas aeruginosa PAO1 (exp

219 ters that may be associated with response to ECP or mortality at either 6 or 16 months after initiati

220 We injected eosinophil cationic protein (ECP or RNase 3), eosinophil-derived neurotoxin (EDN or R

221 These lesions were ulcerated (ECP) or crusted (EDN) with marked cellular infiltration.

222 geted for adherence by E. coli common pilus (ECP; or meningitis-associated and temperature-regulated

223 vealed a significant improvement in favor of ECP (P < .001).

224 e 12 times more likely to have a response to ECP (P = 0.0001).

225 ECP plays a dual role in early-stage biofilm development

226 genic mutant strains tested, suggesting that ECP plays a synergistic role in adherence.

227 BAFF level at 1 month of ECP predicted 3- and 6-month skin disease response, with

228 ECP primes IL-1beta production and activates IL-1beta ma

229 e distinctive molecular signature, common to ECP-processed monocytes from normal subjects, and those

230 Our data suggest that ECP production is a common feature of E. coli colonizing

231 ECP production was demonstrated in 121 (71.6%) of a tota

232 Processable black-to-transmissive ECPs promise to affect the development of both reflectiv

233 In this article, we show that ECP promotes marked release of the prototypic immunostim

234 microarray studies revealed that exoenzymes (Ecp protease and Geh lipase) and low-molecular-weight to

235 ntrations were associated with high IL-5 and ECP protein levels.

236 Escherichia coli CPS (eCPS) provides CP for both arginine and pyrimidine nucle

237 The ECP reached consensus regarding who should be targeted t

238 90 both caused inhibition of eotaxin-induced ECP release and chemotaxis.

239 In addition to cys-LTs, LL-37 enhances ECP release from eosinophils via pERK1/2.

240 ECP release was measured by radioimmunoassay.

241 eotaxin-induced eosinophil cationic protein (ECP) release and chemotaxis.

242 lasmid present in nonadherent E. coli HB101, ECP rendered this organism highly adherent at levels com

243 se A homologue, eosinophil cationic protein (ECP), replaced the 12-residue loop 1 in RNase A.

244 The Escherichia coli common pilus (ECP) represents a remarkable family of extracellular fib

245 most recently green electrochromic polymers (ECPs) required for additive primary colour space were in

246 id refractory cGHVD achieved CR and PR after ECP, respectively.

247 of the product analogue, 3'-CMP, to RNase A(ECP) results in only minor chemical shift changes in the

248 rate that the transfer of cells treated with ECP reverses established GVHD by increasing donor regula

249 emical characterization of recombinant human ECP (rhECP) prepared in baculovirus, and demonstrate tha

250 N, RNase 2) and eosinophil cationic protein (ECP, RNase 3), from >50 human individuals.

251 While RNase 7 and ECP/RNase 3 are both cationic and share this particular

252 pression patterns, suggests that RNase 7 and ECP/RNase 3 may have been recruited to target different

253 Of particular interest, ECP/RNase 3's cationicity is based on an (over)abundance

254 DN/RNase 2) and eosinophil cationic protein (ECP/RNase 3), are among the most rapidly evolving coding

255 cationic RNase, eosinophil cationic protein (ECP/RNase 3, pI 11.4).

256 on of ECP for SS/e-MF, and we recommend that ECP should be considered as early as possible in the tre

257 parameters predicted a favorable response to ECP, so patient selection must continue to be made on cl

258 The efficiency with which ECP stimulates new functional DCs supports the possibili

259 blade and endoscopic cyclophotocoagulation (ECP) surgeries in patients with primary open angle glauc

260 opic and transscleral cyclophotocoagulation (ECP, TCP) are generally reserved for refractory glaucoma

261 This article reviews the evolution of the ECP technique--for example, the most recent generation o

262 higher median Treg cell counts 3 months post-ECP than nonresponders, as did steroid responders at 56

263 higher levels of histidine decarboxylase and ECP than those from healthy volunteers, and they also re

264 s from patients with chronic GVHD undergoing ECP therapy.

265 the recently described E. coli common pilus (ECP) to the overall adherence properties of EPEC.

266 h SCORAD score, eosinophil cationic protein (ECP), total IgE, IL-4, IL-13 and IL-31 in children with

267 ECP-treated autologous splenocytes resulted in immune to

268 e developed a novel method for incorporating ECP treatment into well-established and clinically relev

269 r lysine-aspirin challenge were analyzed for ECP, tryptase, PGE2 , PGD2 , LTD4 , and LTE4 .

270 I 69.7%-79.7%); among 159 inpatient courses, ECP was 47.7% (95% CI 39.7%-57.3%).

271 Overall mean ECP was 74.5% (95% CI 69.7%-79.7%); among 159 inpatient

272 Response to ECP was assigned when a positive integer was derived aft

273 We reported that clinical response to ECP was associated not only with normalization of skewed

274 ed expiratory volume in 1 second just before ECP was associated with mortality (P = 0.007) at 16 mont

275 Of interest, IL-1beta maturation by ECP was fully intact in murine cells deficient in caspas

276 ECP was generally well tolerated.

277 high in HG (homogalacturonan) (58.6%), while ECP was high in RG-I (rhamnogalacturonan-I) (44.9%).

278 pression of ICAM-1 on A549 cells, release of ECP was inhibited significantly by anti-CD18 mAb, but no

279 ECP was initiated approximately 2 years after onset of c

280 among cGvHD patients, and the increase post-ECP was not significant until 6 months.

281 The induction of this tolerant state by ECP was obviated by cotreatment with lipopolysaccharide,

282 the release of sRAGE from the tissue, while ECP was shown to be implicated in the breakdown of free

283 Patients whose decline in FEV1 before ECP was statistically significant (P < 0.05) were nearly

284 on of both AECAs and HLA antibodies bound to ECPs was performed using flow cytometry.

285 ociation with eosinophilic cationic protein (ECP) was detected by fluorescence staining techniques an

286 rk with the glutamine-utilizing E. coli CPS (eCPS), we have targeted residues Lys258 and Glu261 in th

287 Sputum cys-LT and ECP were a mean (95% CI) 1.6-fold (1.1, 2.5) and 6.4-fol

288 or Treg cells at baseline to 12 months post-ECP were compared with changes in skin disease scores or

289 Both of EPP and ECP were high in methoxyl and rich in galacturonic acid.

290 cigranulocytic, whereas as expected FeNO and ECP were higher in eosinophilic and mixed asthma, while

291 (baseline) and 6 months after initiation of ECP were used to plot the linear relationship between FE

292 CPS, in which the C-terminal 136 residues of eCPS were replaced by the corresponding residues of sCPS

293 -8, IL-13 and eosinophilic cationic protein (ECP) were also measured in sputum supernatant.

294 RAGE, IL-5, and eosinophil cationic protein (ECP) were quantitatively assessed in inflamed tissue of

295 , eosinophils released significant amount of ECP when cultured with RSV-infected A549 cells.

296 NSAID-UA subjects showed no changes in nasal ECP, whereas subjects with AERD had increased levels of

297 toxin (EDN) and eosinophil cationic protein (ECP), which have incorporated nonsilent mutations at ver

298 duction and potential stability, the p-doped ECPs with low oxidation potentials such as PPy need to b

299 s subjects with AERD had increased levels of ECP, with the highest peak at 15 min after challenge (P

300 there has been progress in understanding how ECP works at the cellular level.