ライフサイエンスコーパス: EIEC

1 tudy, we analyzed the genome sequences of 20 EIEC isolates, including 14 first described in this stud

2 52%; n = 13), followed by EAEC (20%; n = 5), EIEC (12%; n = 3), EHEC (8%; n = 2) and ETEC 2 (8%; n =

3 hat a form of pINV was present in nearly all EIEC genomes, but the Mxi-Spa-Ipa region of the plasmid

4 Among EIEC strains, two types of colicin Js-sensitive phenotyp

5 reased the detection of Shigella species and EIEC from 58% to 79% among patients with dysentery and f

6 agic E. coli (EHEC), enteroinvasive E. coli (EIEC) and enterotoxigenic E. coli (ETEC) are major cause

7 cing E. coli (STEC), enteroinvasive E. coli (EIEC), and Giardia lamblia.

8 li [STEC]), Shigella/enteroinvasive E. coli (EIEC), protozoa (Cryptosporidium, Giardia lamblia, and E

9 coli: ybbW, Shigella/enteroinvasive E. coli (EIEC): ipaH, Giardia duodenalis: B-giardin) using drople

10 ella spp or enteroinvasive Escherichia coli (EIEC) and Campylobactor jejuni o C coli (around two time

11 la spp. and enteroinvasive Escherichia coli (EIEC) from a variety of geographical locations was scree

12 ng Shigella/enteroinvasive Escherichia coli (EIEC) in about an hour.

13 higella and enteroinvasive Escherichia coli (EIEC) infections.

14 Enteroinvasive Escherichia coli (EIEC) is a unique pathovar that has a pathogenic mechani

15 s-sensitive enteroinvasive Escherichia coli (EIEC) strain O164 was made in colicin Js-resistant strai

16 Enteroinvasive Escherichia coli (EIEC), known for causing bacillary dysentery akin to Shi

17 , Shigella, enteroinvasive Escherichia coli (EIEC), Vibrio, and Yersinia.

18 were unique to each of the three identified EIEC lineages.

19 and can be frequent causes of human illness, EIEC causes far fewer reported illnesses each year.

20 Additionally, LF-EIEC exhibited extensive colonization of the mouse intes

21 In this study, we sought to characterize LF-EIEC clinical isolates and assessed their pathogenic pot

22 Together, our findings highlight LF-EIEC as an emerging pathogenic variant warranting height

23 gella-like virulence factors, the role of LF-EIEC in human disease remains underexplored.

24 ession of virulence encoding genes by the LF-EIEC (p < 0.05) were noted during infection to Int407 ce

25 stly confined to NLF-EIEC but some of the LF-EIEC were resistant only to ceftriaxone.

26 s study support the hypothesis that multiple EIEC lineages have evolved independently from multiple d

27 rrhoeal stool specimens, six LF and nine NLF-EIEC were isolated, predominantly belonging to serogroup

28 tion antibiotics were mostly confined to NLF-EIEC but some of the LF-EIEC were resistant only to ceft

29 ir pathogenic potential in comparison to NLF-EIEC.

30 While NLF-EIEC is a well-established pathogen associated with acut

31 Both the types of EIEC had multiple plasmids harbouring several virulence

32 three distinct lineages that contained only EIEC genomes, compared to reference genomes from each of

33 cts of patients who did not have Shigella or EIEC infections.

34 ods was used to identify Shigella species or EIEC among 154 patients with dysentery, 154 age-matched

35 Shigella/EIEC was identified by the GI panel in the PRE (n = 30)

36 inpatient norovirus, rotavirus, and Shigella/EIEC cases.

37 %), Salmonella species (12.4%), and Shigella/EIEC species (12.4%).

38 (71% annual infection risk) and by Shigella/EIEC was 4000-fold (40% annual infection risk) greater t

39 rus, Campylobacter jejuni, and Shigella spp./EIEC) concentrations were used with QMRA to model infect

40 Unlike other E. coli, all the EIEC isolates were non-motile.

41 Phylogenomic analysis of the EIEC genomes demonstrated that 17 of the isolates are pr

42 ated proteins was absent from several of the EIEC isolates.

43 While many of the EIEC lineage-specific genes have unknown functions, thos