ライフサイエンスコーパス: Forsythia

1 dontalis, Streptococcus spp., and Tannerella forsythia.

2 y to the S-layer glycoproteins of Tannerella forsythia.

3 cell adherence and invasion abilities of T. forsythia.

4 dia, Fusobacterium nucleatum, and Tannerella forsythia.

5 nd P. gingivalis, and after 12 months for T. forsythia.

6 , and levels of P. gingivalis (0.23%) and T. forsythia (0.35%), receiver operating characteristic cur

7 Tannerella forsythia (1.5 x 10(5)) and Veillonella parvula (1.02 x

8 denticola, 1.99 (0.992, 4.00), P = 0.052; T. forsythia, 1.95 (1.0, 3.84), P = 0.05; A. naeslundii, 0.

9 tinomycetemcomitans, (31%; P = 0.025), or T. forsythia (63%; P = 0.030).

10 rboring P. gingivalis (46%; P < 0.001) or T. forsythia (63%; P = 0.043) but not A. actinomycetemcomit

11 dontal treatment were as follows: Tannerella forsythia, 81%; Porphyromonas gingivalis, 78%; and Aggre

12 rphyromonas gingivalis (78%/66%), Tannerella forsythia (98%/84%), Treponema denticola (94%/74%), Parv

13 (miropin) from the human pathogen Tannerella forsythia, a bacterium implicated in initiation and prog

14 ke other bacteria, the pathogenic Tannerella forsythia, a member of the red complex group of bacteria

15 vel metalloproteinase secreted by Tannerella forsythia, a well-recognized pathogen strongly associate

16 ductions of PI, GI, total bacterial load, T. forsythia, A. actinomycetemcomitans, and GCF volume.

17 In this study, we showed that T. forsythia activates murine APCs primarily through TLR2-d

18 mination in Campylobacter rectus, Tannerella forsythia, Aggregatibacter actinomycetemcomitans, and Pe

19 vels of Porphyromonas gingivalis, Tannerella forsythia, Aggregatibacter actinomycetemcomitans, and to

20 In forsythia and alfalfa, pith parenchyma cells next to the

21 enome of the periodontal pathogen Tannerella forsythia and also identify antibiotic resistance genes,

22 ant association between the reductions of T. forsythia and being free from PD >/=5 mm.

23 association between reductions of Tannerella forsythia and being free from PD >/=5 mm.

24 T. forsythia and C. rectus were detected in 100% of the sam

25 rstanding of immune evasion strategies of T. forsythia and expand the knowledge on molecular mechanis

26 cluding Porphyromonas gingivalis, Tannerella forsythia and Filifactor alocis, as potential pathogens

27 rs to be an important virulence factor of T. forsythia and might have several important implications

28 thogens Porphyromonas gingivalis, Tannerella forsythia and Prevotella intermedia represent attractive

29 givalis, Treponema denticola, and Tannerella forsythia and some evidence supporting association of Pr

30 to determine the pathogenic potential of T. forsythia and the in vivo role of the BspA protein in pa

31 cell adherence and invasion properties of T. forsythia and the role of the cell surface-associated pr

32 ens (Porphyromonas gingivalis and Tannerella forsythia), and cancer risk were investigated.

33 ubglottic contamination by P. gingivalis, T. forsythia, and A. actinomycetemcomitans.

34 ct on subglottic levels of P. gingivalis, T. forsythia, and A. actinomycetemcomitans.

35 gingivalis, Treponema denticola, Tannerella forsythia, and Actinomyces naeslundii.

36 gingivalis, Treponema denticola, Tannerella forsythia, and Aggregatibacter actinomycetemcomitans in

37 gingivalis, Treponema denticola, Tannerella forsythia, and Aggregatibacter actinomycetemcomitans lev

38 ganisms Porphyromonas gingivalis, Tannerella forsythia, and Campylobacter rectus (P </=0.05).

39 ccus spp., members of the orange complex, T. forsythia, and certain non-oral pathogens were associate

40 dens, C. concisus, Prevotella nigrescens, T. forsythia, and Dialister pneumosintes.

41 odontal pathogens, such as P. nigrescens, T. forsythia, and E. corrodens, as well as C. concisus, C.

42 mitans, Porphyromonas gingivalis, Tannerella forsythia, and Fusobacterium nucleatum from subgingival

43 gingivalis, Treponema denticola, Tannerella forsythia, and Fusobacterium nucleatum to colonize the p

44 vels of Porphyromonas gingivalis, Tannerella forsythia, and Fusobacterium nucleatum using real time p

45 vels of Porphyromonas gingivalis, Tannerella forsythia, and Fusobacterium nucleatum were analyzed for

46 gatibacter actinomycetemcomitans, Tannerella forsythia, and Porphyromonas gingivalis was either absen

47 thogens Porphyromonas gingivalis, Tannerella forsythia, and Prevotella intermedia represent attractiv

48 such as Porphyromonas gingivalis, Tannerella forsythia, and Prevotella intermedia, were clustered int

49 parvula, Dialister pneumosintes, Tannerella forsythia, and Prevotella nigrescens than SUP sites from

50 diosum, Porphyromonas gingivalis, Tannerella forsythia, and Selenomonas sputigena species than PH sub

51 m fastidiosum, Filifactor alocis, Tannerella forsythia, and several Peptostreptococcus and Treponema

52 ucleatum, Actinomyces naeslundii, Tannerella forsythia, and Streptococcus gordonii) associated with d

53 P. gingivalis, P. intermedia, T. forsythia, and T. denticola were more prevalent in CP; h

54 s (RC) (Porphyromonas gingivalis, Tannerella forsythia, and T. denticola) in inducing disseminating i

55 obacterium, S-layer components in Tannerella forsythia, and tooth tissue-degrading enzymes in the ora

56 mitans, Porphyromonas gingivalis, Tannerella forsythia, and Treponema denticola were determined using

57 mitans, Porphyromonas gingivalis, Tannerella forsythia, and Treponema denticola.

58 onas micra, P. gingivalis, P. intermedia, T. forsythia, and Treponema denticola.

59 pithelial cell attachment and invasion by T. forsythia are dependent on the BspA protein.

60 givalis, Treponema denticola, and Tannerella forsythia are periodontal pathogens associated with the

61 zed that P. gingivalis, T. denticola, and T. forsythia are synergistic in terms of virulence potentia

62 ted with P. gingivalis, T. denticola, and T. forsythia as a consortium.

63 ted with P. gingivalis, T. denticola, and T. forsythia as a polymicrobial infection.

64 sion, evidence is presented in support of T. forsythia as an important organism involved in inducing

65 sp) nucleatum, ssp polymorphum or Tannerella forsythia as single or mixed species infection was deter

66 givalis, Treponema denticola, and Tannerella forsythia, as an oral lavage every other week for 12 wee

67 givalis, Treponema denticola, and Tannerella forsythia, as well as Actinomyces viscosus, Campylobacte

68 CLM succeeded in decreasing T. forsythia at 6 months (P < 0.05), but no antibiotic was

69 evels of P. gingivalis, T. denticola, and T. forsythia, but not A. actinomycetemcomitans, in subgingi

70 givalis, Treponema denticola, and Tannerella forsythia, by using in silico tools, since they are pote

71 Importantly, intact T. forsythia cells or outer membrane vesicles, both of whic

72 r, the interaction of Prevotella spp. and T. forsythia decreased the likelihood of an individual to b

73 Furthermore, mutant strains of T. forsythia, devoid of either mirolysin or karilysin, show

74 onas gingivalis, Prevotella spp., Tannerella forsythia, Dialister spp., Selenomonas spp., Catonella m

75 aera, Anaeroglobus geminatus, and Tannerella forsythia displayed significantly differential abundance

76 that F. nucleatum species synergize with T. forsythia during biofilm formation and pathogenesis.

77 givalis, Treponema denticola, and Tannerella forsythia for 12 weeks.

78 sum of Porphyromonas gingivalis, Tannerella forsythia (formally T. forsythensis), and Treponema dent

79 Tannerella forsythia (formerly Bacteroides forsythus) is one of the

80 emerged periodontopathic pathogen Tannerella forsythia (formerly Bacteroides forsythus), a Gram-negat

81 r of Porphyromonas gingivalis and Tannerella forsythia (formerly known as Bacteroides forsythus).

82 ern analysis of tissue extracts from zinnia, forsythia (Forsythia suspensa), tobacco (Nicotiana tabac

83 ject Porphyromonas gingivalis and Tannerella forsythia from intra-coronary-thrombi and subgingival-pl

84 ingivalis, Prevotella intermedia, Tannerella forsythia, Fusobacterium nucleatum, and total bacteria c

85 ence of Porphyromonas gingivalis, Tannerella forsythia, Fusobacterium nucleatum, Prevotella intermedi

86 mitans, Porphyromonas gingivalis, Tannerella forsythia, Fusobacterium nucleatum, Prevotella intermedi

87 ance in single species infection, whereas T. forsythia had no effect.

88 th database indicates that the S-layer of T. forsythia has a unique structure exhibiting no homology

89 givalis, Treponema denticola, and Tannerella forsythia have been strongly implicated as members of a

90 th either P. gingivalis, T. denticola, or T. forsythia in monomicrobial infections or with all three

91 kers, Streptococcus sanguinis and Tannerella forsythia in shisha smokers.

92 g of 70% of blood plasma, an abundance of T. forsythia in the bacterial biofilm can cause local inhib

93 P. gingivalis), and Tannerella forsythia (T. forsythia) in subglottic samples was determined using qu

94 ivalis, Campylobacter rectus, and Tannerella forsythia) in vascular, blood, and subgingival samples.

95 s of K1058, a paralogous MurNAc kinase of T. forsythia, in its unbound state and in complex with MurN

96 ng and Th2 cells play pathogenic roles in T. forsythia-induced alveolar bone destruction.

97 in TLR2 or STAT6 result in resistance to T. forsythia-induced alveolar bone loss.

98 studies from our laboratory revealed that T. forsythia induces periodontal bone loss in mice and that

99 Furthermore, T. forsythia infection causes a pronounced Th2 bias, eviden

100 Native Forsythia intermedia dirigent protein isoforms were addi

101 Pinoresinol-(+)-lariciresinol reductase from Forsythia intermedia was used as a template for primer c

102 ecoisolariciresinol into (-)-matairesinol in Forsythia intermedia, was purified >6,000-fold to appare

103 (+)-pinoresinol-forming dirigent protein in Forsythia intermedia, whereas the presence of a (-)-pino

104 Tannerella forsythia is a dysbiotic member of the human oral microb

105 Tannerella forsythia is a gram-negative anaerobe strongly associate

106 Tannerella forsythia is a Gram-negative oral anaerobe which contrib

107 Tannerella forsythia is a periodontopathogen that expresses miropin

108 Tannerella forsythia is a poorly studied pathogen despite being one

109 though the gram-negative anaerobe Tannerella forsythia is also a vital contributor to periodontal bon

110 owed that coinfection of F. nucleatum and T. forsythia is more potent than infection with either spec

111 ng recognized by all complement pathways, T. forsythia is resistant to killing by human complement, w

112 Tannerella forsythia is strongly associated with chronic periodonti

113 from the human periodontopathogen Tannerella forsythia, is the only bacterial MMP to have been charac

114 ed with periodontal health, while Tannerella forsythia, its closest phylogenetic neighbor, is strongl

115 iously characterized metalloproteinase of T. forsythia, karilysin.

116 Association between increased T. forsythia levels and periodontitis was observed only in

117 ted that P. gingivalis, T. denticola, and T. forsythia not only exist as a consortium that is associa

118 gival crevicular fluid samples containing T. forsythia obtained from patients with periodontitis.

119 ivalis, Treponema denticola, and "Tannerella forsythia" (opinion on name change from Tannerella forsy

120 (A. actinomycetemcomitans, P. gingivalis, T. forsythia, or C. rectus) were detected in subgingival sa

121 gatibacter actinomycetemcomitans, Tannerella forsythia, or Prevotella intermedia) versus those with o

122 P <0.001), P. gingivalis (P = 0.042), and T. forsythia (P <0.001) were significantly higher in smoker

123 dance levels of P. gingivalis (P = 0.59), T. forsythia (P = 0.83) and A. actinomycetemcomitans (P = 0

124 ndex (p=0.004), vaginal levels of Tannerella forsythia (p=0.01), serum C-reactive protein (p=0.01), a

125 A. actinomycetemcomitans, P. gingivalis, T. forsythia, P. intermedia, and total bacteria significant

126 terial loads of Porphyromonas gingivalis, T. forsythia, Parvimonas micra, and total bacterial load we

127 s from the host or microbial competitors, T. forsythia possesses a serpin-type proteinase inhibitor c

128 rsus 9.8 x 10(5) cells; P <0.01), Tannerella forsythia (previously T. forsythensis) (16.2 x 10(5) cel

129 s), Porphyromonas gingivalis, and Tannerella forsythia (previously T. forsythensis) in their subgingi

130 for Porphyromonas gingivalis and Tannerella forsythia (previously T. forsythensis) was statistically

131 ingivalis, Prevotella intermedia, Tannerella forsythia (previously T. forsythensis), and Treponema de

132 rmedia, Porphyromonas gingivalis, Tannerella forsythia (previously T. forsythensis), and Treponema de

133 ticola, Porphyromonas gingivalis, Tannerella forsythia (previously T. forsythensis), Prevotella inter

134 gingivalis, Treponema denticola, Tannerella forsythia (previously T. forsythensis), Prevotella inter

135 comitans], Prevotella intermedia, Tannerella forsythia [previously T. forsythensis], Fusobacterium nu

136 unts of Porphyromonas gingivalis, Tannerella forsythia, Prevotella intermedia (Pi), and Treponema den

137 tpartum, levels of P. gingivalis, Tannerella forsythia, Prevotella intermedia, and Prevotella nigresc

138 mitans, Porphyromonas gingivalis, Tannerella forsythia, Prevotella intermedia, Prevotella nigrescens,

139 mutans, Porphyromonas gingivalis, Tannerella forsythia, Prevotella intermedia, Treponema denticola, a

140 Mean levels of P. gingivalis (r = 0.68), T. forsythia (r = 0.62), F. alocis (r = 0.51, P = 0.001), a

141 um with karilysin, a metalloproteinase of T. forsythia, resulted in a decrease in bactericidal activi

142 The present study shows that the T. forsythia S-layer is very unique, since it appears to be

143 viduals had higher proportions of Tannerella forsythia, Selenomonas noxia, and Neisseria mucosa.

144 that regulates the activity of endogenous T. forsythia serine proteases.

145 Porphyromonas gingivalis (Pg) and Tannerella forsythia, stimulate cytokine production in human monocy

146 T. forsythia strains expressing karilysin at higher levels

147 s of tissue extracts from zinnia, forsythia (Forsythia suspensa), tobacco (Nicotiana tabacum), alfalf

148 ata show that F. nucleatum subspecies and T. forsythia synergistically stimulate the host immune resp

149 s gingivalis (P. gingivalis), and Tannerella forsythia (T. forsythia) in subglottic samples was deter

150 or Treponema denticola (T.d.) and Tannerella forsythia (T.f.), 2.5 x 10(4) for Porphyromonas gingival

151 ll Socransky red bacteria (P. gingivalis, T. forsythia, T. denticola).

152 Key pathogens P. gingivalis, T. forsythia, T. denticola, P. micra, C. rectus, and E. nod

153 ences were significant for P. gingivalis, T. forsythia, T. denticola, P. micra, C. rectus, and E. nod

154 Porphyromonas gingivalis and Tannerella forsythia (Tannerella forsythensis) were associated with

155 Tannerella forsythia (Tf) is a Gram-negative anaerobe implicated in

156 s (Pg), Treponema denticola (Td), Tannerella forsythia (Tf), Aggregatibacter actinomycetemcomitans, a

157 (Pg), Prevotella intermedia (Pi), Tannerella forsythia (Tf), and Fusobacterium nucleatum (Fn).

158 acter actinomycetemcomitans (Aa), Tannerella forsythia (Tf), and gingival crevicular fluid (GCF) conc

159 of Porphyromonas gingivalis (Pg), Tannerella forsythia (Tf), and Treponema denticola (Td) was perform

160 Porphyromonas gingivalis (Pg) and Tannerella forsythia (Tf), endogenous oral pathogens, direct the RA

161 Quantification of Tannerella forsythia (Tf), Porphyromonas gingivalis (Pg), Aggregati

162 s, Porphyromonas gingivalis (Pg), Tannerella forsythia (Tf), Treponema denticola (Td), and Dialister

163 ), Campylobacter rectus (Cr), and Tannerella forsythia (Tf).

164 the enzymes from P. gingivalis (PgQC) and T. forsythia (TfQC) reveal a tertiary structure composed of

165 gingivalis, A. actinomycetemcomitans, and T. forsythia than never-smokers.

166 s of Porphyromonas gingivalis and Tannerella forsythia than NW patients (P <0.05).

167 We found the periodontal pathogen Tannerella forsythia to be associated with higher risk of EAC.

168 Vs enhance the attachment and invasion of T. forsythia to epithelial cells.

169 xylem fibers, and phloem fibers in stems of forsythia, tobacco, alfalfa, soybean, and tomato (Lycope

170 was evident in xylem ray parenchyma cells of forsythia, tobacco, and tomato.

171 ncisus, Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola, and Candida albicans.

172 mitans, Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola, and Prevotella intermedi

173 mitans, Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola, and Streptococcus oralis

174 mitans, Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola, Fusobacterium nucleatum

175 Significant reduction in Tannerella forsythia, Treponema denticola, Fusobacterium nucleatum,

176 mitans, Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola, Streptococcus oralis, an

177 h as Porphyromonas gingivalis and Tannerella forsythia, use disulfide bonds to stabilize their outer

178 ction of the periodontal pathogen Tannerella forsythia, (v) 239 bacterial and 43 human proteins, allo

179 Tannerella forsythia was significantly reduced in both groups at 3

180 skii, Dialister pneumosintes, and Tannerella forsythia were elevated in this group, while Veillonella

181 as gingivalis, Prevotella intermedia, and T. forsythia were significantly more present around implant

182 etween groups were only found for Tannerella forsythia, which was 8.7 times more frequent at peri-imp

183 timidum, Fretibacterium spp., and Tannerella forsythia, while Actinomyces naeslundii and Streptococcu

184 as gingivalis (P. gingivalis) and Tannerella forsythia who completed initial therapy were randomly as

185 eolar bone loss in mice infected with the T. forsythia wild-type strain, whereas the BspA mutant was

186 periodontal health-associated" taxon with T. forsythia will be valuable in investigating virulence fa

187 d by the long and intimate association of T. forsythia with the human gingiva.