ライフサイエンスコーパス: G protein-coupled receptor

1 lucogenic effect through OR4M1, an olfactory G-protein-coupled receptor.

2 ltiscale modeling in exploring the action of G protein-coupled receptors.

3 cell migration by activating a family of 23 G protein-coupled receptors.

4 Melatonin (Mel) promotes sleep through G protein-coupled receptors.

5 ng cascades triggered by the 7-transmembrane G protein-coupled receptors.

6 tivity toward EPAC over protein kinase A and G protein-coupled receptors.

7 erged as key regulators of signaling through G protein-coupled receptors.

8 by the interactions of chemokines with their G protein-coupled receptors.

9 subset of oxylipins and is signaled through G-protein coupled receptors.

10 in each proximal tubule group, including 145 G-protein-coupled receptors.

11 nsights into the activation of G-proteins by G-protein-coupled receptors.

12 ignaling and signaling downstream from other G-protein-coupled receptors.

13 rning the original roles for these classical G-protein-coupled receptors.

14 ection of two putative fatty acid receptors, G protein-coupled receptor 120 (GPR120) and cluster of d

15 anaesthetics(10), neurotransmitters(13) and G-protein-coupled receptors(13).

16 ified heterozygous germline mutations in the G protein-coupled receptor 161 (GPR161) gene in six pati

17 G protein-coupled receptor 27 (Gpr27) is an orphan GPCR

18 balance via several nuclear receptors and/or G-protein-coupled receptors(3,4).

19 more complicated with the identification of G protein-coupled receptor 30 (GPR30), an estrogen recep

20 Pamoic acid is a potent ligand for G protein Coupled Receptor 35 (GPR35) and exhibits antin

21 a-catenin and leucine rich repeat containing G protein-coupled receptor 4 (LGR4) and LGR5 receptors.

22 us ligands of leucine-rich repeat-containing G-protein-coupled receptor 4 (LGR4).

23 The butyrate-G-protein-coupled receptor 43-GLP-1 pathway in the intes

24 ria, supports leucine-rich repeat-containing G protein-coupled receptor 5 (LGR5)(+) intestinal stem c

25 derived from leucine-rich repeat-containing G protein-coupled receptor 5 (LGR5)-positive adult stem

26 The G protein-coupled receptor 52 (GPR52) is an orphan recep

27 ed within the leucine-rich repeat-containing G-protein coupled receptor 6 (LGR6) (FDR = 0.0002).

28 qRT-PCR analysis indicated the expression of G-protein-coupled receptor 68 gene (Gpr68) and acid-sens

29 Increasing evidence implicates the orphan G protein-coupled receptor 88 (GPR88) in a number of str

30 sed over 30 years ago to explain how diverse G protein-coupled receptors achieve specificity despite

31 We therefore developed red fluorescent G-protein-coupled receptor-activation-based DA (GRAB(DA)

32 A role for the adhesion G-protein coupled receptor ADGRE2 or EMR2 in mechanosens

33 Adhesion G protein-coupled receptor ADGRG1/GPR56 controls multipl

34 Adhesion G protein-coupled receptors (AGPCRs) are a thirty-three-

35 Adhesion G protein-coupled receptors (aGPCRs) are key cell-surfac

36 The experimental evidence that Adhesion G Protein-Coupled Receptors (aGPCRs) functionally couple

37 e and alternatively-spliced ECRs of adhesion G protein-coupled receptors (aGPCRs) have key functions

38 ceptor (VIP1R) is a widely expressed class B G protein-coupled receptor and a drug target for the tre

39 Rex1, activates Rac1 signaling downstream of G protein-coupled receptors and PI3K.

40 ilon (PLCepsilon) is activated downstream of G protein-coupled receptors and receptor tyrosine kinase

41 standing the mechanism by which it regulates G protein-coupled receptors and will aid in elucidating

42 ction of cAMP, independent of alterations in G protein-coupled receptors and/or G proteins.

43 Specifically, they express G-protein-coupled receptors and functional innate immune

44 -Adrenoceptors (beta(2)-AR) are prototypical G-protein-coupled receptors and important pharmacologica

45 g(2+) may be a phenomenon occurring in other G-protein-coupled receptors and, therefore, potentially

46 uble protein calmodulin, ligand binding to a G protein-coupled receptor, and activation of an ion cha

47 nisms seen in structurally analogous class A G protein-coupled receptors, and Smoothened.

48 Disruptions of GPR4, a pH-sensing G-protein coupled receptor, and DBT, a subunit of the br

49 GABA(B) belongs to class C of the G-protein-coupled receptors, and its functional entity c

50 G protein-coupled receptors are critical mediators of pl

51 G protein-coupled receptors are important regulators of

52 Class B G-protein-coupled receptors are major targets for the tr

53 The opsin family of G-protein-coupled receptors are used as light detectors

54 84 is a medium chain free fatty acid-binding G-protein-coupled receptor associated with inflammatory

55 Here, we report that G-protein-coupled receptor-associated sorting proteins (

56 y differs considerably from that employed by G protein-coupled receptors at the plasma membrane.

57 neutralizing a variety of known circulating G-protein coupled receptor autoantibodies.

58 ndent on epigenetic reactivation of adhesion G-protein-coupled receptor B1 (BAI1/ADGRB1), a tumor sup

59 tentiate TRPV1 activity during activation of G protein-coupled receptors, but it is not known whether

60 ccelerators for activated Galpha subunits of G-protein coupled receptors, but they may also modulate

61 essin signaling is initiated by binding to a G-protein-coupled receptor called V2R, which signals thr

62 he specific function of SMC-expressed orphan G protein-coupled receptor class C group 5 member B (GPR

63 G-protein-coupled receptor class 5 member D (GPRC5D) is

64 are mediated by the class B calcitonin-like G protein-coupled receptor (CLR), which heterodimerizes

65 nderstanding of ligand-gated ion channel and G protein-coupled receptor complexes and discuss strateg

66 The class Frizzled (FZD) or class F of G protein-coupled receptors consists of 10 FZD paralogue

67 uncover a multi-RhoGEF complex downstream of G-protein-coupled receptors controlling CDC42-RHOA cross

68 rane bundle represent the mechanism by which G-protein-coupled receptors convert an extracellular che

69 lored if ligands of therapeutically relevant G-protein-coupled receptors could be discovered by struc

70 g mutation in CYSLTR2, the gene encoding the G protein-coupled receptor cysteinyl-leukotriene recepto

71 PAR1 is a G-protein-coupled receptor densely expressed in the CNS,

72 Biased agonism at G protein-coupled receptors describes the phenomenon whe

73 CYSLTR2 is the first known example of a G protein-coupled receptor driver oncogene that encodes

74 d receptors (ORs) are among the best-studied G protein-coupled receptors due to their involvement in

75 perinsulinemia and hyperglycemia through the G-protein coupled receptor ERV1/ChemR23.

76 Histamine binds to one of the four G-protein-coupled receptors expressed by large cholangio

77 GPR56, a member of the adhesion G protein-coupled receptor family, is abundantly express

78 tty acid receptor-4 (FFA4) is a cell-surface G protein-coupled receptor for medium and long-chained f

79 GPBAR1 is a G protein-coupled receptor for secondary bile acids plac

80 ino-mediated knockdown of GPR31, a purported G-protein-coupled receptor for 12-HETE, largely phenocop

81 GPR81 is a G-protein-coupled receptor for lactate, which is upregul

82 The G protein-coupled receptors Frizzled(1-10) (FZD(1-10)) a

83 knowledge, the first experimental model of a G-protein-coupled receptor-G-protein complex embedded in

84 rologous adaptations in kinase regulation of G protein coupled receptor (GPCR) desensitization.

85 Gpr27 is a highly conserved, orphan G protein coupled receptor (GPCR) previously implicated

86 PGCs utilize a G protein coupled receptor (GPCR), Tre1, to guide front-

87 nergic receptor (beta(2)AR) is an archetypal G protein coupled receptor (GPCR).

88 Membrane trafficking processes regulate G protein-coupled receptor (GPCR) activity.

89 - and structure-based discovery strategy for G protein-coupled receptor (GPCR) biased drug screening.

90 G protein-coupled receptor (GPCR) biogenesis, traffickin

91 The class B G protein-coupled receptor (GPCR) calcitonin receptor (C

92 The chemokine receptor CXCR4, a G protein-coupled receptor (GPCR) capable of heteromeriz

93 GPR88 is an orphan G protein-coupled receptor (GPCR) considered as a promis

94 tagonistic activities against a panel of 168 G protein-coupled receptor (GPCR) drug targets.

95 The dopamine D2 receptor (D2R) is a G protein-coupled receptor (GPCR) expressed in regions o

96 gII) type 1 receptor (AT1R), a member of the G protein-coupled receptor (GPCR) family, signals throug

97 tor-4 (FFA4), previously termed GPR120, is a G protein-coupled receptor (GPCR) for medium and long-ch

98 the free N-terminal fragment of the adhesion G protein-coupled receptor (GPCR) GPR56 in human plasma

99 The orphan G protein-coupled receptor (GPCR) GPR84 is expressed on

100 like peptide-1 receptor (GLP1R) is a class B G protein-coupled receptor (GPCR) involved in metabolism

101 identified novel eNOS interactors, including G protein-coupled receptor (GPCR) kinase interactor 1 (G

102 G protein-coupled receptor (GPCR) kinases (GRKs) play a

103 oping antibodies as functional modulators of G protein-coupled receptor (GPCR) signaling for both the

104 ign 'biased' drugs that selectively activate G protein-coupled receptor (GPCR) signaling pathways ben

105 me label-free techniques are used to profile G protein-coupled receptor (GPCR) signaling pathways in

106 ng techniques has revealed that mutations in G protein-coupled receptor (GPCR) signaling pathways in

107 or some agonists to preferentially stimulate G protein-coupled receptor (GPCR) signaling through one

108 pect to the activation of striatal astrocyte G protein-coupled receptor (GPCR) signaling.

109 R5) is a chemokine receptor belonging to the G protein-coupled receptor (GPCR) superfamily.

110 ting chemokine receptors which belong to the G protein-coupled receptor (GPCR) superfamily.

111 D2R is a G protein-coupled receptor (GPCR) that activates G prote

112 de hormone glucagon is a seven-transmembrane G protein-coupled receptor (GPCR) that regulates blood g

113 commonly used opioids, and is a prototypical G protein-coupled receptor (GPCR) where new pharmacologi

114 psin3 (Opn3) is a transmembrane heptahelical G protein-coupled receptor (GPCR) with the potential to

115 istasis within the binding pocket of a human G protein-coupled receptor (GPCR) yielding variants with

116 ts of a nanobody and a peptidic ligand for a G protein-coupled receptor (GPCR), fused via their C-ter

117 A novel human G protein-coupled receptor (GPCR), known as Mas-related

118 NTSR1, a G protein-coupled receptor (GPCR), signals through the c

119 MC4R is revealed as a structurally divergent G protein-coupled receptor (GPCR), with more similarity

120 dopsin is a canonical class A photosensitive G protein-coupled receptor (GPCR), yet relatively few ph

121 r may be GPR89, putatively an ion channel or G protein-coupled receptor (GPCR).

122 e diversity and near universal expression of G protein-coupled receptors (GPCR) reflects their involv

123 maceutical drugs targeting integral membrane G protein-coupled receptors (GPCR) requires thorough und

124 Among class A G protein-coupled receptors (GPCR), the human adenosine

125 Although comprehensively recognized for the G protein-coupled receptors (GPCR), this process is scar

126 he purification and analysis of a functional G-protein coupled receptor (GPCR).

127 angiogenic growth factors, acting via RTK or G-protein coupled receptors (GPCR), may mediate VEGF inh

128 intracellular signaling pathways, including G-protein coupled-receptor (GPCR)-mediated calcium signa

129 Here we show that GPR151, an orphan G-protein-coupled receptor (GPCR) highly enriched in the

130 lso known as ACKR3, is a seven-transmembrane G-protein-coupled receptor (GPCR) involved in various pa

131 The beta(1)-adrenoceptor (beta(1)AR) is a G-protein-coupled receptor (GPCR) that couples(1) to the

132 combined activation mechanism for a class B G-protein-coupled receptor (GPCR), the glucagon receptor

133 the proteolytically-activated PAR family of G-protein-coupled receptors (GPCR) that represents an im

134 trimeric guanine nucleotide-binding protein (G protein)-coupled receptors (GPCRs) play important role

135 Many endogenous peptides activate G protein-coupled receptors (GPCRs) - nearly 50 GPCR pep

136 Agonist binding promotes activation of G protein-coupled receptors (GPCRs) and association of a

137 K2), an important negative modulator of both G protein-coupled receptors (GPCRs) and insulin signalin

138 Osteocytes express numerous G protein-coupled receptors (GPCRs) and thus mice lackin

139 G protein-coupled receptors (GPCRs) are a large family o

140 G protein-coupled receptors (GPCRs) are biologic switche

141 These G protein-coupled receptors (GPCRs) are broadly expresse

142 G protein-coupled receptors (GPCRs) are crucial for esta

143 G protein-coupled receptors (GPCRs) are important membra

144 G protein-coupled receptors (GPCRs) are important modula

145 G protein-coupled receptors (GPCRs) are important pharma

146 Class B G protein-coupled receptors (GPCRs) are important therap

147 G protein-coupled receptors (GPCRs) are membrane-bound p

148 G protein-coupled receptors (GPCRs) are privileged struc

149 G protein-coupled receptors (GPCRs) are prominent target

150 The >800 human G protein-coupled receptors (GPCRs) are responsible for

151 Multiple G protein-coupled receptors (GPCRs) are targets in the t

152 G protein-coupled receptors (GPCRs) are the largest clas

153 G protein-coupled receptors (GPCRs) are the most common

154 G protein-coupled receptors (GPCRs) are vital for divers

155 The phosphorylation of G protein-coupled receptors (GPCRs) by GPCR kinases (GRK

156 Formylpeptide receptors (FPRs) as G protein-coupled receptors (GPCRs) can recognize formyl

157 G protein-coupled receptors (GPCRs) comprise a large cla

158 G protein-coupled receptors (GPCRs) comprise the largest

159 More than 800 G protein-coupled receptors (GPCRs) comprise the largest

160 Regulated trafficking of G protein-coupled receptors (GPCRs) controls cilium-base

161 How G protein-coupled receptors (GPCRs) evoke specific biolo

162 Structures of 70 unique G protein-coupled receptors (GPCRs) have been determined

163 A variety of G protein-coupled receptors (GPCRs) have been implicated

164 Of the 800 G protein-coupled receptors (GPCRs) in humans, only thre

165 G protein-coupled receptors (GPCRs) initiate signaling c

166 The interplay between G protein-coupled receptors (GPCRs) is critical for cont

167 Agonist-activated G protein-coupled receptors (GPCRs) must correctly selec

168 Dynamic trafficking of G protein-coupled receptors (GPCRs) out of cilia is medi

169 Biased agonists of G protein-coupled receptors (GPCRs) preferentially activ

170 G protein-coupled receptors (GPCRs) represent the larges

171 G protein-coupled receptors (GPCRs) signal through allos

172 nsduce and amplify the cellular signals from G protein-coupled receptors (GPCRs) to intracellular eff

173 G protein-coupled receptors (GPCRs) typically induce end

174 Despite the medical importance of G protein-coupled receptors (GPCRs), in vivo cellular he

175 uctural and spectroscopic studies of class A G protein-coupled receptors (GPCRs), such as rhodopsin a

176 st-based reporter strains for studying human G protein-coupled receptors (GPCRs), the largest class o

177 s ligand bias has been studied primarily for G protein-coupled receptors (GPCRs), there are also repo

178 leotides through the P2Y class of purinergic G protein-coupled receptors (GPCRs), which stimulate int

179 rane domain has close structural homology to G protein-coupled receptors (GPCRs).

180 orphanization" of candidate oocyte-expressed G protein-coupled receptors (GPCRs).

181 G-protein coupled receptors (GPCRs) represent a signific

182 neer highly selective compounds for targeted G-protein coupled receptors (GPCRs) with optimized effic

183 ion frequency, RNA-i against seven out of 35 G-protein coupled receptors (GPCRs) within the germline

184 y a central role in modulating signaling via G-protein coupled receptors (GPCRs).

185 ts complications, and demonstrate a role for G-protein coupled-receptors (GPCRs) that sense gut metab

186 G-protein-coupled receptors (GPCRs) are a ubiquitously e

187 G-protein-coupled receptors (GPCRs) are allosteric signa

188 G-protein-coupled receptors (GPCRs) are divided phylogen

189 G-protein-coupled receptors (GPCRs) are involved in nume

190 G-protein-coupled receptors (GPCRs) are major signaling

191 G-protein-coupled receptors (GPCRs) are membrane protein

192 Peptide drugs targeting class B1 G-protein-coupled receptors (GPCRs) can treat multiple d

193 G-protein-coupled receptors (GPCRs) comprise the largest

194 Binding of arrestin to phosphorylated G-protein-coupled receptors (GPCRs) controls many aspect

195 High-resolution structural studies on G-protein-coupled receptors (GPCRs) have flourished rece

196 The extracellular domain (ECD) of class B1 G-protein-coupled receptors (GPCRs) plays a central role

197 After activation by an agonist, G-protein-coupled receptors (GPCRs) recruit beta-arresti

198 dications targeting this family of proteins, G-protein-coupled receptors (GPCRs) remain invaluable th

199 eurons that express the structurally related G-protein-coupled receptors (GPCRs) TACR1 and GPR83 form

200 ity-modifying proteins (RAMPs) interact with G-protein-coupled receptors (GPCRs) to modify their func

201 Agonist stimulation of G-protein-coupled receptors (GPCRs) typically leads to p

202 lpha(q) places an entire signaling branch of G-protein-coupled receptors (GPCRs) under hierarchical c

203 ch third intracellular loop (TIL) of various G-protein-coupled receptors (GPCRs), and it is unclear w

204 stin proteins bind to active, phosphorylated G-protein-coupled receptors (GPCRs), thereby preventing

205 ) receptor-a member of the class C family of G-protein-coupled receptors (GPCRs)-mediates inhibitory

206 diponectin receptors and opposite to that of G-protein-coupled receptors (GPCRs).

207 s metazoan opsins, which are light-activated G-protein-coupled receptors (GPCRs).

208 ve autoantibodies (AAs) recognize a range of G-protein-coupled receptors (GPCRs).

209 ting CRF1R and CRF2R, two members of class B G-protein-coupled receptors (GPCRs).

210 G protein-coupled receptor (GPR) 55 is a putative cannab

211 activated-receptor alpha (PPARalpha) and the G-protein coupled receptor, GPR119] and upstream (a fatt

212 cus, we identified a gene encoding an orphan G-protein-coupled receptor, Gpr12, which is sufficient t

213 in wild-type and recipient mice lacking the G protein-coupled receptor GPR43 (the metabolite-sensing

214 and knockout mice lacking the genes encoding G protein-coupled receptors GPR43 or GPR109A.

215 In cells expressing G-protein-coupled receptor GPR55, GDE3 abolished 1-acyl

216 teins, such as ligand-gated ion channels and G protein-coupled receptors, has directly enabled the di

217 Rhodopsin is the G protein-coupled receptor in rod photoreceptor cells th

218 Despite the roles of G protein-coupled receptors in thymocyte emigration, the

219 ical and chemical definition of signaling by G-protein-coupled receptors in kinetic terms.

220 al epithelium that regulates the activity of G-protein-coupled receptors, in asthma.

221 eveal PAGln mediates cellular events through G-protein coupled receptors, including alpha2A, alpha2B,

222 Association of G protein-coupled receptors into heterodimeric complexes

223 uggesting that the pathway activated by this G-protein-coupled receptor is causing light-induced phot

224 member of the family of chemokine-activated G protein-coupled receptors, is widely expressed in immu

225 5-HT(2A,) a G-protein coupled receptor, is widely expressed in the h

226 phosphorylation of its carboxyl terminus by G protein-coupled receptor kinase 1 (GRK1).

227 Here, we identified G protein-coupled receptor kinase 2 (GRK2) as a new MALT

228 ed decrease in the hepatic protein levels of G protein-coupled receptor kinase 2 (GRK2), an important

229 rase 4D (PDE4D) through transactivation of a G protein-coupled receptor kinase 2 (GRK2)-dependent bet

230 e-specific expression of a dominant-negative G protein-coupled receptor kinase 2 (GRK2-DN) transgene

231 Persistently increased activity of G protein-coupled receptor kinase 4 (GRK4), caused by in

232 We demonstrate that G protein-coupled receptor kinase 5 (GRK5) promotes plat

233 rylation of FFA4-L is primarily regulated by G protein-coupled receptor kinase 6, whereas protein kin

234 e desensitization through phosphorylation by G protein-coupled receptor kinase is supported in tissue

235 G protein-coupled receptor kinases (GRKs) are attractive

236 peptides and leucine-rich repeat-containing, G protein-coupled receptors (LGR) were revealed.

237 cells lacking leucine-rich repeat-containing G-protein coupled receptors (LGRs) 4, 5 and 6 (Lebensohn

238 G-protein-coupled receptors like the human Y(1) receptor

239 to-oncogene Mas receptor and the Mas-related G protein-coupled receptor member D.

240 ocated CD301b(+) DCs through the Mas-related G-protein coupled receptor member A1 (MRGPRA1).

241 vious work demonstrated that the presynaptic G protein-coupled receptor metabotropic glutamate recept

242 tributes to PF-PC LTP.SIGNIFICANCE STATEMENT G-protein-coupled receptors modulate the release machine

243 fold is a promising scaffold for developing G protein-coupled receptor modulators.

244 logical functions through the actions of two G-protein-coupled receptors: MT(1) and MT(2).

245 Agonists to the mu-opioid G protein-coupled receptor (muOR) can alleviate pain thr

246 s neuropeptide FF (NPFF) and its two cognate G protein-coupled receptors, Neuropeptide FF Receptors 1

247 t discovery of sensory (tastant and odorant) G protein-coupled receptors on the smooth muscle of huma

248 ron loaded peptide conjugates, which address G protein-coupled receptors overexpressed on tumor cells

249 The orexin system, which consists of the two G protein-coupled receptors OX(1) and OX(2), activated b

250 uropeptides that activate the rhodopsin-like G protein-coupled receptors OX1R and OX2R.

251 timulated hypertrophic signals by activating G protein-coupled receptors, particularly, the olfactory

252 RNAseq reveals changes in amine- and G-protein coupled receptor pathways.

253 o and in vivo and that GPRC5B, but not other G protein-coupled receptors, physically interacts with I

254 ransient receptor potential ion channels and G-protein coupled receptors play important roles in itch

255 hich different ligands that bind to the same G protein-coupled receptor preferentially trigger distin

256 Here we show that targeting a specific G-protein coupled receptor promotes senescence in synovi

257 prove specificity and reduce side effects of G protein-coupled receptor-related therapies.

258 G Protein-Coupled receptors represent the main communica

259 Screening of ML417 against multiple G protein-coupled receptors revealed exceptional global

260 electrophysiological analyses of the retinal G-protein-coupled receptor (RGR) suggest that it could s

261 y member responsible for inactivation of the G protein-coupled receptor rhodopsin in photoreceptors.

262 G protein coupled receptors signal through G proteins or

263 Whether G protein-coupled receptors signal from endosomes to con

264 enes involved with the extracellular matrix, G protein-coupled receptor signaling and lipid metabolis

265 focuses on delineating relationships between G protein-coupled receptor signaling and trafficking in

266 G protein-coupled receptor signaling is required for the

267 Biasing G protein-coupled receptor signaling with ligands that p

268 amino acids; the calcium-sensing receptor (a G protein-coupled receptor) signalling pathway; and the

269 Here, we generalize this concept to a G protein-coupled receptor, somatostatin receptor subtyp

270 contraction, whereas signaling downstream of G-protein-coupled receptors stimulates Ca(2+) release vi

271 id epidemic represents a central question to G protein coupled receptor structural biology and pharma

272 G-protein-coupled receptor SUCNR1 (succinate receptor 1

273 pocket and the G-protein-binding site in the G-protein-coupled receptor superfamily.

274 noma(2) and modulate host metabolism via the G-protein-coupled receptor TGR5 (ref.

275 Orexin receptors are G protein coupled receptors that may be useful targets f

276 ike peptide-1 receptor (GLP-1R) is a class B G protein-coupled receptor that plays an important role

277 a pivotal role in the regulation of several G protein-coupled receptors that are essential for energ

278 The orexin receptors are peptide-sensing G protein-coupled receptors that are intimately linked w

279 ncer that centers on a negative regulator of G protein-coupled receptors that is downregulated in agg

280 GPRC6A is a widely expressed G-protein coupled receptor that regulates energy metabol

281 GPR18 is a G-protein-coupled receptor that belongs to the orphan cl

282 GPR52 is a class-A orphan G-protein-coupled receptor that is highly expressed in t

283 receptors (PARs) are a four-member family of G-protein-coupled receptors that are activated via prote

284 ous system development, including a suite of G-protein-coupled receptors that control physiology and

285 ar loops and the intracellular region of the G-protein-coupled receptors that interacts with G-protei

286 In contrast to most rhodopsin-like G protein-coupled receptors, the glycoprotein hormone re

287 ntify signaling mechanisms downstream from a G-protein-coupled receptor, the vasopressin V2 subtype r

288 Besides being regulated by G-protein-coupled receptors, the activity of heterotrime

289 ics of signaling are of increasing value for G-protein-coupled receptor therapeutic development, incl

290 and, given that this peptide signals through G-protein coupled receptors, this signalling pathway pro

291 re mediated largely through their downstream G-protein coupled receptors through cAMP-PKA signaling.

292 proteins communicate signals from activated G protein-coupled receptors to downstream effector prote

293 n that is responsible for the trafficking of G-protein-coupled receptors to cilia and whose aberrant

294 licit host production of mediators acting on G-protein-coupled receptors to regulate airway tone.

295 We previously showed the HCMV-encoded G protein-coupled receptor US28 is expressed during late

296 t activation, but not activation mediated by G-protein-coupled receptors, was strongly dependent on t

297 g cholangiocyte proliferation via GHS-R1a, a G-protein coupled receptor which causes increased intrac

298 sual rhodopsin is an important archetype for G-protein-coupled receptors, which are membrane proteins

299 GABA(B) belongs to family C of the G-protein-coupled receptors, which operate as dimers to

300 Mas-related G protein-coupled receptor X2 (MRGPRX2) is regarded as a