ライフサイエンスコーパス: GABA(B) receptor agonist

1 astric distension that could be rescued with GABA(B) receptor agonist.

2 30 mg of arbaclofen (STX209), a GABA type B (GABA(B)) receptor agonist.

3 thing medium or mimicked by adding baclofen (GABA(B) receptor agonist; 100 microM) to normally-record

4 Baclofen, a GABAB receptor agonist, activated G-protein gated inward

5 ]CGP54626 was inhibited by several mammalian GABA(B) receptor agonists and antagonists.

6 To explore this possibility a number of GABAB receptor agonists and antagonists were examined fo

7 and DMS with muscimol+baclofen (GABA(a) and GABA(b) receptor agonists) and then tested them for rela

8 promoted by 4-aminopyridine and inhibited by GABA(B) receptor agonists, and appears far more sensitiv

9 quantify the relative binding affinities of GABA(B) receptor agonists, antagonists and the effect of

10 Application of either GABA(A) or GABA(B) receptor agonists attenuated the colonic afferen

11 Effects of spinal administration of the GABA(B) receptor agonist baclofen (0.1-10 microg/50 micr

12 The GABA(B) receptor agonist baclofen (20 mum) enhanced GABA

13 u-opioid receptor agonist DAMGO (93%) or the GABA(B) receptor agonist baclofen (83%) with a membrane

14 arizing response of GABAergic neurons to the GABA(B) receptor agonist baclofen 24 hr after treatment.

15 In C57BL/6 mice, pretreatment with GABA(B) receptor agonist baclofen blocked the rewarding

16 ent with a subthreshold concentration of the GABA(B) receptor agonist baclofen blocks ethanol but not

17 The GABA(B) receptor agonist baclofen decreased the rate of

18 The GABA(B) receptor agonist baclofen facilitates the extinc

19 L-type Ca(2+) channel current induced by the GABA(B) receptor agonist baclofen or by guanosine 5'-3-O

20 of VDCCs nor their inhibition by either the GABA(B) receptor agonist baclofen or intracellular guano

21 With G-protein inhibition induced by the GABA(B) receptor agonist baclofen or the adenosine A1 re

22 -estradiol (E(2)) reduced the potency of the GABA(B) receptor agonist baclofen to activate G protein-

23 crease in intracellular calcium, whereas the GABA(B) receptor agonist baclofen was ineffective, sugge

24 values and a GIRK-dependent response to the GABA(B) receptor agonist baclofen, but not DAMGO.

25 mitter release from POMC neurons, as did the GABA(B) receptor agonist baclofen.

26 In contrast, the GABAB receptor agonist baclofen (1-100 microM) exerted a

27 GABA and the GABAB receptor agonist baclofen activated a potassium co

28 The GABAB receptor agonist baclofen also inhibited inward cu

29 Simultaneous injection of the GABAB receptor agonist baclofen at doses of 2.5, 5.0 and

30 ong-term ( approximately 5 years) use of the GABAb receptor agonist baclofen by SCI patients reduced

31 used by a lack of GIRK activity, because the GABAB receptor agonist baclofen continued to elicit thes

32 ne methiodide had little effect, whereas the GABAB receptor agonist baclofen dramatically attenuated

33 f the GABAA receptor agonist muscimol or the GABAB receptor agonist baclofen elicited intense, dose-r

34 The orthosteric GABAB receptor agonist baclofen has been shown to suppre

35 E2 reduced rapidly the potency of the GABAB receptor agonist baclofen to activate G-protein-co

36 ve activation, are minimally affected by the GABAB receptor agonist baclofen, and express NMDA recept

37 ted the effects of estrogen on DAMGO- or the GABAB receptor agonist baclofen-stimulated [35S]GTPgamma

38 eed, the calcium influx was inhibited by the GABAB receptor agonist baclofen.

39 sitivity of SOM-IPSCs, but not PV-IPSCs to a GABAb receptor agonist baclofen.

40 ulation of astrocytes, or application of the GABAB-receptor agonist baclofen, potentiated miniature i

41 a 5-HT2C receptor antagonist (SB242084) or a GABAB receptor agonist (baclofen), but not a GABAA recep

42 s were reversibly inhibited by the selective GABA(B) receptor agonists (+/-)-baclofen or CGP 27492 (1

43 The GABA(B) receptor agonist (-)-baclofen (5-10 microM) depr

44 Systemic administration of the GABA(B) receptor agonist, baclofen (10 mg/kg, i.p.), sig

45 In young animals, the GABA(B) receptor agonist, baclofen, inhibited the amplit

46 Baclofen is a GABAB receptor agonist commonly used to relief spasticit

47 lcium Green-1 dextran revealed that 5HT1 and GABA(B) receptor agonists decreased presynaptic calcium

48 Whereas GABAB receptor agonists exert a significant effect on ci

49 The application of GABAB receptor agonists failed to affect the membrane pr

50 ivity marker Fos, muscimol-baclofen (GABAa + GABAb receptor agonists) global inactivation, Daun02-sel

51 Application of baclofen, a specific GABA(B) receptor agonist, inhibited significantly neuron

52 Using microinjections of GABA(A) + GABA(B) receptor agonists (muscimol + baclofen) in media

53 nally, we used local infusion of GABA(A) and GABA(B) receptor agonists (muscimol + baclofen) to show

54 ect of LH reversible inactivation by GABAA + GABAB receptor agonists (muscimol + baclofen) on this ef

55 versible inactivation of CeA or BLA by GABAA+GABAB receptor agonists (muscimol+baclofen, 0.03+0.3 nmo

56 e protective effect of baclofen, a selective GABA(B) receptor agonist, on the induced Fos protein inc

57 The selective GABAB receptor agonist R-baclofen previously reversed so

58 The GABAB receptor agonist (R)-baclofen (10 microM) reduced

59 GABA(B) receptor agonists reduce receptor phosphorylatio

60 GABA(A) and GABA(B) receptor agonists stimulate feeding following mi

61 odification generates a potent and selective GABA(B) receptor agonist that inhibits Ca(v)2.2 channels

62 e prevention, we examined whether baclofen-a GABAB receptor agonist that reduces mesolimbic dopamine

63 as attenuated in the presence of GABA(A) and GABA(B) receptor agonists, the VMR was only consistently

64 Inhibition of calcium currents by GABAB receptor agonists was accompanied by an apparent c

65 rminals can be readily modulated, opioid and GABA(B) receptor agonists were applied.

66 of GHB was mimicked by baclofen, a selective GABAB receptor agonist, whereas the high affinity GHB re