ライフサイエンスコーパス: GDI

1 GDI vehicle PN EFs were found to increase by up to 240%

2 guanine nucleotide dissociation inhibitor-1 (GDI).

3 The fleet included 15 GDI vehicles, including 8 GDIs certified to the most-str

4 I endophthalmitis were identified among 4073 GDIs performed at the 2 institutions with active follow-

5 , we compare emissions of a flex-fuel Euro-5 GDI vehicle operated with gasoline (E0) and two ethanol/

6 fleet included 15 GDI vehicles, including 8 GDIs certified to the most-stringent emissions standard,

7 strate that eIF2B has a second activity as a GDI displacement factor (GDF) that can recruit eIF2 from

8 ing cells; Rac isoforms partially exist as a GDI-free pool at the membrane of resting cells, whereas

9 This study investigates the presence of a GDI for transducin in photoreceptor cells.

10 Expression of a GDI-1 mutant form (C-GDI) containing the C terminus (aa

11 ich led us to propose that there might be a 'GDI-displacement factor' to catalyse dissociation of Rab

12 promotes GTP hydrolysis by Ypt7p, and added GDI captures Ypt7p in its GDP-bound state during nucleot

13 Phacoemulsification after GDI surgery resulted in a transient reduction in IOP at

14 ha and Rho-GDIgamma, thereby eliminating all GDI activity in the brain, would produce an observable p

15 re emitted mostly during cold-start from all GDI and PFI vehicles.

16 lectomies (76.7% in 2008, 83.1% in 2016) and GDI procedures (77.7% in 2008, 80.6% in 2016).

17 motifs strongly potentiate their binding and GDI activity toward G alpha i1 even though the amino aci

18 GDP/GTP status is regulated by eIF5 (GAP and GDI functions) and eIF2B (GEF and GDF activities), while

19 onella pneumophila could act as both GEF and GDI-displacement factor (GDF) for Rab1.

20 ked complexes contain Rab escort protein and GDI-1.

21 Although REP and GDI share common Rab-binding properties, GDI cannot assi

22 e able to partially function as both REP and GDI.

23 organic compounds emissions between PFI and GDIs, including benzene, toluene, ethylbenzene, and xyle

24 s-phase pollutant emissions between PFIs and GDIs.

25 The percentage for trabeculectomy and GDIs decreased from 92.3% to 21.2%.

26 ose that the conserved Yip proteins serve as GDI-displacement factors for the targeting of Rab GTPase

27 cal to the ability of GPR-proteins to act as GDIs.

28 rates that then become trapped there because GDI cannot retrieve them.

29 Selective beta8 stimulation enhanced beta8-GDI interaction as well as Rac1 (but not RhoA) activatio

30 ediated cycling and help distinguish between GDI-dependent and -independent mechanisms, including ves

31 ree investigation of the interaction between GDI and Rab GTPases in a membrane environment.

32 The average interval between GDI surgery and phacoemulsification was 9.4 +/- 6.7 mont

33 The late endosomal, prenyl Rab9 binds GDI with very high affinity, which led us to propose tha

34 lization and to counteract the extraction by GDI.

35 ction of Rab GTPases from model membranes by GDI.

36 Expression of a GDI-1 mutant form (C-GDI) containing the C terminus (aa 69 to 204) also preve

37 cial users from lab.rockefeller.edu/casanova/GDI.

38 cytosis via the interaction between the Cav1 GDI region and Cdc42.

39 data suggest that Cav-1 functions as a Cdc42 GDI in beta-cells, maintaining Cdc42 in an inactive stat

40 suggested a novel role for Cav-1 as a Cdc42 GDI in beta-cells.

41 SULEV certified GDIs have a factor of 2 lower PM mass emissions than GDI

42 stability and sensitivity of the GC/CNT-CHIT-GDI-GDH biosensor allowed for the interference-free dete

43 sitivity (42 mA M(-1) cm(-2)) of the Pt/CHIT-GDI-AY9-GOx biosensor toward glucose.

44 e of platinum electrodes to form robust CHIT-GDI-AY9-GOx films for glucose biosensing.

45 ucose oxidase (GOx), was mixed with the CHIT-GDI-AY9 solution and cast on the surface of platinum ele

46 We compared GDI with the leading gene-level approaches, genic intole

47 ed its affinity for G alpha i1 and conferred GDI activity similar to that of AGS3-C itself.

48 Mutation of the conserved GDI motif creates a dominant-negative form of Sestrin th

49 chia coli (E. coli) crude extract containing GDI, suggest that this analogue will be an effective and

50 D4-GDI could prove to be a potential new target for therape

51 D4-GDI is a Rho GDP dissociation inhibitor that is widely e

52 anchorage-independent culture conditions, D4-GDI-depleted cells undergo rapid apoptosis (anoikis), wh

53 The Rho GDP dissociation inhibitor D4-GDI is overexpressed in some human breast cancer cell li

54 The cells lacking D4-GDI grown on Matrigel revert to a normal breast epitheli

55 Here, we show that silencing of D4-GDI by RNA interference abrogates tumor growth and lung

56 Knockdown of D4-GDI expression in MDA-MB-231 cells by RNA interference b

57 Reintroduction of D4-GDI fully restored both beta1-integrin expression and ce

58 Knockdown of D4-GDI in BT549 cells results in a similar effect.

59 activities and the spontaneous anoikis of D4-GDI knockdown cells.

60 Silencing of D4-GDI results in constitutive Rac1 activation and transloc

61 Silencing D4-GDI expression inhibits beta1-integrin expression and ce

62 We also found that D4-GDI associates with Rac1 and Rac3 in breast cancer cells

63 Here, we found that D4-GDI is expressed in a panel of breast cancer cell lines,

64 These results show that D4-GDI modulates breast cancer cell invasive activities.

65 These results suggest that D4-GDI regulates cell function by interacting primarily wit

66 ysis by mechanisms distinct from its defined GDI activity.

67 is the first example of a calcium-dependent GDI for heterotrimeric G proteins.

68 l Yellow 9 (AY9), using glutaric dialdehyde (GDI) as a molecular tether.

69 ing the system with the glutaric dialdehyde (GDI)-modified CHIT.

70 he CNT-CHIT films using glutaric dialdehyde (GDI).

71 pecialized proteins are required to displace GDI from Rab GTPases before Rab activation by guanosine

72 Therefore, the effective GDI displacement that is observed is caused by inhibitio

73 lacing PFI vehicles with more fuel efficient GDI vehicles remain uncertain.

74 etics of eIF2 release from the eIF2*GDP/eIF5 GDI complex and determine the effect of eIF2B on this re

75 that can recruit eIF2 from the eIF2*GDP/eIF5 GDI complex prior to GEF action.

76 s provide support for the importance of eIF5 GDI activity in vivo and demonstrate that eIF2beta acts

77 ssor mutation in eIF2beta that prevents eIF5 GDI and alters cellular responses to reduced eIF2B activ

78 how that the eIF2beta mutation prevents eIF5 GDI stabilizing nucleotide binding to eIF2, thereby alte

79 distinct from its RGS domain and established GDI activity.

80 RGS14 exerts GDI activity on Galphai1, but not Galphao.

81 eing prerequisites to constitute a bona fide GDI displacement factor.

82 s of Rabs can also modulate the affinity for GDI and thus cause effective displacement of GDI from Ra

83 rformed on the basis of diagnostic codes for GDI and endophthalmitis.

84 containing only the residues responsible for GDI activity), with Ric-8A:Galpha(il) and that of Ric-8A

85 g is an appealing manufacturing platform for GDIs, as it allows for incorporation of biocompatible po

86 /3 glucosamine units of chitosan and 25 free GDI tethers/1 molecule of GOx.

87 In this study, BC emissions from GDI and PFI vehicles were compiled and BC emissions scen

88 t for a small set, how the PM emissions from GDI vehicles change over their lifetime.

89 r findings indicate that SOA production from GDI vehicles will be reduced with the application of cat

90 omplexes and to enable transfer of Rabs from GDI onto membranes.

91 infection to effectively displace Rabs from GDI.

92 Rab1 released from GDI was inserted into liposomal membranes and was used a

93 easured 14.5% decrease in CO2 emissions from GDIs was much greater than the potential climate forcing

94 notoxic emissions on this specific flex-fuel GDI vehicle; however, other GDI vehicle types should be

95 ctron conductive films of such CHIT-NAD+-GDH-GDI-CHIT macrocomplexes (MC) were prepared on glassy car

96 Because the Rab:GDP:GDI complex is of high affinity, the question arises of

97 ifications may compensate for altered GTPase-GDI balance in disease scenarios.

98 rsinia depends strongly upon mimicry of host GDI proteins by YpkA.

99 of high affinity, the question arises of how GDI can be displaced efficiently from Rab protein in ord

100 However, GDI engines emit higher levels of black carbon (BC) aero

101 However, GDIs had, on average, a factor of 2 higher particulate m

102 terminal GoLoco region exhibiting G alpha(i) GDI activity.

103 /=18 mmHg in whom glaucoma drainage implant (GDI) surgery was planned were randomized to implantation

104 beculectomy) or a glaucoma drainage implant (GDI), but surgeries lose efficacy overtime, and the five

105 rabeculectomy and glaucoma drainage implant [GDI] procedure) and microinvasive glaucoma surgery (MIGS

106 trabeculectomy, glaucoma drainage implants (GDIs), and select minimally invasive glaucoma surgeries

107 th ratios for patients experiencing improved GDI QoL scores was 1.31 versus 1.56 for those without Qo

108 ded to understand BC formation mechanisms in GDI engines to ensure that the climate impacts of this e

109 Corticosterone also triggers an increased GDI phosphorylation at Ser-213 by the serum- and glucoco

110 ing a potential climate impact for increased GDI vehicle production.

111 this end, we derived the gene damage index (GDI): a genome-wide, gene-level metric of the mutational

112 ension (r = 0.83), and Gait Deviation Index (GDI), a comprehensive metric of gait impairment (r = 0.7

113 sessment Scale (MSAS)-Global Distress Index (GDI) and Functional Assessment of Cancer Therapy-Breast

114 rine chloride abrogated the thrombin-induced GDI phosphorylation and Rho activation.

115 Inhibiting GDI-1 phosphorylation at S96 is a potential therapeutic

116 Finally, eIF5 GDP dissociation inhibition (GDI) activity can antagonize eIF2 reactivation by compet

117 e guanine nucleotide dissociation inhibitor (GDI) activity of a GoLoco motif near their carboxy-termi

118 t guanine nucleotide dissociation inhibitor (GDI) activity, inhibiting the rate of exchange of GDP fo

119 t guanine nucleotide dissociation inhibitor (GDI) by contacting key residues in the regulatory switch

120 cytoplasm by the GDP dissociation inhibitor (GDI) chaperone.

121 on1-Ccz1), a Rab-GDP dissociation inhibitor (GDI) complex (prenylated Ypt7-GDI), and a Rab effector c

122 P guanine nucleotide dissociation inhibitor (GDI) complexes with the GDP-bound form of Rho and inhibi

123 at acts as a guanine dissociation inhibitor (GDI) for G(i/o)(alpha) subunits.

124 t guanine nucleotide dissociation inhibitor (GDI) for Galpha(i1).

125 a guanine nucleotide dissociation inhibitor (GDI) for Galphas using the same motif that allows it to

126 a guanine nucleotide dissociation inhibitor (GDI) for Gialpha.

127 rotein (GAP) and GDP dissociation inhibitor (GDI) functions, and eIF2B is the guanine nucleotide exch

128 eracted with Rho GDP dissociation inhibitor (GDI) in vivo, but Flag-TrkBT1DeltaC did not.

129 egulation by guanine dissociation inhibitor (GDI) proteins like LGN, a mammalian homolog of Drosophil

130 e guanine nucleotide dissociation inhibitor (GDI) Rdi1 recycles Cdc42 through the cytoplasm.

131 The GDP dissociation inhibitor (GDI) solubilizes prenylated Rab GTPases from and shuttle

132 with the protein GDP dissociation inhibitor (GDI) that binds to prenylated inactive (GDP-bound) Rab p

133 a guanine nucleotide dissociation inhibitor (GDI) that contains four G protein regulatory (GPR) or Go

134 a guanine nucleotide dissociation inhibitor (GDI) through its GoLoco motif.

135 a guanine nucleotide dissociation inhibitor (GDI), binds and stabilizes Galpha subunits in their GDP-

136 a guanine nucleotide dissociation inhibitor (GDI), mediates a fast recycling pathway, while actin pat

137 a guanine nucleotide dissociation inhibitor (GDI), which inhibits Cdc42 activation.

138 Guanosine nucleotide dissociation inhibitor (GDI), which regulates the cycle of Rab proteins between

139 e guanine-nucleotide dissociation inhibitor (GDI)-like domain of YopO cooperate for maximal anti-phag

140 r guanine nucleotide dissociation inhibitor (GDI)-like domains, and demonstrate that the presence of

141 h Guanine nucleotide Dissociation Inhibitor (GDI)-mediated membrane extraction and vesicle traffickin

142 n that acts as a GDP dissociation inhibitor (GDI).

143 ol by binding to GDP-dissociation inhibitor (GDI).

144 a guanine nucleotide dissociation inhibitor (GDI).

145 d guanine-nucleotide-dissociation-inhibitor (GDI).

146 ase cycle-Gdi1p (GDP-dissociation inhibitor [GDI]) or Gyp1p/Gyp7p (GTPase-activating protein)-this ki

147 both sensitive to the Rab-GTPase inhibitor, GDI, and to mutations in the vacuolar tether complex, HO

148 ncoding Rho guanine-dissociation inhibitors (GDI), known regulators of RhoGTPases/cytoskeleton.

149 Guanine nucleotide dissociation inhibitors (GDIs) bind and sequester GTPases in the cytosol, restric

150 guanine nucleotide dissociation inhibitors (GDIs) for G(alpha) subunits from the Gi family.

151 guanine nucleotide dissociation inhibitors (GDIs) for RAGA/B, and interact with GATOR2 with unknown

152 guanine nucleotide dissociation inhibitors (GDIs) for RagA/B.

153 uanidine nucleotide dissociation inhibitors (GDIs) of the Rho GTPases.

154 guanine nucleotide dissociation inhibitors (GDIs), form a complex with the GDP-bound form of the Rho

155 guanine nucleotide dissociation inhibitors (GDIs), GTPase-activating proteins (GAPs), or the chapero

156 e diphosphate (GDP) dissociation inhibitors (GDIs), such as activators of G protein signaling (AGS)-1

157 guanine nucleotide dissociation inhibitors (GDIs), which suggested a novel role for Cav-1 as a Cdc42

158 guanine nucleotide dissociation inhibitors (GDIs).

159 guanine-nucleotide dissociation inhibitors (GDIs).

160 s including Rab GDP dissociation inhibitors (GDIs).

161 guanine nucleotide dissociation inhibitors (GDIs).

162 ) engine exhaust, gasoline direct injection (GDI) engine exhaust has higher emissions of black carbon

163 uty vehicles with gasoline direct injection (GDI) engines equipped with and without catalyzed gasolin

164 Gasoline direct injection (GDI) is a new engine technology intended to improve fuel

165 enger vehicle and gasoline direct injection (GDI) vehicle were tested on a constant velocity driving

166 s from light-duty gasoline direct injection (GDI) vehicles (2013 Ford Focus) in an urban near-road en

167 from two pairs of gasoline direct injection (GDI) vehicles and port fuel injection (PFI) vehicles ove

168 e market share of gasoline direct injection (GDI) vehicles has increased significantly over the past

169 oline and also in gasoline direct injection (GDI) vehicles, which are quickly replacing traditional p

170 vehicle, and six gasoline direct injection (GDI) vehicles.

171 les equipped with gasoline direct-injection (GDI) engines.

172 from a light-duty gasoline-direct-injection (GDI) vehicle, over the FTP-75 and US06 transient drive c

173 r (GPR) domains that are responsible for its GDI function.

174 ndothelial cells transduced with full-length GDI-1.

175 tor 2 (RhoGDI2; also known as ARHGDIB and Ly-GDI) is associated with metastatic disease in patients w

176 The selected peptides also maintain GDI activity for G(i)(alpha)(1), inhibiting both the exc

177 ed between the Baerveldt 250 mm2 and 350 mm2 GDIs, respectively.

178 icant improvement in QoL as assessed by MSAS-GDI (P =.004) and FACT-B (P =.028).

179 Phosphodefective mutant GDI-1 also suppressed myosin light chain phosphorylation

180 Thirty cases (0.7%) of GDI endophthalmitis were identified among 4073 GDIs perf

181 protein AnkX, interferes with the ability of GDI to extract Rab35 from the membrane.

182 stitution rescued the inhibitory activity of GDI-1 toward RhoA but did not alter the thrombin-induced

183 ased engine power are reported advantages of GDI vehicles.

184 reveals that the lower apparent affinity of GDI for RacGTP compared to RacGDP can be fully explained

185 us of GDI-1 at Ser96 reduced the affinity of GDI-1 for RhoA and thereby enabled RhoA activation.

186 the GTPase and hence can inhibit binding of GDI to Rab:GDP complexes.

187 This analysis can reveal details of GDI-mediated cycling and help distinguish between GDI-de

188 GDI and thus cause effective displacement of GDI from Rab:GDI complexes.

189 associated with the enhanced fuel economy of GDI vehicles would yield a globally uniform negative rad

190 f GDI at Ser-213, increases the formation of GDI-Rab4 complex, facilitating the functional cycle of R

191 developed to evaluate the climate impact of GDI vehicles using global warming potential (GWP) and gl

192 The kinetics of GDI activity, however, are different for the selected pe

193 We also show that the mechanism of GDI activity of sNUCB1 is unique and does not arise from

194 13-acetate induced rapid phosphorylation of GDI and the activation of Rho-A in human umbilical venul

195 t corticosterone, via SGK phosphorylation of GDI at Ser-213, increases the formation of GDI-Rab4 comp

196 KC-epsilon induced marked phosphorylation of GDI in vitro.

197 of the phosphorylation of the C terminus of GDI-1 at S96 in selectively activating RhoA.

198 ediated phosphorylation of the C terminus of GDI-1 at Ser96 reduced the affinity of GDI-1 for RhoA an

199 ant mechanism by which the Sestrin family of GDIs regulates the nutrient-sensing Rag GTPases to contr

200 ty of GPR-proteins is different from that of GDIs for monomeric GTPases and from the GDI-like activit

201 costerone are altered by mutating Ser-213 on GDI.

202 differences in the effects of cold-start on GDIs and PFIs.

203 finities between GTPases and membrane and/or GDI on the amount of membrane bound GTPase.

204 f nucleotide dissociation inhibitors (NDI or GDI) for regulatory GTPases.

205 ecific flex-fuel GDI vehicle; however, other GDI vehicle types should be analyzed.

206 n regulatory(GPR) sequence, a 28-mer peptide GDI derived from the GoLoco (Galpha(i/0)-Loco interactio

207 this is the first example for a prokaryotic GDI, targeting a bacterial G protein-coupled membrane pr

208 and GDI share common Rab-binding properties, GDI cannot assist in Rab prenylation and REP cannot retr

209 We show that GEFs, but none of the proposed GDI displacement factors, are essential for the correct

210 a) subunits and the mechanism of GPR-protein GDI activity.

211 These results, obtained using purified GDI as well as Escherichia coli (E. coli) crude extract

212 ment factor' to catalyse dissociation of Rab-GDI complexes and to enable transfer of Rabs from GDI on

213 Prenyl Rab-GDI complexes contain all of the information necessary t

214 Yip1p function requires Rab-GDI and Rab proteins, and several mutations that abrogat

215 cause effective displacement of GDI from Rab:GDI complexes.

216 occur after spontaneous dissociation of Rab:GDI complexes within their natural equilibrium.

217 s caused by inhibition of reformation of Rab:GDI complexes.

218 Rendering GDI-1 phosphodefective with a Ser96 --> Ala substitution

219 nal and evolutionary organization of the REP/GDI superfamily.

220 The striking selectivity observed for RGS14 GDI activity in vitro points to Galphai1 and Galphai3 as

221 Galphai2 be rendered sensitive to RGS14 GDI activity by replacement of residues within the alpha

222 her all three isoforms were subject to RGS14 GDI activity.

223 The overexpression of bovine Rho GDI alpha disrupted membrane translocation of Rho, Rac a

224 e regulation of receptor coactivators by Rho GDI.

225 , which binds CBP/p300, is necessary for Rho GDI to modulate GRIP1 activity.

226 Indeed, Rho GDI cooperates with GRIP1 to increase ER ligand-independ

227 d bovine Rho GDP dissociation inhibitor (Rho GDI alpha), which serves as a negative regulator of Rho,

228 hibitor alpha (RhoGDIalpha), a member of Rho GDI family that is involved in cytoskeletal reorganizati

229 CBP activity, we find that the effect of Rho GDI on ER transactivation is CBP/p300-dependent.

230 We now demonstrate that Rho GDI-dependent increase in ER transactivation is dependen

231 At E14.5, the size of the Rho GDI alpha Tg lenses was larger compared to wild type (WT

232 the ability of CBP/p300 to transduce the Rho GDI signal to ER occurs through both GRIP1-dependent and

233 ed the expression of the gene encoding a Rho-GDI homolog in the human fungal pathogen Cryptococcus ne

234 isrupts the interaction between RhoA and Rho-GDI (guanine nucleotide dissociation inhibitor) and prom

235 iation inhibitor (Rho-GDI) from an ezrin/Rho-GDI complex.

236 ation of Rho GDP dissociation inhibitor (Rho-GDI) from an ezrin/Rho-GDI complex.

237 ssion of Rho GDP dissociation inhibitor (Rho-GDI), inhibited the strain-induced activation of NF-kapp

238 Rho-GDP dissociation inhibitors (Rho-GDI) are repressors of Rho-type monomeric GTPases that c

239 In addition, reduction of Rho-GDI by small interfering RNA in pRb-transfected cells pr

240 The release of Rho-GDI results in increased interaction with Rac1 GTPase an

241 dation resistant mutant IkappaBalpha) or Rho-GDI blocked the strain-induced proliferation of C2C12 ce

242 3 and another known ERM binding protein, Rho-GDI.

243 elies on SPIKE1 Rho-GEF, SUPERCENTIPEDE1 Rho-GDI, and ACTIN7 (ACT7) function and to a lesser extent o

244 ted flat cell formation, suggesting that Rho-GDI plays an important role in contributing to cellular

245 ed mechanism of RhoA activation from the Rho-GDI-1 complex and its role in mediating increased endoth

246 Two Rho-GDI isoforms are expressed in the brain, Rho-GDIgamma an

247 Rho-GDIs are a family of Rho GDP-dissociation inhibitors tha

248 f GIV-Galphas complexes, and activates GIV's GDI function.

249 expressing the phospho-mimicking mutant S96D-GDI-1 protein induced RhoA activity and increased endoth

250 ted impact on BC emissions from the selected GDI and PFI vehicles during hot-starts.

251 (GPF) reduced BC emissions from the selected GDI vehicle by 73-88% at various ambient temperatures ov

252 complex that functions as a RhoA-selective, GDI dissociation factor.

253 gnaling mechanism by which TrkBT1 sequesters GDI and activates RhoA signaling.

254 The stock-GDI vehicle emits graphitized fractal-like aggregates ov

255 e-matter emission, the results for the stock-GDI vehicle, that is, the vehicle in its original config

256 t 20% larger than those emitted by the stock-GDI vehicle.

257 Eyes with infection source other than GDI were excluded.

258 e a factor of 2 lower PM mass emissions than GDIs certified as ultralow-emission vehicles (3.0 +/- 1.

259 e, and de novo excess, and demonstrated that GDI performed best for the detection of false positives

260 -based analysis, it was also determined that GDI vehicles are climate beneficial within <1-20 years;

261 uated total reflection experiments show that GDI genuinely accelerates the intrinsic Rab membrane dis

262 The GDI BC emissions spanned 2 orders of magnitude and varie

263 The GDI server, data, and software are freely available to n

264 cell culture experiments, the kinase and the GDI domains of YpkA act synergistically to promote cytos

265 Other than for NOx and CO, the GDI engine had elevated emissions compared to the Toront

266 reas a cell-permeable peptide containing the GDI motif inhibits mTORC1 signaling.

267 cking phosphorylation on Thr494 enhanced the GDI activity of RGS14 toward Galpha(i) nearly 3-fold, wi

268 BC concentrations were higher for the GDI vehicles than the PFI and hybrid vehicles, suggestin

269 10 was found to reduce BC emissions from the GDI vehicle by 15% at standard temperature and by 75% at

270 , the GPF reduced BC mass emissions from the GDI vehicle by 59-80% at various temperatures.

271 ity can coordinate Rab1 recruitment from the GDI-bound pool.

272 t of GDIs for monomeric GTPases and from the GDI-like activity of G(betagamma) subunits.

273 e of myristoylated ciliary proteins from the GDI-like solubilizing factor UNC119a/b.

274 We identified the GDI-1-regulated mechanism of RhoA activation from the Rh

275 Our data suggest that a mechanism of the GDI activity of GPR-proteins is different from that of G

276 RhoGDI2 is a member of the GDI family that acts as a metastasis suppressor in a var

277 The size of the GDI may not be associated with surgical outcomes.

278 over the level accomplished by action of the GDI-like domain alone.

279 ssible effects of PKA phosphorylation on the GDI activity of RGS14.

280 s were observed on the PFI vehicles than the GDI vehicles.

281 We found that the GDI was correlated with selective evolutionary pressure,

282 ssion of Cav2, or a Cav1 mutant in which the GDI region was altered to the corresponding sequence in

283 uggest that GAP activity cooperates with the GDI to counteract the dissipative effect of a previously

284 Thereby, GDI is revealed to actively extract monogeranylgeranylat

285 This GDI activity is isolated to a region of the protein dist

286 ated Rabs also occur in the cytosol bound to GDI (guanine nucleotide dissociation inhibitor), which b

287 y, is poorly prenylated, and is not bound to GDI in the cytosol; nevertheless, Rab29 only activates L

288 sociate complexes of endosomal Rabs bound to GDI, and to deliver them onto membranes.

289 fects of shifting the U.S. fleet from PFI to GDI technology.

290 Thus, switching from PFI to GDI vehicles will likely lead to a reduction in net glob

291 iles modified to reflect a shift from PFI to GDI, we calculated the change in aerosol (mostly BC) con

292 from 855 to 1599 due to shifting from PFI to GDI.

293 ts particle mass and number emissions of two GDI vehicles as a function of mileage up to 150K miles.

294 ve cycle, the BC mass emissions from the two GDI vehicles at 0 degrees F (-18 degrees C) varied from

295 Moreover, 5MP1 is not a GEF but a weak GDI for yeast eIF2.

296 y improvements ranging from 0.14 to 14% with GDI vehicles are required to offset BC-induced warming.

297 -like nanoparticles are also associated with GDI technology with yet unknown health impacts.

298 ge the K(D) for the interaction of Rac1 with GDI, and similar to that previously observed for Cdc42,

299 a Y. pseudotuberculosis mutant lacking YpkA GDI activity shows attenuated virulence in a mouse infec

300 ion inhibitor (GDI) complex (prenylated Ypt7-GDI), and a Rab effector complex (HOPS).