ライフサイエンスコーパス: GDP dissociation inhibitor

1 /SLY1-20 membranes remained sensitive to Rab GDP dissociation inhibitor.

2 either on membranes or in cytosol, bound to GDP dissociation inhibitor.

3 vating protein and ARF domains, may act as a GDP dissociation inhibitor.

4 of cultured cells is not associated with Rab GDP dissociation inhibitors.

5 A-binding protein (FUS) with rs1538664A, Rho GDP dissociation inhibitor 1 (ARHDGIA) with rs479200T an

6 horylation of Rab1 disrupts interaction with GDP dissociation inhibitor 1 (GDI1), but not guanine exc

7 beta8 integrin coimmunoprecipitates with Rho-GDP dissociation inhibitor 1 (RhoGDI1), an intracellular

8 calization and phosphorylation status of Rho GDP dissociation inhibitor 1 (RhoGDI1).

9 f the first small-molecule ligand of the RHO GDP-dissociation inhibitor 1 (RHOGDI1), termed Rhonin.

10 Rho GDP dissociation inhibitor 2 (RhoGDI2) has been identifi

11 A reduction in Rho GDP Dissociation Inhibitor 2 (RhoGDI2) protein has been

12 t inhibitor of Rho proteins known as the Rho-GDP dissociation inhibitor 2 (RhoGDI2).

13 BB4b, vimentin), only antibodies against Rho GDP-dissociation inhibitor 2 (ARHGDIB) (adjusted MFI [aM

14 cyte plasma membrane-associated protein, Rho GDP-dissociation inhibitor 2 [ARHGDIB], Rho guanine nucl

15 and Rho1-GDP in vitro and that Msb3 and Rho GDP dissociation inhibitor act independently but opposit

16 acts through its two GoLoco motifs to exert GDP dissociation inhibitor activity over Galpha(i) subun

17 nding domains, and a GoLoco motif, which has GDP dissociation inhibitor activity.

18 in cell survival and proliferation, and Rho GDP dissociation inhibitor alpha (RhoGDIalpha), a member

19 Previous studies revealed that Rho GDP-dissociation inhibitor alpha (RhoGDIalpha) is involv

20 y-based probe revealed Sec23 homologue A and GDP-dissociation inhibitor alpha as potential targets im

21 ory subunit/DJ-1 PARK7) and RhoGDIalpha (Rho GDP-dissociation inhibitor alpha).

22 ors of Gbetagamma signaling pathways, act as GDP dissociation inhibitors and negatively regulate the

23 pase substrates poly(ADP-ribose) polymerase, GDP dissociation inhibitor, and PKCdelta was observed wh

24 gration inhibitors Nme1, Nme2, and Nme3, the GDP dissociation inhibitor Arhgdib, and the metalloprote

25 s, including beta-lactate dehydrogenase, Rho GDP dissociation inhibitor beta, ATP synthase, elongatio

26 (TORC1), by its direct association with Rab GDP dissociation inhibitor beta, which likely regulates

27 We demonstrate that modification of Rab GDP-Dissociation Inhibitor Beta (GDI2) by ISG15 (ISGylat

28 TP-binding proteins of the rab family by rab GDP dissociation inhibitor completely abolishes formatio

29 needs further investigation to clarify how a GDP-dissociation inhibitor could potently inhibit these

30 The Rho GDP dissociation inhibitor D4-GDI is overexpressed in so

31 inhibition of Pak1 kinase activity and Rac1-GDP-dissociation inhibitor disassociation, and inhibitio

32 cytosol, and this effect was blocked by the GDP dissociation inhibitor for Rho (Rho-GDI).

33 ressing Rho GDIalpha, an endogenous specific GDP dissociation inhibitor for Rho family proteins, usin

34 ieved by expressing Rho GDIalpha, a specific GDP dissociation inhibitor for Rho family proteins, usin

35 that D4-GDI, an abundant hematopoietic cell GDP dissociation inhibitor for the Ras-related Rho famil

36 ates poly(ADP ribose) polymerase and D4-GDI (GDP dissociation inhibitor for the rho family), as well

37 roteins as nucleotide exchange factors or as GDP dissociation inhibitors for Galpha have been propose

38 results suggest that GPR proteins are potent GDP dissociation inhibitors for Gialpha-like Galpha subu

39 orm are kept soluble in the cytoplasm by the GDP dissociation inhibitor (GDI) chaperone.

40 tide exchange factor (GEF, Mon1-Ccz1), a Rab-GDP dissociation inhibitor (GDI) complex (prenylated Ypt

41 s both GTPase-accelerating protein (GAP) and GDP dissociation inhibitor (GDI) functions, and eIF2B is

42 TrkBT1 interacted with Rho GDP dissociation inhibitor (GDI) in vivo, but Flag-TrkBT

43 Rab-GDP dissociation inhibitor (GDI) is an important modulat

44 nction, was perturbed by modest increases in GDP dissociation inhibitor (GDI) levels.

45 The GDP dissociation inhibitor (GDI) solubilizes prenylated

46 is mediated by interaction with the protein GDP dissociation inhibitor (GDI) that binds to prenylate

47 Membrane-bound GDP-Rabs interact with GDP dissociation inhibitor (GDI), resulting in the disso

48 Rush also directly binds to Rab GDP dissociation inhibitor (Gdi), which is involved in t

49 red for Rab localization and function is Rab GDP dissociation inhibitor (GDI), which is proposed to r

50 efore a bi-functional protein that acts as a GDP dissociation inhibitor (GDI).

51 rab4 complexed with its cytosolic chaperone, GDP dissociation inhibitor (GDI).

52 ion and GTP hydrolysis on Cdc42Hs by the Rho GDP-dissociation inhibitor (GDI) is extremely sensitive

53 structure of the bovine alpha-isoform of Rab GDP-dissociation inhibitor (GDI), which functions in ves

54 are maintained in the cytosol by binding to GDP-dissociation inhibitor (GDI).

55 rmations bound to a cytosolic protein termed GDP-dissociation inhibitor (GDI).

56 or their function appears to be regulated by GDP-dissociation inhibitors (GDI), three of which have b

57 The GDP-dissociation-inhibitor (GDI) for Rho-like GTP-bindin

58 ns that regulate the Rab GTPase cycle-Gdi1p (GDP-dissociation inhibitor [GDI]) or Gyp1p/Gyp7p (GTPase

59 The GDP dissociation inhibitors (GDIs) represent an importan

60 ffinity to regulatory proteins including Rab GDP dissociation inhibitors (GDIs).

61 Guanosine diphosphate (GDP) dissociation inhibitors (GDIs), such as activators

62 Guanosine diphosphate (GDP)-dissociation inhibitors (GDIs) belong to one of thr

63 The Rho GDP-dissociation inhibitors (GDIs) negatively regulate R

64 GDP-dissociation inhibitors (GDIs) play a primary role i

65 GDP-dissociation inhibitors (GDIs) play a primary role i

66 lls, fails to form detectable complexes with GDP-dissociation inhibitors (GDIs).

67 -synuclein on synaptic vesicles and that the GDP dissociation inhibitor.Hsp90 complex that controls R

68 also demonstrated modulatory roles for Rac1/GDP dissociation inhibitor in glucose-stimulated insulin

69 Purified GDP-dissociation inhibitor inhibited homotypic lysosome

70 G protein binding region of Cavce possesses "GDP dissociation inhibitor-like activity" with the same

71 Here, we report that FeoB harbors a novel GDP dissociation inhibitor-like domain that specifically

72 CARD9 associated with the GDP-dissociation inhibitor LyGDI in phagosomes after bac

73 Ras from the PM, in a process reminiscent of GDP dissociation inhibitor-mediated membrane recycling o

74 sm that does not depend on GTP hydrolysis or GDP dissociation inhibitor-mediated recycling.

75 ficient Rab3a mutant, by a dominant-negative GDP dissociation inhibitor mutant unable to recycle Rab3

76 f Cdc42-guanosine diphosphate (GDP) from Rho GDP dissociation inhibitor or for the membrane recruitme

77 genous Cdc42 from Golgi membranes by the Rho-GDP dissociation inhibitor protein fails to solubilize I

78 s morphogenesis, we overexpressed bovine Rho GDP dissociation inhibitor (Rho GDI alpha), which serves

79 kinase 5 and consequent dissociation of Rho GDP dissociation inhibitor (Rho-GDI) from an ezrin/Rho-G

80 o GTPases activity, by overexpression of Rho GDP dissociation inhibitor (Rho-GDI), inhibited the stra

81 Rho-GDP dissociation inhibitors (Rho-GDI) are repressors of

82 ous Rac1 and two known binding partners, Rho GDP dissociation inhibitor (RhoGDI) and p21-activated ki

83 nts, we found that Rac1 dissociates from Rho GDP dissociation inhibitor (RhoGDI) and translocates to

84 The Rho GDP dissociation inhibitor (RhoGDI) can bind to small GT

85 We have investigated the effects of Rho GDP dissociation inhibitor (RhoGDI) on exocytosis induce

86 Rho GDP dissociation inhibitor (RhoGDI) plays an essential r

87 ned SCN1 and showed that SCN1 is a RhoGTPase GDP dissociation inhibitor (RhoGDI) that spatially restr

88 mechanisms underlying the ability of the Rho-GDP dissociation inhibitor (RhoGDI) to elicit the releas

89 XIAP depends on its interaction with the Rho GDP dissociation inhibitor (RhoGDI) via the XIAP RING do

90 ycling of the Rho GTPases is mediated by Rho GDP dissociation inhibitor (RhoGDI), which forms a stabl

91 ent in the interaction of Cdc42 with the Rho-GDP dissociation inhibitor (RhoGDI).

92 on of both RhoA and Rac1; an increase in Rho GDP-dissociation inhibitor (RhoGDI) binding in the absen

93 ecently shown that reduced expression of the GDP dissociation inhibitor, RhoGDI2, is associated with

94 by the transgenic overexpression of the Rho GDP dissociation inhibitor RhoGDIalpha.

95 volatile anesthetic, halothane, with the Rho GDP dissociation inhibitor (RhoGDIalpha), which binds th

96 uced into the cells was shown to bind to rab GDP dissociation inhibitor, suggesting that this pool of

97 D4-GDI is a Rho GDP dissociation inhibitor that is widely expressed in h

98 Rho-GDIs are a family of Rho GDP-dissociation inhibitors that are critical in modulat

99 to bind RhoA but coprecipitates RhoGDI (Rho GDP dissociation inhibitor), the primary RhoA repressor

100 b GTPases (by preincubation of vesicles with GDP dissociation inhibitor), together with cytosol immun

101 We then used immunodepleted cytosol and GDP dissociation inhibitor-treated vesicles to determine

102 itro extraction of rab4 (but not rab11) with GDP dissociation inhibitor was severely attenuated in NP

103 With the understanding of YM acting as a GDP-dissociation inhibitor, we propose that Ric-8A hinde

104 ed on Rab5a and phosphorylated EEA-1 and Rab GDP dissociation inhibitor, with the latter causing Rab5