ライフサイエンスコーパス: GDP

1 GDP binding to the apo conformation of EF-Tu is both ent

2 GDP polyribonucleotidyltransferase (PRNTase) is an uncon

3 At $8,000 GDP per capita, the adjusted probability of being obese

4 ian injecting duration (0.11 years per $1000 GDP increase, 95% CI 0.04-0.18; p=0.002), and older medi

5 Adding a GDP.P(i) intermediate did not improve the model.

6 with unconventional mRNA capping enzymes: a GDP:polyribonucleotidyltransferase (PRNT) and a dual-spe

7 We explored whether incorporating a GDP.P(i) state or the likely effects of conformational a

8 Product mass suggests formation of a GDP(S) adduct along with a second thiophosphorylation, i

9 Moreover, expression of a GDP-bound Rab5 mutant (Rab5/S34N) or shRNA-mediated knoc

10 il displays preference for a GTP-type over a GDP-type microtubule lattice and contributes to the inte

11 imilar to Streptomyces hygroscopicus VldE, a GDP-valienol-dependent pseudoglycosyltransferase enzyme.

12 identify an unforeseen principle by which a GDP-bound form of the conserved small G protein Rho GTPa

13 ical pathogen prevalence) and both absolute (GDP) and relative wealth (GINI).

14 nerate GDP-Arap, while synthesizing abundant GDP-fucose.

15 imate-driven decreases in economic activity (GDP) may in turn decrease human energy use and thus foss

16 lopmental syndrome, likely caused by altered GDP/GTP binding that inactivate the protein and induce G

17 p = 0.003; women: r = -0.369, p < 0.001) and GDP per capita (men: r = -0.164, p = 0.036; women: r = -

18 e that tautomerizes to form H(2)PO(4)(-) and GDP as the final products.

19 a transient complex between the beta2AR and GDP-bound Gs protein (beta2AR-Gs(GDP)) that may represen

20 oups, geographic regions, age, education and GDP levels, and increasing trend was observed over the 5

21 is mainly dimeric in the nucleotide-free and GDP-bound states, while it forms monomers upon GTP bindi

22 A competition assay between GDP and GDP analogues in the GpppA formation and pRNA transfer a

23 ay enzymes GDP-mannose dehydratase (GMD) and GDP-fucose synthetase (GMER) were expressed ectopically;

24 ed by GDP-mannose 4,6-dehydratase (GMDS) and GDP-4-keto-6-deoxymannose 3,5-epimerase-4-reductase (FX

25 ms of the biochemical properties of GTP- and GDP-bound alphabeta-tubulin predict the concentration de

26 EF-Tu alternates between GTP- and GDP-bound conformations during its functional cycle, rep

27 kably, "cross"-dimerization between GTP- and GDP-bound KRAS molecules is unfavorable.

28 th distinct polarity factors in its GTP- and GDP-bound states.

29 hort segment of a closed MT in both GTP- and GDP-bound states.

30 they do not actively cycle between GTP- and GDP-bound states.

31 i.e., what is different between the GTP- and GDP-tubulin states that enables microtubule growth and s

32 s the energy difference between the GTP- and GDP-tubulin thermodynamic states.

33 that likely correspond to GTP, GDP.P(i), and GDP.

34 ypotension, altitude higher than >500 m, and GDP per capita were significantly associated with surviv

35 ested GDP-D-erythro-alpha-D-gluco-octose and GDP-D-alpha-D-lincosamide as key intermediates in the pa

36 actose 1-phosphate, glucose 1-phosphate, and GDP-glucose when grown on galactose.

37 ne nucleotide exchange factor (GEF) for ARL3-GDP.

38 capable of generating GDP-glucose as well as GDP-mannose.

39 A competition assay between GDP and GDP analogues in the GpppA formation and pRNA tr

40 capita, but we found no relationship between GDP per capita and CO(2) emissions rates.

41 Small GTPases alternatively bind GDP/GTP guanine nucleotides to gate signaling pathways t

42 bit subtle differences in their GTP-binding, GDP/GTP-exchange, and GTP-hydrolysis activities, but the

43 e presence of ML297 or the G-protein blocker GDP-beta-S, DA induced a further decrease in spike firin

44 We simulated these mutations in both GDP- and GTP-bound Cdc42.

45 responds to an increased occupancy for bound GDP, suggesting an induced-fit folding of the donor-bind

46 activation and is inactive either with bound GDP or without bound guanine nucleotide.

47 tizes the enzyme to allosteric inhibition by GDP/GTP.

48 s, requires sequential reactions mediated by GDP-mannose 4,6-dehydratase (GMDS) and GDP-4-keto-6-deox

49 nylyl imidodiphosphate and the next three by GDP, which is suggestive of sequential GTP hydrolysis.

50 generated, we characterized three candidate GDP-glucose pyrophosphorylases.

51 conclude that, in addition to the canonical GDP-GTP exchange-dependent mechanism, plant G proteins c

52 presence in neighbouring regions, per capita GDP and global prevalence.

53 are increased to 3.3-14.6% of the per capita GDP at retail market pharmaceutical prices.

54 population-weighted country-level per capita GDP distribution, yielding a ratio between the top and b

55 ica, amounting to 0.4-6.2% of the per capita GDP in these countries.

56 ies there is >90% likelihood that per capita GDP is lower today than if global warming had not occurr

57 We used per-capita GDP (PPP) and life expectancy from 61 countries in 2014-

58 he G-protein transducin (G(T)) by catalyzing GDP-GTP exchange on its alpha subunit (Galpha(T)).

59 complexes activate Rab GTPases by catalyzing GDP/GTP nucleotide exchange.

60 e only known enzyme responsible for cellular GDP production, making it essential for cellular viabili

61 about 89% to 96% of the variation of cities' GDP across three provinces in China.

62 erization, and 6-transamination that convert GDP-D-erythro-alpha-D-gluco-octose to GDP-D-alpha-D-linc

63 mployed by fucosyltransferases to coordinate GDP, features that define acceptor substrate preferences

64 However, distributing current GDP growth more equally across income groups as in the 1

65 states, only one of which (RagA/B*GTP-RagC/D*GDP) permits mTORC1 association.

66 eful in providing insight into inter-decadal GDP variability over this period.

67 ights into specific aspects of inter-decadal GDP variability, such as on the nature of the business c

68 only in the inactive guanosine diphosphate (GDP)-bound form of KRAS(G12C), sparing the wild-type pro

69 ference for GTP- over guanosine diphosphate (GDP)-bound MT lattice and competes with end-binding prot

70 De novo synthesis of guanosine diphosphate (GDP)-fucose, a substrate for fucosylglycans, requires se

71 ural disparity are age structure, education, GDP, health care services, air conditioners, and occupat

72 exchange factor that recycles inactive eIF2*GDP to active eIF2*GTP.

73 Following GTP hydrolysis, eIF2-GDP is recycled back to TC by its guanine nucleotide exc

74 he complex of eIF2B with its substrate, eIF2-GDP, reaction intermediates, apo-eIF2 and eIF2-GTP, and

75 IF5, thought to primarily function with eIF2-GDP and TC respectively.

76 tii mutant affected in theVTC2 gene encoding GDP-l-Gal phosphorylase, which catalyzes the first commi

77 fied proteins suggested that l-PGDS enhances GDP-GTP exchange on Rab4.

78 gene encoding the fucose biosynthetic enzyme GDP-d-mannose-4,6-dehydratase.

79 ssess an unconventional mRNA capping enzyme (GDP polyribonucleotidyltransferase, PRNTase) domain with

80 rst, the trypanosome de novo pathway enzymes GDP-mannose dehydratase (GMD) and GDP-fucose synthetase

81 SOS1 exchanges GDP by GTP, activating Ras.

82 After adjusting for GDP per capita, length of highways, female illiteracy, t

83 change kinetics but have a high affinity for GDP.

84 tomyces venezuelae has such a preference for GDP-glucose and can utilize ADP-glucose to some extent t

85 iness indicators and any outcome, apart from GDP (OR, 1.70 [95% CI 1.12-2.59], p = 0.01), HDI (OR, 1.

86 erm global decoupling of freight demand from GDP.

87 ments and miniring structures formed by FtsZ-GDP.

88 en the composition of oligomers of free FtsZ-GDP and free FtsZ-GTP formed in solution.

89 In the case of FtsZ-GDP, equilibrium binding does not appear to be saturable

90 head domain within the elongation factor G (GDP)-bound ribosome complex.

91 localization is regulated by binding Galphai-GDP, whereas RGS14 nuclear export is regulated by Export

92 Q variants disrupt RGS14 binding to Galphai1-GDP and XPO1, nucleocytoplasmic equilibrium, and capacit

93 MD-GMER line lacked the capacity to generate GDP-Arap, while synthesizing abundant GDP-fucose.

94 ophosphorylase that is capable of generating GDP-glucose as well as GDP-mannose.

95 rt to mitigation, reaching 15(17)% of global GDP in 2085(2070) for a 1990 start and 18(35)% in 2080(2

96 We find impacts of climate changes on global GDP-per-capita by the end of the century are temperature

97 Global EAD are small relative to global GDP (~0.02%).

98 otides, impacting the cellular pools of GMP, GDP and GTP.

99 inducing pathology due to loss of the Golgi GDP mannose transporter.

100 beta2AR and GDP-bound Gs protein (beta2AR-Gs(GDP)) that may represent an intermediate on the way to t

101 n the lattice that likely correspond to GTP, GDP.P(i), and GDP.

102 ong three nucleotide states of tubulin, GTP, GDP, and GMPCPP and is estimated to be ~ -11 k(B)T.

103 fecting the interaction of eIF2 with its GTP-GDP exchange factor eIF2B.

104 e proposed GAP role for ELMOD1, the ARF6 GTP/GDP ratio was significantly elevated in rda/rda utricles

105 t normally occur at the GTP-rich ends of GTP/GDP MTs and that may be compromised in neurodegeneration

106 phate from ATP to the oxygen of 3'-OH of GTP/GDP.

107 mutations that affect GTP hydrolysis or GTP/GDP exchange modified this localization.

108 ve been shown to recognize a stabilizing GTP/GDP-Pi cap at the tip of growing MTs, but information ab

109 e predicted that both variants alter the GTP/GDP binding pocket and show that they both have localiza

110 Decreasing the cytosolic GTP:GDP ratio increases the incorporation of Shs1 vs Cdc11,

111 sidues involved in stabilization of hepcidin-GDP complex.

112 0.65, 95% CI 0.10 to 1.20, p=0.021), higher GDP per capita purchasing power parity (beta coefficient

113 ntry level, in multivariable analysis higher GDP was associated with longer median injecting duration

114 lower rate of absolute poverty, with higher GDP and health-care spending per capita, a higher propor

115 risk behaviours, and relative to the highest GDP per capita tertile, the middle tertile was associate

116 ability and secular stagnation in historical GDP data.

117 odel substrate and to specifically hydrolyze GDP-Fuc.

118 AtPTPN and ZmPTPN release Pi by hydrolyzing GDP/GMP/dGMP/IMP/dIMP, and that AtPTPN positively regula

119 For hypertension, GDP and HDI were both positively associated with each ou

120 Even greater gains in GDP (PPP) were seen for Moscow, the Russian capital, rea

121 KRAS dimers in the active GTP- and inactive GDP-loaded states.

122 ular switches", alternating between inactive GDP-bound and active GTP-bound conformation.

123 s of signaling by switching between inactive GDP-bound and active GTP-bound forms.

124 on of RAS by converting it from its inactive GDP-bound state to its active GTP-bound state.

125 effects of both variants with known inactive GDP- and active GTP-bound RAB11B mutants, we modeled the

126 , which allow RAS to cycle from the inactive GDP-bound state to the active GTP-bound form.

127 ulations of active (GTP-bound) and inactive (GDP-bound) forms of wild-type and mutant K-Ras, with an

128 ycle between active, GTP-bound and inactive, GDP-bound states.

129 interacted preferentially with the inactive, GDP-locked Rab4S22N variant rather than with WT Rab4 or

130 To address the question of why Tau is GDP-tubulin-biased, we tested whether Tau might affect M

131 epublic of Kiribati, which earns much of its GDP by selling tuna fishing licenses to foreign nations.

132 g of a variety of effectors depending on its GDP/GTP-bound state.

133 sults suggest that conversion of ARF6 to its GDP-bound form is necessary for final stabilization of t

134 Based on the Kenyan GDP per capita of $1445, and in comparison to other vacc

135 Structural studies on N-acetylated KRAS-GDP lacking the iMet revealed the presence of Mg(2+) and

136 In the Mg(2+)-free KRAS-GDP structure, the flexible N-terminus causes conformati

137 ced upregulation of the succinate-CoA ligase GDP-forming beta subunit (SUCLG2), which regulates succi

138 Patients living in countries with lower GDP had greater disease activity and damage than those l

139 the G-protein RhoA complexed with MgF3(-) , GDP, and RhoGAP, which has the mutation Arg85'Ala.

140 imulating the conversion of MglA-GTP to MglA-GDP.

141 cts in the USA were correlated with national GDP.

142 Preferential binding to dominant negative (GDP-bound) versus wild-type or constitutively active (GT

143 due to breast cancer, from 0.05% to 0.08% of GDP.

144 er, in some countries EAD reach 0.5 to 1% of GDP annually, which is the same order of magnitude as na

145 ries assuming a WTP value of at least 50% of GDP per capita per DALY averted, and in 49 assuming a mi

146 an estimated $3.1 trillion in 2016 (17.9% of GDP; $9655 per person); 85.2% of that spending was inclu

147 Interestingly, the co-administration of GDP and ferrous sulphate (FeSO4) ameliorated the turpent

148 1), which is involved in the biosynthesis of GDP-l-fucose.

149 zed reactions resulting in the conversion of GDP-D-erythro-alpha-D-gluco-octose to GDP-D-alpha-D-linc

150 ure and dynamics of the catalytic domains of GDP-bound (inactive) and GTP-bound (active) Cdc42 in sol

151 help move us towards real-time estimates of GDP, which would equip policymakers with the information

152 d are primarily regulated by the exchange of GDP and GTP.

153 In animals and fungi, the exchange of GDP for GTP on Galpha controls G protein activation and

154 changer 1 (P-Rex1) catalyzes the exchange of GDP for GTP on Rac GTPases, thereby triggering changes i

155 Rho*) is the GPCR catalyzing the exchange of GDP for GTP on the heterotrimeric G protein transducin (

156 GEFs catalyze exchange of GDP for GTP; the GTP-bound, activated, Rab then recruits

157 sociable signaling pathways: the exchange of GDP to GTP by linked G-proteins and the recruitment of b

158 more, either the 2'- or 3'-hydroxyl group of GDP was found to be required for efficient pRNA transfer

159 analogues and identified chemical groups of GDP as essential for the substrate activity.

160 a lack of fucosylation consequent to loss of GDP-fucose synthesis contributes to colon carcinogenesis

161 re not reflected in conventional measures of GDP and productivity.

162 oxo group, N-1-hydrogen, or N-7-nitrogen, of GDP for the cap formation.

163 verage, the economic burden as percentage of GDP was larger in middle-income countries than in high-i

164 ment expenditure on health [as percentage of GDP], private, and out-of-pocket expenditure on health [

165 on produce the same biochemical phenotype of GDP-fucose deficiency.

166 ions of our UHC indicators with the share of GDP spent on health and the shares of health spending ch

167 Increasing the share of GDP spent on health is not sufficient to reduce catastro

168 itively with GDP per person and the share of GDP spent on health, and incidence correlated negatively

169 ons indicate that enthalpic stabilization of GDP binding compared to GTP binding originates in the ba

170 Here, we report a crystal structure of GDP-bound KRAS(V14I), a mutated KRAS variant associated

171 ch regions also observed in the structure of GDP-bound unprocessed KRAS with the iMet.

172 , and N-Ras, and can identify GEFs by use of GDP-bound forms.

173 tive to their predicted performance based on GDP per capita, whereas countries in sub-Saharan Africa

174 l care cascade steps than predicted based on GDP per capita.

175 Interestingly, structural studies on GDP- and GMPPNP-bound KRAS lacking the iMet and N-acetyl

176 The binding of GTP or GDP constitutes a selective switch for Ypt7, but with Yp

177 Ras are specific to bound nucleotide (GTP or GDP), and we provide a structural basis for this.

178 likely reflect intrinsic curvature of GTP or GDP.Pi tubulin and provide structural insights into the

179 depolymerization by the presence of a GTP or GDP/Pi cap.

180 y binds GTP-tubulin at microtubule ends over GDP-tubulin in the mature microtubule lattice, and ATP h

181 domestic product by purchasing power parity (GDP [PPP]) to US$24 800 and witnessing a 6-year increase

182 actor 1 (TRF1) and the non-PARylated partner GDP-mannose 4,6-dehydratase (GMD).

183 into components associated with population, GDP, heating and cooling, and the carbon intensity of en

184 We also discovered that SidI possesses GDP-dependent glycosyl hydrolase activity and that this

185 tabilized MTs, which mimic the EB1-preferred GDP-Pi state of polymerized tubulin.

186 In addition, we found that Tau prefers GDP-like tubulin conformations, which implies that Tau b

187 Gross domestic product (GDP) and derived metrics such as productivity have been

188 indicators, such as Gross Domestic Product (GDP) and unemployment rate, are also driven-forces for p

189 ibutions to be 3% of gross domestic product (GDP) for Cote d'Ivoire, 0.4% for Malawi, and 0.7% for Se

190 Increasing Gross Domestic Product (GDP) growth rates alone cannot restore absolute mobility

191 example, per capita gross domestic product (GDP) has been reduced 17-31% at the poorest four deciles

192 uting at least 3% to gross domestic product (GDP) in the UK and the US.

193 ries with per capita gross domestic product (GDP) over $10,000 US dollars (USD) were used to assess v

194 (per PWID per year), gross domestic product (GDP) per capita (US$1000), and sexual and injecting risk

195 ion with planning by gross domestic product (GDP) per capita or human development index (HDI) in 10-1

196 5% of each country's gross domestic product (GDP) per capita per DALY averted, at a vaccine price of

197 performance based on gross domestic product (GDP) per capita, allowing us to identify countries whose

198 tabase, we extracted gross domestic product (GDP) per capita, also covering 46 years, and Development

199 associated with city gross domestic product (GDP) per capita, but we found no relationship between GD

200 dependent variables: gross domestic product (GDP) per capita, crude or age-standardised incidence, cr

201 3 times the current gross domestic product (GDP) per capita.

202 country's per capita gross domestic product (GDP) per disability-adjusted life-year (DALY) averted.

203 trophic spending and gross domestic product (GDP) per person, the Gini coefficient for income inequal

204 ountries' per capita gross domestic product (GDP) rises using logistic and linear fixed-effect regres

205 mage and a country's gross domestic product (GDP) with a multiple logistic regression analysis.

206 20% of the national gross domestic product (GDP), are responsible for ~75% of GED attributable to ec

207 proaching 18% of the gross domestic product (GDP).

208 hasing power parity) gross domestic product (GDP).

209 impacts per unit of gross domestic product (GDP).

210 I 1.8-1.9) of global gross domestic product (GDP).

211 on of each country's gross domestic product (GDP).

212 country development (gross domestic product [GDP] per capita or Human Development Index [HDI]); natio

213 nd economic factors (gross domestic product [GDP] per capita, prevalence of inequality and poverty, a

214 ment Index [HDI] and Gross Domestic Product [GDP]) using linear regression analysis.

215 on in 1996 (13.3% of gross domestic product [GDP]; $5259 per person) to an estimated $3.1 trillion in

216 trajectories of the Global Drifter Program (GDP) data set, it was found that oceanic eddies are asym

217 Small GTP-binding protein GDP-dissociation stimulator (SmgGDS) proteins are chaper

218 genes encoding either POFUT2 or the putative GDP-fucose transporter (NST2) resulted in loss of MIC2 O

219 tide exchange factor (GEF, Mon1-Ccz1), a Rab-GDP dissociation inhibitor (GDI) complex (prenylated Ypt

220 Finally, Rab9-GDP expression did not affect adrenergic-mediated calciu

221 d when a dominant-negative Rab9 mutant (Rab9-GDP) was employed.

222 -interacting protein 2 (FNIP2), and the RagA(GDP):RagC(GTP) GTPases as they exist in the starved stat

223 RC1 and explains why only the RagA(GTP)/RagC(GDP) nucleotide state binds mTORC1.

224 e assembly of the full-length RagA(GTP):RagC(GDP) dimer bound to Ragulator at 16 A resolution, reveal

225 K27 binds preferentially to the inactive Ras GDP form with a Kd of 4 nM and structural studies suppor

226 he NF1-LRD fails to hydrolyze Ras-GTP to Ras-GDP, suggesting that its suppressive function is indepen

227 ich has RNA-dependent RNA polymerase (RdRp), GDP polyribonucleotidyltransferase and cap-specific meth

228 spending was positively associated with real GDP (beta=0.68 [95% CI 0.24-1.13], p=0.0036), while the

229 01) were both inversely associated with real GDP.

230 BB4b, vimentin), only antibodies against Rho GDP-dissociation inhibitor 2 (ARHGDIB) (adjusted MFI [aM

231 cyte plasma membrane-associated protein, Rho GDP-dissociation inhibitor 2 [ARHGDIB], Rho guanine nucl

232 at mTORC2-AKT signalling is activated by Rho-GDP.

233 Furthermore, Rho-GDP rescues defects in both mTORC2-mediated AKT phosphor

234 emoattractant-induced phosphorylation of Rho-GDP at S192 by GSK-3.

235 h purified proteins, we demonstrate that Rho-GDP promotes AKT phosphorylation by assembling a superco

236 rization in early G1 in the presence of Rsr1-GDP.

237 Here, we show that Rsr1-GDP interacts with the scaffold protein Bem1 in early G1

238 essary for the association of Bem1 with Rsr1-GDP.

239 erty equating to more than 6% of the state's GDP and 600,000 people could be impacted by dynamic floo

240 We propose that Tau's GDP preference allows the cell to independently regulate

241 Our structural analysis revealed that six GDP nucleotides bound the enzyme in close proximity to a

242 s studies on MTL biosynthesis have suggested GDP-D-erythro-alpha-D-gluco-octose and GDP-D-alpha-D-lin

243 ains more of the variation in mortality than GDP.

244 KIF1A binds more weakly to GTP-tubulin than GDP-tubulin and competes with end-binding (EB) proteins

245 e results gave a preliminary indication that GDP may possibly inhibit the hepcidin-FPN interactions.

246 the nucleotide interaction and revealed that GDP is required for activity.

247 These results suggest that GDP a promising natural small-molecule inhibitor that ta

248 The GDP polyribonucleotidyltransferase (PRNTase) domain of t

249 bit large conformational changes in both the GDP- and the GTP-bound systems, but in the GTP-bound Cdc

250 its beta sheet core, thereby dismantling the GDP binding site.

251 by the liberation of bound water during the GDP- to GTP-bound transition.

252 To determine how the GDP-glucose is generated, we characterized three candida

253 Our results confirmed that MTs in the GDP state generally have weaker lateral interactions bet

254 has larger conformational flexibility in the GDP-bound Cdc42 than in the GTP-bound Cdc42.

255 tructure of ObgE at 1.85-A resolution in the GDP-bound state, showing the characteristic N-terminal d

256 We propose that conversion of ARF6 into the GDP-bound form in the apical domain of hair cells is ess

257 present the crystal structure of an NST, the GDP-mannose transporter Vrg4, in both the substrate-free

258 changes might lead to the deformation of the GDP-binding pocket.

259 omain, leading to a severe disruption of the GDP-binding site.

260 from Galphas along with the structure of the GDP-bound Gs heterotrimer.

261 Overexpression of the GDP-locked Rsr1 interferes with Bem1-dependent Exo70 pol

262 refers the GTP-bound while SIRT2 prefers the GDP-bound ARF6.

263 -4/Myrlysin, a subunit of BORC, promotes the GDP-to-GTP exchange of ARL-8 in vitro and recruits ARL-8

264 t the apo conformation does not resemble the GDP-bound state.

265 in contrast to the prevailing view that the GDP-bound forms of G proteins are inactive, our study re

266 After conversion to the GDP-bound state, RhoJ shifts from PlexinD1 to VEGFR2, wh

267 As a result, when the GDP state tubulin dimer is exposed at the growing MT end

268 GTP-bound) Rac1 without interacting with the GDP-bound inactive form.

269 re-guided mutagenesis of residues within the GDP-binding pocket identified Arg(93) as playing a key r

270 Rab11 and Rab8, together with their GDP-GTP exchange factors (GEFs), TRAPP-II and Rabin8, pr

271 n KIF1A that reduces preferential binding to GDP- versus GTP-rich microtubules disrupts SVP delivery

272 termined crystal structures of YcjX bound to GDP and GDPCP, respectively, which crystallized in three

273 s that gets disrupted when Cdc42 is bound to GDP, a disruption that does not exist in other Rho GTPas

274 GTP in the eIF2*GTP*Met-tRNAiMet complex to GDP and Pi.

275 icator for aviation's direct contribution to GDP in both the UK and the US.

276 ave historically grown with a correlation to GDP, and there is limited evidence of near-term global d

277 th proteins were able to salvage l-fucose to GDP-fucose.

278 quisition of GTP (GEFs) or its hydrolysis to GDP (GAPs).

279 ion of GDP-D-erythro-alpha-D-gluco-octose to GDP-D-alpha-D-lincosamide have not yet been elucidated.

280 onvert GDP-D-erythro-alpha-D-gluco-octose to GDP-D-alpha-D-lincosamide.

281 NA (pRNA) from 5'-triphospho-RNA (pppRNA) to GDP via a covalent enzyme-pRNA intermediate to generate

282 ica was the most affected region relative to GDP and also the largest contributor to global absolute

283 tivities, and that introducing a bias toward GDP tubulin has little impact on the observed MT stabili

284 own the rearrangements in the ribosome-EF-Tu-GDP-Pi-Lys-tRNA(Lys) complex following GTP hydrolysis by

285 transit the accommodation corridor for EF-Tu.GDP to release.

286 om streptomycetes is unusual in that it uses GDP-glucose as the donor substrate rather than the more

287 pppA formation and pRNA transfer assay using GDP analogues as pRNA acceptors indicated that the PRNTa

288 ished how S. venezuelae can make and utilize GDP-glucose in the biosynthesis of trehalose 6-phosphate

289 tor specificity of VSV PRNTase using various GDP analogues and identified chemical groups of GDP as e

290 To test whether GDP-fucose itself was essential for Leishmania viability

291 om the fungal pathogen Candida albicans with GDP and Mg2+ in the active site.

292 Under the lowest estimation, and with GDP and total country population as model predictors, th

293 the age profile of PWID was associated with GDP and urbanisation.

294 significantly and positively associated with GDP per capita, and most are correlated with the share o

295 an FUT8 in the apo state and in complex with GDP, a mimic of the donor substrate, and with a glycopep

296 mocratic experience were not correlated with GDP per capita between 1995 and 2015 (rho=-0.1036; p=0.1

297 phic payments was correlated positively with GDP per person and the share of GDP spent on health, and

298 er, then the ICER would be less than the 1 x GDP per capita threshold and thus very cost effective.

299 The structure of the yeast GDP-mannose transporter, Vrg4, revealed a requirement fo

300 Whereas only AFKP80 yielded GDP-d-Arap from exogenous d-Arap, both proteins were abl