ライフサイエンスコーパス: Gly

1 Gly to Ser mutations within the two Gly residues in the

2 Gly-4941 replacement with Lys resulted in channels havin

3 ed only in active group (Bet v 1: P = 0.054, Gly m 4: P = 0.037), and no relevant changes occurred fo

4 inal residues of the chemokine XCL1 (Val(1), Gly(2), Ser(3), and Glu(4)) contribute a large fraction

5 RAS mutations (such as at residues Gly(12), Gly(13), and Gln(61)) have the same impact on RAS signal

6 Because Val-17, Gly-22, Leu-25, Asn-26, and Pro-29 are predicted to resi

7 sp at position 177, Gln/Glu at position 180, Gly/Arg at position 239, and Pro/Ser at position 280.

8 (241) alleles) and CELA3B ( approximately 2% Gly(241) alleles) points to individual variations in com

9 PyC(2)-Gly concentrations were highest in fruits and root veget

10 PyC(2)-Gly was found at the highest concentrations and most wid

11 Five PyC types were detected with PyC(2)-Gly, PyC(3)-Gly and PyC(2)-Ala at quantifiable concentra

12 In addition, substitution of Gly-245, Gly-247, and Gly-250 affects the amount of PutP in the m

13 has three amino acid substitutions (Cys(27), Gly(608), and Pro(671)) within the full-length molecule.

14 types were detected with PyC(2)-Gly, PyC(3)-Gly and PyC(2)-Ala at quantifiable concentrations.

15 MP15 finger residues at this site (Arg(301), Gly(304), His(307), and Met(369)) enable potent activati

16 nd to the morphine and D-Ala(2), N-MePhe(4), Gly-ol]-enkephalin (DAMGO) nonbiased agonists and to the

17 ivation by morphine or [d-Ala(2),N-MePhe(4), Gly-ol]enkephalin (DAMGO) causes differences in spatiote

18 ioid receptor agonist [D-Ala(2), NMe-Phe(4), Gly-ol(5)]-enkephalin produces paradoxical behavioural r

19 n of a highly selective OXTR agonist [Thr(4),Gly(7)]-OXT to hippocampal slices resulted in an acute a

20 d phage-displayed peptide libraries Ser-[X]4-Gly-Gly-Gly, with Gly and Ser encoded using unique combi

21 he use of 0.5% Ca(2+), 0.75% Gly(1) and 7.5% Gly(2) is suggested as the optimum condition.

22 t, contrary to previous reports, the Asp(614)Gly mutation in the spike glycoprotein (S) likely reduce

23 Analogues 69 ([Gly(2),Nle(10),D-Thi(11),Phe(16)]hGLP-2-(1-30)-NH2), 72

24 ),D-Thi(11),Phe(16)]hGLP-2-(1-30)-NH2), 72 ([Gly(2),Nle(10),D-Phe(11),Leu(16)]hGLP-2-(1-33)-OH), 73 (

25 0),D-Phe(11),Leu(16)]hGLP-2-(1-33)-OH), 73 ([Gly(2),Nle(10),D-Phe(11),Leu(16)]hGLP-2-(1-33)-NH2), 81

26 repared films, the use of 0.5% Ca(2+), 0.75% Gly(1) and 7.5% Gly(2) is suggested as the optimum condi

27 ing residues from RasGRP1/3 (Thr(7), Tyr(8), Gly(19), and Leu(21), respectively) conferred potent bin

28 The first new element (Gly-807-Gly-811) is short distance element on the C-terminal sid

29 ),D-Phe(11),Leu(16)]hGLP-2-(1-33)-NH2), 81 ([Gly(2),Nle(10),D-Phe(11),Leu(16)]hGLP-2-(1-33)-NHEt), an

30 he(11),Leu(16)]hGLP-2-(1-33)-NHEt), and 85 ([Gly(2),Nle(10),D-Phe(11),Leu(16)]hGLP-2-(1-33)-NH-((CH2)

31 ntains an RRM domain at the N terminus and a Gly-rich domain at the C terminus.

32 Mutations at a Gly residue (Gly150) that modulate helical mobility redu

33 proRaxX is cleaved at a Gly-Gly motif, yielding a mature peptide that retains th

34 ndwiched between two neighboring glycines (a Gly-Arg-Gly, or "GRG," sequence).

35 lk allergy with the oral administration of a Gly-m-Bd-30K soy-derived peptide that contains cross-rea

36 nal studies, reveal how the flexibility of a Gly-Met-Gly (GMG) motif in the unwound region of transme

37 homologs which contained either an Ile or a Gly at this location and showed that only the Gly-contai

38 The consequences of replacing a Gly by Ser at each position in the required (Gly-Xaa-Yaa

39 -Ser, -Val and the three achiral amino acids Gly, beta-Ala, and GABA).

40 fusion protein by inserting mNeonGreen after Gly-134.

41 cids in all fractions were dominated by Ala, Gly, Glu and Ser.

42 ated three mutant forms (I14X; X = Val, Ala, Gly) of the enzyme that have increased active site flexi

43 I viral fusion proteins, including high Ala/Gly content, intermediate hydrophobicity, and few charge

44 ny dose level, sIgE/IgG4 against Bet v 1 and Gly m 4.

45 glucose homeostasis (GLUT-4, G6PDH, Hk-2 and Gly-Syn-1).

46 ructure analysis, we identified Arg(237) and Gly(239) residues on the S2 of the VSD that form direct

47 ition, substitution of Gly-245, Gly-247, and Gly-250 affects the amount of PutP in the membrane.

48 and with the peptide backbone of Ser-328 and Gly-329 from both subunits.

49 lix has two conserved glycines, Gly-4934 and Gly-4941, that facilitate RyR1 channel gating by providi

50 Substitution of Tyr for Ala and Gly in ADS1.2 and ADS1.4, respectively, blocked their ab

51 opsis, ADS1.2 and ADS1.4, which have Ala and Gly, respectively, in place of the gatekeeping Tyr found

52 0), including a preference for Ser, Arg, and Gly at the +1 and a preference for Arg at the +7 positio

53 ATP and Gly induced common, but also specific, alternative modes

54 ATP and Gly triggered changes in the expression of the genes inv

55 helial lineage markers (CD45, CD31, CD14 and Gly-A) and the epithelial marker EpCAM.

56 The role of GalT2 and Gly in the Fap1 glycosylation is unknown.

57 emonstrate abnormally elevated brain Glu and Gly levels in patients with first-episode psychosis by m

58 Significantly higher Glu and Gly levels were found in both the anterior cingulate cor

59 Glu and Gly levels were measured in vivo in the anterior cingula

60 Glu and Gly levels were positively correlated in patients.

61 he or Leu at the C-terminal P2' position and Gly in the P6 position.

62 Peptides carrying multiple Pro and Gly (residues with lowest helical propensity) retain str

63 cosylation by adding a rhamnose residue, and Gly mediates the final glycosylation step by transferrin

64 cosylation by adding a rhamnose residue, and Gly mediates the final glycosylation step by transferrin

65 tagging") of LPXTG-containing substrates and Gly-terminated nucleophiles occurs in vitro as well as i

66 Although Arg-Gly-Asp (RGD) integrin ligand and matrix softening confe

67 independently of IGF binding through an Arg-Gly-Asp (RGD) integrin-binding motif.

68 C3 harbors an Arg-Gly-Asp (RGD) motif, which is the major integrin-binding

69 ocal stresses on the cell surface via an Arg-Gly-Asp-coated magnetic bead.

70 r protein that binds RNA through RRM and Arg-Gly-Gly (RGG) motifs.

71 classes of integrins: collagen-binding, Arg-Gly-Asp (RGD)-binding, laminin-binding, and leukocyte in

72 between two neighboring glycines (a Gly-Arg-Gly, or "GRG," sequence).

73 d lipid domains increased beta1-integrin-Arg-Gly-Asp-peptide affinity and valency, thus implicating L

74 elial cells, BA increased beta1-integrin-Arg-Gly-Asp-peptide affinity by 18% with a transition from s

75 ful intermediates for the preparation of Arg-Gly-Asp (RGD)-based cyclopentapeptides (cRGD) with nanom

76 th a higher affinity compared with other Arg-Gly-Asp binding integrins.

77 and two positively charged domains (Pro-Arg-Gly) at both N- and C-termini.

78 In contrast, the putative Arg-Gly-Asp (RGD)-binding alphaPAT-2/betaPAT-3 integrin was

79 cription was effectively blocked by RGD (Arg-Gly-Asp) peptide and neutralizing alphavbeta3 antibodies

80 We previously demonstrated that Arg-Gly-Asp (RGD)-containing ligand-mimetic inhibitors of in

81 Cyclic peptides containing the Arg-Gly-Asp (RGD) sequence have been shown to specifically b

82 Peptides containing the Arg-Gly-Asp (RGD) sequence have high affinity for alphavbeta

83 The Arg-Gly-Gly repeats within the low-complexity region are req

84 migration by targeting integrins, using Arg-Gly-Asp (RGD) peptide-functionalized gold nanorods.

85 around Gly(3)-Phe(4) and a gamma-turn around Gly(2), providing spectroscopic evidence for the formati

86 characterized by a type II' beta-turn around Gly(3)-Phe(4) and a gamma-turn around Gly(2), providing

87 e O-acetyltransferase uses a similar Gly-Asp-Gly-Ile motif to form the "cysteine synthase" complex wi

88 semitryptic peptide arising from cleavage at Gly(2196)-Leu(2197) We noted that this scissile bond is

89 The experimental results of ligation at Gly junction and regioselective ligation at Glu junction

90 its extracellular ligand-binding repeats at Gly(171) Asp(172).

91 Examination of aza-Gly-Pro and aza-Phe-Pro analogs 2a and 2b in a murine pr

92 MD simulations suggested that bulkier Gly -> Xaa substitutions differentially disrupt the CMP-

93 ed through multiple amino acid residues, but Gly-171 and Leu-175 of P2 were more critical.

94 ng group with N-(4-(p-chlorophenyl)butanoyl)-Gly and N-(4-(p-methoxyphenyl)butanoyl)-Gly albumin-bind

95 6 bearing the N-(4-(p-chlorophenyl)butanoyl)-Gly and N-(4-(p-methoxyphenyl)butanoyl)-Gly motifs, resp

96 oyl)-Gly and N-(4-(p-methoxyphenyl)butanoyl)-Gly albumin-binding motifs generated HTK03121 and HTK031

97 oyl)-Gly and N-(4-(p-methoxyphenyl)butanoyl)-Gly motifs, respectively, had relatively faster tumor ac

98 al exchange of Gln/Glu at position 180 or by Gly/Arg at position 239.

99 y charged Arg, Lys, Glu, and Asp residues by Gly or His.

100 XAT contains a canonical Gly-Asp-Ser-Leu (GDSL) motif and is encoded by a member

101 lasmic linker protein 170 (CLIP170) is a CAP-Gly domain-containing protein that is associated with th

102 lanine substitution of the conserved central Gly(6)-Gln(7) residues or by random sequence scrambling

103 Moreover, DTD's activity on non-cognate Gly-tRNA(Ala) is conserved across all bacteria and eukar

104 ent breaks ~20% of the time, two consecutive Gly substitutions break the helix ~65% of the time.

105 The consequent Gly-tRNA(Gly) 'misediting paradox' is resolved by EF-Tu

106 An absolutely conserved Gly in the middle of the alpha1-helix of betaI helps mai

107 is highly preferred for binding to conserved Gly:Asp:Asn residues.

108 tics, a series of GLP-2 analogues containing Gly substitution at position 2, norleucine in position 1

109 In contrast, Gly replacements N-terminal to the GFPGER sequence, up t

110 In contrast, Gly-22 in the motif could be substituted by other small

111 whereas a low response of the corresponding Gly-4934 variants suggested loss of function.

112 N-unsubstituted alpha-amino acids, dipeptide Gly-Gly, and also benzylamine were used as the amine com

113 N-terminal peptidase C39 domain at a double Gly motif.

114 The first new element (Gly-807-Gly-811) is short distance element on the C-term

115 irulence peptide 1 (vp1), a highly expressed Gly-Gly peptide-encoding gene in chinchilla middle ear e

116 ttings drives the expansion of KP expressing Gly-Asp insertion mutants, despite an associated fitness

117 e RetGC1 binding site, insertion of an extra Gly residue between Ser-173 and Leu-174 as well as delet

118 Through a facile Gly to Pro substitution, we have altered backbone dynami

119 mbrane and coiled coil regions by a flexible Gly-rich linker.

120 leading to a detection limit of ~3 mg/mL for Gly.

121 with reduced amino acid diversity, foremost Gly, Ser, and Thr.

122 optimized protocol used to remove Fmoc from Gly residue was proved by the synthesis of Leu-enkephali

123 the dynamics of the major amino acids, e.g., Gly, remained unaltered with respect to parity.

124 GlcN-Gly caramels generated the greatest amount of butterscot

125 ty of the GlcN-amino acid combinations; GlcN-Gly and GlcN-Ser were best discriminated.

126 n-473 is positioned on a short loop (Asn-Gln-Gly-Glu-Pro) instead of an alpha-helix and forms hydroge

127 (TTLL5) glutamylates RPGR(ORF15) in its Glu-Gly-rich repetitive region containing motifs homologous

128 of RPGR (RPGR(ORF15)), carrying multiple Glu-Gly tandem repeats and a C-terminal basic domain of unkn

129 displayed peptide libraries Ser-[X]4-Gly-Gly-Gly, with Gly and Ser encoded using unique combinations

130 Glycine (Gly) is used as a model system to evaluate the ability o

131 uantify in vivo glutamate (Glu) and glycine (Gly) levels in patients with first-episode psychosis as

132 Using glycine (Gly) as an example, we demonstrate a novel method to acc

133 to occur exclusively at N-terminal glycines (Gly).

134 ore-lining helix has two conserved glycines, Gly-4934 and Gly-4941, that facilitate RyR1 channel gati

135 Glycoaldehyde (Gly) represents a prototypical system to identify the re

136 Among the small peptides 2-31, (H)Gly-Gly-Phe-Leu(OMe) (30) reduced prostaglandin producti

137 bundle), for the active dimer (right-handed Gly-zipped TMD2/TMD2 dimer), and for the full-length pin

138 The disease-linked mutation of the hinge Gly(86), leading to abnormally high affinity for the tar

139 SIC1 that includes the highly conserved 'His-Gly' (HG) motif.

140 work (MOF) based on the tripeptide Gly-l-His-Gly (GHG) for the enantioselective separation of metamph

141 ructural explanation for the role of the His-Gly dipeptide in the structure and function of ASICs.

142 omprising a formamidinylated, N-hydroxylated Gly-Gln dipeptide conjugated to 6'-amino-pseudouridine.

143 unit through sequential additions of Pro-Hyp-Gly triads, we achieved sub-angstrom tuning over the 2D

144 ing in collagen peptides composed of Pro-Hyp-Gly triplet repeats, allowing for truncation to the smal

145 sequence comprising a central block (Pro-Hyp-Gly) and two positively charged domains (Pro-Arg-Gly) at

146 photorespiratory CO(2) release and impaired Gly-to-Ser turnover after a shift from high-to-low CO(2)

147 ft from high-to-low CO(2) without changes in Gly decarboxylase (GDC) gene or protein expression.

148 Systematic mutation of tyrosine residues in Gly/Ser-Tyr-Gly/Ser motifs of the IDR reduced this effec

149 h 18 of the 20 common amino acids, including Gly, Ala, Ser, Thr, Asp, and Glu, which are relatively s

150 FmhC pair with FemA and FemB to incorporate Gly-Ser dipeptides into cross-bridges and to confer resi

151 presence and absence of the fibrin inhibitor Gly-Pro-Arg-Pro.

152 nd sterically hindered amino acid junctions (Gly, Ala, Trp, Glu).

153 The peptides were rich in Glu, Asp, Lys, Gly and Leu, and also exhibited diverse bioactivities, a

154 We identify a Lys-Gly-Glu (KGE) integrin-binding motif in the FVIIa protea

155 ies, reveal how the flexibility of a Gly-Met-Gly (GMG) motif in the unwound region of transmembrane s

156 mming included a higher rate of metabolizing Gly, which provides additional evidence that the metabol

157 architecture can efficiently edit mischarged Gly-tRNA(Ala) species four orders of magnitude more effi

158 eased photosynthesis, and up to 54-fold more Gly alongside several redox-stress-related metabolites.

159 conformation, whereas in the CD loop mutant "Gly-loop", the original network of interactions between

160 y the parasite-secreted kinase WNG1 (With-No-Gly-loop) as a critical regulator of tubular membrane bi

161 bands from PAGE gels reveal an abundance of Gly/Ala/Ser/Thr repeats exemplified by a prominent, prev

162 supplemented with varying concentrations of Gly were obtained, and a range of data analysis methods

163 was also partially rescued upon deletion of Gly-457.

164 Here, the effect of Gly replacements within and nearby the integrin binding

165 We critically examine the effect of Gly-to-d-Ala substitutions on protein stability using ex

166 However, the importance of Gly-221 for HABP2 activity is unclear.

167 he presence of the proximal l-Ala instead of Gly in the common configuration of the peptide side chai

168 d ultrastructure, and tissue localization of Gly decarboxylase subunit P (GLDP) in nine Neurachninae

169 ely 10% in comparison to benchmark method of Gly-PseAAC.

170 mpact of deletion and replacement mutants of Gly-457 and its two adjacent residues in GAT-1.

171 s on overlapping and recombinant peptides of Gly-m-Bd-30K by SPOT and cell proliferation assays.

172 Replacement of Gly residues C-terminal to GFPGER did not affect integri

173 21A, and G221S mutants to assess the role of Gly-221 in HABP2 catalysis.

174 ined by deleting positions on either side of Gly-457.

175 Crystal structures of Gly-AMP, Pro-AMP, betaPro-AMP and Phe-AMP bound to RNase

176 null effect observed for the small subset of Gly-to-d-Ala substitutions which are not stabilizing.

177 In addition, substitution of Gly-245, Gly-247, and Gly-250 affects the amount of PutP

178 Here, we report that substitution of Gly-4941 with Asp or Lys results in functional channels

179 hexapeptide and several regions upstream of Gly(215) that comprise residues of the interface surface

180 The replacement of one Gly in the essential repeating tripeptide sequence of th

181 examined using various amino acids, and only Gly required the optimization of the Fmoc removal cockta

182 Mutation of Glu-87 to Ala or Gly rendered the protein constitutively active as a kina

183 ants in which Tyr-15 is replaced with Ala or Gly, respectively, are monomeric.

184 ing every amino acid residue to Val, Ala, or Gly, and then screening the drug resistance phenotypes o

185 abolism (2-hydroxybutanoic acid, oxoproline, Gly, and Glu) were altered in UCP3 Tg mice across all tr

186 very different distributions of FAA- and PAA-Gly.

187 rial proteins in mtacp mutants, particularly Gly decarboxylase, affects the recovery of photorespirat

188 We found that PB-Gly-Taxol bound the target protein beta-tubulin with bot

189 }(Ac) wheel with glycolate ligands, {Pd84 }(Gly) , and the next in a magic number series for this cl

190 To our knowledge, the peptides Gly-Pro-Ala-Val, Val-Cys, and Phe-Phe have not been prev

191 apeptide H(2)N-(CH(2))(4)-CO-Pro-Leu-Arg-Phe-Gly-Ala-NH-CH(2)-Fc is the optimal probe for cathepsin B

192 trinsically disordered proteins, such as Phe-Gly repeat domains, alters drastically when they are con

193 ibutions of the activation loop, the Asp-Phe-Gly (DFG) motif, the regulatory spine, and the gatekeepe

194 type I inhibitors assume an active "Asp-Phe-Gly (DFG)-in" and "alphaC-in" conformation.

195 N-Cl-Tyr-Gly, N,N-di-Cl-Tyr-Gly, N-Cl-Phe-Gly, N,N-di-Cl-Phe-Gly, N-Cl-Tyr-Ala, and N,N-di-Cl-Tyr-

196 N-Cl-Tyr-Gly, N,N-di-Cl-Tyr-Gly, N-Cl-Phe-Gly, N-Cl-Tyr-Ala, and N,N-di-Cl-Tyr-Ala along with thei

197 N-di-Cl-Tyr-Gly, N-Cl-Phe-Gly, N,N-di-Cl-Phe-Gly, N-Cl-Tyr-Ala, and N,N-di-Cl-Tyr-Ala were identified

198 le Phe-Gly formed only N-Cl-/ N, N-di-Cl-Phe-Gly.

199 e in water over 10 days except N,N-di-Cl-Phe-Gly.

200 tification of three dipeptides, Tyr-Gly, Phe-Gly, and Tyr-Ala, from raw water demonstrates a useful a

201 the small hydrophobic peptide Z-d-Phe-l-Phe-Gly (FIP) was shown to block MeV infections and syncytiu

202 The inhibitors carbobenzoxy (Z)-d-Phe-l-Phe-Gly (fusion inhibitor peptide [FIP]) and 4-nitro-2-pheny

203 ine and M is a given monosaccharide), [l-Phe-Gly + M + H](+) (where l-Phe-Gly is l-phenylalanine-glyc

204 phenylalanine-glycine), and [Mn(II) + (l-Phe-Gly - H) + M](+) complex ions are used to determine coll

205 haride), [l-Phe-Gly + M + H](+) (where l-Phe-Gly is l-phenylalanine-glycine), and [Mn(II) + (l-Phe-Gl

206 t to the inhibitory effects of Z-d-Phe-l-Phe-Gly.

207 nine (Tyr-Ala), and phenylalanylglycine (Phe-Gly), reacted with sodium hypochlorite, and these reacti

208 romatic dipeptides, phenylalanylglycine (Phe-Gly), tyrosylalanine (Tyr-Ala), and tyrosylglycine (Tyr-

209 , and N-Cl-3-I-tyrosyl dipeptides, while Phe-Gly formed only N-Cl-/ N, N-di-Cl-Phe-Gly.

210 Since only subsets of Phe/Gly motifs, particularly those within Nup62, Nup98, and

211 ing infection, including the cleavage of Phe/Gly-containing nucleoporin proteins (Nups) within nuclea

212 teins, hyperaccumulation of photorespiratory Gly, and reduced accumulation of many intermediates in c

213 fied that calpain-1 cleaves hERG at position Gly-603 in the S5-pore linker of hERG.

214 we report that the matrikine acetylated Pro-Gly-Pro (PGP) stimulates vascular inflammation through a

215 degrading the neutrophil chemoattractant Pro-Gly-Pro (PGP) and rationalized that the failure of conve

216 e traditional beta-turn motifs such as d-Pro-Gly, both the 2-Abz and d-Phe rings may be further funct

217 These reactions build up H2N-Pro-Gly-Ala-CONHL and H2N-Cys-His-Asp-CONHL (where L = organ

218 d inactivates the chemotactic tripeptide Pro-Gly-Pro.

219 highly selective CCK-2R agonist by replacing Gly in a CCK-8 derivative with Glu.

220 tic peptides (CMPs) with previously reported Gly -> Xaa (Xaa = Ala, Arg, or Val) vEDS substitutions w

221 Gly by Ser at each position in the required (Gly-Xaa-Yaa)6 Fn-binding sequence are probed here, using

222 oncogenic RAS mutations (such as at residues Gly(12), Gly(13), and Gln(61)) have the same impact on R

223 O prosthetic group created from (189)Ala-Ser-Gly(191) residues and the bound l-phenylalanine and l-ty

224 played enhanced innervation in mice on a Ser/Gly-free diet.

225 Ser (exSer)-dependent PDAC cells during Ser/Gly (glycine) deprivation.

226 li serine O-acetyltransferase uses a similar Gly-Asp-Gly-Ile motif to form the "cysteine synthase" co

227 Whereas a single Gly substitution caused transient breaks ~20% of the tim

228 The method, called SPRINT-Gly, achieved consistent results between ten-fold cross

229 Overall, SPRINT-Gly is 18% and 50% higher in Matthews correlation coeffi

230 triple helix conformation and stabilisation (Gly, Pro, Hyp and Hyl), whilst the Lys content was great

231 modeling showed that the stretch surrounding Gly-457 is likely to form a pi-helix.

232 from Gram-positive bacteria lack C-terminal Gly-Tyr-Gly-Ile motifs, suggesting that they do not inte

233 EC536) CdiA-CT(EC536) inserts its C-terminal Gly-Tyr-Gly-Ile peptide tail into the active-site cleft

234 The N-terminal Gly-rich fragment of rSp0032 and the C-terminal His-rich

235 ond and ligates protein-LPXT to the terminal Gly residue of the nascent cross-bridge of peptidoglycan

236 (i) the critical spacer length (longer than Gly) and (ii) the presence of Ca(2+) and Mg(2+) in all i

237 zation and solid-state assays indicated that Gly replacements at four sites within the Fn-binding seq

238 Whereas previous studies showed that Gly to Ser mutations within an integrin-binding site cau

239 The Gly -> Arg substitution destabilized CMP-alpha(2)I side-

240 The Gly gatekeeper of CDPK1 makes it exquisitely sensitive t

241 The Gly-to-Arg substitution at the 16 position (rs1042713) i

242 Additionally, the Gly-Asp insertion impairs bacterial growth in lactose-co

243 P-alpha(2)I side-chain interactions, and the Gly -> Val change broke the essential Mg(2+) coordinatio

244 s (amino acids [aa] 19 to 40) of p17 and the Gly-rich region of the C terminus of hnRNP A1.

245 omplexed with AMP-PNP reveals a shift in the Gly-rich loop along with domain closure to position the

246 scopy study on the stepwise hydration of the Gly dimer with up to three water molecules.

247 the 2D-IR spectrum allows separation of the Gly spectral signature from that of the dominant protein

248 water which combines the selectivity of the Gly-Gly-His (GGH) peptide probe with the sensitivity of

249 ain, which is defined by the presence of the Gly-X-Y triplet repeats, is amongst the most versatile a

250 ly at this location and showed that only the Gly-containing desaturase was capable of very-long-chain

251 ve the turn where it can form H-bonds to the Gly(3) and C-terminus C horizontal lineO groups.

252 the self-assembly of type I collagen via the Gly-X-Y motif, the molecular mechanism by which enamel m

253 avin N5 and strong H-bond formation with the Gly-141 carbonyl.

254 r ion permeation pathway and buttresses the 'Gly-Ala-Ser' (GAS) constriction, thus providing a struct

255 Molecular dynamics simulations showed these Gly replacements interfered with the interaction of a co

256 Strict L-chiral rejection through Gly-cisPro motif during chiral proofreading underlies th

257 Mutations in ClC-Ka that change Ser(cen) to Gly, Pro, or Thr have only minor effects on anion select

258 dentified a role for one specific tRF-5' tRF-Gly-GCC, or tRF-GG-as a repressor of genes associated wi

259 gth pinholin protein before being triggered (Gly-zipped TMD2/TMD1-TMD1/TMD2 dimer in a line).

260 anic framework (MOF) based on the tripeptide Gly-l-His-Gly (GHG) for the enantioselective separation

261 a subset of tRNAs, including tRNA(Glu), tRNA(Gly), tRNA(Lys), tRNA(Val), tRNA(His), tRNA(Asp), and tR

262 The consequent Gly-tRNA(Gly) 'misediting paradox' is resolved by EF-Tu in the ce

263 unterpart in charging the mitochondrial tRNA(Gly) isoacceptor, which carries a defective TpsiC hairpi

264 m specific tRNA loci (e.g., the nuclear tRNA(Gly) and tRNA(Leu), the mitochondrial tRNA(Val) and tRNA

265 RS efficiently charged the cytoplasmic tRNAs(Gly) of C. elegans, the mitochondrial form was much more

266 rminal catalytic domain (CAT), a central Trp-Gly-Arg (WGR) domain and an N-terminal region (NTR).

267 [BrPhe(22)]sCT(8-32) adopts a type II turn (Gly(28)-Thr(31)), whereas CGRP and AM adopt type I turns

268 omodimers FemA and FemB sequentially add two Gly-Gly dipeptides.

269 Gly to Ser mutations within the two Gly residues in the essential GFPGER sequence prevented

270 polar mixture composed of Leu-Val, Leu-Tyr, Gly-Tyr, and Ala-Tyr dissolved in DMSO-d6/GL (8:2, v/v)

271 Methods: DOTA-D-Glu-Ala-Tyr-Gly-Trp-(N-Me)Nle-Asp-1-Nal-NH(2) (DOTA-MGS5) radiolabel

272 (177)Lu-DOTA-MG11 ((177)Lu-DOTA-dGlu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH(2)) and (177)Lu-DOTA-PP-F11 ((177

273 -DOTA-PP-F11 ((177)Lu-DOTA-(dGlu)(6)-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH(2)), and whether the use of prote

274 DOTA-PP-F11N ((177)Lu-DOTA-(dGlu)(6)-Ala-Tyr-Gly-Trp-Nle-Asp-Phe-NH(2)) performs better than referenc

275 strin analog (177)Lu-DOTA-(d-Glu)(6)-Ala-Tyr-Gly-Trp-Nle-Asp-PheNH(2) ((177)Lu-PP-F11N) is a suitable

276 N-Cl-Tyr-Gly, N,N-di-Cl-Tyr-Gly, N-Cl-Phe-Gly, N,N-di-Cl-Phe-Gly,

277 N-Cl-Tyr-Gly, N,N-di-Cl-Tyr-Gly, N-Cl-Phe-Gly, N-Cl-Tyr-Ala, and

278 N-Cl-Tyr-Gly, N,N-di-Cl-Tyr-Gly, N-Cl-Phe-Gly, N,N-di-Cl-Phe-Gly, N-Cl-Tyr-Ala, and

279 N-Cl-Tyr-Gly, N,N-di-Cl-Tyr-Gly, N-Cl-Phe-Gly, N-Cl-Tyr-Ala, and N,N-di-Cl-Tyr-Ala a

280 and quantification of three dipeptides, Tyr-Gly, Phe-Gly, and Tyr-Ala, from raw water demonstrates a

281 the carbonyl groups from the Thr-Val-Gly-Tyr-Gly signature filter sequence and the permeant ions gene

282 am-positive bacteria lack C-terminal Gly-Tyr-Gly-Ile motifs, suggesting that they do not interact wit

283 diA-CT(EC536) inserts its C-terminal Gly-Tyr-Gly-Ile peptide tail into the active-site cleft of CysK

284 which recognizes the pan-opioid sequence Tyr-Gly-Gly-Phe at the N terminus of most endogenous opioid

285 mutation of tyrosine residues in Gly/Ser-Tyr-Gly/Ser motifs of the IDR reduced this effect, depending

286 three model dipeptides, tyrosylglycine (Tyr-Gly), tyrosylalanine (Tyr-Ala), and phenylalanylglycine

287 ylalanine (Tyr-Ala), and tyrosylglycine (Tyr-Gly), under chloramination in the presence of Br(-) and

288 ceptor ligand, analogs H-Tyr-c[D-Lys-Xxx-Tyr-Gly] were synthesized and their biological activity was

289 largely undetectable in the effluent unless Gly-Pro-Arg-Pro (GPRP) was added to block fibrin polymer

290 endent on stretches of rare codons, Leu(UUA)-Gly(GGU)-Val(GUA).

291 aniline-diglycolic acid-DPhe-Gln-Trp-Ala-Val-Gly-His-Leu-NHEt), showing excellent tumor localizing ef

292 rboxymethyl-piperidine-d-Phe-Gln-Trp-Ala-Val-Gly-His-Sta-Leu-NH2 ((68)Ga-RM2) is a synthetic bombesin

293 rboxymethyl-piperidine-D-Phe-Gln-Trp-Ala-Val-Gly-His-Sta-Leu-NH2 ((68)Ga-RM2) is a synthetic bombesin

294 between the carbonyl groups from the Thr-Val-Gly-Tyr-Gly signature filter sequence and the permeant i

295 he evolutionary replacement of Ala(241) with Gly.

296 Constructs with Gly to Ser substitutions within and nearby the inserted

297 peptide libraries Ser-[X]4-Gly-Gly-Gly, with Gly and Ser encoded using unique combinations of codons

298 y in the M9-glucose medium supplemented with Gly.

299 protocols for the preparation of various Xaa-Gly dipeptide surrogates in the form of Xaa-psi[triazole

300 % MS SI restoration for the Z-Gly-Gly-Val and bradykinin peptides were 75-83% while %