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1 included in the study (196 Gram-positive, 44 Gram-negative, 32 polymicrobial, and 29 non-VG targets),
8 ch we call 'necrosignaling', exists in other Gram-negative and Gram-positive bacteria and displays sp
10 ics), a high-throughput scRNA-seq method for Gram-negative and Gram-positive bacteria that can resolv
11 ficant photoinactivation (up to 95%) against Gram-negative and Gram-positive bacteria was observed wh
12 I-seq captures single-cell transcriptomes of Gram-negative and Gram-positive bacteria with high purit
13 of positive blood cultures in patients with Gram-negative and Gram-positive bacteria, including 8/60
14 ed the presence of RgNanOx homologues across Gram-negative and Gram-positive bacterial species and co
15 l and cytokine inflammatory response between Gram-negative and Gram-positive BK and to determine the
17 bactericidal activity extends to a range of Gram-negative and Gram-positive wound pathogens in plank
18 positive culture of more virulent bacteria (gram-negative and other gram-positive groups) and presen
21 d bloodstream infection due to nonfermenting Gram-negative bacilli (odds ratio, 6.33; 95% CI, 1.59-25
22 a caused by gram-positive cocci, susceptible gram-negative bacilli (sGNB), resistant GNB (rGNB), and
23 lar catheter infections due to nonfermenting Gram-negative bacilli was high for the femoral insertion
24 related bloodstream infection, nonfermenting Gram-negative bacilli were more frequently detected at t
25 ized arterial catheters due to nonfermenting Gram-negative bacilli were more frequently observed at t
26 ved among pneumonias caused by nonfermenting gram-negative bacilli, but not Enterobacteriaceae or oth
27 The MICs of CFDC were determined for 610 Gram-negative bacilli, including 302 multinational Enter
28 eptibility testing using a collection of 297 Gram-negative bacilli, including members of the order En
31 ted using a cohort of contemporary, clinical Gram-negative bacillus isolates from 3 U.S. academic med
32 ens is a red pigment (prodigiosin)-producing Gram-negative bacillus that is naturally found in soil a
33 h Staphylococcus aureus bacteremia (SAB) and gram-negative bacteremia (GNB) to compare the characteri
34 cal trial including adults hospitalized with gram-negative bacteremia conducted in 3 Swiss tertiary c
36 acterial assays with wild-type and resistant Gram negative bacteria carrying either single or multipl
39 enterococci (P = .008), multidrug-resistant gram-negative bacteria (P = .016), or quinolone-resistan
41 zed filters quickly killed Gram-positive and Gram-negative bacteria aerosols in vitro, with CFU reduc
43 ificities, moderately high sensitivities for Gram-negative bacteria and Candida species, and elevated
46 S) are essential envelope components in many Gram-negative bacteria and provide intrinsic resistance
48 eptation is critical to faithful division in Gram-negative bacteria and vital to the barrier function
51 rimeric porins in the outer membrane (OM) of Gram-negative bacteria are the conduits by which nutrien
52 A key group of quorum sensing molecules in Gram-negative bacteria are the N-acylhomoserine lactones
53 investigated the binding of CTRP6 to various Gram-negative bacteria as well as PRMs and enzymes of th
54 that neutrophils recognize Gram-positive and Gram-negative bacteria by means of multiple phagosomal T
66 Outer membrane vesicles (OMVs) produced by Gram-negative bacteria have roles in cell-to-cell signal
67 ogically efficacious therapy for fermenting, gram-negative bacteria in blood culture(s) if they were
70 ority pathogens listed by the WHO, including Gram-negative bacteria in the critical priority category
72 g proteins (GBPs) assemble on the surface of Gram-negative bacteria into polyvalent signaling platfor
82 l envelope stability(4); however, most other Gram-negative bacteria lack Lpp so it has been assumed t
84 biotic enhancer properties against resistant Gram-negative bacteria of four antibiotics belonging to
85 his breaks the dogma that beta-lactams enter Gram-negative bacteria only by passive diffusion through
86 Gram stain for delineating gram-positive or gram-negative bacteria or fungi within corneal scrapes.
88 y; however, there is little knowledge on how Gram-negative bacteria release their OMs into their envi
90 hronic inflammatory disease characterized by Gram-negative bacteria responsible for the degradation o
92 ow-derived macrophages (BMDMs) infected with Gram-negative bacteria such as Citrobacter rodentium, Es
93 outer membrane (OM) is a defining feature of Gram-negative bacteria that serves as a permeability bar
94 eview will focus on representative SLPs that gram-negative bacteria use to overcome host innate immun
95 nal domination (relative abundance >=30%) by gram-negative bacteria was used as predictor of gram-neg
97 aride (LPS) resides in the outer membrane of Gram-negative bacteria where it is responsible for barri
98 re important cell surface polysaccharides in gram-negative bacteria where they extend core lipopolysa
99 is an uncharacterized protein ubiquitous in Gram-negative bacteria whose gene frequently occurs in c
100 ns is the decoration of the outer surface of gram-negative bacteria with proteins tethered to the out
102 gram-positive bacteria), TLR4 (receptor for gram-negative bacteria), or distilled water (control) an
103 not included): Gram-positive bacteria, 58%; Gram-negative bacteria, 78%; and Candida species, 83%.
104 the beta-barrel assembly machinery (BAM) in Gram-negative bacteria, and by the sorting and assembly
105 OMP folding is an essential process in all Gram-negative bacteria, and considering the looming cris
107 positive bacteria and increased abundance of gram-negative bacteria, compared with mice given only wa
108 (LPS), a component of the outer membrane of gram-negative bacteria, disrupts the alveolar-capillary
110 with efficacy against both gram-positive and gram-negative bacteria, has the potential to enhance tre
111 prevalent cause of antibiotic resistance in Gram-negative bacteria, i.e., the deactivation of the mo
112 S in vitro and inhibit the growth of diverse Gram-negative bacteria, including polymyxin-resistant st
113 tibacterial agents with activity against MDR Gram-negative bacteria, including WHO priority pathogens
114 (LPS), an inflammatory stimulus derived from gram-negative bacteria, is present in the normal GI trac
115 the major component of the outer membrane of gram-negative bacteria, lipopolysaccharide (LPS), binds
118 ay of isoprenoid synthesis, is essential for Gram-negative bacteria, mycobacteria and apicomplexans(2
119 mediated by lipid A aminoarabinosylation in Gram-negative bacteria, namely, ArnT (undecaprenyl phosp
126 nhances combinatorial antigenic diversity in Gram-negative bacteria, while reducing associated fitnes
127 ctivity against the tested Gram-positive and Gram-negative bacteria, with a large zone of inhibition
128 uring LPS transfection; however, its role in Gram-negative bacteria-mediated NLRP3 inflammasome activ
161 e scored as bacteria/fungi/none (BAC One) or gram-negative bacteria/none (BAC Two) and compared to Gr
162 trum of activity against multidrug-resistant Gram-negative bacteria; however, breakpoints have been e
163 ion and penetration of the Gram-positive and Gram-negative bacterial cell envelope, but do not ruptur
165 is of intact proteins from Gram-positive and Gram-negative bacterial colonies sampled directly on sol
166 antimicrobial resistance phenotypes, during Gram-negative bacterial infection and will advance our u
168 provides critical hints for host response to Gram-negative bacterial infections and development of di
171 tment of a wide range of multidrug resistant Gram-negative bacterial infections, by both intravenous
176 rtunistic and frequently multidrug-resistant Gram-negative bacterial pathogen that primarily infects
177 CTX-M beta-lactamases are widespread in Gram-negative bacterial pathogens and provide resistance
179 ross prokaryotes, and in particular, several Gram-negative bacterial pathogens including Neisseria me
183 crobial activities against gram-positive and gram-negative bacterial pathogens, the avian protozoan E
185 ated the effect of maternal quinolone use on gram-negative bacterial resistance to quinolones in thei
186 richia coli epitomizes these obstacles: this gram-negative bacterial species is the most prevalent ag
187 erophore cephalosporin with activity against Gram-negative bacterial species that are resistant to ca
189 oped a method to directly detect and map the Gram-negative bacterial virulence factor lipid A derived
190 d aggregate lipopolysaccharide (LPS) and the Gram-negative bacterium Escherichia coli However, the ph
191 isine A showed moderate activity against the Gram-negative bacterium Escherichia coli, but no further
194 inosa IMPORTANCE Pseudomonas aeruginosa is a Gram-negative bacterium frequently isolated from infecte
197 five bacterial diguanylate cyclases from the Gram-negative bacterium Salmonella Enteritidis, identify
200 ica serovar Typhimurium (S Typhimurium) is a Gram-negative bacterium that induces cell death of macro
204 m-negative bacteria was used as predictor of gram-negative bloodstream infection using Cox proportion
206 e question "Does transitioning patients with gram-negative bloodstream infections from intravenous to
208 ntestinal microbiota is connected to risk of gram-negative bloodstream infections, expanding on our p
209 how RDTs influence antibiotic management for Gram-negative BSIs and whether RDT results are acted on
211 t only in Gram-positive bacteria but also in Gram-negative C. jejuni, advancing our knowledge of the
212 y known requirements for PIC targeting are a Gram-negative cell envelope and a unique cell surface an
213 We use our findings to propose a model of Gram-negative cell envelope stabilization that includes
215 high level in E. coli, is effective against Gram-negative clinical isolates, and has efficacy in mou
216 e treated empirically without broad-spectrum Gram-negative coverage, with clinical cure in 69.7%.
219 he rod-shaped cells of Myxococcus xanthus, a Gram-negative deltaproteobacterium, differentiate to env
220 causing the initial bacteremia), restarting gram-negative-directed antibiotic therapy due to clinica
222 o inhibit both gram-positive (S. aureus) and gram-negative (E. coli) bacteria on solid and porous sur
223 This study investigated the inactivation of Gram-negative Escherichia coli (E. coli) and Gram-positi
224 vironment of two live bacterial strains: the Gram-negative Escherichia coli and the Gram-positive Bac
225 lied for Gram-positive Bacillus subtilis and Gram-negative Escherichia coli as model organisms to mon
226 a bacterial lysate consisting of heat-killed Gram-negative Escherichia coli Symbio and Gram-positive
227 ed Gram-positive (Staphylococcus aureus) and Gram-negative (Escherichia coli) bacterial pathogens as
228 or Gram-positive (Enterococcus faecalis) and Gram-negative (Escherichia coli) reference strains and w
230 ctivity against a panel of gram-positive and gram-negative ESKAPE pathogens, and antibiofilm activity
232 assay measures IL-6 and TNF-alpha proteins, gram-negative (GN) and gram-positive (GP) bacterial DNA,
235 ures yielded no growth, no Staphylococcus or gram-negative growth was found for patients in group 2,
236 actam is an appropriate treatment option for gram-negative HABP/VABP, including in critically ill, hi
238 Cases were defined as 3GC-R-BSI or 3GC-R Gram-negative infection (3GC-R-GNI) (analysis 2), all ot
240 allo-HCT subjects were studied (7.5% develop gram-negative infection), with 4,768 fecal samples for a
241 listin) for treatment of multidrug-resistant Gram-negative infections, many clinical laboratories are
242 oglycoside antibiotics are effective against Gram-negative infections, these drugs often cause irreve
247 omplex, which parallel recent studies in the Gram-negative intestinal pathogen Campylobacter jejuni.
249 anism of resistance among colistin-resistant Gram-negative isolates and to detect PMCR for infection
251 diversity and ability to form biofilms, this Gram-negative nonfermenting bacterium can persist in the
253 control of Pseudomonas aeruginosa, a motile Gram-negative, opportunistic bacterial pathogen which fr
254 e or monoderm) and those with two membranes (Gram-negative or diderm) is a fundamental open question
256 re strongly associated with lower numbers of Gram-negative organisms at indoor sites (p < 0.0001).
257 athogens and mixed infections with yeast and Gram-negative organisms from the same positive blood cul
258 he methods of surface charge modulation that Gram-negative organisms may adopt for antibiotic resista
259 engineered to attach specifically to several Gram-negative organisms, including the human pathogens E
262 -DG) were assessed against Gram-positive and Gram-negative pathogenic and food spoilage bacteria, bot
263 system (T3SS), which is mainly expressed in Gram-negative pathogens and is essential for bacterial i
265 h activity against multidrug-resistant (MDR) Gram-negative pathogens as the pipeline of antibiotics i
269 s, a Gram-positive bacterium, BCV rupture by Gram-negative pathogens such as Shigella flexneri or Sal
271 ibacterial activity across Gram-positive and Gram-negative pathogens with N-linked 1,2,4-triazoles su
272 re, we detected LPS-derived lipid A from the Gram-negative pathogens, Escherichia coli (Ec, m/z 1797)
274 potent activity against multidrug-resistant gram-negative pathogens, such as carbapenem-resistant Ac
275 Given that ompA is highly conserved among Gram-negative pathogens, these studies not only provide
282 pecies spanning different classes within the Gram-negative phylum Proteobacteria: Agrobacterium tumef
284 diatric institution with a low prevalence of Gram-negative resistance, the VG RDT facilitated antibio
285 ntimicrobial susceptibility testing (AST) in Gram-negative rod (GNR) bacteremia is compelling; howeve
291 ins are covalently attached to PG in several Gram-negative species, including Coxiella burnetii, Agro
292 .7%) were vancomycin-sensitive; among the 12 gram-negative strains tested, all 12 (100%) were ceftazi
295 sistance genes, and both Pan Candida and Pan Gram-Negative targets that are unique to the BCID-GP Pan
296 greement and NPA for the Pan Candida and Pan Gram-Negative targets were 92.4% and 95.7% for the forme
299 As 80% of prostatitis cases are caused by Gram-negative uropathogenic Escherichia coli (UPEC) or G