ライフサイエンスコーパス: HIV Tat protein

1 iously cloned and shown to interact with the HIV Tat protein.

2 creased by treatment of cells with exogenous HIV-tat protein.

3 rming the chemotactic characteristics of the HIV-Tat protein.

4 The human immunodeficiency virus type 1 (HIV) Tat protein, a potent activator of HIV gene express

5 Treatment with HIV-tat protein activated NF-kappa B, degraded I kappa B

6 ences basal HIV gene expression and that the HIV Tat protein activates transcription independently of

7 ndothelium can be mimicked by treatment with HIV-Tat protein alone.

8 in transduction domain (PTD) embedded in the HIV TAT protein (amino acids 47-57) has been shown to su

9 Encapsulating an mRNA encoding the HIV Tat protein, an activator of HIV transcription, LNP

10 Formation of a specific complex between the HIV Tat protein and the small RNA element TAR is critica

11 f (ARM) of the human immunodeficiency virus (HIV) Tat protein and TAR RNA is essential for Tat activa

12 We found HIV-Tat protein and IL-17-expressing mononuclear cells i

13 the protein transduction domain (PTD) of the HIV/TAT protein and transduced pancreatic islets ex vivo

14 n of NF-kappa B, AP-1, JNK, and apoptosis by HIV-tat protein but has minimal or no role in activation

15 The HIV Tat protein can be endocytosed by surrounding uninfe

16 Our results thus indicate that the HIV-tat protein can activate human vascular EC to induce

17 man histiocytic lymphoma U937 cells with the HIV-tat protein causes activation of JNK and AP-1 in a t

18 se ApiCCT1 has a region of similarity to the HIV Tat protein cell-transduction domain, we tested whet

19 We discovered that HIV-Tat protein could be transported along anatomical pa

20 glutathione peroxidase, NK-lysin/granulysin, HIV Tat protein, H(2)O(2), lipid hydroperoxides, vitamin

21 nstrated that a TAT peptide derived from the HIV TAT protein has the ability to transduce peptides or

22 The human immunodeficiency virus (HIV) Tat protein has a critical role in viral transcript

23 The human immunodeficiency virus (HIV)-Tat protein has been implicated in the neuropathoge

24 duce an elongation block that is overcome by HIV Tat protein in conjunction with P-TEFb.

25 ot only further highlights the importance of HIV Tat protein in HIV/neuroAIDS, but also presents a ne

26 nd in the activation of transcription by the HIV Tat protein in human cells.

27 r these effects, we constitutively expressed HIV-Tat protein in astrocytes.

28 We report here that the HIV Tat protein is strongly immunosuppressive, both imme

29 Treatment of primary monocytes with soluble HIV-Tat protein is associated with increased monocyte me

30 HIV-tat protein, like TNF, activates a wide variety of c

31 Human immunodeficiency virus-1 tat (HIV-tat) protein, like other proinflammatory cytokines (

32 Treatment of primary monocytes with soluble HIV-Tat protein mimicked many of the properties of HIV i

33 , we demonstrated that exposure of HUVECs to HIV Tat protein resulted in induced expression of cell a

34 n or treatment with a CRMP2 peptide fused to HIV TAT protein (TAT-CBD3) blocked neuronal death follow

35 ugated to the protein transduction domain of HIV-TAT protein (TATFLAGVHL-peptide) to facilitate entry

36 l-penetrating peptide (CPP) conjugate of the HIV TAT protein that is fused to an aminoterminal sequen

37 spired by the cell invasion mechanism of the HIV TAT protein, the Pdots were formed from block copoly

38 was fused to the polybasic sequence from the HIV Tat protein to facilitate entry into cells.

39 The conjugation of peptides derived from the HIV TAT protein to membrane-impermeant molecules has gai

40 Binding of the HIV tat protein to the TAR (transactivating response reg

41 but continues to synergize normally with the HIV Tat protein to transactivate the HIV long terminal r

42 argeted by the human immunodeficiency virus (HIV) Tat protein to activate elongation of the integrate

43 t study, we have examined the ability of the HIV-Tat protein to alter the migratory and invasive beha

44 tumor-associated Ag (OVA) that contains the HIV TAT protein transduction domain (PTD) was readily en

45 RF45 56 to 76 amino acid (aa) region and the HIV Tat protein transduction domain, and this peptide ma

46 s with versions of these peptides containing HIV-Tat protein transduction and mammalian mitochondrial

47 f class IA PI3K adaptor subunit, fused to an HIV-TAT protein transduction domain (TAT-Deltap85) conce

48 on into mice of dnRas, which was fused to an HIV-TAT protein transduction domain (TAT-dnRas).

49 When fused to the HIV-TAT protein transduction domain and delivered as a p

50 ibitors of transcriptional activation by the HIV Tat protein, we used a combination of in vitro and i

51 Lipopolysaccharide (LPS) and the neurotoxic HIV Tat protein, which cause dopamine neuronal toxicity

52 HIV Tat protein, which is the transactivator of transcri