ライフサイエンスコーパス: HIV infection

1 s valuable for developing a vaccine to block HIV infection.

2 the impact of ART on TB reactivation due to HIV infection.

3 ve, antiretroviral therapy is not a cure for HIV infection.

4 CCR7(+) proinflammatory AM were increased in HIV infection.

5 paucity of relevant animal models of penile HIV infection.

6 rs and nonsmokers, 23 of whom had documented HIV infection.

7 bs) can suppress viremia and protect against HIV infection.

8 opment of strategies to prevent and/or treat HIV infection.

9 condom use with clients, and depression and HIV infection.

10 at is referred to as the latent reservoir of HIV infection.

11 y CD4 T cells with active or drug-suppressed HIV infection.

12 associated with increased susceptibility to HIV infection.

13 pha(4)beta(7) likely impacts early events in HIV infection.

14 btype B-infected adults treated during early HIV infection.

15 reased female susceptibility to intrauterine HIV infection.

16 nce clusters, and to analyze multiplicity of HIV infection.

17 nd its role in CD4 T-cell homeostasis during HIV infection.

18 n in the two most important target cells for HIV infection.

19 wing infection, as well as in the absence of HIV infection.

20 ersal, must be developed to clear persistent HIV infection.

21 ocervix, which could confer a higher risk of HIV infection.

22 ecognized host signaling pathway involved in HIV infection.

23 ID) are at a disproportionately high risk of HIV infection.

24 during ART in three in vivo animal models of HIV infection.

25 transplantation (LT) recipients with/without HIV infection.

26 and may modulate cellular pathways linked to HIV infection.

27 raction occurring during the early stages of HIV infection.

28 disorders (HANDs) are a frequent outcome of HIV infection.

29 teractions and are substantially affected by HIV infection.

30 y CD4 T cells with active or drug-suppressed HIV infection.

31 and their molecular drivers, and apply it to HIV infection.

32 d in response to BV, as a potential cause of HIV infection.

33 ed cardiovascular risk in people living with HIV infection.

34 elease of platelet-derived MVs occurs during HIV infection.

35 to be a potential source of inflammation in HIV infection.

36 duct with the potential to effectively treat HIV infection.

37 he need for early diagnosis and treatment of HIV infection.

38 T is initiated during the earliest phases of HIV infection.

39 are recommended for first-line treatment of HIV-infection.

40 ary analyses were conducted among those with HIV-infection.

41 s are at the forefront of new treatments for HIV infections.

42 scale in the US to accelerate reductions in HIV infections.

43 l have the greatest impact on decreasing new HIV infections.

44 microbial dysbiosis observed during SIV and HIV infections.

45 the context of human immunodeficiency virus (HIV) infection.

46 the context of human immunodeficiency virus (HIV) infection.

47 ute, and early human immunodeficiency virus (HIV) infection.

48 th and without human immunodeficiency virus (HIV) infection.

49 prevention of human immunodeficiency virus (HIV) infection.

50 oid cells, expand during chronic viral (HCV, HIV) infections.

51 d PrEP with individuals newly diagnosed with HIV infection, 2) identified the specialties of practiti

52 HIV infection (24.4%, 74/303) was not associated with ot

53 d 4.9% (95% CI 3.6-6.4) were attributable to HIV infection (28 000 new cases, 20 000-36 000).

54 Among participants with HIV infection, 36/108 (33%) had incidental findings comp

55 .1; 95% confidence interval, 72.7-431.5) and HIV infection (4.34; 1.88-10.05).

56 was identified in 95% of patients, including HIV infection (45%), solid organ transplant (26%), and c

57 cebo recipients) and 140 pregnant women with HIV infection (72 IIV3 and 68 placebo recipients) were i

58 dy included 185 women (128 with longstanding HIV infection, 88% under antiretroviral therapy; and 57

59 ers; P < .001) and had fewer newly diagnosed HIV infections (9 vs 26 among nonusers; P = .014).

60 Patients with HIV infection account for only 1% of LTs in United State

61 HIV infection affects up to 30% of children presenting w

62 antly improved with cure but not better than HIV infection alone, which strong suggests that cognitiv

63 Altogether, these findings suggest that HIV infection, along with cigarette smoke, favors a proi

64 ects immunodepressed patients with stage III HIV infection, although in recent years it has also been

65 connections to northeastern Massachusetts or HIV infections among other persons named as partners of

66 erage of 2.7% among PWID), the number of new HIV infections among PWID in Ukraine over the next 10 ye

67 utbreak of new human immunodeficiency virus (HIV) infections among persons who inject drugs (PWID).

68 n shown to be beneficial in the treatment of HIV infections, among others.

69 g 47,592 patients, 122 (0.26%) had confirmed HIV infection and 112/122 (91.8%) had a record of antire

70 The parent study included 108 adults with HIV infection and 125 demographically-matched uninfected

71 ed and included in analyses; 36 had in-utero HIV infection and 389 (89%) were born at term.

72 status or ADI with age suggests that chronic HIV infection and ADI have independent effects on brain

73 Inclusion criteria were confirmed HIV infection and age > 18 years.

74 least 18 years, with untreated but confirmed HIV infection and an estimated gestation of at least 28

75 Maternal HIV infection and antiretroviral treatment (ART) have be

76 assess population prevalence of undiagnosed HIV infection and ART coverage, and progress towards 90-

77 view of the genetic dependencies underlying HIV infection and can be used to identify drug targets a

78 fy studies analysing the association between HIV infection and cervical cancer.

79 ndings were common in both participants with HIV infection and controls, at higher rates than previou

80 ere used to estimate the association between HIV infection and COVID-19 death; they were initially ad

81 usly diagnosed partners of people with a new HIV infection and examine their HIV care status and vira

82 0 years) who were considered at low risk for HIV infection and had not received any vaccines in the 1

83 ls aged 20-40 years who were at low risk for HIV infection and in good health.

84 n resistance were positively associated with HIV infection and increased mortality.

85 although the gut microbiome is influenced by HIV infection and may contribute to altered immunity, th

86 evels were elevated during early and chronic HIV infection and persisted despite long-term antiretrov

87 C frequencies may be a link between maternal HIV infection and preterm birth.

88 opathy is a common neurologic comorbidity of HIV infection and prevails in the post-antiretroviral th

89 HIV-1 Vpr is necessary for maximal HIV infection and spread in macrophages.

90 Study interventions included support for HIV infection and substance use treatment.

91 rotective laws are associated with prevalent HIV infection and that stigmas and sex work laws may syn

92 vealed a correlation between reduced risk of HIV infection and the level of nonneutralizing-antibody

93 of frailty with both outcomes, adjusting for HIV infection and traditional risk factors.

94 pendent studies, so that greater insights on HIV infection and treatment dynamics may be gained.

95 Adults (>=18 years) with HIV infection and undetectable viral load (<40 copies pe

96 ran Africa are disproportionally affected by HIV infection and unintended pregnancies.

97 tiretroviral therapy (ART) during very early HIV infection and who interrupted their ART as part of a

98 hest HIV burden would account for 56% of new HIV infections and 49% of deaths prevented over 10 years

99 prove the cost-effectiveness, averting 78.0% HIV infections and add 29,242 QALYs at a cost of $51,597

100 plementing PrEP in all MSM would avert 75.2% HIV infections and facilitate a gain of 37,372 QALYs at

101 sk to estimate the effect of OAT scale-up on HIV infections and mortality over a 10-year horizon.

102 % CI 3134-5243) and 10 864 (7787-13 038) new HIV infections and reduce deaths by 7096 (95% CI 5078-91

103 Human immunodeficiency virus (HIV) infection and antiretroviral therapy (ART) are asso

104 ivation during human immunodeficiency virus (HIV) infection and is usually assessed by measuring plas

105 re at risk for human immunodeficiency virus (HIV) infection and unintended pregnancies.

106 with perinatal human immunodeficiency virus (HIV) infection and with low bone mineral density (BMD) m

107 of new molecules promising for treatment of HIV-infection and HIV-associated disorders remains an im

108 imating of potential agents for treatment of HIV-infection and its comorbidities, we have created a f

109 gal colonization in the gut increases during HIV-infection and people living with HIV (PLWH) have inc

110 exposure on the inflammation associated with HIV infection, and demonstrate that these two insults ex

111 culating CD4 T cells from people living with HIV infection, and investigate potential mechanisms link

112 nrolled 323 women, of whom 234 had perinatal HIV infection, and reported age at sexual debut and hist

113 ntrol mechanisms that can be dysregulated in HIV infection, and the use of methamphetamine can furthe

114 al environment that influences the course of HIV infection, and we investigated whether pre-existing

115 ansplantation, Human immunodeficiency virus (HIV) infection, and elevated serum iron.

116 virus (SIV) or human immunodeficiency virus (HIV) infection, and some recovery may occur within weeks

117 ugs; men who have sex with men; persons with HIV infection; and sex partners, needle-sharing contacts

118 accounts for most of the 180 000 new infant HIV infections annually.

119 c infection, approaches to eradicate or cure HIV infection are desired.

120 aking ART and persons taking PrEP to prevent HIV infection are donating blood.

121 d pre-exposure prophylaxis (PrEP) to prevent HIV infection are effective tools to help end the HIV ep

122 HIV cure strategies.IMPORTANCE Persons with HIV infection are frequently coinfected with chronic her

123 past decades, human immunodeficiency virus (HIV) infections are still responsible for nearly 1 milli

124 he greatest obstacle to obtaining a cure for HIV infection, as these cells can persist despite decade

125 Chronic HIV infection associates with reduced brain frontal cort

126 d gp140 with high affinity and inhibition of HIV infection at nanomolar concentrations without mitoge

127 om 2012-2019, between 2434 and 3476 GBM with HIV-infection attended our primary-care sites annually p

128 With HIV infection, B cell differentiation and regulatory mar

129 loration of novel therapeutic strategies for HIV infection based on genome editing of CCR5.

130 Antiretroviral therapy (ART) cannot cure HIV infection because of a persistent reservoir of laten

131 treatment (ART), and the association between HIV infection, birth outcomes and maternal characteristi

132 ignificantly differ in age, sex, presence of HIV infection, body mass index, or hemoglobin level (P >

133 xposure and incomplete treatment of maternal HIV infection, but not early CMV infection.

134 roportion of MSM in Korea would prevent more HIV infections, but at an increasing cost per QALY gaine

135 Infants of HIV-positive mothers can acquire HIV infection by various routes, but even in the absence

136 e of patients on ART was projected to reduce HIV infections by 4.5% (90% model variability 1.6 to 7.6

137 Our results suggest a strategy to eradicate HIV infections by selectively eliminating host cells cap

138 g African children with perinatally-acquired HIV infection (C-PHIV), despite combination antiretrovir

139 HIV infection can be effectively treated by lifelong adm

140 Human immunodeficiency virus (HIV) infection causes impairment of the gastrointestinal

141 ding economic analysis, we estimated averted HIV infections, changes in HIV prevalence, discounted co

142 recruited from the Copenhagen Comorbidity in HIV Infection (COCOMO) Study and matched 1:1 on age and

143 articipants of the Copenhagen Comorbidity in HIV Infection (COCOMO) study.

144 MPORTANCE Human and animal studies show that HIV infection, combined with the long-term use of psycho

145 LBT has higher sensitivity for acute HIV infection compared to RT but LBT is not point of car

146 lations, for the treatment and prevention of HIV infection continue to guide optimal practices.

147 tudies across reviews to quantify effects on HIV infections, continuum of HIV care, sexual risk, and

148 Prevalence of undiagnosed HIV infection decreased from 4.7% to 2.0% (prevalence ra

149 Drug bioavailability decreased by 27% with HIV infection, decreased by 28% with fasting, and increa

150 ortance of inflammatory cytokines in mucosal HIV infection, demonstrating the likely critical role th

151 Cases were defined as HIV infections diagnosed during 2015-2018 among people w

152 HIV infection, diarrhea, pneumonia, shock, lack of appet

153 HIV infection did not affect the capacity of these marke

154 cinations or infections that occurred before HIV infection did not recover after immune reconstitutio

155 In conclusion, HIV infection does not appear to have a significant impa

156 HIV infection drives pathologic changes in the dorsal ro

157 d be no more than one period at high risk of HIV infection during the follow-up period when not takin

158 Seven partners acquired HIV infection during the study (seroconverters).

159 RT) within 1 year of their estimated date of HIV infection (EDI).

160 Currently, the incidence of HIV infection exceeds the death rate from HIV, and as a

161 hat TZM-gfp cells are equally susceptible to HIV infection, exhibit minimal background signal, and ca

162 ferences in adverse outcomes associated with HIV infection for hospitalized COVID-19 patients compare

163 e tools for systemic clearance of persistent HIV infection-greatly increases opportunities for HIV er

164 light of the increasing global burden of new HIV infections, growing financial requirements, and shif

165 of pre-existing Mtb infection on subsequent HIV infection has not been fully explored.

166 uring pregnancy, women living with perinatal HIV infection have a high risk of post-partum viraemia.

167 ir must be sought.IMPORTANCE Efforts to cure HIV infection have focused primarily on the elimination

168 le living with human immunodeficiency virus (HIV) infection have higher risk for chronic kidney disea

169 HIV infection (HR: 4.32; 95% CI: 2.31, 8.08), weight-for

170 Age, HIV infection, illicit drug use, and CNS opportunistic i

171 g the inflammatory environment; however, how HIV infection impacts AM phenotype and function is not w

172 Whether human immunodeficiency virus (HIV) infection impacts gut microbial alpha-diversity is

173 ific Env Abs associated with reduced risk of HIV infection.IMPORTANCE The aim of this work was to des

174 omeric DDR and CD4 T-cell homeostasis during HIV infection.IMPORTANCE The hallmark of HIV infection i

175 bial translocation within the context of SIV/HIV infection.IMPORTANCE There is a slow yet significant

176 te bNAbs for the treatment and prevention of HIV infection in Africa.

177 Overall, we demonstrate that HIV infection in Cameroon is associated with deficits in

178 or, coupled with findings of protection from HIV infection in individuals lacking CCR5, led to the ex

179 degradation of a factor, REAF, that impedes HIV infection in macrophages.IMPORTANCE For at least 30

180 hat knockout of CNOT1, 10, and 11 suppressed HIV infection in primary T cells by upregulating innate

181 it minimal background signal, and can report HIV infection in rare cells from a bulk population of ex

182 deterioration of CD8 T-cell responses during HIV infection in the absence of antiretroviral treatment

183 These genes may contribute to latent HIV infection in the gut and may serve as new targets fo

184 vital sign measurements, and at low risk of HIV infection in the opinion of study staff, who applied

185 ancy history for women living with perinatal HIV infection in the Pediatric HIV/AIDS Cohort Study-AMP

186 activated (p = 0.01) and more susceptible to HIV infection in vitro (p = 0.03).

187 of TFIIH, and concurrently suppresses acute HIV infection in vitro Here we investigated SP as a poss

188 compare the number of averted (or prevented) HIV infections in each of the two trial groups, calculat

189 Of new HIV infections in the US, 20% occur among young men who

190 ounts for most human immunodeficiency virus (HIV) infection in children, and treatments for newborns

191 gonorrhea and human immunodeficiency virus (HIV) infection in men who have sex with men who were not

192 y those that would prevent the most incident HIV infections, including low school attendance, intimat

193 ns can help reduce prevalence of undiagnosed HIV infection, increase ART use among all people living

194 alence < 25%, adjusted odds ratios (AORs) of HIV infection increased from 2.8 (95% CI 1.2-6.3) in tho

195 le for insufficient immune reconstitution in HIV infection independently of the gut microbiota.

196 ith late-stage human immunodeficiency virus (HIV) infection initiating antiretroviral therapy, screen

197 ing HIV infection.IMPORTANCE The hallmark of HIV infection is a gradual depletion of CD4 T cells, wit

198 While it is known that uncontrolled HIV infection is a major risk factor for the development

199 While HIV infection is associated with a localized effect on s

200 Acute HIV infection is associated with a rapid depletion of al

201 ely dated pregnancies, we show that maternal HIV infection is associated with reduced levels of all t

202 Whether HIV infection is associated with risk of death due to CO

203 Acute HIV infection is characterized by rapid viral seeding of

204 ding the earliest immune responses following HIV infection is critical to inform future vaccines and

205 These findings suggest that maternal HIV infection is independently associated with differenc

206 impact host immune responses associated with HIV infection is still unknown.

207 A key manifestation of HIV infection is the loss of CD4 T cells, which are cruc

208 Latent HIV infection is the main barrier to cure, and most HIV-

209 The major obstacle to a cure for HIV infection is the persistence of replication-competen

210 erapy (CPT) in human immunodeficiency virus (HIV) infection is a World Health Organization-recommende

211 that untreated human immunodeficiency virus (HIV) infection is associated with a reduced incidence of

212 d with chronic human immunodeficiency virus (HIV) infection is associated with a smaller HIV reservoi

213 Human immunodeficiency virus (HIV) infection is characterized by a massive loss of CD4

214 HIV-infection is associated with increased mortality dur

215 dle-income country with a high prevalence of HIV infection, L. monocytogenes caused disproportionate

216 n the field of HIV and acquired knowledge on HIV infection, latency, and host response.

217 eases, such as human immunodeficiency virus (HIV) infection, malaria and influenza, effective vaccina

218 tion strategies, future therapies that clear HIV infection may relieve society of the affliction of t

219 HIV-infection may increase the risk of RSV illness among

220 e mechanism limiting viral spread.IMPORTANCE HIV infection modulates the surface expression of Tim-3,

221 (n = 32, 20.5%), cancer (n = 15, 9.6%), and HIV infection (n = 3, 1.9%).

222 treatments of human immunodeficiency virus (HIV) infections; nevertheless, recent developments in th

223 Persistent HIV infection of long-lived resting CD4 T cells, despite

224 Candidates with well controlled HIV infection on ART, no active opportunistic infections

225 , we reviewed medical records of people with HIV infection on cART in a referral AIDS center in Salva

226 of this study was to evaluate the impact of HIV infection on human AM and to compare the effect of s

227 We evaluated the impact of maternal HIV infection on the burden of RSV among mothers and the

228 im of this study was to assess the impact of HIV infection on the risk of developing hepatocellular c

229 ur findings suggest that, regardless of age, HIV infection or exposure, low CD4 levels persistently a

230 Elevated HERV expression, mediated by HIV infection or other stressors, can have various HERV-

231 utcomes under quasi-experiments (eg, reduced HIV infection [OR = 0.42, CI = 0.27-0.63]; favorable con

232 We found no new HIV infections over 136 person-years of follow-up.

233 Without PrEP, the model predicted 920 new HIV infections over a decade, or an average incidence of

234 ith increasing age in both participants with HIV infection (p = 0.013) and controls (p = 0.022).

235 of primary HIV infection (PHI) and/or recent HIV infection (patients with CD4 cell count >=500/mm3 at

236 d the potential association between maternal HIV infection, peripheral ILC frequencies and preterm bi

237 tudy to describe the epidemiology of primary HIV infection (PHI) and/or recent HIV infection (patient

238 60 individuals who began ART during primary HIV infection (PHI) investigates which pre- and postther

239 Adolescents with perinatally-acquired HIV infection (PHIVA) should be a focus for treatment fa

240 le living with human immunodeficiency virus (HIV) infection (PLWH).

241 HIV infection positively modified the association betwee

242 Compared to individuals with newly diagnosed HIV infection, PrEP patients were more likely to be non-

243 HCV incidence and prevalence among GBM with HIV-infection provides proof-of-concept for HCV micro-el

244 hy (CT) findings in well-treated people with HIV infection (PWH) remain poorly characterized.

245 People with human immunodeficiency virus (HIV) infection (PWH) have an increased risk of cardiovas

246 Main outcomes included averted HIV infections, quality-adjusted life-years (QALYs), tot

247 Neonates without confirmed in-utero HIV infection received nevirapine for a median of 13 day

248 Participants with HIV infection receiving combination antiretroviral thera

249 ore robust type 1 interferon response during HIV infection relative to men, contributing to lower ini

250 icant progress, several questions related to HIV infection remain to be addressed.

251 individuals with active and virus-suppressed HIV infection remains unclear.

252 Overcoming the global health threat of HIV infection requires continuous pipelines of novel dru

253 nclear whether human immunodeficiency virus (HIV) infection results in permanent loss of T-cell memor

254 for HIV seroconversion, the variable risk of HIV infection (seasons of risk) estimated with routine r

255 B from LTBI and EPTB from PTB, regardless of HIV infection status.

256 The Copenhagen Co-Morbidity in HIV Infection study included 453 participants, and the C

257 aphic distance between genetically clustered HIV infections, suggesting that individuals mainly use t

258 e genital tract (FGT) inflammation increases HIV infection susceptibility.

259 on and mitochondrial densities were lower in HIV infection than in controls.

260 icantly higher in the blood of subjects with HIV infection than in that of healthy controls and great

261 Scott County had the potential to avert more HIV infections than reactive implementation after the de

262 udies uncover a link of FOXO1, ER stress and HIV infection that could be therapeutically exploited to

263 uptick in systemic inflammation secondary to HIV infection that has long-term consequences for the in

264 ral markers of human immunodeficiency virus (HIV) infection that increase before viral rebound during

265 iduals and that is a major barrier to curing HIV infection, the in vivo proliferation of latently inf

266 re features of human immunodeficiency virus (HIV) infection, their interplay is unclear.

267 provided many insights into the dynamics of HIV infection, there is still a lack of accessible tools

268 n (MTOR) has cellular effects that may alter HIV infection through other mechanisms.

269 this study, we employed a cellular model of HIV infection to characterize the mechanisms underlying

270 this study, we employed a cellular model of HIV infection to characterize the mechanisms underlying

271 ty participants who started ART during acute HIV infection underwent CNS assessments across four ATI

272 In chronic HIV infection, virus-specific cytotoxic CD8 T cells show

273 t survival in LT recipients with and without HIV infection was 64.4% and 77.3%, respectively (P < 0.0

274 HIV infection was associated with age and ethnicity.

275 HIV infection was independently associated with 1.82 (95

276 In a multivariate analysis, HIV infection was independently associated with diverse

277 HIV infection was independently associated with intersti

278 No incident HIV infection was reported among women on PrEP.

279 Perinatal HIV infection was significantly associated with communit

280 e number of newly diagnosed individuals with HIV infection, we found MSAs with relatively low uptake

281 associated with reduced frequency of latent HIV infection, we hypothesized that women on ART would h

282 To assess the risk of BCG vaccination in HIV infection, we randomly assigned newborn rhesus macaq

283 People with a primary care record for HIV infection were compared with people without HIV.

284 related to survival among LT recipients with HIV infection were determined.

285 MSM diagnosed with acute and early HIV infection were recruited from the Primary Infection

286 Three infant HIV infections were detected, all in the dolutegravir gr

287 ndow of opportunity for preventing perinatal HIV infection when treatment is delayed.

288 obes is important to consider, especially in HIV infection where gut-intestinal barrier dysfunction c

289 The primary efficacy outcome was incident HIV infection, which was assessed when all participants

290 omes among young women living with perinatal HIV infection who are now ageing into adulthood and beco

291 Among severely immunosuppressed adults with HIV infection who had not previously received ART, syste

292 th, born to women with presumed or confirmed HIV infection who had not received antiretrovirals durin

293 findings found on brain MRI in patients with HIV infection, who may be at risk for HIV-Associated Neu

294 Curing HIV infection will require the elimination of a reservoi

295 n and cellular turnover due to long-standing HIV infection with delayed cART initiation.

296 Treatment of HIV infection with either antiretroviral (ARV) therapy o

297 here have been attitudinal changes regarding HIV infection with resultant increases in sexual contact

298 ed to integrate treatment for IDU-associated HIV infections with treatment for drug use disorders.

299 , a well-accepted non-human primate model of HIV infection, with adeno-associated virus 9 (AAV9)-CRIS

300 al genera were identified as associated with HIV infection, with higher abundances of Ruminococcus an