ライフサイエンスコーパス: HMGB protein

1 alized by comparison of solved structures of HMGB proteins.

2 ecific and non-sequence-specific families of HMGB proteins.

3 tural factors such as high mobility group B (HMGB) proteins.

4 ctural proteins such as high mobility group (HMGB) proteins.

5 ively identified as high mobility group box (HMGB) proteins 1 and 3, and a 70-kDa band was identified

6 e chromatin protein high mobility group box (HMGB) protein 2 is restricted to the SZ in articular car

7 e chromatin protein high-mobility group box (HMGB) protein 2 is uniquely expressed in the superficial

8 Eukaryotic High-Mobility Group B (HMGB) proteins alter DNA elasticity while facilitating t

9 E. coli cells to explore the extent to which HMGB proteins and derivatives can complement a DNA loopi

10 nds are only moderately discriminated by the HMGB proteins and TBP, but the recognition of dsTG*G*A i

11 The differential expression levels of HMGB proteins and/or mRNAs and their implications in can

12 HMO1 is one of 10 Saccharomyces cerevisiae HMGB proteins, and it is required for normal growth and

13 HMGB proteins are abundant non-histone components of euk

14 High mobility group box (HMGB) proteins are architectural proteins whose HMG DNA

15 High mobility group box (HMGB) proteins belong to the high mobility group (HMG) s

16 While all of the HMGB proteins bend DNA to preferred angles, Nhp6A promot

17 HMGB proteins bind preferentially to DNA that is bent or

18 High-mobility group B (HMGB) proteins bind duplex DNA without sequence specific

19 two eukaryotic high-mobility group class B (HMGB) proteins binding to approximately 200-bp DNA molec

20 ed proteins, of which high-mobility group B (HMGB) proteins consistently cofractionated by cation-exc

21 Surprisingly, HMGB proteins constrain DNA winding, and this torsional

22 Group B (HMGB) proteins contain HMG box domains known to bind to

23 High mobility group B (HMGB) proteins contain two HMG box domains known to bind

24 es for nucleosomes over linker DNA, and both HMGB proteins destabilize and unwind DNA from the H2A-H2

25 Therefore, the mechanism by which HMGB proteins enhance the flexibility of DNA must differ

26 ic recognition of DNA kinks, we propose that HMGB proteins facilitate RAG1/2-RSS interactions by reco

27 There is evidence that HMGB proteins facilitate, while linker histones inhibit

28 ein is an essential high mobility group box (HMGB) protein facilitating Pol I transcription in T. bru

29 e (HU) and eukaryotic high-mobility group B (HMGB) proteins fall into this category.

30 HMGB4, a new member of the mammalian HMGB protein family expressed preferentially in the test

31 HMGB1, the most studied member of the HMGB protein family, has pleiotropic roles in cells incl

32 accharomyces cerevisiae which belongs to the HMGB protein family.

33 The single-domain HMGB protein from Saccharomyces cerevisiae, Nhp6A, effic

34 Moreover, the HMGB proteins have been identified in regulating DNA dam

35 HMGB proteins have been implicated in the pathogenesis a

36 ows that linker histones and the chromosomal HMGB proteins, HMG-D and HMG-Z, have opposite effects on

37 show here that the Saccharomyces cerevisiae HMGB protein HMO1 stabilizes chromatin as evidenced by f

38 s features with the Saccharomyces cerevisiae HMGB protein Hmo1, but it is the first architectural chr

39 Here, we discuss the functions of HMGB proteins in DNA damage processing and their potenti

40 ker histone H1 and the functionally opposite HMGB proteins is critical for higher-order chromatin str

41 logical function of DNA sequence-nonspecific HMGB proteins is obscure.

42 cterial DNA-binding protein HU and the yeast HMGB protein NHP6A display the same phenomenon of protei

43 ability of the abundant chromatin-associated HMGB protein Nhp6A from Saccharomyces cerevisiae to trav

44 Here, we show that derivatives of the yeast HMGB protein Nhp6A rescue DNA looping in E. coli lacking

45 We also show data for the yeast HMGB protein NHP6A showing a similar DNA-concentration-d

46 o a specific site to determine the effect of HMGB proteins on recognition of these lesions.

47 Our observations support a model in which HMGB proteins soften DNA through random dynamic binding

48 Our previous work suggests that the Nhp6 HMGB protein stimulates RNA polymerase II transcription

49 eriments to show that high mobility group B (HMGB) proteins strongly disrupt nucleosomes, revealing a

50 HMGB4 is a new member in the family of HMGB proteins that has been characterized in sperm cells

51 (h-mtTFA) is a dual high mobility group box (HMGB) protein that binds site-specifically to the mitoch

52 results show that HMO1 shares with mammalian HMGB proteins the ability to promote DNA association.

53 ruits the family of high mobility group box (HMGB) proteins to chromatin along with the histone chape

54 linker histones and high-mobility group box (HMGB) proteins--to DDR and their potential significance

55 ne the nature of this behavior for different HMGB proteins, we used atomic force microscopy to quanti