ライフサイエンスコーパス: ICF

1 ICF (Immunodeficiency, Centromeric instability and Facia

2 ICF (immunodeficiency, centromeric region instability an

3 ICF and MT showed distinct signatures from SICI and CSP.

4 ICF experiments have recently achieved an alpha-heating

5 ICF has been localized to a 9-centimorgan region of chro

6 ICF syndrome is the only genetic disorder known to invol

7 ICF was associated with pain measured through the Visual

8 ICF-associated decreases were observed in RNAs encoding

9 ICF-specific increases in immunoglobulin (Ig) heavy cons

10 ICF-specific increases were seen in RNA for RGS1, a B-ce

11 these phenotypes were lost in the case of an ICF syndrome mutant of CDCA7 mutated in the zinc finger

12 to identify when to implement or suspend an ICF intervention would be valuable.

13 ns were also associated with discharge to an ICF (21.9% vs. 8.9%, P < 0.001).

14 associated with the risk of discharge to an ICF after abdominopelvic operations.

15 Patients discharged to an ICF after surgery had higher 30-day (4.3% vs. 0.4%), 90

16 Patients discharged to an ICF are much more likely to die within the first postope

17 s discharged home, patients discharged to an ICF had 4 times higher 1-year mortality (odds ratio = 3.

18 Of patients who died after discharge to an ICF, the majority died either at the ICF (53.7%) or on a

19 CFS was diagnosed in 41.5% (22/53) and ICF in 13.2% (7/53).

20 ms to increase the speed of TB diagnosis and ICF yield.

21 F(2)CFIOR(F) at 240 degrees C gave R(F)I and ICF(2)CF(2)COF in high yields.

22 ing the rollout and effectiveness of IPT and ICF is the limitations of existing tools to both diagnos

23 Use of the disablement-enablement model and ICF taxonomy in conjunction with outcomes across disable

24 to determine when to switch between PCF and ICF to efficiently use resources to optimize population

25 The effects exerted on SICI and ICF by four intensities (60-90% of active motor threshol

26 , although the duration of the CSP, SICI and ICF did not change.

27 rtical inhibition and facilitation (SICI and ICF) and long interval intracortical inhibition (LICI).

28 die within the first postoperative year and ICF disposition should be considered as either a marker

29 cy Centromeric Instability Facial Anomalies (ICF) 4 syndrome is a severe disease with increased morta

30 cy Centromeric Instability Facial Anomalies (ICF) 4 syndrome is caused by mutations in LSH/HELLS, a c

31 y, centromere instability, facial anomalies (ICF) syndrome cases, a rare recessive disease characteri

32 , Centromeric instability, Facial anomalies (ICF) syndrome is a chromatin disorder characterized by m

33 entromeric Instability and Facial Anomalies (ICF) syndrome is a genetically heterogeneous autosomal r

34 ntromeric instability, and facial anomalies (ICF) syndrome is a genetically heterogeneous disorder.

35 ntromeric instability, and facial anomalies (ICF) syndrome, a disease related to hypomethylation of j

36 cy-centromeric instability-facial anomalies (ICF) syndrome, a genetic disorder associated with the lo

37 entromeric instability and facial anomalies (ICF) syndrome, a genetic disorder characterized by DNA h

38 ntromeric Instability, and Facial Anomalies (ICF) syndrome, characterized by centromeric instability.

39 ntromeric instability, and facial anomalies (ICF) syndrome, function as negative regulators of 2C-lik

40 ntromeric instability, and facial anomalies (ICF) syndrome, which also results in DNA hypomethylation

41 Centromere instability and Facial anomalies (ICF) syndrome, which is associated with neurologic defic

42 centromere instability and facial anomalies (ICF) syndrome.

43 entromeric instability and facial anomalies (ICF) syndrome.

44 ntromeric instability, and facial anomalies (ICF) syndrome.

45 entromere instability, and facial anomalies (ICF) syndrome.

46 G6PD in one ICF female and SYBL1 in another ICF female provide the first examples of abnormal escape

47 The recessive autosomal disorder known as ICF syndrome (for immunodeficiency, centromere instabili

48 es in promoter methylation were seen between ICF and normal LCLs for three ICF upregulated genes and

49 alytic domain (null allele) and two carrying ICF-like missense mutations in the catalytic domain.

50 amer, and a greater vulnerability to certain ICF mutations.

51 a statistical 2:1 mixture of ICF(2)CF(2)CFHI:ICF(2)CFHCF(2)I.

52 ilibrium is made in nearly all computational ICF modeling and methods used to infer levels of contami

53 In contrast, ICF syndrome cells with DNMT3B mutations have L1s that a

54 Current ICF targets on the NIF utilize a gold or depleted uraniu

55 ase diagnostic yield relative to the current ICF algorithm but provided same-day diagnosis for 26% of

56 Compared with the current ICF algorithm, point-of-care CRP-based TB screening foll

57 AD system and sector-field ICP-MS detection (ICF-sfMS) with desolvating injection and optimization of

58 lassification of Functioning and Disability (ICF) as a theoretical framework and tested in a sample r

59 A human genetic disorder (ICF syndrome) has recently been shown to be caused by mu

60 F1 score.The application found 112 distinct ICF codes compared to 119 codes found by the domain expe

61 acortical inhibition (ICI) and facilitation (ICF) to the biceps brachii muscle proximal to the level

62 hibition (SICI), intracortical facilitation (ICF) and short-interval intracortical facilitation (SICF

63 ition (SICI) and intracortical facilitation (ICF) produced by a paired-pulse TMS, and forearm flexor

64 ition (SICI) and intracortical facilitation (ICF) were evaluated in the left and right M1 before and

65 ition (SICI) and intracortical facilitation (ICF) were evaluated in the masseter muscles of 12 subjec

66 hibition (SICI), intracortical facilitation (ICF), and cortical silent period (CSP).

67 ical inhibition, intracortical facilitation (ICF), and short-interval intracortical facilitation befo

68 nhibition (ICI), intracortical facilitation (ICF), resting (rMT) and active motor thresholds (aMT) we

69 nhibition (ICI), intracortical facilitation (ICF), the cortical silent period (SP) and spinal recipro

70 discharge to an institutional care facility (ICF) after surgery (age, 65-69 (3.3%); 70-74 (5.7%); 75-

71 ndrome (CFS) and idiopathic chronic fatigue (ICF).

72 we called the immune-mediated cancer field (ICF).

73 tuberculosis (TB) intensified case finding (ICF) algorithm for people living with HIV (symptom-based

74 strategies include intensified case finding (ICF), TB infection control, antiretroviral therapy (ART)

75 ettings, that more intensified case-finding (ICF) approaches may be needed to control TB transmission

76 n a presumed intracellular calcifying fluid (ICF) in closed vesicles and not, as previously assumed,

77 development and to create animal models for ICF syndrome, we have generated three mutant alleles of

78 ISIs): 2 and 3 ms for SICI, 10 and 15 ms for ICF and 1-5 ms for SICF.

79 ) were 2 and 3 ms for SICI, 10 and 15 ms for ICF.

80 ies in CpG islands of B cell lines from four ICF patients and their unaffected parents.

81 a (MCSA) and interstitial collagen fraction (ICF) histologically, and ejection fraction by ventriculo

82 Cells from ICF patients who are deficient in one of the DNA methylt

83 hese processes using cell lines derived from ICF syndrome and normal individuals.

84 Here, we generate iPSCs from ICF Type 1 syndrome patient fibroblasts followed by dire

85 B-cell lymphoblastoid cell lines (LCLs) from ICF patients with diverse DNMT3B mutations and on contro

86 Using inertial confinement fusion (ICF) as a test-bed problem, we model a one-dimensional s

87 s demonstrating inertial confinement fusion (ICF) ignition at the National Ignition Facility (NIF) ha

88 nto the fuel in inertial confinement fusion (ICF) implosions is a primary factor preventing ignition.

89 settings, from inertial confinement fusion (ICF) implosions over spatial scales of [Formula: see tex

90 physics such as inertial confinement fusion (ICF), is beyond the reach of conventional photon Doppler

91 sics (HEDP) and inertial confinement fusion (ICF), predictive modeling is complicated by uncertainty

92 cations such as inertial confinement fusion (ICF).

93 tion of Functioning, Disability, and Health (ICF) to provide a standardized terminology and framework

94 te marker of adaptation, such as that higher ICF and MT in the motor cortex is associated with lesser

95 How ICF mutations affect DNMT3B activity is not fully unders

96 However, ICF could not be obtained because it was masked by bilat

97 However, ICF DNA digests prominently displayed multicopy fragment

98 d intracortical inhibition/facilitation (ICI/ICF) curves.

99 ecreased at higher contraction levels; (iii) ICF was observed only at rest with S1 = 90% AMT; (iv) SI

100 oint-of-care CRP-based screening can improve ICF efficiency among people living with HIV.

101 e to TB-LAM and Xpert substantially improved ICF yield, identifying 78% of all TB cases.

102 dicating that the methylation abnormality in ICF is restricted to a small portion of the genome.

103 vily methylated at cytosine residues, but in ICF syndrome it is almost completely unmethylated in all

104 ing is also disrupted on the Y chromosome in ICF male cells.

105 itions such as optimizing fuel efficiency in ICF experiments.

106 h levels of DNA damage at chromosome ends in ICF cells, which are significantly reduced with overexpr

107 also pertain to abnormal gene expression in ICF.

108 Mutations of human DNMT3B are found in ICF syndrome, a developmental defect characterized by hy

109 The recent ignition in ICF calls for new velocimetry that can measure velocitie

110 suggest that abnormally high TERRA levels in ICF syndrome lead to accumulation of telomeric hybrids t

111 methylation in normal cells that was lost in ICF cells, concomitant with loss of repressive histone m

112 l levels of certain histone modifications in ICF cells, particularly ubiquitinated H2AK119.

113 lation and overexpression of NBL2 repeats in ICF samples suggests derangement of methylation-regulate

114 -wide DNA methylation patterns and result in ICF syndrome type 1 (ICF1).

115 site-specific epigenomic alterations seen in ICF syndrome with DNMT3B mutations.

116 , DNA methylation and chromatin structure in ICF cells remain relatively uncharacterized.

117 whereas INB+rTMSc reduced ICI and increased ICF, and conversely, INB+rTMSi deepened ICI and suppress

118 clear how mutations in any of the four known ICF genes cause a primary immunodeficiency.

119 annot be explained by mutations in the known ICF genes DNA methyltransferase 3B or zinc-finger and BT

120 ctional Independence Measure and the Lucerne ICF-based Multidisciplinary Observation Scale.

121 serum immunoglobulin levels which cause most ICF patients to succumb to infectious diseases before ad

122 e theoretical framework (items with multiple ICF codes), an exploratory PCA was conducted.

123 At S phase, CDCA7, but not ICF mutants, is concentrated in constitutive heterochrom

124 CDCA7, but not ICF mutants, preferentially binds the non-B DNA with str

125 e compared the yield and efficiency of novel ICF algorithms inclusive of point-of-care CRP-based TB s

126 gulated in several cancers and some cases of ICF syndrome.

127 y the mitotic defects that are a hallmark of ICF syndrome, a disease arising from germline mutations

128 data highlight the genetic heterogeneity of ICF syndrome; however, they provide evidence that all ge

129 I(2) to produce a statistical 2:1 mixture of ICF(2)CF(2)CFHI:ICF(2)CFHCF(2)I.

130 patients regarding the expected outcomes of ICF placement after surgical intervention.

131 centrally important for the pathogenesis of ICF syndrome.

132 NMT3L is not involved in the pathogenesis of ICF syndrome.

133 e examine further the molecular phenotype of ICF cells and report several examples of extensive hypom

134 mice show phenotypes that are reminiscent of ICF patients, including hypomethylation of repetitive se

135 pecify a frequency and duration of rounds of ICF.

136 onstrained and that the incremental yield of ICF is expected to wane over time as the pool of undiagn

137 There was no effect on ICF.

138 There were no effects on ICF, LICI or IHI.

139 Our studies of G6PD in one ICF female and SYBL1 in another ICF female provide the f

140 INB alone had no effect on ICI or ICF, whereas INB+rTMSc reduced ICI and increased ICF, an

141 Although ART has been widely rolled out, ICF and IPT have not.

142 omized study compared the IRB-approved paper ICF for an actual clinical research study with an intera

143 ropane with iodine at 240 degrees C produced ICF(2)CF(2)COF, which was quenched by alcohol, water, or

144 Thermolysis of the ring-opened product ICF(2)CF(2)CFIOR(F) at 240 degrees C gave R(F)I and ICF(

145 In BN rats, ICF was reduced and LVEF increased by AT(1)-ant, and bot

146 rning engine, Headai Graphmind, to recognize ICF codes from electronic health records written in Finn

147 ai Graphmind has the capability to recognize ICF codes from the electronic health records of patients

148 In BNK rats, the AT(1)-ant failed to reduce ICF, and its therapeutic effect on LVEF was significantl

149 Using the human sequence to screen ICF kindreds, we discovered mutations in four patients f

150 Second, ICF mutations cause a broad spectrum of biochemical defe

151 t of 32 genes had consistent and significant ICF-specific changes in RNA levels.

152 ked to perturbations of chromatin structure: ICF syndrome, facioscapulohumeral muscular dystrophy and

153 rsely, INB+rTMSi deepened ICI and suppressed ICF.

154 T3B are found in the developmental syndrome, ICF (immunodeficiency, centromeric heterochromatin insta

155 Third, all tested ICF mutations, including the A766P and R840Q variants, r

156 ferent stages of mouse development, and that ICF missense mutations cause partial loss of function.

157 We demonstrate that ICF syndrome cells, which exhibit short telomeres and el

158 While it does seem that ICF and MT may indicate a more acute marker of adaptatio

159 The ICF (immunodeficiency, centromeric instability and facia

160 The ICF region is conserved throughout the TRPM family, and

161 e to an ICF, the majority died either at the ICF (53.7%) or on a subsequent hospital admission (31.0%

162 le for channel function, which is called the ICF region.

163 of patients with early-stage HCC, called the ICF, that is associated with risk of HCC development in

164 levels for all DNMT3B isoforms, despite the ICF syndrome-linked DNMT3B deficiency causing juxtacentr

165 satellite regions are characteristic for the ICF immunodeficiency syndrome.

166 By contrast, mice homozygous for the ICF mutations develop to term and some survive to adulth

167 ations in the DNMT3B are responsible for the ICF syndrome.

168 We found the ICF gene expression pattern in 50% of liver tissues from

169 ethod could be helpful when implementing the ICF classification in clinical practice, and enable retr

170 ses, we identified a genomic sequence in the ICF region that contains the homologue of the mouse Dnmt

171 ur data suggest that DNMT3B mutations in the ICF syndrome cause lymphogenesis-associated gene dysregu

172 regulated expression of this sequence in the ICF syndrome.

173 Apart from CpG island methylation, the ICF inactive X is basically normal in that it forms a Ba

174 Because the unmethylated state of the ICF inactive X L1s probably reflects their methylation s

175 AEs (SAEs) were recorded from signing of the ICF until the end of the study.

176 r aspirin and clopidogrel down-regulated the ICF gene expression pattern in liver and developed fewer

177 omal recessive disorder, which is termed the ICF syndrome, for immunodeficiency, centromeric instabil

178 ese hamster ovary cells, suggesting that the ICF gene is conserved in the hamster and promotes de nov

179 nd cellular analyses further reveal that the ICF mutations of FF interface impair the DNA binding and

180 common or converging pathways leading to the ICF phenotype.

181 neurogenesis that are highly relevant to the ICF phenotype.

182 e acute transfer of K(+) from the ECF to the ICF, which may be important in exercise or ischemia.

183 We used the ICF to code AGQ item content before mailing the AGQ to a

184 The liver tissues with the ICF gene expression pattern had 3 different features: in

185 Within the ICF region, 10 amino acid residues form a domain essenti

186 e seen between ICF and normal LCLs for three ICF upregulated genes and one downregulated gene by a qu

187 al gene expression in ICF1-iPSCs relevant to ICF syndrome phenotypes, some directly associated with p

188 that are highly unstable in mitogen-treated ICF lymphocytes and B cell lines.

189 Two ICF missense mutations have been identified in the ZBTB2

190 findings demonstrate convergence of the two ICF genes ZBTB24 and CDCA7 at the level of transcription

191 thogenic and molecular mechanisms underlying ICF syndrome.

192 e, lymphoid-specific genes in 10 unexplained ICF cases.

193 llular calcifying fluid (ECF), which, unlike ICF, is partly open to seawater.

194 Here we show that five unrelated ICF patients have mutations in both alleles of the gene

195 The WHO ICF model was used to categorize outcome measures.

196 consistency across the components of the WHO ICF model.

197 n of Functioning, Disability and Health (WHO-ICF).

198 res, as observed in cells from patients with ICF (Immunodeficiency, Centromeric instability and Facia

199 sted for its ability to match free text with ICF codes on a sample of 20 patients.

200 racteristics of Me(3)Si-H...Y complexes (Y = ICF(3), BrCN, and HCN) containing a hydridic hydrogen we