ライフサイエンスコーパス: ICSI

1 ICSI offers no advantage over IVF in terms of clinical o

2 ICSI was performed in a programmed in vitro fertilizatio

3 r ICSI (total 435 treatment cycles: IVF 224; ICSI 211).

4 Analysis of pregnancies resulting from 987 ICSI cycles; pregnancy outcome data were obtained from t

5 thout male factor infertility (n = 317,996), ICSI use was associated with lower rates of implantation

6 n obliquely to the animal-vegetal axis after ICSI, with asymmetric furrows assembling from the male p

7 difference between children conceived after ICSI and their naturally conceived peers in terms of phy

8 olled trial comparing clinical outcome after ICSI or traditional IVF in couples with non-male-factor

9 Reports of higher fertilisation rates after ICSI suggest that this technique may be better than the

10 Multiplane videos after ICSI show atypical sperm head displacement beneath the o

11 patients fresh tissue provided sperm for an ICSI cycle.

12 domised trial included couples undergoing an ICSI procedure with fresh embryo transfer at 16 assisted

13 icantly between PICSI (27.4% [379/1381]) and ICSI (25.2% [346/1371]) groups (odds ratio 1.12, 95% CI

14 < .001) in offspring with ART conception and ICSI use were significantly higher than those in offspri

15 h cycles of IVF (in vitro fertilization) and ICSI (intracytoplasmic sperm injection) cycles, there is

16 The implications of male infertility and ICSI for the neurodevelopmental health of offspring rema

17 s with either male or female infertility and ICSI intervention.

18 productive outcomes for conventional IVF and ICSI cycles during 2008-2012, stratified by the presence

19 ive cohort study using data on fresh IVF and ICSI cycles reported to the US National Assisted Reprodu

20 surgical harvesting of testicular sperm and ICSI.

21 ded, treatment with microdissection TESE and ICSI are effective treatment options for many azoospermi

22 development, the removal of acrosomes before ICSI is recommended for animals with large sperm acrosom

23 m acrosomes, the removal of acrosomes before ICSI is theoretically preferable.

24 spermatozoa were freed from acrosomes before ICSI, regardless of the number of spermatozoa injected.

25 emembranated individually immediately before ICSI by using lysolecithin, a hydrolysis product of memb

26 studied 208 singleton children conceived by ICSI and a control group of 221 normally conceived singl

27 though the production of normal offspring by ICSI has been successful in mice and humans, it has been

28 s not a prerequisite to produce offspring by ICSI, but it resulted in earlier onset of oocyte activat

29 genital malformations following treatment by ICSI were within the range observed with standard in vit

30 the 578 neonates resulting from treatment by ICSI, 15 (2.6%) presented with congenital abnormalities

31 omparing ART versus OI/IUI or when comparing ICSI versus conventional IVF.

32 ions in mice produced by natural conception, ICSI and somatic cell nuclear transfer.

33 r Bologna Criteria, undergoing natural cycle ICSI between 2012 and 2020.

34 Among those cycles, ICSI use was associated with a lower multiple birth rate

35 Does ICSI have consequences that IVF does not?

36 portantly, some patients who repeatedly fail ICSI also fail to induce egg activation and are, therefo

37 ctable in sperm from patients who had failed ICSI.

38 at sperm from patients who repeatedly failed ICSI were unable to induce [Ca(2+)](i) oscillations in m

39 0.8 per 100,000 person-years); and following ICSI using ejaculated sperm and fresh embryos (RR, 1.47

40 creased risks of autistic disorder following ICSI using surgically extracted sperm and fresh embryos

41 son-years); for mental retardation following ICSI using surgically extracted sperm and fresh embryos

42 For ICSI, whether sperm were ejaculated or surgically extrac

43 (62.7 +/- 7.2% for IVF and 73.3 +/- 8.1% for ICSI) failed to litter after embryo transfer compared to

44 (20.4 +/- 7.9% for IVF and 28.1 +/- 10.7 for ICSI).

45 spermatogenesis who might be candidates for ICSI with sperm obtained directly from the testis.

46 Use of hyaluronan-based sperm selection for ICSI (so-called physiological ICSI [PICSI]) is reported

47 hypothesis, we uncoupled superovulation from ICSI by subjecting female mice to gonadotropin stimulati

48 ency of epimutations in somatic tissues from ICSI-derived mice.

49 and asthenoteratozoospermia, for which good ICSI prognosis is suggested.

50 In both male and female infertility groups, ICSI had unfavorable implications for the neurodevelopme

51 (ICSI and cap), the control algorithm guided ICSI to quickly achieve and maintain the target temperat

52 Trends in ICSI use during 1996-2012 with respect to male factor in

53 ; for those without male factor infertility, ICSI use increased from 15.4% (4197/27,191) to 66.9% (42

54 Among cycles with male factor infertility, ICSI use increased from 76.3% (10,876/14,259) to 93.3% (

55 Intracarotid cold saline infusion (ICSI) is potentially much faster than whole-body cooling

56 atios with intracytoplasmic sperm injection (ICSI) (139 defects, 9.9%) were 1.77 (95% CI, 1.47 to 2.1

57 (IVF) or intra cytoplasmic sperm injection (ICSI) (733) and intra uterine insemination (IUI) (1196)

58 Using intracytoplasmic sperm injection (ICSI) and standard in vitro fertilization (IVF), we foun

59 nceived by intracytoplasmic sperm injection (ICSI) and who developed Angelman syndrome.

60 isation by intracytoplasmic sperm injection (ICSI) are at increased risk of neurodevelopmental delay.

61 outcome of intracytoplasmic sperm injection (ICSI) as a readout, we found that sperm with altered miR

62 to whether intracytoplasmic sperm injection (ICSI) for male infertility was used and whether embryos

63 Intracytoplasmic sperm injection (ICSI) has been used in combination with testicular sperm

64 s rates of intracytoplasmic sperm injection (ICSI) include binding to hyaluronic acid (herein termed

65 Intracytoplasmic sperm injection (ICSI) is a more invasive option than conventional in-vit

66 Intracytoplasmic sperm injection (ICSI) is a technique that in vitro fertilization clinics

67 Intracytoplasmic sperm injection (ICSI) is increasingly used in patients without severe ma

68 n 5 min of intracytoplasmic sperm injection (ICSI) or somatic cell nuclear transfer (SCNT), and compl

69 nerated by intracytoplasmic sperm injection (ICSI) revealed that macroH2A is associated exclusively w

70 (IVF) and intracytoplasmic sperm injection (ICSI) treatment due to undisturbed embryo culture condit

71 us OI/IUI; intracytoplasmic sperm injection (ICSI) versus conventional in vitro fertilization (IVF);

72 Intracytoplasmic sperm injection (ICSI) was initially developed as part of in vitro fertil

73 Intracytoplasmic sperm injection (ICSI) was, ultimately, required to conceive a child.

74 the use of intracytoplasmic sperm injection (ICSI), a type of ART.

75 rated that intracytoplasmic sperm injection (ICSI), a type of assisted reproductive technology (ART),

76 (IVF) with intracytoplasmic sperm injection (ICSI), can be used as an adjunctive measure to allow for

77 Intracytoplasmic sperm injection (ICSI), however, can enable men to achieve fatherhood, an

78 ination of intracytoplasmic sperm injection (ICSI), in vitro fertilization (IVF), sperm removal, rein

79 (IVF) and intracytoplasmic sperm injection (ICSI), offering a promising solution to male infertility

80 Intracytoplasmic sperm injection (ICSI), the most common type of assisted reproductive tec

81 duction of intracytoplasmic sperm injection (ICSI).

82 ess called intracytoplasmic sperm injection (ICSI).

83 (IVF), or intracytoplasmic sperm injection (ICSI).

84 n, such as intracytoplasmic sperm injection (ICSI).

85 n (IVF) or intracytoplasmic sperm injection (ICSI).

86 ved during intracytoplasmic sperm injection (ICSI).

87 n (IVF) or intracytoplasmic sperm injection (ICSI).

88 (TESE) and intracytoplasmic sperm injection (ICSI).

89 y intracytoplasmic headneck sperm injection (ICSI).

90 ng WT sperm-derived total or small RNAs into ICSI embryos.

91 Compared with conventional IVF, ICSI use was not associated with improved postfertilizat

92 s with women undergoing fresh and frozen IVF/ICSI cycles; with extractable per woman data on pregnanc

93 cific instances in which sperm retrieval/IVF/ICSI may be a more appropriate treatment modality as ART

94 F) model had the highest accuracy in the IVF/ICSI treatment.

95 nted H19 gene in spermatogonia from juvenile ICSI-derived male mice.

96 The combination model had lower ICSI flow rates than the ICSI model resulting in a 55% r

97 ortex-only pronuclear interactions mimicking ICSI.

98 In the ICSI and the combination models (ICSI and cap), the control algorithm guided ICSI to quic

99 Comparison of ICSI with conventional IVF yielded similar pattern (POR

100 One drawback of ICSI is hemodilution and volume loading.

101 of acrosomes may increase the efficiency of ICSI in these animals.

102 ity of CatSper-deficient men and the need of ICSI for medically assisted reproduction.

103 Furthermore, when pregnancy outcome of ICSI vs IVF was analyzed in terms of semen origin, no di

104 The ratio of ICSI procedures to diagnoses of male-factor infertility

105 ith insurance coverage had a higher ratio of ICSI use to diagnoses of male-factor infertility than di

106 , uncertain efficacy, and potential risks of ICSI, its use has been extended to include some patients

107 The percentage of IVF cycles with the use of ICSI also increased dramatically (from 11.0% to 57.5%),

108 , to determine temporal trends in the use of ICSI and IVF in the United States, and we examined diffe

109 s, and we examined differences in the use of ICSI between states with and those without mandated insu

110 d each year, suggesting an increasing use of ICSI for conditions other than male-factor infertility.

111 F services is associated with greater use of ICSI for infertility that is not attributed to male-fact

112 Since 1995, the use of ICSI in the United States has increased dramatically, wh

113 1999 to 2004, there was an increasing use of ICSI relative to the percentage of patients with male-fa

114 store-operated Ca(2+) entry had no effect on ICSI-induced egg activation, so Ca(2+) influx through al

115 ion of a single spermatozoon into an oocyte (ICSI) can produce apparently normal offspring.

116 ndomly assigned to receive PICSI (n=1387) or ICSI (n=1385), of whom 2752 (1381 in the PICSI group and

117 our UK centres were randomly assigned IVF or ICSI (total 435 treatment cycles: IVF 224; ICSI 211).

118 lled trial in participants undergoing IVF or ICSI at seven IVF centres in the UK and Hong Kong.

119 UI group, and 35.8 (4.9) years in the IVF or ICSI group.

120 their chance of fathering children by IVF or ICSI reduced by nearly two-thirds.

121 ceiving their first, second, or third IVF or ICSI treatment and could not participate if using donor

122 In women undergoing IVF or ICSI treatment, the use of time-lapse imaging systems fo

123 on and embryo utilization rates after IVF or ICSI, biochemical and clinical pregnancy rates, first-tr

124 ith reduced incidence of pregnancy by IVF or ICSI, identifying SPTRX3 as a candidate biomarker reflec

125 For example, following IVF or ICSI, the proportion mediated by cesarean birth was 29%,

126 I or IUI, and 23 519 (1.7%) following IVF or ICSI.

127 I, and 1.16 (95% CI, 1.04-1.28) after IVF or ICSI.

128 as 44.3%, with a resultant delivery rate per ICSI cycle of 38.7% (n=382).

129 selection for ICSI (so-called physiological ICSI [PICSI]) is reported to reduce the proportion of pr

130 n 15-60 min after entry, and by 120 min post-ICSI or IVF, sperm were unable to induce oscillations.

131 ts support the current practice of reserving ICSI only for severe male-factor problems.

132 rgical reconstruction versus sperm retrieval/ICSI/IVF are neither randomized nor homogenous.

133 system to receive either PICSI or a standard ICSI procedure.

134 tigate the efficacy of PICSI versus standard ICSI for improving livebirth rates among couples undergo

135 Among fresh IVF cycles in the United States, ICSI use increased from 36.4% in 1996 to 76.2% in 2012,

136 In this study, ICSI was conducted using sperm heads from the Meig1 KO m

137 intracytoplasmic sperm injection technique (ICSI) from severely damaged spermatozoa that are no long

138 ies of postchemotherapy microdissection TESE-ICSI to date.

139 We discuss the possibility that ICSI may interfere with the establishment of the materna

140 Further studies are necessary to show that ICSI in humans, using headneck sperm cells, is viable an

141 Membrane flow drives polar bodies and the ICSI site into the furrow.

142 A follow-up rate of 90% for the ICSI group was achieved at a mean age of 17 months.

143 We examined germ cells from the ICSI mice that exhibited epimutations in their somatic c

144 In the ICSI and the combination models (ICSI and cap), the cont

145 rate was higher in the IVF group than in the ICSI group (95/318 [30%] vs 72/325 [22%]; relative risk

146 752 (1381 in the PICSI group and 1371 in the ICSI group) were included in the primary analysis.

147 ncluding 31 in the PICSI group and 25 in the ICSI group; most were congenital abnormalities and none

148 Moreover, in the combination model, the ICSI flow rate decreased to zero after 4h, and hypotherm

149 crotubules, and the animal pole, but not the ICSI site.

150 Epimutations were detected in most of the ICSI-derived mice, but not in somatic cells of their off

151 ion model had lower ICSI flow rates than the ICSI model resulting in a 55% reduction of infusion volu

152 animal pole, but typically, not through the ICSI injection site.

153 and higher hematocrit values compared to the ICSI model.

154 -Trypsin-Leishman (GTL) banding prior to the ICSI procedure at the Fertility Centre of Lanka Hospital

155 d Ca(2+) transient, whereas BAPTA/AM-treated ICSI or fertilized eggs cultured in Ca(2+)-free medium r

156 reproductive outcomes of couples undergoing ICSI treatment.

157 from 1996 through 2012, 908,767 (65.1%) used ICSI and 499,135 (35.8%) reported male factor infertilit

158 rain temperature control was developed where ICSI flow rate was varied based on the rate of temperatu

159 rate (per injected oocyte) was achieved with ICSI allowing a 50% clinical pregnancy rate with a live

160 The risk of birth defects associated with ICSI remained increased after multivariate adjustment, a

161 y significant, but the risks associated with ICSI using frozen embryos were significant for mental re

162 e risks of autistic disorder associated with ICSI using surgically extracted sperm were not statistic

163 Compared with ICSI, PICSI does not significantly improve term livebirt

164 ooling caps could enhance brain cooling with ICSI and minimize hemodilution and volume loading.

165 For specific procedures, IVF with ICSI for paternal infertility was associated with a smal

166 r absence of sperm, fertilization rates with ICSI, and final outcomes of pregnancy were recorded.

167 was significantly shorter with IVF than with ICSI (22.9 [SD 12.1] vs 74.0 [38.1] min; 95% CI for diff

168 ievable testis sperm, which may be used with ICSI to have healthy offspring.

169 IVF procedures used in Sweden vs IVF without ICSI with fresh embryo transfer, the most common treatme

170 Compared with IVF without ICSI with fresh embryo transfer, there were statisticall

171 mental retardation compared with IVF without ICSI.

172 Male or female infertility with or without ICSI.