ライフサイエンスコーパス: IFN-stimulated gene

1 e CXCL10, which is considered an interferon (IFN)-stimulated gene.

2 urenine pathway (KP) and a known interferon (IFN)-stimulated gene.

3 g proinflammatory cytokines, chemokines, and IFN-stimulated genes.

4 ession of costimulatory molecules and type I IFN-stimulated genes.

5 s increases the expression of IFNbeta and of IFN-stimulated genes.

6 ons (IFNs) and the activation of hundreds of IFN-stimulated genes.

7 ne response associated with the induction of IFN-stimulated genes.

8 rols IFN signaling and thereby expression of IFN-stimulated genes.

9 ression of type I interferon (IFN) and other IFN-stimulated genes.

10 at leads to the transcription of hundreds of IFN-stimulated genes.

11 arietal epithelial cells to express numerous IFN-stimulated genes.

12 severe COVID-19, and transient expression of IFN-stimulated genes.

13 d particularly strong expression of Ifnb and IFN-stimulated genes.

14 by inducing the transcription of hundreds of IFN-stimulated genes.

15 fecting expression of IFN-beta-stimulated or IFN-stimulated genes.

16 ing IFN-alpha secretion and the induction of IFN-stimulated genes.

17 duced expression of IFN-beta, IFN-lambda and IFN-stimulated genes.

18 low levels of type III IFN protein activate IFN-stimulated genes.

19 production of type I IFN and some classical IFN-stimulated genes.

20 esponsible for feed-forward amplification of IFN-stimulated genes.

21 e in the transcription of type I interferon (IFN)-stimulated genes.

22 The ubiquitin-like interferon (IFN)-stimulated gene 15 (ISG15) and its specific E1, E2,

23 Of these, IFN-stimulated gene 15 (ISG15) is one of the most upregu

24 IFN type I signature with activation of the IFN-stimulated gene 15 (ISG15) pathway.

25 The IFN-stimulated gene 15 (ISG15) system emerges as a major

26 IFN-stimulated gene 15 (ISG15), an IFN-induced ubiquitin

27 n the generation of IFN responses, including IFN-stimulated gene 15 (ISG15), p21(WAF1/CIP1), and Schl

28 Minimal IFN-stimulated gene 15 and IFIT1 responses peaked 1-2 wk

29 strate that IFN-inducible eIF4B activity and IFN-stimulated gene 15 protein (ISG15) or IFN-gamma-indu

30 ubiquitinating and deISGylating (interferon [IFN]-stimulated gene 15 [ISG15]-removing) enzymes on hos

31 ases production of IFNbeta and expression of IFN-stimulated genes 48 h after infection.

32 appeared not to correlate with induction of IFN-stimulated genes 54 and 56, which were detected in h

33 nhibitors also showed the ability to inhibit IFN-stimulated gene 56 induction mediated by TLR4 and TL

34 Using the IFN-stimulated gene 56 promoter-driven firefly luciferas

35 A, 2',5'-oligoadenylate synthetase, and the IFN-stimulated gene 56.

36 RNA knockdown of Socs-1 resulted in induced IFN-stimulated gene-56 and Tlr7 expression following WNV

37 ere attributed to overexpression of Tlr7 and IFN-stimulated gene-56 expression, whereas reduced expre

38 ith an increase in type I IFN production and IFN-stimulated gene accumulation upon infection.

39 the transcriptional induction of hundreds of IFN-stimulated genes, among them sensory pathway compone

40 ading to increased expression of interferon (IFN)-stimulated genes and activation of natural killer (

41 e I IFN, as measured by a marked increase in IFN-stimulated genes and a decrease in HCV load.

42 lasts exhibited constitutive upregulation of IFN-stimulated genes and an enhanced type I IFN response

43 quently, circulating monocytes express fewer IFN-stimulated genes and become permissive for CHIKV inf

44 sponded to IFN-a by increasing expression of IFN-stimulated genes and decreasing expression of genes

45 The induction of type I IFNs, IFN-stimulated genes and dendritic cell maturation by ch

46 y developed as mESCs express lower levels of IFN-stimulated genes and display weaker antiviral activi

47 emory T cells showed up-regulation of type 1 IFN-stimulated genes and inhibition with histone methylt

48 tent transcription factor of type I IFNs and IFN-stimulated genes and is known as the master regulato

49 ct-acting antiviral normalizes expression of IFN-stimulated genes and NK cell function.

50 y increased expression of type I and type II IFN-stimulated genes and proapoptotic genes.

51 splayed kinetic differences in expression of IFN-stimulated genes and proinflammatory responses, with

52 translation-arrested cells still transcribed IFN-stimulated genes and secreted IFNs of types I and II

53 WHSC1 and HIRA co-occupied IFN-stimulated genes and supported prolonged H3.3 incorp

54 cells with etoposide led to the induction of IFN-stimulated genes and the IFN-alpha and IFN-lambda ge

55 type I IFN, despite similar upregulation of IFN-stimulated genes and viral restriction factors.

56 ted a potent interferon-lambda (IFN-lambda), IFN-stimulated gene, and cytokine response in HepG2-HFL

57 nfection, transcription of interferon (IFN), IFN-stimulated genes, and inflammatory genes was induced

58 are able to respond to type I IFNs, express IFN-stimulated genes, and mediate the antiviral effect o

59 ense mechanism through the induction of IFN, IFN-stimulated genes, and other proinflammatory cytokine

60 expression of IFN-alpha, IFN-beta, multiple IFN-stimulated genes, and T cell-polarizing factors with

61 These data now provide a link between IFN, IFN-stimulated genes, and the inflammatory and possibly

62 leveraged to address the association of IFN, IFN-stimulated genes, and the phenotype of macrophages i

63 of type I IFN signaling, the highly related IFN-stimulated genes Apolipoprotein L9a and b activate e

64 Enhanced expression of LGP2 suppresses the IFN stimulated genes associated with cytotoxic stress by

65 lpha results in the induction of a subset of IFN-stimulated genes associated with antiviral activity

66 IEGs include not only IFN-stimulated genes, but other nontranscriptionally ind

67 ex that drives the expression of a subset of IFN-stimulated genes, but with substantially delayed kin

68 interferons (IFNs) induce the expression of IFN-stimulated genes by activating phosphorylation of bo

69 ht to limit the induction of type I IFNs and IFN-stimulated genes by shutting off host cell macromole

70 that activated mouse macrophages lacking the IFN-stimulated gene cholesterol 25-hydroxylase (Ch25h) a

71 FN-beta, myxovirus resistance protein A, and IFN-stimulated genes, compared with C-HIV and CI-HIV.

72 Expression of a set of IFN-stimulated genes comprises an IFN-related DNA damage

73 Additionally, the IFN-stimulated genes Cxcl10, Ifit1, Ifit3, and Mx2 can b

74 those with asthma had increased induction of IFN-stimulated genes DExD/H-box helicase 58, MX dynamin-

75 endent TNBC cell lines also exhibit elevated IFN stimulated gene expression.

76 virus along with IFN-beta and IFN-lambda and IFN-stimulated gene expression (tracked by 2'-5'-oligoad

77 A5 restricted HRV infection while increasing IFN-stimulated gene expression and IFN-beta/lambda.

78 h RIG-I signaling reduced IFN production and IFN-stimulated gene expression and increased viral repli

79 leads to persistently high levels of type I IFN-stimulated gene expression and to increased resistan

80 solution of type I IFN (IFN-I) responses and IFN-stimulated gene expression during the acute-to-chron

81 ieres syndrome (AGS) mouse model and reduced IFN-stimulated gene expression in cells from a patient w

82 temic antiviral activity and upregulation of IFN-stimulated gene expression in the upper respiratory

83 IFN signaling correlated with an increase in IFN-stimulated gene expression levels during HEV replica

84 Furthermore, these IFNs induced IFN-stimulated gene expression predominantly in monocyte

85 n-deficient UV-irradiated virus, and IFN and IFN-stimulated gene expression was determined by quantit

86 Viral RNA shedding and IFN-stimulated gene expression were measured by quantita

87 uring or shortly before maximal intrahepatic IFN-stimulated gene expression, but disappeared prior to

88 s not only provoke type I IFN production and IFN-stimulated gene expression, mirroring the response o

89 lls were impaired in their ability to induce IFN-stimulated gene expression, which resulted in enhanc

90 ranscription factor central for IFN-beta and IFN-stimulated gene expression.

91 nterferon (IFN-alpha) treatment by impairing IFN-stimulated gene expression.

92 nnate immune response including intrahepatic IFN-stimulated gene expression.

93 both viral proteins impacting 'globally' on IFN-stimulated gene expression.

94 ted cells leads to type I IFN production and IFN-stimulated gene expression.

95 correlated well with functional activity and IFN-stimulated gene expression.

96 STAT-1, but not other members of interferon (IFN)-stimulated gene factor 3 (ISGF-3) complex such as S

97 imeric transcription factor complex known as IFN-stimulated gene factor 3 (ISGF3) and the subsequent

98 ponse elements (ISREs) that bind to both the IFN-stimulated gene factor 3 (ISGF3) as well as to IFN r

99 ptosis of macrophages proceeds through tonic IFN-stimulated gene factor 3 (ISGF3) signaling, which le

100 -alpha and IFN-beta) induces the assembly of IFN-stimulated gene factor 3 (ISGF3), a multimeric trans

101 ers, gene transcription was mainly driven by IFN-stimulated gene factor 3 (ISGF3).

102 the involvement of JAK1 and TYK2, as well of IFN-stimulated gene factor 3 (ISGF3).

103 with type I IFNs activates the formation of IFN-stimulated gene factor 3 (STAT1/STAT2/IFN regulatory

104 related with high levels of unphosphorylated IFN-stimulated gene factor 3 (U-ISGF3), which was previo

105 ction of antiviral genes that are induced by IFN-stimulated gene factor 3 and associated with a type

106 In this study, we show that IFN-stimulated gene factor 3 containing unphosphorylated

107 Although the identical transcription factor, IFN-stimulated gene factor 3 is activated by either IFN-

108 These data show that IFN-stimulated gene factor 3 or STAT1 homodimers are not

109 TAT1- and STAT2-containing complexes such as IFN-stimulated gene factor 3.

110 ated by screening a library of more than 350 IFN-stimulated genes for antiviral activity.

111 Pattern recognition receptors and IFN-stimulated genes had higher basal and IFN-induced ex

112 Comprehensive catalogs of IFN-stimulated genes have been established across specie

113 738409 C>G polymorphisms were genotyped; and IFN-stimulated gene hepatic expression (n = 16) was test

114 e mechanism, we also evaluated the impact on IFN-stimulated gene hepatic expression in a subset of pa

115 represent a heretofore unknown class of non-IFN-stimulated gene IEGs.

116 An siRNA screen targeting 89 IFN stimulated genes in 14 different cancer cell lines p

117 oduction, or those involved in activation of IFN stimulated genes in response to binding of IFN with

118 examined H3.3 incorporation into interferon (IFN)-stimulated genes in confluent mouse NIH3T3 cells ex

119 vated during the antiviral response, placing IFN-stimulated genes in a functional context, and serves

120 e induction of type I interferon (IFN-I) and IFN-stimulated genes in cells infected with an IFN-induc

121 ication within Huh7.5.1 cells, also inducing IFN-stimulated genes in co-culture.

122 rn molecules increased induction of IFNs and IFN-stimulated genes in HLSECs.

123 produced by Dicer enhanced the expression of IFN-stimulated genes in MDAH087-N cells resulting in sig

124 increased intratumoural expression of type I IFN-stimulated genes in patients with cancer, confirming

125 serum, and upregulated expression of several IFN-stimulated genes in peripheral blood mononuclear cel

126 on (IFN) production as well as expression of IFN-stimulated genes in response to exogenously added IF

127 miR-BART16 abrogates the production of IFN-stimulated genes in response to IFN-alpha stimulatio

128 eficiency results in increased expression of IFN-stimulated genes in response to type I IFN and leads

129 ll RNA sequencing revealed that induction of IFN-stimulated genes in response to viral infection was

130 profiling revealed a strong up-regulation of IFN-stimulated genes in the blood of treated animals, co

131 nits of HDLs containing IA, the induction of IFN-stimulated genes in the brain was significantly grea

132 s exhibited very limited induction of type I IFN-stimulated genes in the liver compared with chimpanz

133 has focused on a potential role for IFN and IFN-stimulated genes in the pathogenesis of congenital h

134 c cell line THP-1 results in an induction of IFN-stimulated genes in these cells.

135 ompletely abrogates spontaneous induction of IFN-stimulated genes in TREX1-deficient cells.

136 ted type I IFNs and several antiviral genes (IFN-stimulated genes) in the intestine by bulk analysis,

137 inked with an upregulation of IFN and type I IFN-stimulated genes, including sialic acid-binding Ig-l

138 with increased transcription of interferon (IFN)-stimulated genes independent of IFN-alpha, -beta, a

139 IFN-stimulated gene induction was also delayed in Irf-3(

140 cts except for a subset in which the lack of IFN-stimulated gene induction was associated with increa

141 d skin 24 h postinfection where the level of IFN-stimulated gene induction was parasite strain-depend

142 ta reporter mice, and investigation of local IFN-stimulated gene induction) revealed that MyTrCa(-/-)

143 , whereas IFN-lambda provides a long-lasting IFN-stimulated gene induction.

144 hese cells, suggesting that transcription of IFN-stimulated genes is dependent on IFI16.

145 Translation of type I IFN-stimulated genes is first elevated in the BM, preced

146 this SUMO switch in TRIM28, the induction of IFN-stimulated genes is limited unless expression of the

147 ages lacking TRIM14 dramatically hyperinduce IFN stimulated gene (ISG) expression following M. tuberc

148 ponse to invading pathogens, and interferon (IFN)-stimulated gene (ISG) activation is a central featu

149 aling that upregulates antiviral interferon (IFN)-stimulated gene (ISG) expression in uninfected remo

150 gorous intrahepatic induction of interferon (IFN)-stimulated gene (ISG) induction is a feature of hep

151 CV persists in the liver despite interferon (IFN)-stimulated gene (ISG) induction; robust induction a

152 , phosphorylated STAT1 (P-STAT1) levels, and IFN-stimulated gene (ISG) expression compared to control

153 dly, we found that GR dramatically inhibited IFN-stimulated gene (ISG) expression in macrophages.

154 es cell type-specific differences in IFN and IFN-stimulated gene (ISG) expression in response to exog

155 he effect of IL-28B genotypes on IL-28B, and IFN-stimulated gene (ISG) expression, and CMV replicatio

156 lambda proteins (IL28B, IL-29), preactivated IFN-stimulated gene (ISG) expression, and impaired Stat

157 Ns, which trigger antiviral defenses through IFN-stimulated gene (ISG) expression.

158 skin, and lymphoid tissues were examined for IFN-stimulated gene (ISG) induction and infiltration by

159 licons was not correlated with inhibition of IFN-stimulated gene (ISG) mRNA induction, yet ISG induct

160 rate suppresses levels of specific antiviral IFN-stimulated gene (ISG) products, such as RIG-I and IF

161 s virus growth by inducing a large number of IFN-stimulated gene (ISG) proteins, several of which hav

162 ber of cellular genes, collectively known as IFN-stimulated gene (ISG) proteins, which act as antivir

163 cells lacking PR exhibited higher levels of IFN-stimulated gene (ISG) RNA, the transcriptional end p

164 An IFN-stimulated gene (ISG) signature was detected in the

165 ze the output of IFN signaling, specifically IFN-stimulated gene (ISG) signatures, in primary tumors

166 ished, but the specific contribution of each IFN-stimulated gene (ISG) to these biological responses

167 urther experiments indicated that cGAS is an IFN-stimulated gene (ISG), and two adjacent IFN-sensitiv

168 codes viperin), an enigmatic multifunctional IFN-stimulated gene (ISG).

169 ereby inducing the expression of IFNbeta and IFN-stimulated genes (ISG) in breast cancer cells in vit

170 lving infection, suggesting that a subset of IFN-stimulated genes (ISG) may play a role in the contro

171 cells, they induce transcription of numerous IFN-stimulated genes (ISG), which in turn protect these

172 f genes involved in IFN signaling, including IFN-stimulated genes (ISG).

173 R), chitinase-3-like protein 1 (CHI3L1), and IFN-stimulated genes (ISG).

174 secretion and transcriptional activation of IFN-stimulated genes (ISG).

175 The transcript levels of IFN-stimulated genes ISG15 and ISG56 and protein level o

176 a resulted in the upregulation of four model IFN stimulated genes (ISGs) in HEL-299 and HEL-TERT cell

177 sponding cells through induction of a set of IFN stimulated genes (ISGs) with regulatory or antiviral

178 uced the expression of IFN-beta and multiple IFN stimulated genes (ISGs), including Myxovirus resista

179 ARDS have elevated expression of interferon (IFN) stimulated genes (ISGs) associated with decreased c

180 f genes previously classified as interferon (IFN) stimulated genes (ISGs) but that expression is intr

181 Interferon (IFN)-stimulated genes (ISGs) and extracellular matrix re

182 his study was to examine whether interferon (IFN)-stimulated genes (ISGs) are overexpressed in human

183 hich regulates the expression of interferon (IFN)-stimulated genes (ISGs) by biogenesis of RA.

184 on by inducing expression of the interferon (IFN)-stimulated genes (ISGs) in Huh7 cells.

185 the function of the HCMV-induced interferon (IFN)-stimulated genes (ISGs) in infected monocytes remai

186 and subsequent up-regulation of interferon (IFN)-stimulated genes (ISGs) in patients with SAVI.

187 es the expression of a subset of interferon (IFN)-stimulated genes (ISGs) in the absence of IFNs.

188 pes to differential induction of interferon (IFN)-stimulated genes (ISGs) in the liver of patients wi

189 for PRDM16 in suppressing type I interferon (IFN)-stimulated genes (ISGs), including Stat1, in adipoc

190 expression of several antiviral interferon (IFN)-stimulated genes (ISGs).

191 yed significant up-regulation of type I IFN (IFN)-stimulated genes (ISGs).

192 n increased expression of IFN-beta and other IFN-stimulated genes (ISGs) (e.g., PKR, MDA5, IRF1, IRF7

193 nts, metformin inhibits the transcription of IFN-stimulated genes (ISGs) after IFN-alpha treatment.

194 to IFN treatment, were robustly recruited to IFN-stimulated genes (ISGs) after stimulation.

195 d with paradoxically decreased expression of IFN-stimulated genes (ISGs) and gamma interferon (IFN-ga

196 viral immunity by inducing the expression of IFN-stimulated genes (ISGs) and mediating signals downst

197 atory networks that control transcription of IFN-stimulated genes (ISGs) and mRNA translation, leadin

198 including IFN-alpha, upregulate an array of IFN-stimulated genes (ISGs) and potently suppress Human

199 Interferon (IFN) and IFN-stimulated genes (ISGs) are amplified during HCV inf

200 Interferon (IFN) and IFN-stimulated genes (ISGs) are amplified during HCV inf

201 ) production and the subsequent induction of IFN-stimulated genes (ISGs) are highly effective innate

202 We observed increased expression of type 1 IFN-stimulated genes (ISGs) as the predominant transcrip

203 levels of type I and type III IFN genes and IFN-stimulated genes (ISGs) at 37 degrees C.

204 t JAK/STAT-dependent upregulation of several IFN-stimulated genes (ISGs) at both the mRNA and protein

205 cific subset of genes during infection, with IFN-stimulated genes (ISGs) being the most affected by b

206 P40) proteins each inhibit the production of IFN-stimulated genes (ISGs) by blocking Jak-STAT signali

207 ducible gene I (RIG-I) and several antiviral IFN-stimulated genes (ISGs) expression.

208 Screening of a library of more than 350 IFN-stimulated genes (ISGs) identified interferon-regula

209 The actions of IFN-stimulated genes (ISGs) impart control of virus infe

210 and ovarian carcinoma cell lines, represses IFN-stimulated genes (ISGs) in a BRCA2-dependent manner,

211 t IRF4 directly induced a specific subset of IFN-stimulated genes (ISGs) in a type I IFN-independent

212 cient to induce transcription of a subset of IFN-stimulated genes (ISGs) in an IRF3-dependent, IFN-in

213 sponse, including widespread upregulation of IFN-stimulated genes (ISGs) in blood and lymph nodes.

214 uced IFN-beta secretion and transcription of IFN-stimulated genes (ISGs) in both RIG-I(-/-) and MDA-5

215 ssion of SV40 LT results in the induction of IFN-stimulated genes (ISGs) in human fibroblasts and con

216 e was accompanied by rapid downregulation of IFN-stimulated genes (ISGs) in liver and blood, regardle

217 with constitutively increased expression of IFN-stimulated genes (ISGs) in the liver.

218 STAT3 phosphorylation and the expression of IFN-stimulated genes (ISGs) IRF1, IRF7, and MxA.

219 We observed a >300-fold reduction in the IFN-stimulated genes (ISGs) MxA and ISG56 following TULV

220 -of-function genetic screening of individual IFN-stimulated genes (ISGs) on hepadnaviral mRNAs transc

221 terns of expression of interferons (IFN) and IFN-stimulated genes (ISGs) provided important insights

222 hypothesized that there must be a subset of IFN-stimulated genes (ISGs) regulated by IFN-gamma in a

223 However, many IFN-stimulated genes (ISGs) rely on antiviral pathways t

224 formatic analysis, we identified a number of IFN-stimulated genes (ISGs) specifically activated durin

225 ue damage and induces the expression of many IFN-stimulated genes (ISGs) that encode host-protective

226 To identify IFN-stimulated genes (ISGs) that instigate an antiviral

227 in infected and uninfected cells by inducing IFN-stimulated genes (ISGs) that modulate viral entry, r

228 A typical signature of IFN-stimulated genes (ISGs) was observed with both virus

229 Recently, increased levels of IFN-stimulated genes (ISGs) were described in COPA syndr

230 nonuclear cells and individual expression of IFN-stimulated genes (ISGs) were quantified on IFN thera

231 timulation upregulates hundreds of different IFN-stimulated genes (ISGs), but it is often unclear whi

232 rferon alfa (IFN-alpha) alters expression of IFN-stimulated genes (ISGs), but little is understood ab

233 rferon alfa (IFN-alpha) alters expression of IFN-stimulated genes (ISGs), but little is understood ab

234 autocrine loop and downstream expression of IFN-stimulated genes (ISGs), including chemokines CXCL9

235 increased expression of interferon (IFN) and IFN-stimulated genes (ISGs), including, among others, th

236 Similar to protein-coding IFN-stimulated genes (ISGs), its induction was dependent

237 n of selected IFN-regulatory factors (IRFs), IFN-stimulated genes (ISGs), transforming growth factor-

238 e antiviral mechanism of these cytokines, 37 IFN-stimulated genes (ISGs), which are highly inducible

239 knockdown of KLF7 inhibits the expression of IFN-stimulated genes (ISGs), which are necessary for KLF

240 o viral infection, the host induces over 300 IFN-stimulated genes (ISGs), which are the central compo

241 induce JAK-STAT signaling and expression of IFN-stimulated genes (ISGs), which mediate antiviral act

242 atterns (e.g., dsRNA) activate expression of IFN-stimulated genes (ISGs), which protect hosts from in

243 a group of antiviral effector proteins, the IFN-stimulated genes (ISGs), which target distinct viral

244 ts by inducing the expression of hundreds of IFN-stimulated genes (ISGs).

245 ron (IFN) signaling leading to expression of IFN-stimulated genes (ISGs).

246 to induce type I/III interferons (IFNs) and IFN-stimulated genes (ISGs).

247 of IFN regulatory factor 3 (IRF3)-dependent IFN-stimulated genes (ISGs).

248 rogression that depends on the expression of IFN-stimulated genes (ISGs).

249 IFN-alpha and IFN-beta) via the induction of IFN-stimulated genes (ISGs).

250 scades that lead to transcription of IFN and IFN-stimulated genes (ISGs).

251 ased type I IFN activity and upregulation of IFN-stimulated genes (ISGs).

252 n cells through the induction of hundreds of IFN-stimulated genes (ISGs).

253 ly antiviral response by inducing the type-I IFN-stimulated genes (ISGs).

254 ents leading to the induction of hundreds of IFN-stimulated genes (ISGs).

255 ctions, induce the expression of hundreds of IFN-stimulated genes (ISGs).

256 nt triggering expression of immediate early, IFN-stimulated genes (ISGs).

257 lar antiviral state through the induction of IFN-stimulated genes (ISGs).

258 nterleukin (IL)-28, and led to expression of IFN-stimulated genes (ISGs).

259 expression of Type III (lambda) IFNs and of IFN-stimulated genes (ISGs).

260 role for this pathway in mRNA translation of IFN-stimulated genes (ISGs).

261 order to impair transcriptional induction of IFN-stimulated genes (ISGs).

262 her components, most of which are encoded by IFN-stimulated genes (ISGs).

263 y suppress HIV-1 replication by upregulating IFN-stimulated genes (ISGs).

264 RNA Pol II recruitment to the IRF3-dependent IFN-stimulated genes (ISGs).

265 oteins to suppress activation of a subset of IFN-stimulated genes (ISGs).

266 Recombinant ovine IFNT (roIFNT) induced the IFN-stimulated genes (ISGs; MX2, ISG15, and OAS1Y).

267 rted upregulation of innate immune pathways (IFN-stimulated genes [ISGs]) of increasing magnitude wit

268 CV therapy; it up-regulates transcription of IFN-stimulated genes, many of which have been investigat

269 DC-specific arrays revealed upregulation of IFN-stimulated genes, most cytokines, and transcription

270 Two downstream IFN-stimulated genes, MxA and TRAIL, also show different

271 Broadly, IFN-stimulated genes negatively correlated with viral RN

272 tion of type I interferons (IFN-alpha/beta), IFN-stimulated genes (PKR, OAS, Mx1, and ISG15 genes), I

273 scription but had elevated levels of certain IFN-stimulated genes, presumably in response to exogenou

274 n inhibit expression of interferon (IFN) and IFN-stimulated gene products by inducing proteasome-medi

275 IFN regulatory factor 3, and augmentation of IFN-stimulated gene products.

276 in ribosomal composition that act to buffer IFN-stimulated gene protein synthesis.

277 ns of PVM lowered the levels of several ISG (IFN-stimulated gene) proteins as well.

278 approach, we identified a robust interferon (IFN)-stimulated gene response within microglia exposed t

279 to a severe attenuation of IFN-alpha and the IFN-stimulated gene retinoic acid-inducible gene I (RIG-

280 We observed a distinct activation of the IFN-stimulated gene signature with a substantial increas

281 ate a number of cellular mRNAs, including an IFN-stimulated gene target, IFIT1/ISG56, by destabilizin

282 type I IFN and upregulated the expression of IFN-stimulated genes (tetherin, IFITM3, and viperin), as

283 h7.5(dif) cells expressed a wider pattern of IFN-stimulated genes than undifferentiated Huh7.5 cells

284 esponses by evading restriction of Ifit1, an IFN-stimulated gene that regulates protein synthesis.

285 damage, but the mechanisms and identities of IFN-stimulated genes that are involved in this damage re

286 ng the induction patterns of closely related IFN-stimulated genes that are located adjacent to one an

287 s an increase in the transcription of type I IFN-stimulated genes that correlated with the observed i

288 o elevated transcription of a large group of IFN-stimulated genes that have antiviral function.

289 N is an accumulated effect of at least three IFN-stimulated genes that probably act on different stag

290 a selective suppression of IFN-alpha and the IFN-stimulated gene TRAIL while simultaneously inducing

291 he ability to induce endogenous IFN-beta and IFN-stimulated genes varies among these cytokines and wa

292 down MYC in the pDC cell line, production of IFN-stimulated genes was dramatically increased and was

293 frequencies were preserved, and induction of IFN-stimulated genes was noted in all subjects except fo

294 Robust induction of IFN-stimulated genes was observed in excised skin 24 h p

295 Expression of IFN-stimulated genes was up-regulated in anti-MDA5 DM; h

296 DS show increased expression of interferon (IFN)-stimulated genes, we have completed a comprehensive

297 of cell lines that overexpressed individual IFN-stimulated genes, we found that protein kinase R (PK

298 IFN-stimulated genes were also markedly upregulated, wit

299 IFN-stimulated genes were hypo-expressed in the liver of

300 quence-specific transcriptional repressor of IFN-stimulated genes, which occurs through antagonism of