ライフサイエンスコーパス: ILD

1 ILD events were more common among those with early/mild

2 ILD pattern was defined by high-resolution computed tomo

3 ILD was independently associated with IHD and HF, both o

4 hly lateralized; or (3) at the center near 0 ILD.

5 tal of 31,646 COPD, 60,424 asthma, and 1,662 ILD patients were included.

6 cHL and heart disease (EAR, 6.6; SMR, 1.7), ILD (EAR, 3.7; SMR, 13.1), and infections (EAR, 3.1; SMR

7 patients with alternative idiopathic ILDs (a-ILD; n = 41), and healthy control subjects (n = 127).

8 ished patients with IPF from patients with a-ILD, both individually and in a combined index.

9 entiated patients with IPF from those with a-ILD.

10 body mass, craniomandibular CS, and absolute ILDs including skull, basicranial, palatal, mandibular,

11 Common protein regulations across all ILD cases, as well as distinct ILD subsets, were observe

12 develops both inflammatory arthritis and an ILD that mimics a cellular nonspecific interstitial pneu

13 TD >/= 205 Gy and HILD < 120 Gy, applying an ILD > 150 Gy).

14 ith sufficient study time, 25 (19.4%) had an ILD event by 5 years after enrollment; of these, 12 met

15 increased ICU LOS for recipients with CF and ILD, but not in the COPD or "other" group.

16 of interstitial lung abnormalities (ILA) and ILD among relatives of patients with FPF and sporadic IP

17 uroendocrine cell hyperplasia of infancy and ILD, due to mutations in genes affecting surfactant prod

18 results to each other in simulating ITD and ILD coding.

19 oise, degrading the fidelity of both ITD and ILD cues.

20 , which reduced the dynamic range of ITD and ILD response functions and the ability of neurons to sig

21 Using a modeling approach, we assess ITD and ILD sensitivity of the neural filters to natural sounds,

22 conditions, cortical sensitivity to ITD and ILD takes the form of broad contralaterally dominated re

23 teraural time and level differences (ITD and ILD)-that correlate with sound-source locations.

24 ons suggest integrated processing of ITD and ILD.

25 perates in a similar manner on both ITD- and ILD-sensitive neurons, suggesting a shared mechanism ope

26 to amyloid formation of the SP-C protein and ILD.

27 preclinical models of systemic sclerosis and ILD.

28 eraural time and level differences (ITDs and ILDs), can be compromised by device processing.

29 As altered the relationship between ITDs and ILDs, introducing large ITD-ILD conflicts in some cases.

30 atients with rheumatoid arthritis-associated ILD (RA-ILD; n = 33), patients with alternative idiopath

31 RA-associated ILD (RA-ILD) exists on a wide spectrum, with variable le

32 e pathogenesis of fibrosis in SSc-associated ILD (SSc-ILD) involves cellular injury, activation/diffe

33 ncoding of ILDs, human and animal behavioral ILD sensitivity is robust to temporal stimulus degradati

34 Here we demonstrate that behavioral ILD sensitivity (in humans) and neural ILD sensitivity (

35 Here we demonstrate that behavioral ILD sensitivity is only modestly degraded with even comp

36 tical coupling and thermal isolation between ILDs and waveguides.

37 In contrast, one BRICHOS and one non-BRICHOS ILD-associated mutant could not insert into membranes.

38 Copa(E241K/+) mice are pathogenic and cause ILD through adoptive transfer experiments.

39 entities are distinct from those that cause ILD in older children and adults.

40 l lung disease (ILD) cases, (2) characterize ILD subgroups in an unbiased fashion, and (3) identify c

41 fants, who are regarded as having "childhood ILD syndrome"; (4) describe a new pathologic classificat

42 les that are highly effective in classifying ILD patients; and (3) stochastic simulation to design, t

43 inhibitory from the other: EI cells) compare ILDs separately over restricted frequency ranges which a

44 Recipients with COPD, ILD, or in the "other" group did not have inferior survi

45 nor age on survival in recipients with COPD, ILD, or in the "other" group in multivariate models.

46 t localization cues are integrated: cortical ILD tuning to broadband sounds is a composite of separat

47 mmon new-onset ILD in India, followed by CTD-ILD and idiopathic pulmonary fibrosis; diagnoses varied

48 (n = 513; exposure, 48.1% air coolers), CTD-ILD in 13.9%, and idiopathic pulmonary fibrosis in 13.7%

49 An adjudication panel determined ILD hospitalization and death.

50 Mutant mice spontaneously developed ILD that mirrors lung pathology in patients, as well as

51 d ILA, which likely precedes the development ILD in some cases.

52 ion test and lung HRCT screening to diagnose ILD early and tailor further management.

53 l plane uses an interaural-level difference (ILD) cue, yet little is known about the synaptic mechani

54 is modulated by interaural level difference (ILD) primarily through scaling excitation to different l

55 rences (ITDs), interaural level differences (ILDs) and the direction-dependent spectral filtering by

56 structure and interaural level differences (ILDs) from the stimulus envelope.

57 igs to compare interaural level differences (ILDs), a key localization cue, between tones of disparat

58 rences (ITDs), interaural level differences (ILDs), and pinna spectral cues, are all represented in t

59 tween a side-emitting injection laser diode (ILD) and a dielectric optical waveguide mixer via a grad

60 try (FC) data and interstitial lung disease (ILD) - a systemic sclerosis (SSc, or scleroderma) clinic

61 n toward clinical interstitial lung disease (ILD) among subjects in a longitudinal cohort of self-rep

62 rlying dyspnea in interstitial lung disease (ILD) and chronic obstructive pulmonary disease (COPD) ar

63 ts with fibrosing interstitial lung disease (ILD) and determine whether there are differences among t

64 in patients with interstitial lung disease (ILD) and may reflect immunologic activation and subseque

65 gold standard-in interstitial lung disease (ILD) cases requiring histology remains controversial.

66 across end-stage interstitial lung disease (ILD) cases, (2) characterize ILD subgroups in an unbiase

67 rogressive, fatal interstitial lung disease (ILD) characterized by abnormal extracellular matrix (ECM

68 ts suffering from interstitial lung disease (ILD) due to mutations in the gene of the precursor prote

69 on patients with interstitial lung disease (ILD) has not been established.Objectives: To assess outc

70 es on subclinical interstitial lung disease (ILD) has not been studied.

71 recognition that interstitial lung disease (ILD) in infants is often distinct from the forms that oc

72 tities that cause interstitial lung disease (ILD) in infants.

73 Interstitial lung disease (ILD) is a common manifestation of systemic sclerosis and

74 RATIONALE: Interstitial lung disease (ILD) is a heterogeneous group of acute and chronic infla

75 Interstitial lung disease (ILD) is a well-known extra-articular manifestation of rh

76 Interstitial lung disease (ILD) is fast approaching chronic obstructive pulmonary d

77 is a progressive interstitial lung disease (ILD) of unknown origin characterized by epithelial cell

78 of more advanced Interstitial Lung Disease (ILD) patterns, few have tackled ILA, which likely preced

79 Rationale: Interstitial lung disease (ILD) represents a major challenge in systemic sclerosis

80 Interstitial lung disease (ILD), a leading cause of morbidity and mortality in rheu

81 y disease (COPD), interstitial lung disease (ILD), and "other." Intensive care unit (ICU) length of s

82 COPD), asthma and interstitial lung disease (ILD), and individual cardiovascular diseases, and evalua

83 ncreased risk for interstitial lung disease (ILD), the risk among relatives of sporadic idiopathic pu

84 or unclassifiable interstitial lung disease (ILD), which is characterised by progressive fibrosis of

85 the aetiology of interstitial lung disease (ILD).

86 s attributable to interstitial lung disease (ILD).

87 e pathogenesis of interstitial lung disease (ILD).

88 in the absence of Interstitial Lung Disease (ILD).

89 velop progressive interstitial lung disease (ILD).

90 ary hemorrhage or interstitial lung disease (ILD).

91 isease (COPD) and interstitial lung disease (ILD).Methods: The multidisciplinary panel created six re

92 10.6; SMR, 3.9), interstitial lung disease (ILD; EAR, 9.7; SMR, 22.1), and adverse events (AEs) rela

93 cess of deaths as a result of heart disease, ILD, infections, AEs, and solid tumors.

94 gression of most interstitial lung diseases (ILD) is unpredictable.

95 Interstitial lung diseases (ILDs) are associated with oxidative stress.

96 ressive fibrotic interstitial lung diseases (ILDs) are characterised by major reductions in quality o

97 Interstitial lung diseases (ILDs) are characterized by injury, inflammation, and sca

98 nal follow-up of interstitial lung diseases (ILDs) at CT mainly relies on the evaluation of the exten

99 ch as asthma and interstitial lung diseases (ILDs), including idiopathic pulmonary fibrosis (IPF) and

100 contiguity (automated interlesion distance [ILD]).

101 roid sizes (CS) and interlandmark distances (ILDs).

102 ns across all ILD cases, as well as distinct ILD subsets, were observed.

103 liver dose (HILD), and injected liver dose (ILD).

104 olliculus (of chinchilla) effectively encode ILDs despite complete decorrelation of left- and right-e

105 Existing ILD registries have had variable findings.

106 CC; Jaipur, India) with MDD, and experienced ILD experts at the Center for ILD (CILD; Seattle, WA) wi

107 Coarseness of fibrosing ILD (P = .011) and IPF diagnosis (P = .016) were indepen

108 ion DPO is common in patients with fibrosing ILD and is significantly more prevalent in patients with

109 ised 892 consecutive patients with fibrosing ILD, including 456 patients with idiopathic pulmonary fi

110 with IPF than in those with other fibrosing ILDs, and thus, computed tomographic signs of DPO may be

111 rosis from non-idiopathic pulmonary fibrosis ILD and used lung function to determine the greatest ris

112 ective implementation of palliative care for ILD will require multidisciplinary participation from cl

113 nd experienced ILD experts at the Center for ILD (CILD; Seattle, WA) with MDD.

114 heumatology (ACR) cohorts were evaluated for ILD.

115 with ILA, 19 (58%) had further evidence for ILD (defined by the combination of imaging findings and

116 lung attenuation are a novel risk factor for ILD hospitalization and mortality.

117 Strikingly elevated SMRs for ILD, infections, and AEs were observed < 1 year after cH

118 ing responsiveness to emerging therapies for ILD.

119 ections from bleomycin-treated mice and from ILD patients.

120 ion were strongly associated with death from ILD.

121 e in fibroblasts and in tissue sections from ILD patients and in lungs of bleomycin-treated mice.

122 , 50% of the subjects with SSc (n = 324) had ILD by HRCT and 46% displayed pulmonary function decline

123 ted in a subset of subjects with HPS who had ILD but not subjects without lung disease or normal cont

124 at proved effective in correctly identifying ILD patients in the training and validation data sets.

125 = 33), patients with alternative idiopathic ILDs (a-ILD; n = 41), and healthy control subjects (n =

126 uish patients with IPF from other idiopathic ILDs.

127 into current prediction models might improve ILD prognostication.

128 In ILD and COPD, descriptors alluding to inspiratory diffic

129 In ILD-lungs with paired biopsies, lower lobes contained mo

130 ial cytokine that induces fibrotic action in ILD fibroblasts (ILDFbs).

131 ydrogenase [COX/SDH]-ratio) was depressed in ILD (median = 0.10,) compared with controls (0.12, p < 0

132 -type mtDNA copies were slightly elevated in ILD (p = 0.088).

133 , a marker of ROS-formation, was elevated in ILD-biopsies (p = 0.044).

134 both trigger and perpetuate ROS-formation in ILD.

135 uced CD44v6-dependent fibroblast function in ILD fibrosis.

136 our understanding of mechanisms involved in ILD and thereby aid in identification of new therapeutic

137 controls (median = 0%) and at high levels in ILD (median = 17%; p < 0.001).

138 outcomes and circulating cytokine levels in ILD.

139 ILD experts, emphasizing the value of MDD in ILD diagnosis.

140 ent predicts TFS and hospitalization risk in ILD and is associated with decreased levels of a key cir

141 Outcomes were assessed in three independent ILD cohorts.

142 2) assess the reversibility of inflammatory ILD following anti-TNF therapy known to resolve TNF-Tg i

143 esting the existence of a highly integrative ILD-coding mechanism.

144 Interestingly, ILD processing in all inferior colliculus cell types (EE

145 case report forms: local site investigators, ILD experts at the National Data Coordinating Center (ND

146 ts with IPF compared with those with non-IPF ILD.

147 between ITDs and ILDs, introducing large ITD-ILD conflicts in some cases.

148 f interaural time and level differences (ITD/ILD), which are the timing and intensity differences of

149 l information was analyzed in terms of ITDs, ILDs, and interaural coherence, both for whole stimuli a

150 Cs between the readers and the deep learning ILD contours ranged from 0.74 to 0.75, whereas the media

151 l differences in the timing (ITD) and level (ILD) of impinging sounds carry critical information abou

152 differences in sound timing (ITD) and level (ILD).

153 ected activity was 3.1 +/- 1.5 GBq, and mean ILD was 143 +/- 49 Gy.

154 onwide, population-based SSc cohort.Methods: ILD was assessed prospectively in the Norwegian SSc (Nor

155 In patients with mild to moderate ILD or COPD with similarly reduced inspiratory capacity,

156 ease-related interstitial lung disease (nCTD-ILD).

157 al and fBOS as persons transplanted for nCTD-ILD.

158 1 fashion to controls undergoing LT for nCTD-ILD.

159 nd 76% compared with 91% and 64% in the nCTD-ILD group, respectively.

160 ioral ILD sensitivity (in humans) and neural ILD sensitivity (in single neurons of the chinchilla aud

161 were poorly concordant in the assessment of ILD.

162 adulthood, allows for study of biomarkers of ILD in a homogeneous population at near-certain risk of

163 ky-Pudlak syndrome (HPS), a genetic cause of ILD in early adulthood, allows for study of biomarkers o

164 care, with no role earlier in the course of ILD, has created a culture of neglect.

165 hic patterns that precede the development of ILD.

166 audit of patients with a prior diagnosis of ILD admitted to the hospital with COVID-19 between March

167 rred for lung transplant with a diagnosis of ILD and is associated with a marked increase in mortalit

168 dication, 52 participants had a diagnosis of ILD during 75,232 person-years (median, 12.2 yr) of foll

169 ly relies on the evaluation of the extent of ILD, without accounting for lung shrinkage.

170 The CT features of ILD in group 1 were always depicted in group 2, with sub

171 ualization and conspicuity of CT features of ILD.

172 < 0.001).Conclusions: An undiagnosed form of ILD may be present in greater than 1 in 6 older first-de

173 The etiology of idiopathic forms of ILD is not understood, making them particularly difficul

174 understanding of several different forms of ILD, including neuroendocrine cell hyperplasia of infanc

175 high molecular and cellular heterogeneity of ILD, common protein regulations are observed, even acros

176 nt strategies.Objectives: Evaluate impact of ILD in a unique, nationwide, population-based SSc cohort

177 classification, diagnosis, and management of ILD in children, focusing on neonates and infants under

178 insight into the etiology and management of ILD worldwide.

179 mpared with the outputs of a simple model of ILD processing with a single free parameter, the duratio

180 We developed an inbred mouse model of ILD using vanadium pentoxide (V2O5), the most common for

181 may be useful as a biomarker for outcome of ILD in subjects with HPS.

182 (P = 0.03).Conclusions: The mere presence of ILD at baseline appears to affect outcome in SSc, sugges

183 e coding can account for the preservation of ILD sensitivity despite even extreme temporal degradatio

184 osis is challenging because of the rarity of ILD and the fact that the presenting symptoms of ILD oft

185 as were associated with an increased rate of ILD hospitalization (adjusted hazard ratio, 2.6 per 1-SD

186 re also associated with an increased rate of ILD-specific death (adjusted hazard ratio, 2.3; 95% conf

187 Twenty participants died as a result of ILD (crude rate, 2.7 per 10,000 person-years).

188 uation areas are associated with the risk of ILD hospitalization and mortality in the general populat

189 We collected samples of ILD tissue (n = 45) and healthy donor control samples (n

190 and the fact that the presenting symptoms of ILD often overlap those of common respiratory disorders.

191 learning-based method to depict worsening of ILD based on lung shrinkage detection from elastic regis

192 wing improvement, stability, or worsening of ILD.

193 l programs caused time-varying distortion of ILDs.

194 ry and inhibitory inputs for the encoding of ILDs, human and animal behavioral ILD sensitivity is rob

195 ittle is known about the clinical profile of ILDs in India.

196 her there are differences among the types of ILDs.

197 The dependence of gain modulation on ILD shown here constitutes a means for space-dependent c

198 Indian origin living in India with new-onset ILD (27 centers, 19 Indian cities, March 2012-June 2015)

199 ty pneumonitis was the most common new-onset ILD in India, followed by CTD-ILD and idiopathic pulmona

200 To characterize new-onset ILDs in India by creating a prospective ILD using multid

201 f home oxygen therapy in adults with COPD or ILD but also highlight the need for additional research

202 nts with COPD (moderate-quality evidence) or ILD (low-quality evidence) with severe chronic resting h

203 nts with COPD (moderate-quality evidence) or ILD (low-quality evidence) with severe exertional hypoxe

204 nalyses that the prevalence of either ILA or ILD differed between the 46 relatives with FPF and the 5

205 sensitivity to parametrically varied ITD or ILD cues was measured using fMRI during spatial and nons

206 orded IC neurons sensitive to either ITDs or ILDs in anesthetized guinea pig, before, during, and fol

207 proved successful in predicting SSc patient ILD status with a high degree of success (>82% correct c

208 we study the synaptic currents that process ILD in vivo and use stimuli in which ILD varies around a

209 indicate increased likelihood of progressive ILD.

210 nset ILDs in India by creating a prospective ILD using multidisciplinary discussion (MDD) to validate

211 ciation between variables of interest and RA-ILD.

212 logic conditions, it exacerbates fibrotic RA-ILD.

213 In contrast to human RA-ILD, anti-TNF treatment significantly alleviated both jo

214 k factors and autoantibodies can identify RA-ILD and if the addition of investigational biomarkers is

215 RA-associated ILD (RA-ILD) exists on a wide spectrum, with variable levels of

216 with rheumatoid arthritis-associated ILD (RA-ILD; n = 33), patients with alternative idiopathic ILDs

217 to elucidate the genesis of inflammatory RA-ILD, we aim to achieve the following: 1) characterize th

218 findings may facilitate identification of RA-ILD at an earlier stage, potentially leading to decrease

219 or clinical scans (51% with a spectrum of RA-ILD) were selected.

220 CD21(+)/CD23(-) B cells in the genesis of RA-ILD, which exist in a previously unknown, reversible, pr

221 nce of clinically evident and subclinical RA-ILD on computed tomography scan in two independent RA co

222 rum of clinically evident and subclinical RA-ILD) and 76 ACR subjects with research or clinical scans

223 r both clinically evident and subclinical RA-ILD.

224 e antibodies was strongly associated with RA-ILD (areas under the curve, 0.88 for BRASS and 0.89 for

225 arthritis (RA), is highly prevalent, yet RA-ILD is underrecognized.

226 leus-encoded COX-subunit-4 (COX2/COX4-ratio; ILD-median = 0.6; controls = 2.2; p < 0.001).

227 c or connective tissue disease (CTD)-related ILD and 13 controls.

228 ar detection of systematic sclerosis-related ILD compared with the reference standard.

229 ess CT images from patients with SSc-related ILD.Supplemental material is available for this article.

230 s with sarcoidosis and drug toxicity-related ILD were excluded.

231 equire spectral cues and lateral RFs require ILDs.

232 were used to compare CS and absolute/scaled ILDs between genotypes.

233 To remove the effect of body size, ILDs were scaled against craniomandibular lengths and CS

234 y that strengthened the response to specific ILDs.

235 SSc-ILD does not share the genetic risk architecture observe

236 SSc-ILD shares similarities with IPF, although clear differe

237 nesis of fibrosis in SSc-associated ILD (SSc-ILD) involves cellular injury, activation/differentiatio

238 Rates of acute rejection were less in SSc-ILD (P = 0.05).

239 provided the MCID estimates for FVC% in SSc-ILD based changes at 12 months from baseline in two clin

240 neumonia pattern is commonly observed in SSc-ILD, whereas IPF is defined by usual interstitial pneumo

241 enetic risk, and distinctive features of SSc-ILD and identification of robust prognostic biomarkers a

242 The course of SSc-ILD is variable, ranging from minor, stable disease to a

243 se state such as the risk or presence of SSc-ILD, the activity of lung involvement and the likelihood

244 ciated with SSc-ILD severity and predict SSc-ILD progression.

245 Risk factors for progressive SSc-ILD include older age, male sex, degree of lung involvem

246 ough appropriately treated patients with SSc-ILD have better chances of stabilization and survival, a

247 eactive protein are both associated with SSc-ILD severity and predict SSc-ILD progression.

248 associated with measurements of subclinical ILD in community-dwelling adults.

249 raphy (CT)-based measurements of subclinical ILD, respectively.

250 imely recognition of children with suspected ILD and initiation of appropriate diagnostic evaluations

251 nostic evaluation of children with suspected ILD.

252 and modeling data collectively suggest that ILD sensitivity depends on binaural integration of excit

253 The ILD contours from the three readers and the deep learnin

254 The ILD-dependent synaptic scaling and gain adjustment allow

255 provides useful information in assessing the ILD status of SSc patients.

256 ntegration potentiates a unique role for the ILD system in spatial hearing that may be of particular

257 red at a lower (P < 0.05) ventilation in the ILD and COPD groups than in control subjects.

258 ach of these measurements was similar in the ILD and COPD groups.

259 ordings from the same neuron showed that the ILD tuning of the spikes was sharper than that of the EP

260 ere were 48 hospitalizations attributable to ILD (crude rate, 6.4 per 10,000 person-years).

261 n auditory cortex believed to be integral to ILD processing (excitatory from one ear, inhibitory from

262 ion of extent of fibrosis (QLF) and of total ILD (QILD) on HRCT.

263 form of the pro-SP-C BRICHOS domain and two ILD-associated mutants.

264 Paradoxically, while typical ILD-sensitive neurons of the auditory brainstem require

265 ts with progressive fibrosing unclassifiable ILD could benefit from pirfenidone treatment, which has

266 rs) had progressive fibrosing unclassifiable ILD, a percent predicted forced vital capacity (FVC) of

267 ts with progressive fibrosing unclassifiable ILD.

268 nts with progressive fibrotic unclassifiable ILD.

269 tic simulation to design, train and validate ILD risk screening tools.

270 oint was met when ILA were extensive or when ILD was diagnosed clinically.

271 We investigated the site where ILD is detected in the auditory system of barn owls, the

272 process ILD in vivo and use stimuli in which ILD varies around a constant average binaural level (ABL

273 cell types are explained by a model in which ILDs are computed within separate frequency channels and

274 pulmonary function declines consistent with ILD progression.

275 f healthy control subjects and patients with ILD (n = 42 in each group).

276 nd Main Results: Data from 349 patients with ILD across Europe were included, of whom 161 were admitt

277 st and during exercise in both patients with ILD and patients with COPD than in control subjects.

278 2.27; 1.39-3.71).Conclusions: Patients with ILD are at increased risk of death from COVID-19, partic

279 Among patients with ILD associated with systemic sclerosis, the annual rate

280 cy and safety of nintedanib in patients with ILD associated with systemic sclerosis.

281 btained from chest CT scans of patients with ILD at baseline evaluation over a 10-year period.

282 sine were markedly elevated in patients with ILD compared with control subjects with receiver operati

283 Furthermore, obese patients with ILD had an elevated risk of death (HR, 2.27; 1.39-3.71).

284 Patients with ILD had greater diaphragmatic activity, whereas patients

285 ectives: To assess outcomes in patients with ILD hospitalized for COVID-19 versus those without ILD i

286 is a predictor of mortality in patients with ILD referred for lung transplantation in an Australian c

287 Consecutive patients with ILD referred or on the waiting list for lung transplanta

288 ter prospective study included patients with ILD with a nondefinite usual interstitial pneumonia patt

289 After matching, patients with ILD with COVID-19 had significantly poorer survival (haz

290 mortality was 49% (79/161) in patients with ILD with COVID-19.

291 ry-mechanical relationships in patients with ILD, patients with COPD, and healthy control subjects (n

292 picuously inaccessible to many patients with ILD.

293 be taken to avoid COVID-19 in patients with ILD.

294 s in the circulating plasma of patients with ILD.

295 e 5-year follow-up HRCT, the proportion with ILD events (endpoint met or radiographic ILA progression

296 patterned spectral cues in combination with ILDs give rise to the topographic map of azimuthal audit

297 x-, and comorbidity-matched controls without ILD.

298 ndertaken and compared with patients without ILD, obtained from the ISARIC4C (International Severe Ac

299 spitalized for COVID-19 versus those without ILD in a contemporaneous age-, sex-, and comorbidity-mat

300 ung bases in patients found to have worsened ILD at visual assessment.