ライフサイエンスコーパス: IM

1 IM density was greatest in the alveolar septa.

2 IM response was strongest at V1 and was least in hV4.

3 IM-MS measurement accuracy was confirmed by measurement

4 IM-MS uniquely shows how within a single UMN population,

5 IM-MS yields collision cross section (CCS, Omega) values

6 ompared to a time scale of hours for the H(2)IMes analogue.

7 of the MCB ring, a pathway to which the H(2)IMes catalysts are highly susceptible.

8 2)(L)(py)(=CH(2)) complexes (L = CAAC or H(2)IMes) revealed bimolecular decomposition of the CAAC der

9 r than indenylidene catalyst M2 (RuCl(2)(H(2)IMes)(PCy(3))(Ind)), and 65x faster than UC (RuCl(2)(C1)

10 a Grubbs third generation precatalyst [(H(2)IMes)(pyr)(2)(Cl)(2)Ru=CHPh] was investigated.

11 on of tertiary hydrosilanes with [CpW(CO)(2)(IMes)](+)[B(C(6)F(5))(4)](-) reveals a fundamentally new

12 The formation of [Ir(H)(2)(IMes)(substrate)(3)]Cl is further linked to the hydrogen

13 ) or 4-methylpyridine (4-MP)) into [Ir(H)(2)(IMes)(substrate)(3)]Cl is monitored by (1)H NMR spectros

14 ylation protocol that employs [Ni(IMes)(2)] (IMes = 1,3-dimesitylimidazoline-2-ylidene) for the radic

15 2-IM of lysosomes in primary skin fibroblasts derived from

16 Chemically resolving lysosomes by 2-IM could enable decoding the mechanistic underpinnings o

17 all this technology two-ion measurement or 2-IM.

18 and Main Results: An average of 2.1 x 10(9) IMs and 1.4 x 10(9) AMs were estimated per right upper l

19 We found that YhdP, an IM protein involved in maintaining the OM permeability b

20 ct than vaccine efficacy on modelled EBV and IM prevalence.

21 DNA was isolated from non-IM and IM separately using laser caption microdissection.

22 upling interface between the OM secretin and IM rings, which is remarkably facilitated by a localized

23 visive gain control models to both self- and IM-term responses within each cortical area indicated th

24 differences were observed between I-T1D and IM-T1D, the tooth displacement and inclination, periodon

25 ied marked differences among NM, TC-TAM, and IM-TAM.

26 type density and distribution between TC and IM in human lung cancer and TAM associations with overal

27 ces in model membranes and shown that TM and IM together reduce the flow of lipids at a region of def

28 terocyclic carbene, such as P (n)BuAd(2) and IMes, can be used as an efficient alternative than the e

29 that specify distinct phenotypes of AMs and IMs and entrain qualitatively different responses to tol

30 y GM-CSF and M-CSF in murine primary AMs and IMs.

31 being retrograde (OM to IM) or anterograde (IM to OM).

32 y to tumor cells was observed, especially at IM.

33 Overall fecundity was marginally greater at IM (increasing/stable pup production) than at NR (decrea

34 s, with M2 TAM predominance, particularly at IM.

35 tes with hs-cTnI measured using the Atellica IM TnIH and ADVIA Centaur TNIH (Siemens Healthineers) as

36 (4)S(4)-R](+) clusters (R = alkyl or benzyl; IMes = 1,3-dimesitylimidazol-2-ylidene) generates R*, ul

37 abilized by cooperative interactions between IM and OM proteins(2,3).

38 n the subresidue-level resolution enabled by IM-MS-coupled carbene footprinting can bridge the gap be

39 similar to, or higher than, those induced by IM injection of QIV.

40 The structures defined in this study by IM-MS/MS agree with those found in the past but use much

41 6)-positive/CD43(+) AMs and CD206(+)/CD43(-) IMs were counted in five distinct anatomical locations u

42 n renal AMPK activation 6-24 hours after CLP/IM.

43 The conversion of [IrCl(COD)(IMes)] (COD = cis, cis-1,5-cyclooctadiene, IMes = 1,3-bi

44 RE homogeneous catalyst [Ir-IMes; [IrCl(COD)(IMes)], (IMes=1,3-bis(2,4,6-trimethylphenyl), imidazole-

45 using a multipass traveling wave (TW) cyclic IM (cIM) device.

46 )(IMes)] (COD = cis, cis-1,5-cyclooctadiene, IMes = 1,3-bis(2,4,6-trimethyl-phenyl)imidazole-2-yliden

47 mice were unilaterally immobilized for 14 d (IM) or immobilized for 14 d followed by 14 d of remobili

48 ion is promoted by both a BCR-ABL-dependent (IM-sensitive) STAT5-mediated pathway and a BCR-ABL-indep

49 238 of the 4501 students (5.3%) developed IM; 6 months later, 55 of the 238 (23%) met criteria for

50 At Time 2 (when they developed IM), the two ME/CFS groups tended to have more autonomic

51 ear (Time 1), identified those who developed IM (Time 2) and followed them for 6 months (Time 3), ide

52 latter group at Time 1 (prior to developing IM) in stress, coping, anxiety or depression, but were d

53 Thirty-eight (66%) patients discontinued IM after a median of 7 (range 1-80) months.

54 catalyst [Ir(H)(2) (eta(2) -pyruvate)(DMSO)(IMes)].

55 ected between sample treatment groups by DPM-IM-MS, many of which were not previously detected with c

56 not previously detected by single-pulse DPM-IM-MS.

57 Employing the DPM-IM-MS method to adherent cells yielded the detection of

58 gth, closed-loop traveling wave (TW)-enabled IM separator positioned orthogonally to the main ion opt

59 ESI-IM-MS reveals the presence of multiple conformers for th

60 Ice Maiden (IM) transantarctic expeditions (IM: N = 6, 61 days, 1700 km; SP-17: N = 5, 67 days, 1750

61 difference in the daily energy expenditure (IM: 4,939 kcal day(-1); SP-17: 6,461 kcal day(-1), p = 0

62 More importantly, CD11c-expressing IMs are sufficient for the induction of acute T(H)2-cell

63 chanistic role for TSLP and CD11c-expressing IMs in the development of acute T(H)2-cell-dependent all

64 s attenuated by ablation of CD11c-expressing IMs or by selective deficiency of TSLP receptor signalin

65 rstitial macrophages (IMs) (CD11c-expressing IMs) that are both necessary and sufficient for TSLP-med

66 ess pericyte quantity and function following IM and RE.

67 in(-) pericyte quantity is reduced following IM (P < 0.05).

68 At day 365, acceptable levels were 40% for IM and 50% for ID 2-dose schedule, and 70% for IM and 60

69 and 50% for ID 2-dose schedule, and 70% for IM and 60% for ID 3-dose schedule.

70 en interaction model, providing evidence for IM promoter methylation in bAM.

71 s and overall density, supporting a role for IMs in smoking-related disease.

72 p) abundance at Isle of May, Firth of Forth (IM).

73 increased tumor suppression compared to free IM, which accumulates in the spleen/liver.

74 n three analytical measurements derived from IM-MS (collision cross section, CCS), mass-to-charge (m/

75 of protein-free membranes reconstituted from IM and OM lipids in vitro from M. smegmatis (Msm) unders

76 (non-IM) and intestinal metaplastic glands (IM).

77 reproducible and efficient analysis of HILIC-IM-MS lipidomics data, we developed an open-source Pytho

78 graphy-ion mobility-mass spectrometry (HILIC-IM-MS) has shown advantages in separating lipids through

79 However, IM-based isomer analysis may be complicated by the prese

80 nstrument is based on a Waters SYNAPT G2-S i IM-MS platform, with the IM separation region modified t

81 l(2)] under irradiation to regenerate [Ni(I)(IMes)(2)Cl] and [Ni(IMes)(2)] for the next catalytic cyc

82 straction from aryl chlorides to give [Ni(I)(IMes)(2)Cl] and aryl radicals.

83 e that light promotes the reaction of [Ni(I)(IMes)(2)Cl] with aryl chlorides generating additional ar

84 ICC-IM are sustained by voltage-independent Ca(2+) influx vi

85 ICC-IM responses to EFS were ablated by inhibiting Ca(2+) st

86 ICC-IM is not coordinated with adjacent ICC-IM in a field of view or even with events from other fir

87 amined the possible relationship between ICC-IM and SWs by recording Ca(2+) transients in mice expres

88 tramuscular interstitial cells of Cajal (ICC-IM) are associated with cholinergic varicosities, sugges

89 tramuscular interstitial cells of Cajal (ICC-IM) exhibit spontaneous Ca(2+) transients manifesting as

90 ar class of interstitial cells of Cajal (ICC-IM).

91 We employed Ca(2+) imaging of colonic ICC-IM in situ, using mice expressing GCaMP6f in ICC to eval

92 Colonic ICC-IM receive excitatory inputs from cholinergic neurons vi

93 Two distinct ICC-IM populations were identified.

94 presence of L-NNA and MRS 2500 enhanced ICC-IM Ca(2+) transients.

95 Enhancing ICC-IM Ca(2+) release and Ano1 activation contributes to exc

96 ce expressing GCaMP6f in ICC to evaluate ICC-IM responses to excitatory neurotransmission.

97 in the IAS where only intramuscular ICC (ICC-IM) are found, however the evidence linking ICC-IM to SW

98 Ca(2+) release in ICC-IM activates Ano1, a Ca(2+) -activated Cl(-) conductance

99 Some of the properties of Ca(2+) in ICC-IM in the colon are similar to the behaviour of ICC loca

100 Firing of Ca(2+) transients in ICC-IM is not coordinated with adjacent ICC-IM in a field of

101 e examined Ca(2+) handling mechanisms in ICC-IM of murine proximal colon expressing GCaMP6f in ICC.

102 Ca(2+) transients in ICC-IM rely on Ca(2+) release from the endoplasmic reticulum

103 ), and NK(1) receptors were enriched in ICC-IM.

104 All classes of ICC (including ICC-IM) express Ca(2+) -activated Cl(-) channels, encoded by

105 are found, however the evidence linking ICC-IM to SWs is limited.

106 on Cav(L) or ANO1; properties typical of ICC-IM mediating neural responses in other gastrointestinal

107 receptor agonists had minimal effects on ICC-IM, whereas neostigmine and carbachol increased Ca(2+) t

108 e)](*-) radical anion, which reduces [Ni(II)(IMes)(2)Cl(2)] under irradiation to regenerate [Ni(I)(IM

109 erating additional aryl radicals and [Ni(II)(IMes)(2)Cl(2)].

110 t to those induced by 15 mug HA injected IM (IM-QIV-15).

111 or tissue (NM), the TC (TC-TAM), and the IM (IM-TAM) were analyzed with RNA-sequencing (RNA-seq).

112 e fate of anticancer drugs such as imatinib (IM) to the tumor site resulting in efficient treatment o

113 neous catalyst [Ir-IMes; [IrCl(COD)(IMes)], (IMes=1,3-bis(2,4,6-trimethylphenyl), imidazole-2-ylidene

114 More importantly, IM loaded H-Dots exhibit lower uptake into the immune sy

115 duction in seroprevalence but an increase in IM cases associated with delayed infection.

116 less effective for improving methylation in IM than in non-IM; thus, these interventions are recomme

117 24a-3 methylation only in non-IM, but not in IM.

118 haracteristics driving behaviors observed in IM separation.

119 lveolar bone density on the pressure side in IM-T1D were similar to that of NG (p > 0.05).

120 Incomplete IM is a strong predictor of GC risk.

121 Lungs from chronic smokers had increased IM numbers and overall density, supporting a role for IM

122 -mediated pathway and a BCR-ABL-independent (IM-resistant) STAT4-mediated pathway.

123 erent to those induced by 15 mug HA injected IM (IM-QIV-15).

124 milar to those induced by 15 mug HA injected IM.

125 er and analyzed using a rapid flow injection-IM-MS method.

126 erals (MM, either organic [OM] or inorganic [IM]) on the immune and antioxidant status, and the expre

127 e inputs from the two eyes (intermodulation [IM] terms).

128 Men received a single 360mg intramuscular (IM) dose of gentamicin and underwent test-of-cure (TOC)

129 rearm (FA); uncoated HD-MAPs; intramuscular (IM) injection of commercially available quadrivalent inf

130 of 6 treatment groups (ID vs intramuscular [IM], 2 vs 3 doses, and controls), rabies neutralizing an

131 3; interferon [IFN]-beta-1a intramuscularly [IM], n = 38; IFN-beta-1a subcutaneously [SC], n = 68; IF

132 The standard SABRE homogeneous catalyst [Ir-IMes; [IrCl(COD)(IMes)], (IMes=1,3-bis(2,4,6-trimethylph

133 and parahydrogen on polarization transfer Ir-IMes catalyst.

134 graphy/high resolution mass spectrometry (LC/IM-HRMS) to quantify 25-hydroxyvitamin D (25OHD) in huma

135 samples shows good agreement between this LC/IM-MS and traditional LC/MS/MS methods.

136 d another that penetrates the inner leaflet (IM).

137 cing experiments were possible by leveraging IM separation, which enabled us to separate and analyze

138 8%, SP-17 = 6.5%; p > 0.05) as was fat loss (IM = 30.4%, SP-17 = 40.4%; p > 0.05).

139 cells to M2 IM-TAM or lower proximity to M1 IM-TAM were linked with poor survival.

140 AM and higher proximity of tumor cells to M2 IM-TAM or lower proximity to M1 IM-TAM were linked with

141 trolling monocytes/interstitial macrophages (IMs) (CD11c-expressing IMs) that are both necessary and

142 Rationale: Interstitial macrophages (IMs) and airspace macrophages (AMs) play critical roles

143 macrophages (AMs), interstitial macrophages (IMs) and lung monocytes from two mouse strains enabled i

144 Interstitial macrophages (IMs) constitute a second major pulmonary macrophage popu

145 e Spear17 (SP-17) and all-female Ice Maiden (IM) transantarctic expeditions (IM: N = 6, 61 days, 1700

146 umor center (TC) versus the invasive margin (IM) are largely unknown.

147 nter of the tumour (CT) and invasive margin (IM), was significantly associated with improved survival

148 They were compared with age-matched IM controls.

149 ffold spanning the bacterial inner membrane (IM) (24-mer ring-forming proteins PrgH and PrgK in the S

150 occurs in the mitochondrial inner membrane (IM) and is executed by phosphatidylserine decarboxylase

151 distinct spatial locations, inner membrane (IM) and outer membrane (OM), thus forming a robust perme

152 rade PL transport causes the inner membrane (IM) to shrink and eventually rupture; characterization o

153 must be transported from the inner membrane (IM) to the outer membrane (OM) through a bridge formed b

154 tidoglycan (PG) layer and an inner membrane (IM)(1).

155 he OM and return them to the inner membrane (IM).

156 Incidental meningiomas (IMs) are the most common intracranial neoplasms, especia

157 ells (CMLSCs) to the drug imatinib mesylate (IM).

158 notype, 35% had an intermediate metabolizer (IM) phenotype, 5% had a poor metabolizer (PM) phenotype,

159 o estimate GC risk by intestinal metaplasia (IM) subtype and anatomic location.

160 stritis (CG, N = 37), intestinal metaplasia (IM, N = 21) or gastric cancer (GC, N = 16) from Mexico a

161 20), or treated with insulin plus metformin (IM-T1D, n = 20).

162 genes harbouring intermediately methylated (IM) promoters (average methylation of 33-66%).

163 (TEC; HK2) were exposed to inflammatory mix (IM), a combination of lipopolysaccharide (LPS) and high

164 tly special interest in native ion mobility (IM) and collision induced unfolding (CIU) mass spectrome

165 The use of ion mobility (IM) as an additional level of separation can aid the cha

166 conformation in the gas phase, ion mobility (IM) coupled to mass spectrometry is an attractive approa

167 focusing (PF)-drift tube (DT)-ion mobility (IM) provides first-principles determination of the CCS o

168 ical techniques, including MS, ion mobility (IM), CD, and FTIR spectroscopy assays.

169 Ion mobility (IM)-based collision-induced unfolding (CIU) has gained i

170 hromatographic separation, and ion mobility (IM)-MS for efficient separation and identification of su

171 trometry (ESI-MS) and nano-ESI-ion mobility (IM)-MS with collision-induced unfolding (CIU), chemical

172 Bodyweight loss was modest (IM = 7.8%, SP-17 = 6.5%; p > 0.05) as was fat loss (IM =

173 athologies such as infectious mononucleosis (IM) and certain cancers.

174 y students develop infectious mononucleosis (IM) annually, and 9-12% meet criteria for ME/CFS six mon

175 ) techniques, namely native ion mobility MS (IM-MS), collision-induced unfolding (CIU), and hydrogen-

176 been updated with the insensitive munition (IM) 2,4-dinitroanisole (DNAN).

177 mbedded alphaHL porelike complexes by native IM-MS without the need to fully strip the detergent mice

178 e exclusion chromatography coupled to native IM mass spectrometry (SEC-CIU).

179 isation ion mobility-mass spectrometry (nESI-IM-MS), we characterize the heterogeneous interactions o

180 ion to regenerate [Ni(I)(IMes)(2)Cl] and [Ni(IMes)(2)] for the next catalytic cycle.

181 ctivation and borylation of N-H bonds by [Ni(IMes)(2)] is essential to install a Bpin moiety at the N

182 ed C-Cl borylation protocol that employs [Ni(IMes)(2)] (IMes = 1,3-dimesitylimidazoline-2-ylidene) fo

183 oup by the oxidative addition product of [Ni(IMes)(2)] and in situ-generated HBpin.

184 EPR studies demonstrate that [Ni(IMes)(2)] undergoes very fast chlorine atom abstraction

185 selective C-H borylation of indoles with [Ni(IMes)(2)] as the catalyst is reported.

186 DNA was isolated from non-IM and IM separately using laser caption microdissection

187 miR-129-2 methylation in non-IM may be a surrogate marker of GC in H. pylori-infected

188 miR-129-2 methylation in non-IM was an independent predictive marker of GC in H. pylo

189 uction of miR-124a-3 methylation only in non-IM, but not in IM.

190 for improving methylation in IM than in non-IM; thus, these interventions are recommended at an earl

191 al glands without intestinal metaplasia (non-IM) and intestinal metaplastic glands (IM).

192 -induced polarization ability of AMs but not IMs.

193 antiapoptotic gene expression in AMs but not IMs.

194 etrospective study to assess the activity of IM: data was collected anonymously from individual patie

195 nt was administered and to administration of IM-QIV-15 or IM-A/Sing-15.

196 For UMNs, comparison of IM-MS results with TEM and N(2) physisorption yields qua

197 ection distributions to allow comparisons of IM-MS data for commonly analyzed proteins.

198 t an early stage prior to the development of IM to prevent GC development.

199 study investigated the long term effects of IM in TGCT.

200 , with additional follow-up, the efficacy of IM in TGCT.

201 entify differences in the natural history of IM after e-HRT exposure.

202 al a therapeutically targetable mechanism of IM resistance in CMLSCs.

203 In total, we demonstrate the potential of IM-MS as a standard approach for the characterization of

204 etion of yhdP from mlaA* reduced the rate of IM transport to the OM by 50%, slowing shrinkage of the

205 experiments, extending the current scope of IM technology.

206 The total number and density of IMs was 36% to 56% greater in the lungs of cigarette smo

207 The local density of IMs was greater in the alveolar septa than in the connec

208 wth and thus altering the natural history of IMs.

209 ion of RDX, suggesting that the reduction of IMs will not be inhibited by cyclic nitramines, but degr

210 s with metastatic TGCT progressed rapidly on IM and were excluded for further analyses.

211 stered and to administration of IM-QIV-15 or IM-A/Sing-15.

212 ctures, which are resolved by (PGC)LC and/or IM, validating the combination of the two methods.

213 gapore/GP1908/2015 H1N1 HA (15 mug/dose); or IM injection of H1N1 HA antigen (15 mug/dose).

214 control) and supplemented with either OM or IM (Fe, Zn, Mn, Cu, and Se).

215 he FA or 15 mug HA to the upper arm (UA), or IM injection of QIV.

216 an attractive alternative to circumvent poor IM resolution.

217 Post-IM fragmentation and computational modeling were used to

218 n separations and for pre-, intra-, and post-IM fragmentation.

219 on primary AMs are not conserved in primary IMs.

220 In responding cases we confirmed prolonged IM activity on TGCT symptoms even after discontinuation,

221 is quadrupole-ion mobility-time-of-flight (Q-IM-TOF) mass spectrometer in particular, by exploiting t

222 c range enhancement (DRE) lens of a Waters Q-IM-TOF, or the exit lens of a transfer multipole of a Th

223 his in vitro biosynthesis coupled with rapid IM-MS analysis workflow represents a promising platform

224 n when compared with any previously reported IM-MS platforms, allowing for comprehensive unfolding of

225 dividuals with corpus (vs antrum-restricted) IM showed an OR of 2.1 (95% CI, 0.7-6.6) for GC.

226 r into the B-H bond of the BH borenium salt [IMes(C(6)F(5))BH](+) followed by deprotonation gave the

227 Sepsis/IM resulted in AKI, increased mortality, and in renal AM

228 Renal AMPK activation in response to sepsis/IM is an adaptive mechanism that protects TEC, organs, a

229 weight change was statistically significant (IM = - 2.5%, SP-17 = + 1.0%; p = 0.05).

230 y were small, but statistically significant (IM = 2,282 kcal day(-1); SP-17 = 3,174 kcal day(-1); p =

231 on mobility-mass spectrometry platform (SLIM IM-MS), in conjunction with serpentine ultralong path wi

232 Ion mobility-mass spectrometry (IM-MS) affords unique advantages for probing the conform

233 on have made ion mobility-mass spectrometry (IM-MS) an increasingly popular approach for the structur

234 m untargeted ion mobility-mass spectrometry (IM-MS) experiments.

235 Ion mobility-mass spectrometry (IM-MS) has become a powerful tool for glycan structural

236 Ion mobility-mass spectrometry (IM-MS) has become an important addition to the structura

237 e drift tube ion mobility-mass spectrometry (IM-MS) instrument and utilizes both an existing ion mult

238 Ion mobility-mass spectrometry (IM-MS) is a rapid, two-dimensional analysis that separat

239 Native ion mobility-mass spectrometry (IM-MS) is capable of revealing much that remains unknown

240 rein, native ion mobility mass spectrometry (IM-MS) is employed to measure the intrinsic dynamic prop

241 (CCSs) from ion mobility mass spectrometry (IM-MS) measurements are routinely compared to computatio

242 Ion mobility-mass spectrometry (IM-MS) measurements showed that folded protein conformat

243 blished from ion mobility mass spectrometry (IM-MS) measurements.

244 Ion mobility-mass spectrometry (IM-MS) provides rapid two-dimensional separation of ions

245 ogether with ion mobility mass spectrometry (IM-MS) to study soluble preamyloid oligomers.

246 using native ion mobility-mass spectrometry (IM-MS) we find that alphaHL simultaneously forms hexamer

247 ric-pressure ion mobility-mass spectrometry (IM-MS), and we demonstrate the analytical capability of

248 try (MS) and ion mobility mass spectrometry (IM-MS).

249 M + H + Na](2+), allowed baseline SLIM SUPER IM resolution for all Abeta epimer sets assessed, while

250 ment (Q-cIM-ToF) also enables complex tandem IM experiments to be performed, which were used to obtai

251 We show that IM resistance of CMLSCs is due, at least in part, to mai

252 We show that IM-MS yields a 2D particle size-mass distribution functi

253 The IM component LptB(2)FG powers the process through a yet

254 ntumor tissue (NM), the TC (TC-TAM), and the IM (IM-TAM) were analyzed with RNA-sequencing (RNA-seq).

255 further compromised and ruptured before the IM during mlaA*-mediated death.

256 fficking and demonstrate that PE made in the IM by Psd1 support the intrinsic functionality of comple

257 Targeted analysis of genes in the IM category confirmed the WGBS observation.

258 Nonetheless, PE synthesis in the IM is critical for cytochrome bc(1) complex (III) functi

259 2-like macrophages in the CT, but not in the IM, and high number of FoxP3(+) Tregs in both locations

260 Increasing the IM resolving power should allow finer structural informa

261 ient import of non-mitochondrial PE into the IM.

262 t to the OM by 50%, slowing shrinkage of the IM and delaying lysis.

263 be achieved by increasing the length of the IM separator.

264 Here, we present a direct comparison of the IM- and LC-separation of O-glycans from porcine gastric

265 etabolism is decreased in personnel with the IM or PM phenotypes as compared to those with the NM phe

266 sporadic or no production in those with the IM or PM phenotypes, provides further evidence for the r

267 aters SYNAPT G2-S i IM-MS platform, with the IM separation region modified to accept a cyclic ion mob

268 .9-682.7, p = 0.02) groups compared with the IM-QIV-15 group (GMT 139.3, 95% CI 79.3-244.5).

269 ately encapsulated and stabilized within the IM rings in the manner of a nanodisc, and to which the P

270 Of the IMs, 78% were located within the alveolar septa, 14% aro

271 affective relations were inferred from their IMs (>2 million messages) and trading performance was me

272 lowed by deprotonation gave the thioxoborane IMes(C(6)F(5))B=S.

273 easurements from seven proteins across three IM-MS configurations, namely, an Agilent 6560 IMQToF, a

274 ty of the Mla system being retrograde (OM to IM) or anterograde (IM to OM).

275 Addition of pyridine donors to [(IMes)(3)Fe(4)S(4)-R](+) clusters (R = alkyl or benzyl; I

276 eport the development of a unique drift tube IM-MS (DTIM-MS) platform, which combines high-energy sou

277 Incomplete-type (vs complete-type) IM at baseline presented higher GC risk (OR, 13.4; 95% C

278 resent work, we aimed at developing a unique IM-MS-based approach for the characterization of mAb sub

279 ography-ion mobility-mass spectrometry (UPLC-IM-MS) method was optimized for fecal samples derived fr

280 Utilizing the UPLC-IM-MS method, we were able to identify dysregulation of

281 Here, we use IM-MS to measure the conformational consequences of char

282 ble to deduce their complete structure using IM arrival times and the m/z of specific fragments.

283 ere obtained, and on a TWIMS Q-TOF utilizing IM-MS software rates up to 33 Hz are demonstrated.

284 to expand the field of protein analysis via IM-MS.

285 Traveling wave IM (TWIM) is an established and expanding technique with

286 instrument features a cyclic traveling-wave IM separator integrated in a quadrupole/time-of-flight m

287 es commonly used to calibrate traveling-wave IM separators (-3% average RSD).

288 statistically significantly associated with IM or GC.

289 This evidence, combined with IM data and results from vacuum molecular dynamics simul

290 ion, is more dynamic and fluid compared with IM and reveal the role of cell wall-associated peptidogl

291 in enhanced humoral responses compared with IM injection with higher HAI geometric mean titres (GMTs

292 r to or significantly enhanced compared with IM injection.

293 .1, 95% CI 254.3-751.3) groups compared with IM-QIV-15 (GMT 82.8, 95% CI 42.4-161.8), p = 0.02, p = 0

294 resent an in vitro biosynthesis coupled with IM-MS strategy for rapid generation and analysis of drug

295 Data with IM terms revealed another form of binocular interaction,

296 thylated promoters, revealed that genes with IM promoters were enriched for immune-related GO categor

297 Among individuals with IM (including indefinite for dysplasia) at baseline, inc

298 We conclude that mining the PDB with IM-MS data is a time-effective way to derive low-resolut

299 th gastritis and isolates from subjects with IM or GC; 12 of these showed a significant correlation w

300 Combined treatment with IM and a PIM inhibitor synergistically increases apoptos