ライフサイエンスコーパス: IML

1 We developed a parser to extract 39 804 IMLs from both well annotated and putative NRPS biosynth

2 y(styrenesulfonate)/poly(ethylenimine) as an IML was initially found to be 3.40%.

3 ork reports the design and fabrication of an IML using a simple solution process.

4 henotypic transfer between IML-deficient and IML-intact mice finds that the Bacteroidales family S24-

5 (A) receptor-mediated innervation of OML and IML interneurons also displayed significant differences

6 Both OML and IML interneurons received a direct excitatory monosynapt

7 rmediolateral cell column (IML) of L5-S1 and IML and medial gray of T13-L2, respectively, was activat

8 ss common pitfalls encountered when applying IML methods to computational biology problems.

9 ing at the inner ML (IML)/(OML) interface as IML sprouts into the denervated zone.

10 ether, our results demonstrate that baseline IML formation and function is independent of inflammasom

11 e models, and call for collaboration between IML and computational biology researchers.

12 Analysis of phenotypic transfer between IML-deficient and IML-intact mice finds that the Bactero

13 d identified a striking relationship between IMLs and the amino acid substrates of their adjacent mod

14 dense in the intermediolateral cell column (IML) and intercalated nucleus, regions containing retrog

15 ocated in the intermediolateral cell column (IML) and lamina X (the central autonomic area), regions

16 d GABA in the intermediolateral cell column (IML) as detected by electron microscopy.

17 eurons of the intermediolateral cell column (IML) at all ages.

18 eurons in the intermediolateral cell column (IML) of L5-S1 and IML and medial gray of T13-L2, respect

19 minals in the intermediolateral cell column (IML) that synapse on SPNs and use the inhibitory neurotr

20 levels of the intermediolateral cell column (IML) were labeled by 4 days.

21 l SPNs in the intermediolateral cell column (IML) were recorded in urethane/chloralose-anesthetized r

22 eurons in the intermediolateral cell column (IML).

23 ojects to the intermediolateral cell column (IML).

24 instead of in the intermediolateral column (IML) of the spinal cord.

25 cation to form the intermediolateral column (IML).

26 ettled to form the intermediolateral column (IML); the rest migrated medially to locations between th

27 ntermediolateral nucleus of the spinal cord (IML).

28 efore propose that incorporating the correct IML is critical when attempting combinatorial biosynthes

29 e substrate cytokines identifies a defective IML in Il18(-/-) mice, but this phenotype is ultimately

30 ts the role of the microbiota in determining IML barrier function.

31 udy thus paves way to develop such efficient IMLs for more efficient tandem solar cells.

32 rent sizes and graphene quantum dot embedded IML.

33 bacterial genomes and established the first IMLs database.

34 -controlled Nlrp6(-/-) , detect a functional IML barrier in all strains.

35 d were especially dense in the ventral horn, IML and medial gray.

36 More than 92% of the identified IMLs connect modules that activate a particular pair of

37 ynthase-ir profiles) or GABA-ir dendrites in IML, and terminals immunoreactive for both VGLUT3 and GA

38 methods, use of knowledge base frameworks in IML development, and recent applications.

39 L interneurons but predominantly shunting in IML interneurons.

40 ically in the ipsilateral intermediolateral (IML) cell column of the spinal cord and several brainste

41 jects to cells within the intermediolateral (IML) cell column of the thoracic cord and the sacral par

42 tatory projections to the intermediolateral (IML) cell column.

43 etic nucleus (SPN) of the intermediolateral (IML) regions of L6-S1 spinal cord segments in rats.

44 8 hours, were transported to the ipsilateral IML in the caudal half of the last cervical and first th

45 and the lateral internal medullary lamina (L-IML).

46 The L-IML group exhibited an intermediate level of impairment.

47 ns of the lateral internal medullary lamina (IML) or ibotenic acid lesions of the lateral intralamina

48 ansparent and conductive intermediate layer (IML).

49 The inner molecular layer (IML) displayed a corresponding volumetric expansion in r

50 of the dentate gyrus inner molecular layer (IML) is a pathophysiological process that may facilitate

51 fibers (MF) into the inner molecular layer (IML) of the fascia dentata (FD).

52 The inner mucus layer (IML) is a critical barrier that protects the colonic epi

53 g the use of interpretable machine learning (IML) to unveil biological insights.

54 We explored whether Inter-Modular Linkers (IMLs) impact the ability of NRPS modules to communicate

55 s with isolated mediastinal lymphadenopathy (IML) are a common presentation to physicians, and medias

56 Consistent with ongoing maturation, IML interneurons displayed lower input resistances and m

57 e located in the outer ML (OML) or inner ML (IML).

58 tion of FAC1 immunostaining at the inner ML (IML)/(OML) interface as IML sprouts into the denervated

59 The recent progress of interpretable ML (IML) in the computer science field meets this urgent nee

60 in developing interpretable models with new IML algorithms that can assist new chemical assessments

61 Rats with ILN, but not IML, lesions were impaired in acquiring an initial and 5

62 e right T4 spinal intermediolateral nucleus (IML) immediately increased ipsilateral brown adipose tis

63 several inflammasomes; however, analysis of IML properties in multiple inflammasome-deficient mice,

64 is review, we focused on the applications of IML in computational toxicology, including toxicity feat

65 The challenges and future directions of IML modeling in toxicology are also discussed.

66 We provide an overview of IML methods and evaluation techniques and discuss common

67 The percentages of IML-projecting neurons containing 5-HT(1A)R-ir were 49%

68 Two subtypes of IML neurons were originally described by Ramon y Cajal,

69 Furthermore, only IML interneurons also received significant synaptic inpu

70 nate immune signaling is thought to regulate IML formation via goblet cell Nlrp6 inflammasome activit

71 nied by a corresponding increase in relative IML volume.

72 R, Matlab and SAS/IML code for implementing lossless data reduction is fre

73 A program written in SAS/IML is available from the authors on request.

74 olabeled for 5-HT(1A)R-ir and 5-HT, and some IML-projecting neurons in the RVLM were doubly immunolab

75 Moreover, some IML-projecting neurons in the PPR and RPa were doubly im

76 correlation between aberrant supragranular (IML) mossy fiber sprouting and increased densities of AM

77 The increases in BAT SNA evoked by T4 IML microinjections of NMDA (12 pmol) were significantly

78 han the response to NMDA alone) following T4 IML microinjections of 5-HT (100 pmol to 2 nmol, but not

79 hydroxytryptamine (5-HT, 2 nmol) into the T4 IML increased BAT SNA (peak: +342% of control) at a long

80 evoked by microinjection of NMDA into the T4 IML was reversed by microinjection of methysergide (600

81 ction of methysergide (600 pmol) into the T4 IML.

82 ction of methysergide (600 pmol) into the T4 IML.

83 iminution of FAC1 staining in the OML as the IML sprouted into the denervated zone and revealed that

84 t migrated medially to locations between the IML and the central canal.

85 lin transgenic mice were located in both the IML and near the central canal.

86 tead of migrating dorsolaterally to form the IML.

87 ndicular to radial glial fibers, to form the IML.

88 microscopy, 54% of the axon terminals in the IML (n = 1,337 terminals) were TTC immunolabeled (TTC(+)

89 with GluR1 subunit protein densities in the IML (R=0.784, P<0.0093).

90 of VAChT-positive cholinergic fibers in the IML after EC damage, along with no change in the OML.

91 that the cells expressing MC4-R mRNA in the IML and DMV were autonomic preganglionic neurons as cell

92 ays post-infection, labeling was seen in the IML and lamina X in T12-L1 segments, and in medullary ra

93 Electron microscopy in the IML and lamina X revealed that these puncta were presyna

94 close apposition to serotonin fibers in the IML and medial gray.

95 ansmission onto SPNs and interneurons in the IML and that A1Rs may play a protective role on neurons

96 The use of Ag-NPs in the IML has been shown to lengthen the life time of electron

97 sities of AMPA GluR1 subunit proteins in the IML of the FD.

98 In the IML of the HS group, despite the losses of granule cells

99 that those AT1R-immunopositive cells in the IML were sympathetic preganglionic neurones, while those

100 esser extent) postsynaptic structures in the IML, as well as the luminal membrane of endothelial cell

101 argets of spiny, granule-like neurons in the IML, termed semilunar granule cells (SGCs).

102 , an infection of GABAergic terminals in the IML.

103 beled with rhodamine beads injected into the IML of adult male rats.

104 ng deficits and that extensive damage to the IML or ILN has no detectable effects on retrograde or an

105 .e., supraspinal neurons that project to the IML) were identified near the ventral medullary surface;

106 sy fiber sprouting, which was limited to the IML, the increased GluR1 stainings were distributed thro

107 gration during migration from the OML to the IML.

108 distinct patterns of infectivity within the IML of thoracolumbar and SPN of lumbosacral segments con

109 We analyzed these IMLs and identified a striking relationship between IMLs

110 l labeling was found throughout the thoracic IML suggesting that the PAG modulates sympathetic functi

111 localized 5-HT(1A)R immunoreactivity (ir) to IML-projecting neurons that were retrogradely labeled wi

112 However, guidelines for using IML in computational biology are generally underdevelope

113 rcrutzia consistently positively covary with IML barrier function.

114 inical trial of 77 consecutive patients with IML from 5 centers between April 2009 and March 2011.

115 edictive value of EBUS-TBNA in patients with IML were 92% (95% CI, 83-95%) and 40% (95% CI, 12-74%),

116 aving initial investigation in patients with IML.

117 rtex, 3) the commissural/associational zone (IML) immediately adjacent to the granule cell layer, and

118 ny other neuropil profiles within this zone; IML staining was rare and restricted to large apical den