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1 ISH analyses confirmed previous findings; EtOH withdrawa
2 ISH and FISH take 3 d to perform, whereas IF/FISH takes
3 ISH and IF revealed SN1 and SN2 expression in the gangli
4 ISH arises more commonly from normal and high-normal BP
5 ISH for precursor 45S and mature 28S rRNA was accomplish
6 ISH performed on human malignant tumors revealed strong
7 ISH risks were higher than in those with high-normal BP
8 ISH risks were similar to those with high-normal BP and
9 ISH shows robust mel1b expression in major nodes of the
10 n or RNA markers, including Calb2 and Nkx2.2 ISH (for the prethalamic eminence, and derivatives of th
11 = 2.0, average HER2 copies >/= 4.0; group 2 (ISH-positive): ratio >/= 2.0, copies < 4.0; group 3 (ISH
12 tive): ratio >/= 2.0, copies < 4.0; group 3 (ISH-positive): ratio < 2.0, copies >/= 6.0; group 4 (ISH
13 gh-normal BP (130 to 139/85 to 89 mm Hg); 3) ISH; 4) isolated diastolic hypertension (SBP <140 mm Hg
14 tive): ratio < 2.0, copies >/= 6.0; group 4 (ISH-equivocal): ratio < 2.0, copies >/= 4.0 and < 6.0; a
16 this study, a novel nonisotopic nucleic acid ISH method using catalyzed signal amplification and colo
20 tive HER2 tests, defined as IHC 0/1+ with an ISH ratio >/= 2.0, in eight pathology centers across Can
22 ol dependence, ex vivo electrophysiology and ISH, provides mechanistic insights into how both chronic
27 imary breast cancer were analyzed by IHC and ISH; HER2 and chromosome 17 centromere (CEP17) counts we
28 ion, we identified and characterized JHF and ISH disease-causing mutations in the capillary morphogen
29 ld-type (WT) controls at 1, 2, and 9 mo, and ISH and quantitative polymerase chain reaction (qPCR) we
33 zed reporter deposition-Ng-autometallography ISH) and a conventional indirect alkaline phosphatase me
36 H-labeled cells was more restricted than AVT ISH labeling and was limited to regions of the preoptic
37 he SQuISH protocol against a riboprobe-based ISH procedure by comparing the mRNA expression levels in
38 e 10-17-fold higher with the riboprobe-based ISH than with the SQuISH procedure and the relative abun
39 ely 1.5-fold higher with the riboprobe-based ISH than with the SQuISH procedure, although the relativ
40 ol for studying in situ hybridization-based (ISH) expression patterns in the Allen Brain Atlas, a gen
41 ole procedure takes only 3 days and, because ISH conditions are the same for each probe tested, allow
42 he quality of each probe is evaluated before ISH using a RNA probe quantification (dot blot) assay.
43 duced mixed expired NO and suggest that both ISH and allergen-induced bronchoconstriction share patho
44 iduals with atopic asthma who underwent both ISH challenge and allergen challenge, and compared these
48 tin receptor gene expression in rat brain by ISH using a probe complementary to mRNA for all leptin r
50 ytic cycle of infection were not detected by ISH; and (4) subsets of neurons were selectively vulnera
57 spectively analyzed RAR-beta mRNA levels (by ISH using a digoxigenin-labeled antisense riboprobe) in
58 ial 16S rRNA expression was also measured by ISH, and the results revealed that there was localizatio
61 centages of hepatocytes were HCV-positive by ISH that correlated with hepatocyte ultrastructural chan
62 ion (HER2 copy number or HER2/CEP17 ratio by ISH based on counting at least 20 cells within the area)
63 ened for trial entry, 40.8% were in ASCO-CAP ISH group 1, 0.7% in group 2; 0.5% in group 3, 4.1% in g
70 eased sensitivity compared with conventional ISH and was shown to be specific for HTLV-1 tax DNA.
74 Both are believed to be allelic disorders; ISH is distinguished from JHF by its more severe phenoty
75 16 positive (p16+), 115 (48%) were HPV16 DNA ISH positive (ISH16+), and 134 (56%) were positive for a
79 publicly available collection of Drosophila ISH images, and show that our method achieves excellent
82 encoding region in situ hybridization (EBER ISH), immunohistochemistry for PD-L1 and HER2, dual-colo
86 lasma EBV-DNA is highly concordant with EBER-ISH in HL and suggest that it may have prognostic utilit
88 available collection of Drosophila embryonic ISH images from the Berkeley Drosophila Genome Project,
90 t SPEX(2), an automatic system for embryonic ISH image processing, which can extract, transform, comp
92 munohistochemistry for p16, and fluorescence ISH for EGFR gene copy number were performed on tissue m
93 gene searches, colorimetric and fluorescent ISH image viewers, graphical displays of ISH, microarray
94 digoxigenin-labeled RNA ISH; RNA fluorescent ISH (FISH); and protein immunofluorescence (IF)-RNA FISH
102 descriptors to capture local statistics from ISH images and used the bag-of-words approach to build i
103 ypt sections double labeled using histone H3 ISH and BrdUrd, 92% of 1572 labeled cells exhibited both
105 red in single-labeled sections by histone H3 ISH tightly correlated with that found by in vivo BrdUrd
107 ER2 status (IHC/ISH), HER2/CEP17 ratio, HER2 ISH signals, HER2 H-score, plasma HER2 (ERBB2) amplifica
110 2% (23 of 95), and 19.0% (27 of 142) and HPV ISH was positive in 6.5% (six of 93), 14.6% (15 of 103),
111 sis (JHF) and infantile systemic hyalinosis (ISH) are autosomal recessive syndromes of unknown etiolo
112 refore, using Ventana in situ hybridisation (ISH), quantitative PCR assays and biomarkers of producti
114 Here, we show, by in situ hybridization (ISH) and by the analysis of transgenic reporter expressi
117 ts distribution using in situ hybridization (ISH) and immunohistochemistry (IHC) combined with light
118 sion were assessed by in situ hybridization (ISH) and immunohistochemistry on tissue microarrays and
120 llel approaches, dual in situ hybridization (ISH) and neurotoxic lesions of DA neurons by using 6-hyd
121 culture, we performed in situ hybridization (ISH) and polymerase chain reaction (PCR) to detect KSHV
123 nd data type [such as in situ hybridization (ISH) and supporting histology, microarray, RNA sequencin
124 stochemistry (IHC) or in situ hybridization (ISH) as a predictor of benefit from anti-HER2 therapy.
125 uate a commercialized in situ hybridization (ISH) assay for detecting human papillomavirus (HPV) DNA,
126 ethods, by DFA, by an in situ hybridization (ISH) assay, specifically designed to detect L. pneumophi
127 ly, real-time PCR and in situ hybridization (ISH) assays confirmed that the tonsil harbors SVA RNA du
128 Real-time RT-PCR and in situ hybridization (ISH) assays confirmed these miRNA expression profiles in
129 culture-independent, in situ hybridization (ISH) assays for the detection of MAC in culture, sputum,
130 ody mRNA patterns via in situ hybridization (ISH) calls for development of accurate and automatic ima
131 he mRNA of a gene via in situ hybridization (ISH) during the development of a Drosophila melanogaster
134 und to be positive by in situ hybridization (ISH) for HSV-1 latency-associated transcripts (LAT), the
137 DNA sequences before in situ hybridization (ISH) for localization or used ISH with radioactively-lab
139 unohistochemistry and in situ hybridization (ISH) for neutrophil and macrophage markers, cell adhesio
140 novel method of mRNA in situ hybridization (ISH) for the detection of transcriptionally active HR-HP
141 s high-resolution 3-D in situ hybridization (ISH) gene expression patterns in multiple developing sta
142 ion and complementary in situ hybridization (ISH) gene expression studies targeting selected genes in
145 NA is undetectable by in situ hybridization (ISH) in 50% of non-small-cell lung cancers (NSCLC).
146 us system (CNS) using in situ hybridization (ISH) in combination with a genetic knock-in approach.
147 Despite the reach of in situ hybridization (ISH) in developmental biology, it is rarely used at scal
149 Detection of RNAs by in situ hybridization (ISH) is a well-established technique that permits the st
152 sing a newly modified in situ hybridization (ISH) method for detecting hepatitis C virus (HCV) RNA.
153 ibe a whole-mount RNA in situ hybridization (ISH) method optimized for detection of the cellular and
154 er, we implemented an in situ hybridization (ISH) method to reveal the spatial distribution of miRNA
157 neity by fluorescence in situ hybridization (ISH) provides additional tissue morphology at single-cel
158 ng, either DNA or RNA in situ hybridization (ISH) staining or DNA-based PCR of suspected tumor biopsy
159 ed a highly sensitive in situ hybridization (ISH) system capable of HCV RNA and ISG mRNA detection in
162 unohistochemistry and in situ hybridization (ISH) to characterize changes in perinatal PR expression
163 restriction, we used in situ hybridization (ISH) to detect the frequency of RNA expression for nine
164 this effect, we used in situ hybridization (ISH) to determine whether leptin alters expression of hy
167 s this issue, we used in situ hybridization (ISH) to measure chemokine and cytokine mRNA expression l
168 tochemistry (IHC) and in situ hybridization (ISH) used in clinical procedures for quantification of t
169 ion was determined by in situ hybridization (ISH) using 35S-labelled riboprobes and immunohistochemis
172 histone H3 mRNA using in situ hybridization (ISH) was assessed as a measure of S-phase cells and comp
174 could be detected by in situ hybridization (ISH) with specific antisense oligonucleotide probes in l
177 ixative of choice for in situ hybridization (ISH), and specific anecdotal cautions interdicting the u
178 immunohistochemistry, in situ hybridization (ISH), and Western and Northern blotting, we found that b
179 hemistry and RNAscope in situ hybridization (ISH), demonstrate the value of protein-level measurement
180 C), western blotting, in situ hybridization (ISH), embryonic culture, DiI labeling, and flow cytometr
181 nglion cells (GCs) by in situ hybridization (ISH), immunofluorescence (IF), and Western blotting.
182 d by a combination of in situ hybridization (ISH), immunofluorescence, and PCR for positive-strand an
183 gy, histomorphometry, in situ hybridization (ISH), immunohistochemistry (IHC), and transmission elect
196 ection of the LATs by in situ hybridization (ISH); (3) transcripts expressed during the lytic cycle o
197 ositive [+] or IHC 2+/in situ hybridization [ISH] negative [-]) tumors account for up to approximatel
198 tumor cell: group 1 (in situ hybridization [ISH]-positive): HER2-to-chromosome 17 centromere ratio >
201 atients with isolated systolic hypertension (ISH), but the effect of treatment of ISH on LV mass is n
205 liquid biopsies, including HER2 status (IHC/ISH), HER2/CEP17 ratio, HER2 ISH signals, HER2 H-score,
206 of the spatial pattern of gene expression in ISH images, enabled by our recently developed [Formula:
208 l gene functions can be extracted from large ISH image databases such as the Allen Brain Atlas 1 and
217 tion-specific PCR in situ hybridization (MSP-ISH), which allows for the methylation status of specifi
224 (HPV) DNA, we compared the ability of a new ISH probe, Inform HPV III (Ventana Medical Systems, Tucs
227 ent ISH image viewers, graphical displays of ISH, microarray and RNA sequencing data, Brain Explorer
233 e results call into question the validity of ISH results derived by the use of other gene loci, such
235 ibroblasts derived from patients with JHF or ISH suggests that CMG2 mutations abrogate normal cell in
236 oportion of non-OP HNSCCs that were p16+ (or ISH+) increased among whites (P = .04 for trend) but not
237 Explorer also allows viewing of the original ISH images referenced from any point in a 3D data set.
241 Also, intracellular amplification by PCR-ISH significantly increased sensitivity compared with co
243 ted by PCR-driven in situ hybridization (PCR-ISH), and the number of viral genomes per cell was estim
244 When evaluated by reverse transcription-PCR-ISH, only a small proportion of experimentally infected
246 e have developed a standardized quantitative ISH (SQuISH) protocol that utilizes multiple radioactive
251 varies: whole-mount, digoxigenin-labeled RNA ISH; RNA fluorescent ISH (FISH); and protein immunofluor
252 this protocol, which is similar to other RNA ISH protocols, but optimized for whole-mount Drosophila
253 Epstein-Barr encoded RNA detection using RNA ISH with fluorescein isothiocyanate-labeled oligonucleot
255 equencing and RNA-in situ hybridization (RNA-ISH) that FOLFIRINOX combination chemotherapy induces a
256 ght-field dual-colour chromogenic and silver ISH assays with an image-based computational workflow (I
258 established a highly sensitive and specific ISH assay for the detection of HBV RNA, DNA, and cccDNA.
277 vaginal mucosa as early as 1 day p.i. by TSA-ISH and in retropharyngeal, tracheobronchial, or externa
278 signal-amplified in situ hybridization (TSA-ISH), and immunohistochemistry between days 1 and 12 pos
281 hybridization (ISH) for localization or used ISH with radioactively-labeled probes to obtain adequate
285 llow-up, younger and middle-aged adults with ISH had higher relative risk for CVD and CHD mortality t
286 men aged 60 years and older at baseline with ISH (systolic blood pressure [BP], > or = 160 mm Hg; dia
291 IHC signal distribution was consistent with ISH results, with transport of the protein to processes,
298 or CVD and CHD mortality risk for those with ISH were 1.23 (95% confidence interval [CI]: 1.03 to 1.4
300 for Black and Hispanic women vs White women; ISH occurred a median of 7.7 years (95% CI, 7.3-8.1 year