ライフサイエンスコーパス: IgG

1 IgG and IgM detection probabilities increase from roughl

2 IgG antibodies cause inflammation and organ damage in au

3 IgG bAb response rates to all 4 primary V1V2 antigens we

4 IgG Fc glycans were characterized in 225 healthy childre

5 IgG seroconversion occurred between day 0 and day 21.

6 IgG titers were greater than either IgM or IgA titers fo

7 IgG-containing ICs that bind to FcgammaR and FcRn induce

8 IgG-like multispecific antibodies with asymmetric constr

9 response rates at month 18 than at month 12: IgG bAb response rates to 1086.C V1V2, 21.0% versus 9.7%

10 allenge with an average of 3253 IgA and 1227 IgG antibody-secreting cells per million peripheral bloo

11 -2 IgG test for detection of anti-SARS-CoV-2 IgG antibodies by testing 3 distinct patient populations

12 cal assays (HTSAs) and the Abbott SARS-CoV-2 IgG assay quantify levels of antibodies that strongly co

13 high levels of agreement among 4 SARS-CoV-2 IgG assays authorized for emergency use, regardless of a

14 uroimmun, and Ortho-Clinical anti-SARS-CoV-2 IgG assays.

15 total antibody and Abbott Alinity SARS-CoV-2 IgG assays; a subset of 55 samples from patients with co

16 Here, we evaluated the Abbott SARS-CoV-2 IgG test for detection of anti-SARS-CoV-2 IgG antibodies

17 T-PCR Diagnostic Panel, Cellex's qSARS-CoV-2 IgG/IgM Rapid Test, and point-of-care tests such as Abbo

18 covery of ~450-900 IgG sequences from ~2,200 IgG-secreting activated human memory B cells, activated

19 ear cell (PBMC) analysis on a subgroup of 26 IgG-negative participants.

20 s of the isotype IgM were found in 29 (46%), IgG were found in 27 (43%), and IgA were found in 27 (43

21 e platform also allowed recovery of ~450-900 IgG sequences from ~2,200 IgG-secreting activated human

22 Two nucleocapsid antibody tests (Abbott IgG and Roche total antibody) and one spike protein anti

23 , and 22 (43.1%) were reactive by the Abbott IgG, Roche total antibody, and Abbott IgM assays, respec

24 ) proportion of preterm infants who achieved IgG antibody against vaccine antigens at concentrations

25 study with 108 post-LT patients and found an IgG seroprevalence of 55.6%.

26 We analyzed IgG repertoire diversity, clonal expansion and somatic h

27 Skewing responses toward IgG(2) and IgG(4) subclasses might be a mechanism to suppress IgE-m

28 iption of the complexity of IgE, IgG(4), and IgG epitope recognition at a global, allergome-wide leve

29 n-specific plasma cells, CD4(+) T cells, and IgG fraction crystallizable glycosylation in murine epid

30 that the Ortho anti-SARS-CoV-2 total Ig and IgG high-throughput serological assays (HTSAs) and the A

31 s, we determined SARS-CoV-2-specific IgA and IgG in sera and mucosal fluids of 2 cohorts, including S

32 Nasal pollen-specific IgA and IgG isotypes are potentially protective within the humor

33 ncrease of SARS-CoV-2-specific serum IgA and IgG titers after symptom onset.

34 ocessing on the immunoglobulin (IgM, IgA and IgG), and cytokine content (IL-6, IL-8, IL-10, and TNF-a

35 6 IU/mL (624 pg/mL) and 14 ng/mL for IgE and IgG antibodies, respectively.

36 e by SLIT resulted in highly diverse IgE and IgG(E) repertoires.

37 consecutive years on circulating IgE(+) and IgG(+) memory B cells and allergen-specific Ig levels.

38 o examine the effects of AIT on the IgE- and IgG subclass-expressing memory B cells.

39 ead-based assay for the detection of IgM and IgG antibodies to B. burgdorferi The BioPlex 2200 Lyme T

40 hey were positive for the SARS-CoV-2 IgM and IgG antibodies.

41 preparations of IVIg were tested for IgM and IgG binding to red blood cells (RBCs) from wild-type (WT

42 who showed high SARS-CoV-2 specific IgM and IgG levels.

43 nes, chemokines and specific humoral IgM and IgG responses.

44 IgA, IgM, and IgG and neutralizing antibody responses were quantified

45 we determine whether ALI induced by LPS and IgG immune complexes is affected by C/EBPgamma.

46 2008 to 2017 with immunoglobulin (Ig) M and IgG tested at diagnosis were classified according to ser

47 Post-IVIG PANDAS sera and IgG-depleted baseline sera did not alter the activity of

48 persistence of Vi-specific IgG in serum and IgG(+) antibody-secreting cells in bone marrow.

49 ol for the discovery/engineering of Fabs and IgGs.

50 Anti-IgG antibody conjugated FITC-doped silica nanoparticles

51 ali hydrolysis of the FITC@SiO(2)-NH(2)-anti-IgG released FITC molecules, leading to an amplified flu

52 Antibody (IgG, IgG3 binding, and neutralizing) and CD4+ T-cell (ex

53 For comparison, antitoxin IgG and NAb were measured in cord blood from 50 mothers

54 29%, MOG-IgG-associated disorder in 5%, AQP4-IgG-seropositive neuromyelitis optic spectrum disorder (

55 nger than MS at 36 (16-65; p=0.046) and AQP4-IgG-NMOSD at 45 (6-72; p=0.006).

56 Sera were tested for AQP4-IgG and MOG-IgG by using a live-cell-based flow cytometr

57 resistant scFv sequences when reformatted as IgGs.

58 s studied using bovine fetuin, asialofetuin, IgG, ribonuclease B, and alpha-1 acid glycoprotein (AGP)

59 These data indicate that low-avidity IgG responses to BPI can arise acutely in response to ba

60 gG, LF2 and BMRF1 IgA) or two (LF2 and BGLF2 IgG) antibodies on dichotomous data were identified as t

61 d signatures with either four (LF2 and BGLF2 IgG, LF2 and BMRF1 IgA) or two (LF2 and BGLF2 IgG) antib

62 entially no inhibition, whereas the bivalent IgG fully inhibits beta-tryptase activity in a hinge-dep

63 Glycosylation on both IgG and FcgammaR impacts their interaction dramatically.

64 from 8 out of 11 MS brain donors is bound by IgG Abs.

65 NA-ncRNA transcriptional signature shared by IgG(+) and IgA(+) swMBCs and distinct from NBCs, while u

66 ollment of 17 patients (LGI1-IgG, 14; CASPR2-IgG, 3) over 34 months, the study was terminated due to

67 recipitation (LIPS) assays, we characterized IgG, IgM, and IgA antibodies to the spike receptor bindi

68 nfliximab (a monoclonal mouse-human chimeric IgG).

69 an endopeptidase able to degrade circulating IgG that is currently being tested in transplant patient

70 Combining IgG and IgM screening identified 4/55 additional samples

71 Common IgG and IgE epitopes were identified between both allerg

72 Thus, CD32a and FcRn coregulate IgG IC-mediated immunity in a manner favoring the CD32aH

73 mic medical center chart review of all CRMP5 IgG-positive (serum titer, >1:240) patients seen between

74 d visual outcomes in a large series of CRMP5 IgG-positive patients to characterize further its clinic

75 wed high specificity for discriminating DENV IgG against antibodies of other infectious disease, incl

76 assified according to serology at diagnosis: IgG negative (-) (nonimmune), IgM+/IgG+ (indeterminate),

77 nd one spike protein antibody test (DiaSorin IgG) were included.

78 dent on FcgammaR activation by the different IgG subclasses.

79 atile, orthogonal and adaptable to different IgG antibodies and can be employed to achieve the target

80 ecific unfolding signatures to differentiate IgG subclasses and provide more confident subclass categ

81 Prior to trypsin digestion, IgG and IgA were enriched simultaneously, followed by a

82 Other discovered IgGs heighten pain indirectly by T-cell-mediated inflamm

83 ID-19 with high anti-receptor binding domain IgG titer convalescent plasma is efficacious in early-di

84 generated being indicative of the anti-drug IgG antibody levels in serum.

85 We hypothesized DSA IgG subclass characteristics, compared to total DSA IgG,

86 class characteristics, compared to total DSA IgG, might correlate with specific histopathological phe

87 PBMCs were collected from 23/26 EBOV IgG-negative participants.

88 on between both plasma anti-RBD and anti-ECD IgG titers and in vitro VN titers.

89 ic adults found 73 individuals with anti-ECD IgG titers of >=1:50 and strong positive correlation wit

90 colonization with GBS induces an endogenous IgG response within 20 days of exposure.

91 ratio of the fold-rise (D0 to D30) in anti-F IgG over the fold-rise in RSV-A-neutralizing antibodies

92 the effects of these differences on FcgammaR-IgG interactions, reporter cell lines expressing common

93 ive/equivocal in 21 (22%) (sixteen IgA, five IgG) versus four positives/equivocal in 102 controls (4%

94 thin the IgG-Fc tail, which is essential for IgG function, shows variable composition in humans.

95 -alpha and IL-2, and provide B cell help for IgG production in an IL-21 and CD40L dependent manner.

96 -pharyngeal PCR testing and immunoassays for IgG antibodies.

97 ally discovered as a transport mechanism for IgG from maternal circulation to fetus.

98 targeted by NAC was selectively required for IgG but not for IgM production.

99 ependent variation and suggesting a role for IgG glycosylation in immunocompetence.

100 mptomatic shedders showed seroconversion for IgG (80%), IgA (78%), and blockade antibodies (87%).

101 t that detected SARS-CoV-2 immunoglobulin G (IgG) and immunoglobulin M (IgM) antibodies was undertake

102 ction by identification of immunoglobulin G (IgG) antibodies against T. gondii embryogenesis-related

103 Immunoglobulin G (IgG) antibodies against the capsular polysaccharide (CPS

104 antibody assay to identify immunoglobulin G (IgG) antibodies reactive with Rickettsia rickettsii.

105 on of J8-specific systemic immunoglobulin G (IgG) antibodies when administered subcutaneously without

106 Mumps virus-specific immunoglobulin G (IgG) antibody responses and mumps virus-neutralizing ant

107 essed for antipneumococcal immunoglobulin G (IgG) antibody titers against the 7 serotypes shared by P

108 However, immunoglobulin G (IgG) can also stimulate antiviral responses through its

109 were predominantly of the immunoglobulin G (IgG) class and targeted the S2 subunit.

110 mediator protein 5 (CRMP5) immunoglobulin G (IgG) has been associated with paraneoplastic optic neuri

111 ifferent concentrations of Immunoglobulin G (IgG) in both phosphate buffered saline (PBS) and spiked

112 nostic efficacy similar to immunoglobulin G (IgG) index and neurofilament light chain (area under the

113 ion leads to a decrease in immunoglobulin G (IgG) production against AAV2/1 and AAV2/9 and this strat

114 lls, which promoted B cell immunoglobulin G (IgG) production.

115 The anti-CIP immunoglobulin G (IgG) was deposited on a silica optical fiber surface pre

116 to quantify the levels of immunoglobulin G (IgG), IgM and IgA antibodies against four SARS-CoV-2 ant

117 x virus, and HCMV-specific immunoglobulin G (IgG), serum markers of inflammation, and mycobacterial a

118 eveloped novel recombinant immunoglobulin G (IgG)-binding luciferase-based signal amplifiers (rILSAs)

119 the persistence of measles immunoglobulin G (IgG).

120 autologous contemporaneous immunoglobulin G (IgG).

121 e longitudinal dynamics of immunoglobulin-G (IgG), immunoglobulin-M (IgM), and in vitro neutralizing

122 ing of antibody human immuno globulin gamma (IgG) interaction with virulence factor of S. aureus, sta

123 so showed significantly decreased glomerular IgG, IgM, and C3 deposits.

124 HCMV IgG level, a surrogate marker of viral activity, was cor

125 of a dose response between magnitude of HCMV IgG with risk of tuberculosis disease.

126 Anti-HER2 IgG was induced by Ad/E2TM or naked pE2TM, both encoding

127 cell depletion, and they produced less HER2 IgG, demonstrating positive regulatory function of NK ce

128 pitalized COVID-19 patients developed higher IgG concentrations and the rate of IgG production increa

129 ved algorithm (n = 687), HemosIL-AcuStar-HIT-IgG was used as unique testing in 566 (82.4%) of 687 cas

130 ally enhanced alternative to [(225)Ac]hu11B6-IgG(1) but offered no improvement of therapeutic efficac

131 [(225)Ac]hu11B6-IgG(3) was a functionally enhanced alternative to [(225)

132 with FG-3019 (HRHF-Rest/FG-3019) or a human IgG as a vehicle control (HRHF-Rest/IgG).

133 labeled secondary antibodies (HRP-anti-human IgG/IgM/IgA mixture).

134 Specific recovery of human IgG, IFN-gamma, and HIV-1 RNA indicate the diagnostic ut

135 was degraded ~3 times more slowly than human IgG antibodies or infliximab (a monoclonal mouse-human c

136 Unlike responses to human IgGs, there was little variation in FcgammaR-mediated re

137 w seroconversion (immunoglobulin (Ig)M, IgA, IgG) in >95% of cases and neutralizing antibody response

138 Total IgA, IgG and aPL were measured with clinical diagnostic kits.

139 allow description of the complexity of IgE, IgG(4), and IgG epitope recognition at a global, allergo

140 tributed to transplacental transport of IgG; IgG selectively enhanced for FcRn binding resulted in en

141 iagnosis: IgG negative (-) (nonimmune), IgM+/IgG+ (indeterminate), or IgM-/IgG+ (waning immunity).

142 isotypes, with successful detection of IgM, IgG and IgA antibody-antigen interactions.

143 nimmune), IgM+/IgG+ (indeterminate), or IgM-/IgG+ (waning immunity).

144 ulture, serum samples for measurement of IgM/IgG levels (n=30), and plasma samples for levels of infl

145 However, immunoglobulin (IgG)-based rabies postexposure prophylaxis (PEP) is expe

146 eveloped SARS-CoV-2-specific immunoglobulin (IgG) antibodies, neutralizing plasma, and memory B and m

147 81%; P < 0.001) for every 2-fold increase in IgG.

148 ted with (111)In-anti-gammaH2AX-TAT, (111)In-IgG-TAT control, or vehicle.

149 (111)In-anti-gammaH2AX-TAT, but not (111)In-IgG-TAT or (18)F-FDG, within the pancreas correlated pos

150 iles and molecular monitoring of AIT-induced IgG responses may enhance the success of AIT.

151 report that Fc engineering of anti-influenza IgG monoclonal antibodies for selective binding to the a

152 chniques have been reported to assess intact IgGs subclasses, with recently special interest in nativ

153 tion, approximately one in 16 persons lacked IgG antibodies.

154 After enrollment of 17 patients (LGI1-IgG, 14; CASPR2-IgG, 3) over 34 months, the study was te

155 For the LGI1-IgG seropositive subgroup, 6 of 8 patients in the IVIG g

156 nt for all patients and the subset with LGI1-IgG.

157 xpression in the lung tissue alleviates LPS-/IgG immune complexes-stimulated acute pulmonary damage t

158 widely used, commercially available measles IgG test platforms using a set of 223 well-characterized

159 e characteristics of tests to detect measles IgG, we compared five widely used, commercially availabl

160 We measured IgG antibody responses to 342 P. vivax proteins in longi

161 and unsolicited reactogenicity; we measured IgG binding, neutralizing antibodies and cellular immune

162 cine type on antibody responses, we measured IgG isotypes against four consensus HIV antigens from 2

163 h reduced systemic contamination, the median IgG measured in OriCol-collected rectal secretions (986

164 sed the performance of the BioPlex 2200 MMRV IgG multiplex flow immunoassay (MFI; Bio-Rad Laboratorie

165 gnosis was MS in 57%, idiopathic in 29%, MOG-IgG-associated disorder in 5%, AQP4-IgG-seropositive neu

166 s in a prospective incident cohort of 74 MOG-IgG positive children with serial MRI scans over a media

167 Sera were tested for AQP4-IgG and MOG-IgG by using a live-cell-based flow cytometry assay.

168 nst myelin-oligodendrocyte glycoprotein (MOG-IgG) have been increasingly recognised as a new type of

169 lent new lesions were detected in 14% of MOG-IgG positive participants, most commonly within the firs

170 hnic differences in clinical profiles of MOG-IgG-associated disorders between East Asian (Japanese) a

171 h) and this early response was free of naive IgG-SCs.

172 xigenic Escherichia coli by maternal natural IgG antibodies against the maternal microbiota when anti

173 higher levels of virus-specific neutralizing IgG that recognized epitopes different from those recogn

174 In addition to neutralizing IgG antibody responses in a protective range, multifunct

175 ov number NCT01248195) were tested for NMDAR IgG antibodies using a live cell-based assay.

176 NMDAR IgGs were not more frequent in subjects who later became

177 was the most common target antigen and NMDAR IgGs were more sensitively detected with live versus fix

178 Notably, IgG against the spike receptor binding domain (RBD) was

179 immunosorbent assay to measure anti-DENV NS1 IgG in sera from DENV-naive or preimmune subjects pre- a

180 tios were similar when the anti-nucleocapsid IgG assay was used alone or in combination with the anti

181 ike (primary analysis) and anti-nucleocapsid IgG assays, and staff members were followed for up to 31

182 0.386; P < .001) than with anti-nucleocapsid IgG avidity (Spearman rho = 0.211; P = .026).

183 ml(-1), 100 ng ml(-1), and 1 mug ml(-1)) of IgG antibody (CR3022) to SARS-CoV-2 in human serum sampl

184 hermore, previously reported associations of IgG Fc glycosylation with age in healthy individuals wer

185 The bivalency of IgG antibodies can increase potency via avidity, but has

186 Additionally, a phenotypic comparison of IgG-SCs presented in the spleen during immunization or a

187 disease also produce high concentrations of IgG.

188 itive percent agreement between detection of IgG and neutralizing titers was >93%.

189 we describe a platform for the detection of IgG anti-drug antibodies that may provide an initial scr

190 ction was associated with the elicitation of IgG against the envelope V2 loop and of envelope-specifi

191 his study, we identified another function of IgG by showing that IgG immune complexes elicit distinct

192 (FcRn) has a key role in the homeostasis of IgG.

193 and clinical importance, the interaction of IgG and FcRn remains not completely comprehended.

194 The kinetics of IgG avidity maturation during SARS-CoV-2 infection was s

195 our weeks following MMR-3 receipt, levels of IgG, anti-vaccine strain, and anti-outbreak strain antib

196 developed an ELISA to assess serum levels of IgG, IgM, and IgA autoantibodies against FceRIalpha and

197 Measurements of IgG and IgA in human rectal secretions are used to evalu

198 r a deeper understanding of the mechanism of IgG-FcRn interaction.

199 ed levels of IgM-anti-FceRIalpha, but not of IgG or IgA against FceRIalpha, were linked to low blood

200 hallmark of MS diagnosis is the presence of IgG Abs, which appear as oligoclonal bands in the cerebr

201 miology study investigates the prevalence of IgG and IgM antibodies to SARS-CoV-2 in Los Angeles Coun

202 Prevalences of IgG antibodies were adjusted using sampling weights and

203 ed higher IgG concentrations and the rate of IgG production increased faster compared to nonhospitali

204 he immunologic study revealed high titers of IgG autoantibodies in serum and cerebrospinal fluid dire

205 h was not linked to increased translation of IgG mRNA, but rather to impairment of autophagy.

206 n contributed to transplacental transport of IgG; IgG selectively enhanced for FcRn binding resulted

207 We will focus on IgG-type antibodies conjugated to spherical AuNPs as the

208 procedure to transform Fc-glycans present on IgG mAbs into two site-specific anchor points for the co

209 cretion, although it is required for optimal IgG production and accumulation of long-lived plasma cel

210 body (anti-HBc) total immunoglobulin (Ig) or IgG, and antibody to hepatitis B surface antigen-but ant

211 ELISA sensitivity for IgA or IgG detection was 67.9% (95% CI, 59.4%-75.6%), increasin

212 crobes (anti-Saccharomyces cerevisiae IgA or IgG, anti-Escherichiacoli outer membrane porin C, anti-C

213 isks of transfer of allergen-specific IgE or IgG responses 24 months post-transplantation.

214 on or a 4-fold rise in virus-specific IgM or IgG antibody titers from acute- and convalescent-phase s

215 ific T-cell but not immunoglobulin (Ig) M or IgG antibody responses.

216 allosensitization by accelerating pathogenic IgG antibody degradation.

217 trast, IFN-gamma response via TCR and plasma IgG specific for Bp were still intact.

218 in vitro and in vivo efficacy of polyclonal IgG against the M. tuberculosis capsular polysaccharide

219 IVIG preparations consisting of pooled IgG are increasingly used for the treatment of autoimmun

220 se in SOT recipients, documenting a positive IgG response in all 7 hospitalized patients.

221 natal mice that lack the capacity to produce IgG are protected from infection with the enteric pathog

222 une diseases acuminates in a proinflammatory IgG fraction crystallizable N-glycosylation pattern and

223 munized for measles do not show a protective IgG titer in the 10 years after vaccination.

224 a surrogate marker of maintaining protective IgG responses, was highly associated with the donor's (3

225 target-molecule-bound mouse IgG1 and rabbit IgG primary antibodies, whereas the bispecific rILSA, MG

226 mutually bound to both mouse IgG1 and rabbit IgG primary antibodies.

227 , and among those with >=10 rats tested, rat IgG prevalence ranged 2%-70% and SEOV RT-PCR positivity

228 cases were significantly associated with rat IgG positivity and RT-PCR positivity (P = .03 and P = .0

229 Post-IVIG serum had reduced IgG binding to CINs, and this reduction correlated with

230 Remarkably, IgG Abs specific for Mpro and other SARS-CoV-2 Ags can a

231 and FcgammaRIIa as the two main responsible IgG receptors for the breaking of immune tolerance of mi

232 a human IgG as a vehicle control (HRHF-Rest/IgG).

233 s due to the OmpD-O-Ag interplay restricting IgG binding, with the pairing of OmpD with its native O-

234 h of the four subclasses of human and rhesus IgG and with Fc variants of IgG1 that enhance binding to

235 responses to different subclasses of rhesus IgG.

236 measured the abundance of anti-SARS-CoV-2 S1 IgG in 16 convalescent COVID-19 patients.

237 Serum IgG testing against potential antigens associated with H

238 rimary series and booster dose and (2) serum IgG geometric mean concentrations after the primary seri

239 er and characterized by a fast rise in serum IgG and neutralizing antibodies.

240 ed reduced efficacy in the presence of serum IgG.

241 Whereas overall RBD-specific serum IgG titers waned with a half-life of 49 days, nAb titers

242 ques had lower titres of SARS-CoV-2-specific IgG antibody levels compared with young macaques.

243 COVID-19 were tested for SARS-CoV-2-specific IgG concentrations.

244 nduced by the bivalent binding of a specific IgG antibody to two antigen-conjugated DNA templating st

245 to ASC upon Ag re-encounter when Ag-specific IgG levels decline.

246 Allergen-specific IgG, which served as a surrogate marker of maintaining p

247 C-II KO mice produced less Coxiella-specific IgG than PIV-vaccinated WT mice.

248 vasive disease, and the role of GBS-specific IgG production in exposed offspring and juvenile mice at

249 IgE may be downregulated by glycan-specific IgG anti-IgE autoantibodies.

250 rolling for the total amount of HSV-specific IgG in the transferred serum.

251 agglutination inhibition, influenza-specific IgG) in children, but not adults.

252 ry immunization did not increase NP-specific IgG.

253 eactivity, and functionality of NS1-specific IgG antibody responses in sera from a phase 2 clinical t

254 significantly increased DENV-2 NS1-specific IgG in naive individuals, which cross-reacted with DENV-

255 provide evidence for functional NS1-specific IgG responses elicited by a candidate dengue vaccine.

256 is proportional to the quantity of specific IgG and of higher magnitude than recovered COVID-19 pati

257 levant molecules in the presence of specific IgG biomarker antibodies.

258 the concentration of SARS-CoV-2 S1-specific IgG is crucial in selecting appropriate convalescent ser

259 ange in seroprevalence of non-stage-specific IgG and anti-TgERP IgG antibodies with human age.

260 lack of long-term persistence of Vi-specific IgG in serum and IgG(+) antibody-secreting cells in bone

261 Virus-specific IgG decayed substantially in most individuals, whereas a

262 ed regimen induced geometric mean anti-spike IgG (63,160 ELISA units) and neutralization (3906) respo

263 alone or in combination with the anti-spike IgG assay to determine baseline status.

264 tronger positive correlation with anti-spike IgG avidity (Spearman rho = 0.386; P < .001) than with a

265 H1/stalk IgG concentration >=215 AU/mL was associated with 90% lo

266 s size and charge variants from the stressed IgG(1).

267 tion between tonsillar TFH-cell and systemic IgG induction after LAIV.

268 nce of non-stage-specific IgG and anti-TgERP IgG antibodies with human age.

269 We found that anti-TgERP IgG persists for substantially longer than previously re

270 mbocytopenia, provides further evidence that IgG is a primary driver in these autoantibody-mediated d

271 Combined, these data indicate that IgG immune complexes potentiate inflammation by human mi

272 fied another function of IgG by showing that IgG immune complexes elicit distinct cytokine profiles b

273 Evidence suggests that IgG-specific processing occurs within the endothelium of

274 The IgG avidity assay used a novel label-free immunoassay te

275 The IgG Fc domain has the capacity to interact with diverse

276 nt of DT (4x minimal cytopathic dose) in the IgG format.

277 1 and AAV2/9 and this strategy modulates the IgG response against AAV cargos.

278 Notably, the titer of the IgG in wild-type animals could be increased by more than

279 Algorithms employing a combination of the IgG responses to N and S antigens result in high diagnos

280 bserved that after recall, appearance of the IgG-SCs within the spleen of immunized mice was fast (<2

281 highly conserved N-linked glycan within the IgG-Fc tail, which is essential for IgG function, shows

282 The glycosylation profile of these IgGs was consistent with a decrease in FcgammaR engageme

283 Thus, IgG molecules with identical constant portions but with

284 n, the gold standard method, and compared to IgG test results.

285 Conversely, FcRn induced responses to IgG IC independently of classical FcgammaR, but optimal

286 Total IgG and IgG1-3 were significantly reduced post-TCZ, wher

287 Total IgG and IgM Ab levels were determined via ELISA.

288 ithout plasma exchange were tested for total IgG and IgG1-4 by ELISA, anti-HLA-total IgG, IgG3 and Ig

289 er the second vaccination, with higher total IgG titres after the tetravalent vaccine than after the

290 otal IgG and IgG1-4 by ELISA, anti-HLA-total IgG, IgG3 and IgG4, and donor-specific antibody by Lumin

291 0.01; scCOVID, p-value<0.001), but not total IgG.

292 ) B cells along with reduced levels of total IgG in B6 mice possibly suggests the initiation of TLR3-

293 ion were assessed using a standardised total IgG ELISA against trimeric SARS-CoV-2 spike protein, a m

294 Skewing responses toward IgG(2) and IgG(4) subclasses might be a mechanism to sup

295 Antipertussis toxin IgG seroconversion occurred in 9 out of 19 colonized par

296 The neonatal Fc receptor (FcRn) transports IgG across barriers, for example, the placenta, enhancin

297 ammaR and FcRn induced FXa activity, whereas IgG-containing ICs with an Fc engineered to be unable to

298 -100% by day 22, after which IgM wanes while IgG remains reliably detectable.

299 Neurological disorders with IgG antibodies against myelin-oligodendrocyte glycoprote

300 nces tumor formation, mice were treated with IgG or anti-F4/80 antibodies to deplete macrophages duri