ライフサイエンスコーパス: Ixodes scapularis

1 % prevalence in Long Island (LI) deer ticks (Ixodes scapularis).

2 xenodiagnosis using the natural tick vector (Ixodes scapularis).

3 cks, including the Lyme disease vector tick, Ixodes scapularis.

4 ocytophila) are both transmitted by the tick Ixodes scapularis.

5 th a cell line isolated from the vector tick Ixodes scapularis.

6 of Lyme disease, is transmitted by the tick Ixodes scapularis.

7 tick cell line, IDE8, derived from embryonic Ixodes scapularis.

8 rickettsial symbiont isolated from the tick Ixodes scapularis.

9 E8, derived from a putative vector, the tick Ixodes scapularis.

10 populations of the blacklegged tick vector, Ixodes scapularis.

11 des list were tested using Aedes aegypti and Ixodes scapularis.

12 bitor present in the saliva of the hard tick Ixodes scapularis.

13 ogens known to infect the black-legged tick, Ixodes scapularis.

14 y louse Pediculus humanus and a tick species Ixodes scapularis.

15 is required for spirochetal colonization of Ixodes scapularis.

16 irochete carried in the "black-legged" tick, Ixodes scapularis.

17 Rabbits or guinea pigs infested with Ixodes scapularis acquire resistance to tick bites, a ph

18 mine whether impaired TLR signaling enhances Ixodes scapularis acquisition of B. burgdorferi, we fed

19 rimary human-biting ticks in this region are Ixodes scapularis, Amblyomma americanum, and Dermacentor

20 quitination machinery is present in the tick Ixodes scapularis and demonstrate that the E3 ubiquitin

21 st southern strains, isolated from the ticks Ixodes scapularis and Ixodes affinis, the cotton rat (Si

22 Ixodes scapularis and Ixodes pacificus are the predomina

23 tic cycle that involves the arthropod vector Ixodes scapularis and mammalian reservoirs.

24 from animals challenged with field-collected Ixodes scapularis and propagated in HL60 cells.

25 tect remnants of blood in blacklegged ticks (Ixodes scapularis) and correctly determine the vertebrat

26 tablished species such as blacklegged ticks (Ixodes scapularis) and their associated pathogens may pr

27 , infecting local populations of deer ticks (Ixodes scapularis) and to test the fit to a neutral IAM.

28 ds to the gut of the intermediate tick host (Ixodes scapularis), and that this interaction is mediate

29 en the microenvironments of the tick vector, Ixodes scapularis, and a mammalian host.

30 ment (OSD) probes to identify the tick host, Ixodes scapularis, and the Lyme disease pathogen, Borrel

31 ivary protein 20 (Salp20) is a member of the Ixodes scapularis anti-complement protein-like family of

32 A. phagocytophilum induces ticks to express Ixodes scapularis antifreeze glycoprotein (iafgp), which

33 omma americanum, Dermacentor variabilis, and Ixodes scapularis are among the principal tick species a

34 rved protein that was discovered recently in Ixodes scapularis as a tick protective antigen and has a

35 hemocytes) from the clinically relevant tick Ixodes scapularis at a single-cell resolution.

36 mice were given cytokines for 10 days after Ixodes scapularis attachment.

37 atural antibodies when its arthropod vector, Ixodes scapularis, begins feeding on a mammalian host.

38 s aegypti and Culex quinquefasciatus), tick (Ixodes scapularis), body louse (Pediculus humanus), kiss

39 and that the typical vector of Lyme disease, Ixodes scapularis, can acquire the spirochetes from infe

40 For example, the highly passaged Ixodes scapularis cell line ISE18 and Ixodes ricinus cel

41 B. burgdorferi in nymphal blacklegged ticks (Ixodes scapularis) collected at the sites the following

42 ber 1994 through December 1995 from the tick Ixodes scapularis, collected from vegetation, and from t

43 ospD expression is generally elevated within Ixodes scapularis compared with mice.

44 Using an Ixodes scapularis-derived cell line, key Argonaute prote

45 us virginianus) determines blacklegged tick (Ixodes scapularis) distribution, which depend on deer fo

46 Extracellular vesicles from Ixodes scapularis enable tick feeding and promote infect

47 When Ixodes scapularis feed on an infected vertebrate host, s

48 nhanced by the presence of B. burgdorferi in Ixodes scapularis, first indicating that spirochaetes mi

49 Additionally, the recent sequencing of the Ixodes scapularis genome and characterization of tick im

50 study, we present the assembly of a 2.23-Gb Ixodes scapularis genome by sequencing two haplotypes wi

51 Out of three encoding genes representing Ixodes scapularis genome paralogs, IrCD1 is the most dis

52 The Ixodes scapularis Genome Project (IGP), the first to seq

53 tein OspB is expressed by spirochetes in the Ixodes scapularis gut.

54 va of the hard tick and Lyme disease vector, Ixodes scapularis, has a repertoire of compounds that co

55 es (PMN) treated with the saliva of the tick Ixodes scapularis have reduced expression of beta(2) int

56 ding the role that nymphal and female ticks, Ixodes scapularis, have in the epidemiology of Lyme dise

57 Here, we show that an Ixodes scapularis homolog of croquemort (Crq), a CD36-li

58 discover that a toxin in blacklegged ticks (Ixodes scapularis) horizontally acquired from bacteria-c

59 immune deficiency (IMD) pathway of the tick Ixodes scapularis How XIAP activates the IMD pathway in

60 nce of the miRNA response of the tick vector Ixodes scapularis in response to Anaplasma phagocytophil

61 rtant than the human biting "bridge" vector, Ixodes scapularis, in maintaining the enzootic spirochet

62 uch as Anopheles gambiae, Aedes aegypti, and Ixodes scapularis influence transmission of diseases suc

63 Ixodes scapularis is a primary vector of tick-borne path

64 The tick Ixodes scapularis is able to feed repeatedly on its natu

65 Ixodes scapularis is the main vector of Lyme disease in

66 In the USA, Ixodes scapularis is the main vector of tick-borne zoono

67 The deer tick, Ixodes scapularis, is a vector of the HGE agent, and the

68 The blacklegged tick, Ixodes scapularis, is an ectoparasitic arachnid and vect

69 The blacklegged tick, Ixodes scapularis, is the predominant arthropod vector i

70 ent (WI-1) and nine of nine mice infected by Ixodes scapularis (Ixodes dammini) tick inoculation of a

71 In Wisconsin and Minnesota, Ixodes scapularis (Ixodes dammini) ticks are the vector

72 Ixodes scapularis larvae successfully acquired Bb(DeltaA

73 Xenodiagnosis using Ixodes scapularis larvae was safe and well tolerated.

74 Ixodes scapularis larvae were fed on EMLA-infected mice,

75 ck transmission with B. burgdorferi-infected Ixodes scapularis larvae.

76 ly, we show that a dae gene in the deer tick Ixodes scapularis limits proliferation of Borrelia burgd

77 Ixodes scapularis long-term blood feeding behavior is fa

78 We investigated whether Ixodes scapularis-mediated host immunity interrupts tran

79 ected into the anal pore of unfed uninfected Ixodes scapularis nymphal ticks.

80 etes to ticks after capillary inoculation of Ixodes scapularis nymphs and the subsequent spirochetal

81 spC expression by B. burgdorferi in infected Ixodes scapularis nymphs as they fed on uninfected mice

82 lp lipoproteins in mice after challenge with Ixodes scapularis nymphs harboring B. burgdorferi 297.

83 protected from infection when infested with Ixodes scapularis nymphs harboring virulent B. burgdorfe

84 Ixodes scapularis nymphs infected with either the B. bur

85 a tick bite and challenged 16 weeks later by Ixodes scapularis nymphs infected with either the same o

86 To assess vlsE expression, Ixodes scapularis nymphs infected with the B. burgdorfer

87 nd challenged either 12 or 16 weeks later by Ixodes scapularis nymphs infected with the same agent.

88 were infested four times with pathogen-free Ixodes scapularis nymphs prior to infestation with nymph

89 The abundance of host-seeking Ixodes scapularis nymphs, the principal vector for the L

90 livary glands of A. phagocytophilum-infected Ixodes scapularis nymphs.

91 sis revealed that antibody generated against Ixodes scapularis OATP cross-reacted with H. longicornis

92 Then, focusing on blacklegged ticks (Ixodes scapularis) on mice (Peromyscus leucopus), we fit

93 In addition, 2 of 14 larval Ixodes scapularis pools, which were attached to two PCR-

94 We have utilized annotations of Ixodes scapularis proteases in gene bank and version 9.3

95 A-lipid nanoparticle vaccine that targets 19 Ixodes scapularis proteins.

96 ft genome for the Rickettsia endosymbiont of Ixodes scapularis (REIS), a symbiont of the deer tick ve

97 Previous studies have demonstrated that both Ixodes scapularis saliva and Borrelia burgdorferi antige

98 In this study, the effects of Ixodes scapularis saliva on cytokine production by bone

99 now describe a feeding-inducible protein in Ixodes scapularis saliva, Salp15, that inhibits CD4(+) T

100 dose or a low dose of POWV, with and without Ixodes scapularis salivary gland extract.

101 Here, we sought to characterize the Ixodes scapularis salivary gland microRNAs (miRNAs) expr

102 Ixodes scapularis salivary protein 20 (Salp20) is a memb

103 Salp15 is an Ixodes scapularis salivary protein that inhibits CD4+ T

104 A. phagocytophilum induces expression of the Ixodes scapularis salp16 gene in the arthropod salivary

105 es of subjects who presented with a definite Ixodes scapularis (Say) tick bite were measured to deter

106 ribe the 2.1 Gbp nuclear genome of the tick, Ixodes scapularis (Say), which vectors pathogens that ca

107 he salivary glands of the black-legged tick, Ixodes scapularis (Say, 1821).

108 nstrate that wild-type animals infested with Ixodes scapularis that produce fewer extracellular vesic

109 he expanding distribution of the tick vector Ixodes scapularis that transmits POWV to humans.

110 Here we report the ability of the tick Ixodes scapularis, the main vector of Lyme disease in th

111 In the Northeast, it is transmitted by Ixodes scapularis, the same vector that transmits Lyme d

112 Rana et al. discovered that Ixodes scapularis, the tick vector of Lyme disease, prod

113 eeking larvae uninfected with the spirochete Ixodes scapularis, thereby perpetuating the agent throug

114 phalitis following a documented bite from an Ixodes scapularis tick and the erythema migrans rash ass

115 ear whether antimicrobial treatment after an Ixodes scapularis tick bite will prevent Lyme disease.

116 nine components to estimate the frequency of Ixodes scapularis tick bites and the resulting incidence

117 agated continuously for over 500 days in the Ixodes scapularis tick cell line IDE8 by using the Garde

118 and OpAG3 were also expressed in an infected Ixodes scapularis tick cell line.

119 iftly upregulated when spirochetes leave the Ixodes scapularis tick gut, migrate to the salivary glan

120 es communication pathway involving a central Ixodes scapularis tick receptor termed Dome1, which acqu

121 agent of human granulocytic anaplasmosis, in Ixodes scapularis tick salivary glands, to detect protei

122 me disease is transmitted by the bite of the Ixodes scapularis tick, which can also transmit Anaplasm

123 m strain, Ap-Variant 1, were obtained in the Ixodes scapularis tick-derived cell line ISE6.

124 infected mice (a reservoir model) to nymphal Ixodes scapularis ticks (a biological vector) and subseq

125 aled that both uninfected larval and nymphal Ixodes scapularis ticks acquired B. burgdorferi as early

126 The mutant cells were able to survive within Ixodes scapularis ticks after a blood meal from naive mi

127 Using Ixodes scapularis ticks and age-matched mice purchased f

128 isingly, sigma54 mutants were able to infect Ixodes scapularis ticks and be maintained for at least 2

129 is an intracellular pathogen transmitted by Ixodes scapularis ticks and causing human granulocytic a

130 were identified from among 99 isolates from Ixodes scapularis ticks and from white-footed mice (Pero

131 valence of Borrelia burgdorferi infection in Ixodes scapularis ticks and Peromyscus sp. mice captured

132 The assay was tested on field-collected Ixodes scapularis ticks and shown to have 100% concordan

133 urgdorferi bbk32 and bbk50 expression within Ixodes scapularis ticks and the murine host, and the eff

134 ssible from inoculated C.B-17 mice to larval Ixodes scapularis ticks and, subsequently, from infected

135 Babesia microti and Borrelia burgdorferi use Ixodes scapularis ticks as vector and Peromyscus leucopu

136 At least 17 of 697 Ixodes scapularis ticks collected in Minnesota or Wiscon

137 PCR analysis of Ixodes scapularis ticks collected in New Jersey identifi

138 s amplified from template DNA extracted from Ixodes scapularis ticks collected in Rhode Island and fr

139 obal transcriptomic landscape inside nymphal Ixodes scapularis ticks during a transmitting bloodmeal.

140 hether the salivary gland extract (SGE) from Ixodes scapularis ticks facilitates the transmission and

141 d to show that spirochetes could be found in Ixodes scapularis ticks feeding on 4 of 10 antibiotic-tr

142 Host-seeking Ixodes scapularis ticks found in the same habitat also w

143 We collected 1232 Ixodes scapularis ticks from 17 east coast sites ranging

144 o 2 strains of DTV that had been detected in Ixodes scapularis ticks from Massachusetts in 1996 and i

145 We collected Ixodes scapularis ticks from regions of suspected patien

146 equencing 279 Powassan viruses isolated from Ixodes scapularis ticks from the northeastern United Sta

147 Ixodes scapularis ticks harbor numerous human pathogens,

148 rospective study of such patients implicated Ixodes scapularis ticks in disease transmission.

149 e Borrelia burgdorferi, it is transmitted by Ixodes scapularis ticks in the northeastern United State

150 Here, we report that Ixodes scapularis ticks infected with either Anaplasma p

151 . phagocytophilum strain HZ in SCID mice and Ixodes scapularis ticks infected with strain NTN-1.

152 In the United States, Ixodes scapularis ticks overwinter in the Northeast and

153 Arthopods such as Ixodes scapularis ticks serve as vectors for many human

154 In this paper we explore the contribution of Ixodes scapularis ticks to the pathogenicity of Borrelia

155 Ixodes scapularis ticks transmit a number of human patho

156 Ixodes scapularis ticks transmit a wide array of human a

157 Ixodes scapularis ticks transmit many pathogens that cau

158 Ixodes scapularis ticks transmit many pathogens, includi

159 Ixodes scapularis ticks transmit multiple pathogens, inc

160 Ixodes scapularis ticks transmit the Lyme disease agent

161 gene expression within the guts of engorging Ixodes scapularis ticks was examined by use of different

162 Nymphal Ixodes scapularis ticks were collected from several site

163 Ixodes scapularis ticks were collected in 2000 and 2001

164 burgdorferi produce OspA in the gut of unfed Ixodes scapularis ticks, and many spirochetes repress Os

165 ten was conjugated to a protein expressed by Ixodes scapularis ticks, called I. scapularis antifreeze

166 teen B. miyamotoi isolates, originating from Ixodes scapularis ticks, rodent and human blood collecte

167 the level of thiamin and its derivatives in Ixodes scapularis ticks, the enzootic vector of Bb, is e

168 ctin in an Ixodes ricinus tick cell line and Ixodes scapularis ticks, to alter the ratio of monomeric

169 ore legs within 210 days after attachment of Ixodes scapularis ticks.

170 e PCR with blood from infected mice and with Ixodes scapularis ticks.

171 rrelia mayonii, are transmitted primarily by Ixodes scapularis ticks.

172 e small mammals that host immature stages of Ixodes scapularis ticks.

173 Lyme disease agent, Borrelia burgdorferi, by Ixodes scapularis ticks.

174 ls exhibited a reduced ability to survive in Ixodes scapularis ticks.

175 d was essential for the persistence of Bb in Ixodes scapularis ticks.

176 ed and in A. americanum, Ixodes affinis, and Ixodes scapularis ticks.

177 Ixodes scapularis transmits the agent of human granulocy

178 The black-legged tick Ixodes scapularis transmits the human anaplasmosis agent

179 omma americanum, 76 Amblyomma maculatum, 383 Ixodes scapularis, two Ixodes brunneus, and 35 Dermacent

180 e to the range expansion of the tick vector, Ixodes scapularis, upon which the causative agent, Borre

181 ized Lyme disease focus with an abundance of Ixodes scapularis vector ticks and the first documentati

182 ain 297 naturally colonized their arthropod (Ixodes scapularis) vector, were maintained in ticks thro

183 Ixodes scapularis was found across the body, although it

184 relia burgdorferi) and its main tick vector (Ixodes scapularis) was studied concurrently and comparat

185 lcatus, Ixodes ricinus, Ixodes pacificus and Ixodes scapularis, was projected using a boosted regress

186 Infected nymphal Ixodes scapularis were allowed to feed individually on m

187 itor (TFPI), Ixolaris, from the ixodid tick, Ixodes scapularis, which has 10 cysteines, and a thrombi

188 For example, ticks such as Ixodes scapularis, which must remain on the host for up

189 a burgdorferi, colonizes the gut of the tick Ixodes scapularis, which transmits the pathogen to verte