ライフサイエンスコーパス: KB cell

1 ine ecoR gene in clonal isolates of HeLa and KB cells.

2 ty for topoisomerase II/DNA complex in human KB cells.

3 d nuclear extracts prepared from PMA-treated KB cells.

4 ons formed intercellular connections between KB cells.

5 dose-dependent inhibition of cell growth in KB cells.

6 to the surface proteins of the oral mucosal KB cells.

7 using folate receptor (FR)-alpha-expressing KB cells.

8 f SCK-folate with the FR was investigated on KB cells.

9 folate-receptor-positive cell lines such as KB cells.

10 the tylophorine analogs, as do the parental KB cells.

11 It was unchanged in proportional of KB cells.

12 was up-regulated by UV in both PC3 cells and KB cells.

13 so inhibited growth of FR-expressing CHO and KB cells.

14 t were not observed with the cytosol from FD-KB cells.

15 d protection did not occur in PAF-R-negative KB cells.

16 nvolved in the attachment of F. nucleatum to KB cells.

17 comparison to ultraviolet-B-treated control KB cells.

18 -receptor-positive cells, but not in control KB cells.

19 extent in both PAF-R-expressing and control KB cells.

20 protein in comparison to UVB-treated control KB cells.

21 uction in the PAF-R-positive but not control KB cells.

22 ids occurred in 293 cells but not in HeLa or KB cells.

23 ermal growth factor receptor in COS-7 and in KB cells.

24 ) and for their cytotoxicity against HFF and KB cells.

25 rTS expression compared with their parental (KB) cells.

26 Total RNA was isolated from KB cells 1 hour after treatment with a PAF-R agonist or

27 Compared with KB cells (a human cell line known for its elevated expre

28 The KB cell, a transformed human cell line, constitutively e

29 LPDII transfection of KB cells, a cell line overexpressing the tumor marker fo

30 to accumulate in multi-vescicular bodies of KB cells after 6 h of incubation.

31 n-regulated in PC3 cells and up-regulated in KB cells after UV exposure.

32 RRM1 decreased in PC3 cells but increased in KB cells after UV treatment.

33 Total RNA from KB cells also protects a 66 bp fragment of an exon 3 rib

34 gonism of IL-8 accumulation did not occur in KB cells, an epithelial cell line that does not support

35 stics of F. nucleatum were also tested using KB cells, an oral epithelial cell line.

36 We further demonstrated the detection of 100 KB cells and 200 pM FR spiked into healthy human blood t

37 most abundant transcripts expressed by human KB cells and lung.

38 h inhibited fusobacterial attachment to both KB cells and S. cristatus, significantly decreased invas

39 e the most abundant transcripts expressed in KB cells and selected normal tissues (including kidney,

40 l]cholesterol cationic liposome complexes in KB cells and were much less cytotoxic.

41 KB cells are know to respond to epidermal growth factor

42 ection into adenovirus type 2-infected human KB cells, as expected.

43 ne of the active compounds were cytotoxic to KB cells at 10(-6) M.

44 s 10 pM of FR and captured 87% of the spiked KB cells at a volumetric throughput of 3 mL/min.

45 soxypodophenazine (14) were found to inhibit KB cells at sub-micromolar concentrations (IC50 = 0.11 +

46 in a shorter half-life of the mRNA in the FR-KB cells by binding to 5' and 3' cis elements, reducing

47 F. nucleatum also promoted invasion of KB cells by other oral streptococci and Actinomyces naes

48 ulate PAF synthesis only in PAF-R-expressing KB cell clones.

49 Inhibition of KB cell colony formation was also observed.

50 The ability of the mutants to invade KB cells compared to the wild type was also determined.

51 efficacy studies using mice inoculated with KB cells demonstrate significantly higher tumor inhibiti

52 Expression of the PAF-R in KB cells did not affect base-line growth or apoptosis, y

53 KB cells displayed the opposite pattern which was revers

54 electron micrographs revealed that infected KB cells exhibited fibrillar protrusions which contained

55 and Western blotting experiments showed that KB cells express MUC1 mRNA and protein.

56 (10 microM in control KB versus 1 microM in KB cells expressing the platelet-activating factor recep

57 of the filaments of microtubule asters in a KB cell extract.

58 ess- or interleukin-1-stimulated epithelial (KB) cells, from bacterial lipopolysaccharide and tumour

59 n, was unable to attach to or invade HGEC or KB cells, further indicating the requirement of bacteria

60 ing affinity studies using FR-alpha-positive KB cells gave half-maximal inhibitory concentrations of

61 expression in human nasopharyngeal carcinoma KB cells grown in folate-deplete and folate-replete medi

62 with a significant inhibitory effect against KB cells (IC50 = 2.7 microg/mL).

63 ug conjugate bound to FA receptor-expressing KB cells in a dose-dependent and saturable manner.

64 e, we show that as soon as ruffles appear on KB cells in response to EGF, their membrane surfaces are

65 esent in the blood), and the total number of KB cells in the sample was estimated to be 98.

66 copy and flow cytometry in FR-overexpressing KB cells, in FR-nonexpressing CHO and HT-1080 cells, and

67 ptors on placental membranes and on ED27 and KB cells incubated at 4 degrees C and blocked the uptake

68 of a dominant-negative PPAR gamma mutant in KB cells inhibited UVB-induced epidermal cell prostaglan

69 aces was relatively low (approximately 8% of KB cell levels).

70 xpression of CD36 in the caveolin-1-negative KB cell line is sufficient for OxLDL-induced internaliza

71 ) resistance/toxicity, sublines from a human KB cell line were made resistant to CPT by continuous se

72 und 29 produces cell death in a HeLa-derived KB cell line, a cellular model of cervical adenocarcinom

73 ted versus a human nasopharyngeal carcinoma (KB) cell line to enable an estimate of the therapeutic i

74 ored with a human oral epidermoid carcinoma (KB) cell line.

75 ate antitumor cytotoxicity against SV-28 and KB cell lines (IC50 approximately 20 microM).

76 th wild type and matched multidrug resistant KB cell lines, and displayed notable selectivity toward

77 was assayed in two multidrug-resistant (MDR) KB cell lines, KB-A1 and KB-V1, selected for resistance

78 f the platelet-activating factor receptor in KB cells lowered the threshold for tert-butyl hydroperox

79 The human KB cell or alpha folate receptor (alpha hFR) is a membra

80 ory cytokines or osmotic shock in epithelial KB cells or embryonic fibroblasts.

81 y of a miR-155 antagonist (antagomir-155) to KB cells overexpressing miR-155 resulted in increased CD

82 ICs) of 2 and 4.5 microg/mL against LoVo and KB cells, respectively.

83 UVB irradiation of KB cells resulted in an increased expression of genes in

84 The presence of the PAF-R in KB cells resulted in augmentation of the production of c

85 UVB irradiation of human epidermal KB cells resulted in both increased levels of reactive o

86 let B irradiation of PAF-receptor-expressing KB cells resulted in significant increases in both inter

87 UVB irradiation of PAF-R-expressing KB cells resulted in significant increases in both TNF-a

88 When expressed in KB cells, SAPK4 was activated in response to cellular st

89 Drug-resistant KB cells selected with cisplatin or oxaliplatin were fou

90 KB cells served as a positive control for AAV infection,

91 In contrast, analogous studies on KB cells showed high levels of receptor binding for all

92 uation of these compounds in L1210, HFF, and KB cells showed that the sugar-modified analogs all were

93 cetemcomitans associated with craters on the KB cell surface and others entering the KB cells through

94 KB cells synthesized platelet-activating factor and the

95 At lower doses (100-200 J/m2) of UVB, only KB cells that expressed the PAF-R became apoptotic.

96 y demonstrated in human epidermoid carcinoma KB cells that UVB irradiation activates PPARgamma via th

97 omplexes with cytosolic proteins from the FR-KB cells that were not observed with the cytosol from FD

98 In KB cells, the total cellular uptake and DNA incorporatio

99 the KB cell surface and others entering the KB cells through apertures with lip-like rims within 30

100 line KB-expressing PAF-Rs (KBP) with that in KB cells transduced with a vector control (KBM).

101 a fluorescent probe were also used to label KB cell tumors in vivo.

102 erence of P. gingivalis wild-type strains to KB cells was completely inhibited by the addition of hyp

103 However, adherence to and invasion of KB cells was not detected with the P. gingivalis fimA mu

104 ell proliferation and increased apoptosis of KB cells were dependent on the presence or absence of th

105 the mutant strain Deltaivi10 recovered from KB cells were eight times lower than those of the wild t

106 Exponentially growing MDR KB cells were exposed to 1400 and 2800 cGy ionizing radi

107 nly activator of SAPK4 that was induced when KB cells were exposed to a cellular stress or stimulated

108 EF2 became dephosphorylated (activated) when KB cells were exposed to anisomycin, an agonist that act

109 Human epithelial KB cells were exposed to protease-active extracellular p

110 gh cell uptake values in FR-alpha-expressing KB cells were found for all 3 radiofolates.

111 While no effect was observed when KB cells were incubated with LPS from Porphyromonas ging

112 tiproliferative effects of compound 8 toward KB cells were protected by excess adenosine but not thym

113 Four nude mice with s.c. inoculation of KB cells were tested for its anticancer activity in vivo

114 and blocked the uptake of [3H]folic acid by KB cells when incubated at 37 degrees C.

115 A-MTX and G5-FA-MTX inhibited cell growth in KB cells, whereas the nontargeted G5-MTX failed to induc

116 s of the receptor), but is very effective in KB cells (which are known to express high levels of the

117 um with placental membranes, ED27 cells, and KB cells, which express the folate receptors.

118 M2 and p53R2, but not hRRM1, bound to p53 in KB cells, which express wild-type p53.

119 dies were conducted with multidrug-resistant KB cells, which harbor extrachromosomal copies of the mu

120 -terminal, and in human oropharyngeal cancer KB cells, which possess wild-type p53.

121 Pretreatment of KB cells with antioxidants vitamin C and N-acetylcystein

122 Treatment of KB cells with the lipid pro-oxidant tert-butyl hydropero

123 Treatment of PAF-receptor-expressing KB cells with the metabolically stable PAF receptor agon

124 Treatment of PAF-R-expressing KB cells with the metabolically stable PAF-R agonist car

125 f N-cadherin was detected after treatment of KB cells with trypsin but not after cell dissociation by

126 evaluated in athymic mice bearing small-size KB cell xenografts (10-100 mg), whereas the intratumor d

127 stigated by autoradiography in 0.3- to 0.6-g KB cell xenografts.