ライフサイエンスコーパス: L-type calcium channel

1 sion of calcium-handling genes (eg, SERCA2a, L-type calcium channel).

2 antagonist at both the NMDA receptor and the L-type calcium channel.

3 e no known selective antagonists of Ca(V)1.3 L-type calcium channel.

4 e the same G406R replacement in the Ca(V)1.2 L-type calcium channel.

5 smembrane Ca(2+) conductance mediated by the L-type calcium channel.

6 rate cardiac repolarization by inhibition of L-type calcium channel.

7 oding the alpha1- and beta2b-subunits of the L-type calcium channel.

8 ity filter, similar to the EEEE locus of the L-type calcium channel.

9 had mutations in genes encoding the cardiac L-type calcium channel.

10 on proteins that control the function of the L-type calcium channel.

11 he recently identified Lp and Ls subtypes of L-type calcium channel.

12 genes encoding subunits of the voltage-gated L-type calcium channel.

13 A(A) receptors is dependent on activation of L-type calcium channels.

14 y AMPA/NMDA receptor-mediated recruitment of L-type calcium channels.

15 d class of antihypertensive drugs that block L-type calcium channels.

16 t contraction and expression and activity of L-type calcium channels.

17 in part via miR-145-dependent regulation of L-type calcium channels.

18 e effects accompanying general antagonism of L-type calcium channels.

19 All E2-BSA-FITC binding neurons expressed L-type calcium channels.

20 t of Erk1/2 on synaptic transmission through L-type calcium channels.

21 cytosis by increasing calcium influx through L-type calcium channels.

22 to induce intracellular calcium flux through L-type calcium channels.

23 lso binds a unique subpopulation of Ca(v)1.2 L-type calcium channels.

24 olely attributable to calcium influx through L-type calcium channels.

25 ransients mediated by high-voltage-activated L-type calcium channels.

26 reflecting activation of NMDA receptors and L-type calcium channels.

27 vated by calcium entry predominantly through L-type calcium channels.

28 om MAPCs (MAPC-SMCs) demonstrated functional L-type calcium channels.

29 primarily by blocking high-voltage-activated L-type calcium channels.

30 ane depolarization and calcium entry through L-type calcium channels.

31 s in the BLC express the Ca(v)1.2 subtype of L-type calcium channels.

32 pamine receptors and impaired by blockers of L-type calcium channels.

33 retreatment decreased subsequent activity of L-type calcium channels.

34 rvival of cultured neurons via activation of L-type calcium channels.

35 expression as strongly as did stimulation of L-type calcium channels.

36 elease is mediated by calcium influx through L-type calcium channels.

37 nel blocker, to eliminate the involvement of L-type calcium channels.

38 may in part be mediated by the activation of L-type calcium channels.

39 entate molecular layer, was not dependent on L-type calcium channels.

40 ux of extracellular Ca2+, presumably through L-type calcium channels.

41 and their activities on cardiac and neuronal L-type calcium channels.

42 xicity is prevented by calcium entry through L-type calcium channels.

43 nt APPsalpha, or by pharmacological block of L-type calcium channels.

44 attenuated by inhibiting cyclooxygenase-2 or L-type calcium channels.

45 extracellular fragment APPsalpha and involve L-type calcium channels.

46 y the secreted APPsalpha-domain and involves L-type calcium channels.

47 harmacologically, CaV1.1e behaves like other L-type calcium channels.

48 mate receptors but blocked by antagonists of L-type calcium channels.

49 ecorated by MG53 in a process coordinated by L-type calcium channels.

50 ite ( approximately 27-130 mum) have reduced L-type calcium channels.

51 pression is thought to require activation of L-type calcium channels, a view based primarily on studi

52 In neonatal rat cardiomyocytes, L-type calcium channel accessory beta-subunit gene knock

53 ce capable of mediating the knockdown of the L-type calcium channel accessory beta-subunit gene was i

54 These findings indicate that knockdown of L-type calcium channel accessory beta-subunit is capable

55 hypothesized that genetic suppression of the L-type calcium channel accessory beta-subunit would modu

56 ate receptor activation, but rather requires L-type calcium channel activation and functional gap jun

57 These findings suggest a scenario in which L-type calcium channel activation is a crucial switch fo

58 tiation in females, whereas in males, either L-type calcium channel activation or calcium release fro

59 tradiol (E2) induced rapid Ca(2+) influx via L-type calcium channel activation, which was required fo

60 naptic depolarization sufficient to activate L-type calcium channels, activation of postsynaptic meta

61 ning mechanical stress-induced activation of L-type calcium channel activity are obscure.

62 L-type calcium channel activity is critical to afterload

63 potentials presumably results from Ca(V)1.3 L-type calcium channel activity.

64 d as novel contributors to the regulation of L-type calcium channel activity.

65 ggering cell growth in a manner dependent on L-type calcium channel activity.

66 The L type calcium channel agonist (+/-)Bay K 8644 has been

67 Application of the L-type calcium channel agonist Bay K 8644 or activation

68 To further verify the mechanism, the L-type calcium channel agonist FPL 64176 was administere

69 ized by chronic treatment with either of the L-type calcium channel agonists FPL 64176 or Bay K 8644.

70 the alpha-interaction domain of the cardiac L-type calcium channel (AID-TAT) on restoring mitochondr

71 Although most L-type calcium channel alpha(1C) subunits isolated from

72 s required for plasma membrane expression of L-type calcium channels alpha 1S (Cav1.1), probably thro

73 for the cardiac isoform of the voltage-gated L-type calcium channel (alpha(1C)) is elevated in colon

74 e 5' flanking region of exon 1b of the human L-type calcium channel alpha1C gene.

75 Voltage-gated CaV1.2 channels (L-type calcium channel alpha1C subunits) are critical me

76 is demonstrated with simulations of a model L-type calcium channel and a mathematical analysis of a

77 Finally, phosphorylation of the L-type calcium channel and phospholamban were found suff

78 The voltage-gated L-type calcium channel and the functionally linked calci

79 Calcium source experiments showed that L-type calcium channels and calcium release from interna

80 tion of I-2 at S43 appears to be mediated by L-type calcium channels and calcium/calmodulin-dependent

81 arlier reports that the AHNAKs are linked to L-type calcium channels and can be phosphorylated by pro

82 primarily due to the blockade of pancreatic L-type calcium channels and insulin resistance on the ce

83 ked proteins, such as Shank3 and subunits of l-type calcium channels and NMDA receptors, and increase

84 ne NGP1-01, a dual action antagonist at both L-type calcium channels and NMDA receptors, was measured

85 presynaptic silent synapses is dependent on L-type calcium channels and protein kinase A (PKA)/PKC s

86 rporates stochastic simulation of individual L-type calcium channels and ryanodine receptor channels,

87 increases macroscopic inward current through L-type calcium channels and slows activation and deactiv

88 e show that the C. elegans SHN-1/Shank binds L-type calcium channels and that increased and decreased

89 studies demonstrated an association between L-type calcium channels and the sigma-1 receptors.

90 release by two different mechanisms: through L-type calcium channels and through an increase in the p

91 ence of defective current densities for Ik1, l-type calcium channel, and Na(+)/Ca(2+) exchanger.

92 smic reticulum Ca2+-release channel, cardiac L-type calcium channel, and Na+/Ca2+ exchanger.

93 ) is required for normal function of cardiac L-type calcium channels, and its up-regulation is associ

94 sion, culture in NGF reduces the activity of L-type calcium channels, and secondarily, the calcium-se

95 en peroxide microdomain signaling stimulates L-type calcium channels, and that this mechanism strongl

96 nk3 and CaMKII were previously shown to bind L-type calcium channels, and we show here that Shank3 al

97 acemaker function, including subunits of the L-type calcium channel, Ank2, and Tbx3.

98 describe the first highly selective Ca(V)1.3 L-type calcium channel antagonist and point to a novel t

99 nt study assessed whether treatment with the L-type calcium channel antagonist nimodipine affects the

100 regarding the effect of the well-established L-type calcium channel antagonist nimodipine.

101 Pretreatment of muscle with nifedipine (L-type calcium channel antagonist) marginally decreased

102 s were inhibited by 20 microM nifedipine, an L-type calcium channel antagonist, and 200 nM omega-agat

103 KII]) via the AC3I peptide and diltiazem, an L-type calcium channel antagonist.

104 (8), a potent and highly selective Ca(V)1.3 L-type calcium channel antagonist.

105 by pretreating the mice with dihydropyridine L type calcium channel antagonists such as nifedipine, n

106 erapamil, D600) and the insensitivity to non-L-type calcium channel antagonists support the conclusio

107 egrees C and found that, at >/=37 degrees C, L-type calcium channels are active at unexpectedly hyper

108 L-type calcium channels are Ca(2+) binding proteins of g

109 Neuronal L-type calcium channels are essential for regulating act

110 Higher levels of L-type calcium channels are in somata/proximal dendrites

111 CaV1 L-type calcium channels are key to regulating neuronal e

112 e details surrounding the mechanism by which L-type calcium channels are privileged in signaling to C

113 dolinium, or nimodipine, which suggests that L-type calcium channels are significant routes of zinc u

114 gene expression, such as CaMKII, Shank3, and L-type calcium channels, are often mutated in multiple n

115 tify ryanodine receptors and plasma membrane L-type calcium channels as druggable targets to intercep

116 eleton as well as the inhibition of at least L-type calcium channels as major reasons for the observe

117 atment with nickel ions, by such blockers of L-type calcium channels as nifedipine, verapamil and dil

118 es and probably influx through voltage-gated L-type calcium channels as well.

119 he plasma membrane sodium calcium exchanger, L-type calcium channels, ATP-sensitive K(+) channels, or

120 of EGFP-VSNL was specific to the actions of L-type calcium channels, because CREB signaling after NM

121 The APD and L-type calcium channel biophysical properties were furth

122 The results are consistent with a model of L-type calcium channel biosynthesis in which there are o

123 Here we report that felodipine, an L-type calcium channel blocker and anti-hypertensive dru

124 Nimodipine, an L-type calcium channel blocker has been shown to reduce

125 -operated calcium entry blocked DIR, but the L-type calcium channel blocker nifedipine did not.

126 (+) (K(ATP)) channel opener diazoxide or the l-type calcium channel blocker nifedipine mimicked the e

127 In sharp contrast, the L-type calcium channel blocker verapamil markedly decrea

128 sing this assay, we identified fendiline, an L-type calcium channel blocker, as a specific inhibitor

129 mias could be terminated by nitrendipine, an l-type calcium channel blocker, but not by the Na channe

130 ting pattern, we applied the benzothiazepine L-type calcium channel blocker, diltiazem.

131 The L-type calcium channel blocker, nifedipine, significantl

132 nd La(3+) but not by Mg(2+) or the classical l-type calcium channel blocker, nitrendipine.

133 ently, diabetic mice with cilnidipine, an N-/L-type calcium channel blocker, showed a reduction in al

134 a group of hearts with diltiazem, a specific L-type calcium channel blocker, to eliminate the involve

135 Instead of its known function as an L-type calcium channel blocker, we found that amlodipine

136 sodilator responses to ketamine, whereas the L-type calcium-channel blocker had no significant effect

137 Other classes of L-type calcium channel blockers did not mislocalize K-Ra

138 First, we observed that the L-type calcium channel blockers nifedipine and verapamil

139 The L-type calcium channel blockers nimodipine and nifedipin

140 al neuroprotective role for centrally acting L-type calcium channel blockers of the dihydropyridine c

141 This study was undertaken to investigate L-type calcium channel blockers of the dihydropyridine c

142 were calcium spikes, blocked by cadmium and L-type calcium channel blockers.

143 h not only required activation of mGluRs and L-type calcium channels but also was bidirectionally mod

144 group I metabotropic glutamate receptors, or L-type calcium channels, but involves adenosine acting a

145 We found that the activation of L-type calcium channels by 2,5-dimethyl-4-[2-(phenylmeth

146 rapidly reduced the barium currents through L-type calcium channels by approximately 70% and shifted

147 orted by data showing that the activation of L-type calcium channels by BAY-K 8644 was unchanged duri

148 Blocking L-type calcium channels by diltiazem (10 microm) signifi

149 A missense mutation in the L-type calcium channel Ca(V)1.2 leads to LQTS in patient

150 rome is caused by a missense mutation in the L-type calcium channel Ca(v)1.2 that is associated with

151 h one of its ultimate effectors, the class C L-type calcium channel Ca(v)1.2.

152 The link between Ca(2+) influx through the L-type calcium channels Ca(v)1.2 or Ca(v)1.3 and glucose

153 ructure of the skeletal muscle voltage-gated L-type calcium channel (Ca(v)1.1; dihydropyridine recept

154 protein kinase A-mediated phosphorylation of L-type calcium channel (Ca(v)1.2) and phospholamban.

155 xyl-terminal cleavage product of the cardiac L-type calcium channel (Ca(V)1.2) autoregulates expressi

156 The proximal C terminus of the cardiac L-type calcium channel (Ca(V)1.2) contains structural el

157 CT2, amino acids 1596-1692) of human cardiac L-type calcium channel (Ca(V)1.2) have been expressed, r

158 L-type calcium channels (Ca(V)1) are involved in diverse

159 Ca(2+) entry through L-type calcium channels (Ca(V)1.2) is critical in shapin

160 hich encodes the pore-forming subunit of the L-type calcium channel, Ca(v)1.4.

161 channels involved mainly phosphorylation of L-type calcium channels, Ca(2+)-dependent inactivation v

162 Consolidation requires signaling through L-type calcium channels, CaM kinase kinase, and the GluA

163 ight regulation of calcium entry through the L-type calcium channel CaV1.2 ensures optimal excitation

164 1C, the alpha1C subunit of the voltage-gated L-type calcium channel Cav1.2, rank among the most consi

165 The L-type calcium channel CaV1.3 constitutes an important c

166 proteins, only otoferlin interacts with the L-type calcium channel Cav1.3, showing a significant dif

167 The CACNA1C-encoded cardiac L-type calcium channel (Cav1.2) is essential for cardioc

168 S resulted from a recurrent, de novo cardiac L-type calcium channel (CaV1.2) mutation, G406R.

169 Calcium influx through the voltage-dependent L-type calcium channel (CaV1.2) rapidly increases in the

170 The activity and expression of L-type calcium channel (Cav1.2), not T-type calcium chan

171 (2+) and alter the properties of the cardiac L-type calcium channel (CaV1.2).

172 In neurons, L-type calcium channels (CaV1.2 and CaV1.3) regulate an

173 This study investigated regulation of L-type calcium channels (Cav1.2b) by acetylcholine (ACh)

174 Here, we study recombinant neuronal L-type calcium channels, CaV1.2 and CaV1.3.

175 s issue of the JCI, Yang et al. focus on the L-type calcium channel complex (LTCC), and their finding

176 Neuronal L-type calcium channels contribute to dendritic excitabi

177 Thus, selectively antagonizing Ca(V)1.3 L-type calcium channels could provide a means of diminis

178 sely, beta2-AR overexpression did not affect L-type calcium channel current (ICaL) under basal condit

179 SKard cardiomyocytes show hyperactivation of L-type calcium channel current that could not be reverse

180 )] to respond most sensitively to changes in L-type calcium channel current.

181 s a calcium-dependent down-regulation of the L-type calcium channel currents by depolarization.

182 cal doses, selectively and potently enhances L-type calcium channel currents in isolated rat ventricu

183 50) for nimodipine block of Ca(V)1.3alpha(1) L-type calcium channel currents is 2.7 +/- 0.3 microm, a

184 e neurons from old mice also exhibit smaller L-type calcium channel currents, providing a plausible m

185 The present study found that L-type calcium channel-dependent LTP in the CA3-CA1 hipp

186 Together, these results show that the L-type calcium channel-dependent survival and NMDA recep

187 protein kinase, internal calcium stores, and L-type calcium channels differ between the sexes.

188 the relative contribution of calcium through L-type calcium channels differs.

189 trix, that the engagement of plasma membrane L-type calcium channels during normal autonomous pacemak

190 strate CALI of connexin43 (Cx43) and alpha1C L-type calcium channels, each tagged with one or two sma

191 calcium-activated potassium channels and an L-type calcium channel (electrical resonance).

192 Recent experiments have shown that L-type calcium channels exhibit circadian rhythms in bot

193 of proteins, gamma(1), is a component of the L-type calcium channel expressed in skeletal muscle.

194 L-type calcium channels expressed in the brain are heter

195 segments of Motifs I-IV of the human cardiac L-type calcium channel, expressed in Xenopus oocytes and

196 h muscle, resulted in a similar reduction of L-type calcium channel expression.

197 Basal and stretch-induced L-type calcium channel expressions were both decreased i

198 Transcripts for the L-type calcium channel gene CACNA1C were consistently de

199 7 exclusion activity in a RBFOX2-target, the L-type calcium channel gene, Cacna1c.

200 The predominant class of L-type calcium channels has a Ca(V)1.2 pore-forming subu

201 urthermore, as pharmacological antagonism of L-type calcium channels has been proposed as a potential

202 nt AMPK phosphorylation, while inhibition of L-type calcium channels has no effect.

203 C, which encodes the Ca(v)1.2 isoform of the L-type calcium channel, have been implicated in both PTS

204 ds was showing the more specific activity on L-type calcium channels, i.e. A7r5 (IC50 = 0.18 +/- 0.02

205 To determine the involvement of the L-type calcium channel in the bursting pattern, we appli

206 a mechanism requiring calcium influx through L-type calcium channels in alphaT3-1 cells and primary r

207 erved role, from fruit flies to mammals, for L-type calcium channels in augmenting motoneuron excitab

208 the present study, we identify a gradient in L-type calcium channels in dendrites of mouse GnRH neuro

209 block of whole cell barium currents through L-type calcium channels in GH4C1 cells show that the com

210 munized mothers exhibited down-regulation of L-type calcium channels in heart.

211 udies attributing an important role to these L-type calcium channels in late onset sporadic Parkinson

212 findings showing that calcium entry through L-type calcium channels in pyramidal cell dendrites in t

213 ts have been used, for example, to implicate L-type calcium channels in the induction of NMDA recepto

214 sed the probability of detecting activity of L-type calcium channels in the T-tubules of ventricular

215 EGFP-VSNL significantly attenuated L-type calcium channel-induced CREB phosphorylation and

216 ations but not [Ca(2+)](c) oscillations, and L-type calcium channel inhibition eliminated [Ca(2+)] os

217 restored normal mRNA levels (blocked by the L-type calcium channel inhibitor, nifedipine).

218 on that is responsive to a specific class of L-type calcium channel inhibitors.

219 The L-type calcium channel is the major calcium influx pathw

220 hthalmia-associated transcription factor and L-type calcium channels is severely affected.

221 The activity of L-type calcium channels is tightly coupled to secretion

222 bunit in a well-characterized voltage-gated, L-type calcium channel, is expressed in hair follicle st

223 Ca(V)1.2, the cardiac L-type calcium channel, is important for excitation and

224 bound to the alpha(1) subunit of the cardiac L-type calcium channel, is required for calcium-dependen

225 equires a specific influx of calcium through L-type calcium channels, JNK activation is independent o

226 that, although the density of intracellular L-type calcium channel labeling remains constant through

227 We have previously shown that the L-type calcium channel (LCC) antagonist nilvadipine redu

228 potential (AP) prolongation (~50%), reduced L-type calcium channel (LCC) current (~33%), reduced out

229 Elevated calcium influx through L-type calcium channels leads to activation of a pathway

230 eightened stimulation, calcium entry through L-type calcium channels leads to activation of the trans

231 Pharmacological blockade of the N- and L-type calcium channel lessens renal injury in kidney di

232 L-type calcium channel (LTCC) and Na(+)/Ca(2+) exchanger

233 l-type calcium channel (LTCC) antagonists have been used

234 G)-like APAs frequently have mutations of an L-type calcium channel (LTCC) CaV1.3.

235 L-type calcium channel (LTCC) current (I(Ca,L)) was meas

236 Ca2+ influx through the L-type calcium channel (LTCC) induces Ca2+ release from

237 nds upon Ca(2+) influx through voltage-gated L-type calcium channels (LTCC) and NFAT translocation to

238 a critical role for APP in the regulation of L-type calcium channels (LTCC) in GABAergic inhibitory n

239 the expression and distribution profiles of L-type calcium channels (LTCCs) and explored their role

240 neuronal activity in naive rats by engaging L-type calcium channels (LTCCs) and that intra-CeA LTCC

241 Cav1.3 voltage-gated L-type calcium channels (LTCCs) are part of postsynaptic

242 Conversely, L-type calcium channels (LTCCs) become involved in gluta

243 CaV1.3 L-type calcium channels (LTCCs) have been a potential ta

244 L-type calcium channels (LTCCs) play important roles in

245 L-type calcium channels (LTCCs) regulate diverse facets

246 Distinct subpopulations of L-type calcium channels (LTCCs) with different functiona

247 c scaffolding protein known to interact with L-type calcium channels (LTCCs), can be specifically coi

248 beta-cell replication in vitro by activating L-type calcium channels (LTCCs).

249 nit [Val-Ser-Asn-Leu (VSNL)] is critical for L-type calcium channels (LTCs) to interact with the sign

250 pha(1) subunit of the cardiac isoform of the L-type calcium channel may be a useful marker of colon c

251 52 protein, as well as antibody targeting of L-type calcium channels may be important in the developm

252 o 39% of neurons by P10-P14, suggesting that L-type calcium channels may contribute to retinocollicul

253 Specifically, L-type calcium channel-mediated augmentation of spike-li

254 r brief depolarization, estradiol attenuated L-type calcium channel-mediated CREB phosphorylation.

255 eta triggered mGluR2/3 signaling, decreasing L-type calcium channel-mediated CREB phosphorylation.

256 L-type calcium channel mRNA was upregulated.

257 iculum Ca(2+) release channel and DHPR is an L-type calcium channel of exterior membranes (surface me

258 ed the impact of mitochondrial regulation of L-type calcium channels on subcellular calcium and react

259 pha1 subunit expression (also referred to as L-type calcium channels or alpha1S pore-forming subunits

260 neuronal activity and enhanced by disrupting L-type calcium channels or elevating cAMP.

261 In skeletal muscle, L-type calcium channels (or dihydropyridine receptors, D

262 little is known about mechanisms that enable L-type calcium channel participation in neurotransmitter

263 rief input train.SIGNIFICANCE STATEMENT CaV1 L-type calcium channels play a key role in regulating th

264 L-type calcium channels play only a minor role in basal

265 cium release, and verapamil, an inhibitor of L-type calcium channels, preferentially affects T1 B cel

266 ium chelators or inhibitors of voltage-gated L-type calcium channels prevented mitochondrial degradat

267 relative to littermate controls, and alpha1C L-type calcium channel protein levels were significantly

268 hibitors of advanced glycation end products, L-type calcium channels, protein kinase C, Rho-kinase, a

269 intracellular Ca2+ triggers inactivation of L-type calcium channels, providing negative Ca2+ feedbac

270 ound that clonidine interacts with sodium or L-type calcium channels, reduces calcium influx into neu

271 L-type calcium channels regulate a diverse array of cell

272 uge scaffold protein, AHNAK1, interacts with L-type calcium channels, regulates Ca2+ influx, and defe

273 o nucleus signalling, mediated via NMDAR and L-type calcium channels, results in rapid FOXP1 deSUMOyl

274 egulated, whereas the levels of microRNA-29, L-type calcium channel, sarco/endoplasmic reticulum calc

275 calibrated hMSC PS effects on cardiomyocyte L-type calcium channel/sarcoendoplasmic reticulum calciu

276 Accelerated L-currents originated from L-type calcium channels since they were completely block

277 ession and protein levels for calsequestrin, L-type calcium channel, sodium-calcium exchanger, phosph

278 mutation in zebrafish disrupts the alpha1 C L-type calcium channel subunit (C-LTCC).

279 genes ankyrin-3 (ANK3) and voltage-dependent L-type calcium channel subunit beta-3 (CACNB3) as direct

280 Ca(v)1.3 L-type calcium channels sustain the pacemaker current, a

281 sarcomere assembly, whereas mutations in the L-type calcium channel that abort calcium entry do not p

282 electrophysiological evidence implicating an L-type calcium channel that modulates glutamate-induced

283 T-tubules are rich in L-type calcium channels, therefore our work might also p

284 tion mutations in genes encoding the cardiac L-type calcium channel to be associated with a familial

285 kinase Src, and the Calalpha2 subunit of the l-type calcium channel to trigger rapid calcium (Ca(2+))

286 with PDZ domain proteins, are necessary for L-type calcium channels to effectively activate CREB and

287 transgenic mouse with an increased number of L-type calcium channels to identify the role of an incre

288 tective agent by interacting with sodium and L-type calcium channels to reduce the influx of these io

289 eration was antagonized by the voltage-gated L-type calcium channel (VGLCC) blocker nifedipine, consi

290 Voltage-gated L-type calcium channels (VLCC) are distributed widely th

291 ling, which is independent of influx through L-type calcium channels, was not affected by Dicer KO.

292 Because gadolinium can inhibit both SACs and L-type calcium channels, we perfused a group of hearts w

293 Pharmacological agents selective for L-type calcium channels were employed to assess the role

294 antagonists support the conclusion that only L-type calcium channels were present.

295 neurons by enhancing calcium influx through L-type calcium channels, whereas NMDA receptor-mediated

296 ming alpha(1C) subunit of Ca(v)1.2 channels (L-type calcium channels), whose promoter has 2 binding s

297 Patch clamp analysis revealed increased L-type calcium channel window current, slow decay time a

298 L-type calcium channels with a Ca(V)1.3 pore-forming sub

299 Reducing calcium influx through L-type calcium channels with nicardipine also blocked re

300 KP4 is shown to specifically block L-type calcium channels with weak voltage dependence to