ライフサイエンスコーパス: LDL-receptor related protein

1 low density lipoprotein (LDL) receptors and LDL receptor related protein.

2 om type I collagen alpha chain, albumin, and LDL receptor-related protein.

3 nes, such as scavenger receptor type B-I and LDL receptor-related protein.

4 the LDL, which was mediated partially by the LDL receptor-related protein.

5 gion also shown to interact with heparin and LDL receptor-related protein.

6 nhibitor of apoE receptors, particularly the LDL-receptor-related protein.

7 or degraded via the TFPI endocytic receptor, LDL-receptor-related protein.

8 We recently observed that the LDL receptor-related protein 1 (LRP-1) is tyrosine phosp

9 vity but required its membrane receptor, the LDL receptor-related protein 1 (LRP-1).

10 vity but required its membrane receptor, the LDL receptor-related protein 1 (LRP-1).

11 sing a haploid genetic screen, we identified LDL receptor-related protein 1 (LRP1) as a host cell rec

12 LDL receptor-related protein 1 (LRP1) is a highly modula

13 The LDL receptor-related protein 1 (LRP1) is a large endocyt

14 The LDL receptor-related protein 1 (LRP1) is a large endocyt

15 The LDL receptor-related protein 1 (LRP1) is a multifunction

16 Recent studies have shown that the LDL receptor-related protein 1 (LRP1) is a physiological

17 rapid clearance of free Abeta40/42 from the LDL receptor-related protein 1 (LRP1) to the VLDL recept

18 epatic clearance of fVIII is mediated by the LDL receptor-related protein 1 (LRP1), a member of the L

19 ell biology techniques, we report that LRP1 (LDL receptor-related protein 1), a member of the LDL rec

20 igration through the surface receptor LRP-1 (LDL receptor-related protein 1)/CD91.

21 Interestingly, unlike LDL receptor-related protein 1, SORL1 binds tau at both

22 hat tPA induces Tyr(4507) phosphorylation of LDL receptor-related protein 1, which in turn leads to t

23 ioma cells, while overexpression of SORL1 in LDL receptor-related protein 1-deficient Chinese hamster

24 nterstitial fibroblast proliferation through LDL receptor-related protein 1-mediated beta1 integrin a

25 ndent of its protease activity, but required LDL receptor-related protein 1.

26 tion of the cytoplasmic tail of its receptor LDL receptor-related protein 1.

27 identified a contribution of the annexin A6/LDL receptor-related protein 1/thrombospondin 1 (ANXA6/L

28 We identify low-density lipoprotein (LDL) receptor-related protein 1 (LRP1) as an SAA recepto

29 The low density lipoprotein (LDL) receptor-related protein 1 (LRP1) belongs to a grow

30 astrocyte function, low-density lipoprotein (LDL) receptor-related protein 1 (LRP1), and the NF-kappa

31 mes bind tightly to low-density lipoprotein (LDL) receptor-related protein 1 (LRP1), but the molecula

32 ssociated protein, and by antibodies against LDL receptor-related protein-1 (LRP-1) and alpha(2)-macr

33 omposed of the receptor tyrosine kinase AXL, LDL receptor-related protein-1 (LRP-1), and RAN-binding

34 tective effect of tPA required its receptor, LDL receptor-related protein-1 (LRP-1).

35 Herein, we show that deletion of the LDL receptor-related protein-1 (LRP1) gene in Schwann ce

36 LDL receptor-related protein-1 (LRP1) is an endocytic an

37 death via an autocrine mechanism through the LDL receptor-related protein-1 (LRP1) receptor.

38 inactivation of the multifunctional receptor LDL receptor-related protein-1 (LRP1) to determine its r

39 ed nerve demonstrate increased expression of LDL receptor-related protein-1 (LRP1), an endocytic rece

40 The endocytic and cell signaling receptor, LDL receptor-related protein-1 (LRP1), is reported to su

41 iption factor in SCs, unless counteracted by LDL receptor-related protein-1 (LRP1), which serves as a

42 rant peptide Angiopep-2 (An2), which targets LDL receptor-related protein-1 (LRP1).

43 Rapid ERK1/2 activation is dependent on LDL receptor-related protein-1 (LRP1).

44 LDL Receptor-related Protein-1 (LRP1/CD91) binds diverse

45 LRP1 (LDL receptor-related protein-1) is a ubiquitous receptor

46 nternalized through low-density lipoprotein (LDL) receptor-related protein-1 (LRP-1) to become enzyma

47 Low-density lipoprotein (LDL) receptor-related protein-1 (LRP1) has been shown to

48 is a ligand for the Low Density Lipoprotein (LDL) Receptor-related Protein-1 (LRP1), a multifunctiona

49 The low density lipoprotein (LDL) receptor-related protein 1B (LRP1B) is a newly iden

50 The low density lipoprotein (LDL) receptor-related protein 1B (LRP1B) is a newly iden

51 bular protein extracts that we identified as LDL receptor-related protein 2 (LRP2), also known as meg

52 These included the LDL receptor-related protein 2, ATP synthase alpha chain

53 The low-density lipoprotein (LDL) receptor-related protein 2 (LRP2 or megalin) is rep

54 LDL receptor related proteins 5 and 6 (LRP5/6) and their

55 he closely related WNT signaling coreceptors LDL receptor-related protein 5 (LRP5) and LRP6 had redun

56 Here, we show that LDL receptor-related protein 5 (LRP5), but not its homol

57 through the frizzled class receptor 4 (FZD4)/LDL receptor-related protein 5-6 (LRP5-6)/tetraspanin 12

58 LDL receptor-related proteins 5 and 6 (LRP5/6) are corec

59 tes express several Wnt receptors, including LDL receptor-related proteins 5 and 6, and Frizzled 1 to

60 The low density lipoprotein (LDL) receptor-related protein 5 (LRP5) is a co-receptor

61 gle transmembrane protein in the LRP family (LDL-receptor-related protein 5/6 or Arrow) are essential

62 Mutation in the EGFP domain of LDL receptor-related protein 6 (LRP6(R611C)) is associat

63 y decreased expression of the Wnt coreceptor LDL receptor-related protein 6 (LRP6) in the mucosal tis

64 LDL receptor-related protein 6 (LRP6) is a Wnt corecepto

65 Loss-of-function mutations in Wnt coreceptor LDL receptor-related protein 6 (LRP6) underlie early-ons

66 f the frizzled (Fz) receptor, its coreceptor LDL receptor-related protein 6 (Lrp6), and the cytoplasm

67 We previously identified a mutation in LDL receptor-related protein 6 (LRP6), LRP6(R611C), that

68 (Fz) receptor and its candidate coreceptor, LDL receptor-related protein 6 (LRP6), presumably throug

69 that bind to the Frizzled (FZD) receptor and LDL receptor-related protein 6 (LRP6).

70 These effects required the WNT receptor LDL receptor-related protein 6 (LRP6).

71 h its ability to bind to the Wnt co-receptor LDL receptor-related protein 6 (LRP6).

72 ivation was determined by phosphorylation of LDL receptor-related protein 6, a coreceptor of Wnt liga

73 smembrane receptor, low-density lipoprotein (LDL)-receptor-related protein 6 (LRP6), whose phosphoryl

74 LDL-receptor-related protein 6 (LRP6), alongside Frizzle

75 The low-density lipoprotein (LDL) receptor-related protein-6 (LRP6), a novel member o

76 is a molecular chaperone/escort protein for LDL receptor-related protein, a member of the LDL recept

77 ding site for alpha 2-macroglobulin receptor/LDL receptor-related protein (alpha 2 MR/LRP) was lost,

78 ha(2)M), suggesting the participation of the LDL receptor-related protein/alpha(2)M receptor.

79 he 39-kDa inhibitor of ligand binding to the LDL receptor-related protein and the very low density li

80 of lipoprotein binding to the LDL receptor, LDL receptor-related protein, and VLDL receptor.

81 or-associated protein, and a polyclonal anti-LDL receptor-related protein antibody.

82 th active tissue-type plasminogen activator, LDL receptor-related protein appears to control permeabi

83 Low-density lipoprotein (LDL) receptor-related protein-associated protein 1 (LRPA

84 t receptor-associated protein interacts with LDL receptor-related protein at multiple sites and assis

85 hese data identify a major receptor pathway (LDL receptor-related protein) by which the ligand-bindin

86 e receptor is a heparan sulfate proteoglycan-LDL receptor-related protein complex.

87 ole for RAP as a molecular chaperone for the LDL receptor-related protein during receptor folding and

88 a new member of the low-density lipoprotein (LDL)-receptor-related protein family, LRP6, is critical

89 eptor-associated protein (RAP), which blocks LDL receptor-related protein function, decreased plasma

90 Recently, an LDL-receptor-related protein has been shown to function

91 ipoprotein E (ApoE) receptors, also known as LDL receptor-related proteins, have distinguished themse

92 ing protein that is involved in signaling by LDL receptor-related proteins in the nervous system, did

93 of LDL receptor knockout (LDLr0) and hepatic LDL receptor-related protein knockout/LDLr0 mice, but fo

94 Moreover, antibodies to the LDL receptor-related protein (LRP) and an LRP antagonist

95 the activity is blocked by antibodies to the LDL receptor-related protein (LRP) and by the LRP antago

96 Remarkably, the LDL receptor-related protein (LRP) and its ligands, apoE

97 e low-density lipoprotein (LDL) receptor and LDL receptor-related protein (LRP) in seven human glioma

98 xamined the role of uPAR and its co-receptor LDL receptor-related protein (LRP) in the regulation of

99 Furthermore, the cytoplasmic domain of the LDL receptor-related protein (LRP) was found to be a sub

100 protein (LDL) receptor family, including the LDL receptor-related protein (LRP), GP330/LRP-2, and ver

101 observed independent of the presence of the LDL receptor-related protein (LRP), LDLR, or both.

102 low density lipoprotein receptor (LDLR), the LDL receptor-related protein (LRP), the very low density

103 receptor, and lactoferrin, which blocks the LDL receptor-related protein (LRP), were found to decrea

104 ) to determine the potential contribution of LDL receptor-related protein (LRP).

105 or family that shares high homology with the LDL receptor-related protein (LRP).

106 sis signal(s) within the cytoplasmic tail of LDL receptor-related protein (LRP).

107 The macrophage LDL receptor and LDL receptor-related protein (LRP, CD91) mediate the pha

108 of the TGF-beta-dependent signaling pathway: LDL receptor-related protein (LRP-1) and decorin.

109 poE is a ligand for low-density lipoprotein (LDL) receptor-related protein (LRP) but not the LDL rece

110 The multifunctional low density lipoprotein (LDL) receptor-related protein (LRP) forms a complex with

111 The multifunctional low density lipoprotein (LDL) receptor-related protein (LRP) has been postulated

112 The low-density lipoprotein (LDL) receptor-related protein (LRP) is a multifunctional

113 The low density lipoprotein (LDL) receptor-related protein (LRP) is a multifunctional

114 The low-density lipoprotein (LDL) receptor-related protein (LRP) is a multiligand end

115 The low-density lipoprotein (LDL) receptor-related protein (LRP) is a multiligand end

116 are ligands for the low density lipoprotein (LDL) receptor-related protein (LRP), an abundant neurona

117 Arrow is a low-density lipoprotein (LDL)-receptor-related protein (LRP), strikingly homologo

118 recognition ligand by binding and activating LDL-receptor-related protein (LRP) on the engulfing cell

119 LDL receptor-related protein (LRP1) is an endocytic and

120 LDL receptor-related protein (LRP1) is expressed by Schw

121 l surface stimulates association of CRT with LDL receptor-related protein (LRP1) to signal focal adhe

122 of LTP across the Blood Brain Barrier by two LDL receptor-related proteins: LRP1 and Megalin.

123 rosophila and zebrafish hearts revealed that LDL receptor-related protein LRP2 is required for cardio

124 One such organizer, the LDL receptor-related protein LRP4, is a cell surface rec

125 d (Fz) family member alone or complexed with LDL receptor-related proteins (LRP5/6).

126 Particle uptake by the LDL receptor, by the LDL receptor related protein, or by scavenger receptors

127 omes, this uptake did not occur through LDL, LDL receptor-related protein, or scavenger receptors.

128 Mutations disrupting LDL-receptor related proteins produce loss-of-function W

129 and heparinase, the low-density lipoprotein (LDL) receptor-related protein receptor-associated protei

130 ular WNT activation by binding to the Kremen/LDL receptor-related protein receptors, was not seen wit

131 The biosynthesis and export of LDL receptor-related proteins rely on specialized chaper

132 onding region of another LDL-A module, human LDL receptor-related protein repeat 22 (LDL-A22), to med

133 e human LDL receptor homology regions of the LDL receptor-related protein (sLRP2, sLRP3, and sLRP4) h

134 n the cell surface and can interact with the LDL receptor-related protein, which has been implicated

135 hylogenetically conserved subfamily of giant LDL receptor-related proteins, which function in endocyt

136 oper folding and disulfide bond formation of LDL receptor-related protein within the endoplasmic reti