ライフサイエンスコーパス: LIF receptor

1 ough a c12-gp130 complex; it did not use the LIF receptor.

2 SM receptor; human OSM instead activates the LIF receptor.

3 s PBEF via its OSM receptor beta and not its LIF receptor.

4 tenuated by immuneutralization of either the LIF receptor (35%, P<0.05) or the gp130 affinity convert

5 We conclude that gp130/LIF receptor and ET(A) receptor activation are essential

6 estigated the interaction between CT-1/gp130/LIF receptor and ET-1/endothelin type A (ET(A)) receptor

7 ctor (LIF) consists of two polypeptides, the LIF receptor and gp130.

8 Both murine LIF (cannot bind to human LIF receptor) and human LIF caused expansion of human CD

9 tripartite complex comprised of CNTFRalpha, LIF receptor, and gp130.

10 Leukemia inhibitory factor (LIF) and LIF receptors are expressed in adenohypophyseal cells an

11 During this time, LIF receptors are expressed predominantly in the luminal

12 endogenous and exogenous CT-1 requires gp130/LIF receptor as well as ET(A) receptor activation.

13 TF, and CT-1 act through the known receptors LIF receptor beta (LIFRbeta) and gp130 and well defined

14 3T3 cells (which endogenously express gp130, LIF receptor beta [LIFRbeta], and the protein product, c

15 n M and ciliary neurotrophic factor, and the LIF receptor beta and glycoprotein gp130 in normal human

16 The LIF receptor beta is expressed during the proliferative

17 nd FoxD3 as well as in the expression of the LIF receptor complex LIFR/IL6ST (gp130).

18 RG cells express leukemia-inhibitory factor (LIF) receptors during neurogenesis, and consistent with

19 ed to upregulate leukemia inhibitory factor (LIF) receptor, epidermal growth factor-like transforming

20 We recently reported LIF and LIF receptor expression in human fetal pituitary cortico

21 uterus increased HLA-G, EGF-Receptor-2, and LIF-Receptor expression on EVT, presumably representing

22 f mice carrying a targeted disruption of the LIF receptor gene, a common component of the receptor co

23 sociated signal-transducing component of the LIF receptor, gp130, is also expressed in both the lumin

24 t sortilin is essential for co-activation of LIF receptor/gp130 signaling in BECs, but not for IL-6 s

25 Leukemia inhibitory factor (LIF) and LIF receptors have been implicated previously in astrocy

26 Blockade of gp130 or LIF receptor inhibited basal growth as well as CT-1- or

27 LIF/LIF receptor interactions induced ETGF and IL-10 product

28 Liver-specific LIF receptor knockout attenuates LIF-induced cachexia, s

29 keletal muscles, we examined whether the LIF-LIF receptor (LIF-R) axis affects the biology of rhabdom

30 -6 promoter after fibroblast activation, and LIF receptor (LIFR) and STAT4 formed a molecular complex

31 (LIF, OSM, CNTF, and CT-1) also utilize the LIF receptor (LIFR) as a component of their receptor com

32 tes giant cell differentiation in vitro, and LIF receptor (LIFR) deficiency results in loss of giant

33 he hypothesis that the reduced expression of LIF receptor (LIFR) observed in hepatoma cells is mediat

34 LIF/OSM receptor (a heterodimer of gp130 and LIF receptor (LIFR)) and the OSM-specific receptor (a he

35 d murine LIF (mLIF) act in mouse cells via a LIF receptor (LIFR)-glycoprotein 130 (gp130) heterodimer

36 receptor complex composed of a low affinity LIF receptor (LIFRbeta) and gp130.

37 weeks with a monoclonal antibody against the LIF receptor motif, gp130 (0.833 mg ml-1) (P < 0.05, Man

38 cells, we hypothesized that LIF binds to the LIF receptor on AC6.21 stromal cells, leading to up-regu

39 n130 (gp130) and leukemia inhibitory factor (LIF) receptor, on cardiac fibroblast growth in cultured

40 ation of SHP-2 with the gp130 subunit of the LIF receptor signaling complex.

41 Treatment with either soluble LIF receptor (sLIFR), a LIF antagonist, or the mTOR inhi

42 y despite the presence of constant levels of LIF receptor throughout the preimplantation period.

43 However, anti-E2 antibody localized the LIF receptor to areas of E2 expression on the infected c

44 CT-1 and gp130/LIF receptor were widely present in the cytoplasm of the