ライフサイエンスコーパス: Leishmania major

1 responses against the intracellular pathogen Leishmania major.

2 it were identified in Trypanosoma brucei and Leishmania major.

3 ry to treatment than leishmaniasis caused by Leishmania major.

4 uced by the obligate intracellular parasite, Leishmania major.

5 in Trypanosoma cruzi, Trypanosoma brucei and Leishmania major.

6 as been recently identified in the genome of Leishmania major.

7 acellular pathogens, including the parasite, Leishmania major.

8 es Trypanosoma brucei, Trypanosoma cruzi and Leishmania major.

9 on is decreased after an initial response to Leishmania major.

10 s: Trypanosoma brucei, Trypanosoma cruzi and Leishmania major.

11 ty against cutaneous leishmaniasis caused by Leishmania major.

12 l outcome in rhesus macaques challenged with Leishmania major.

13 ce to infections with the protozoan parasite Leishmania major.

14 ine transporter from the protozoan pathogen, Leishmania major.

15 rides and proteins in the protozoan parasite Leishmania major.

16 clone the gene for a homologue, LmACR2, from Leishmania major.

17 ility to infection by the protozoal parasite Leishmania major.

18 istant C3H mice 2 weeks after infection with Leishmania major.

19 mice after infection with different doses of Leishmania major.

20 panosoma brucei(TB), T. vivax, T. cruzi, and Leishmania major.

21 LAM(-/-) C57Bl/6 mice to remove the parasite Leishmania major.

22 on with the intracellular protozoan parasite Leishmania major.

23 t plays key roles in the infectious cycle of Leishmania major.

24 ses healing in CD40L(-/-) mice infected with Leishmania major.

25 hly resistant to the Th2-inducing protozoan, Leishmania major.

26 eatment of cutaneous leishmaniasis caused by Leishmania major.

27 to infection with the intracellular parasite Leishmania major.

28 teins of Phlebotomus papatasi, the vector of Leishmania major.

29 ed BALB IL-6-deficient (IL-6(-/-)) mice with Leishmania major.

30 stic of T(H)2 responses and are resistant to Leishmania major.

31 istance to cutaneous leishmaniasis caused by Leishmania major.

32 unization with protein Ags or infection with Leishmania major.

33 erimental parasitic cutaneous infection with Leishmania major.

34 e form of leishmaniasis after infection with Leishmania major.

35 xpressed, and characterized Ncb5or gene from Leishmania major.

36 t of leishmaniasis is the protozoan parasite Leishmania major.

37 against the intracellular protozoan parasite Leishmania major.

38 were evaluated for inhibition of recombinant Leishmania major 24-SMT and the effect of compounds on s

39 For the human pathogen Leishmania major, a key metabolic function is the synthe

40 was necessary for effective immunity against Leishmania major, a parasite whose clearance requires TL

41 nhibitors, whereas control of infection with Leishmania major, a Th1-dependent response, was enhanced

42 able produce NO or kill Trypanosoma cruzi or Leishmania major after priming with IFN-gamma.

43 We generated null mutants of the Leishmania major alkyldihydroxyacetonephosphate synthase

44 cal grade of leishmanial antigen, autoclaved Leishmania major (ALM), or a recombinant leishmanial pro

45 That similar regions of Leishmania major also contain base J highlights the func

46 Cutaneous leishmaniasis, caused mainly by Leishmania major, an obligate intracellular parasite, is

47 To address this issue, we infected mice with Leishmania major and 2 wk later with lymphocytic choriom

48 Leishmania major and all other parasitic protozoa are un

49 exes 1-8 are active against promastigotes of Leishmania major and epimastigotes of Trypanosoma cruzi.

50 ected NF-kappa B2(-/-) and control mice with Leishmania major and followed disease progression.

51 -infection of C3HeB/FeJ (C3H) mice with both Leishmania major and Leishmania amazonensis leads to a h

52 -)also demonstrated cross-protection against Leishmania major and Leishmania braziliensis infection.

53 taneous and visceral leishmaniasis caused by Leishmania major and Leishmania donovani, respectively.

54 rious fragments of proteophosphoglycans from Leishmania major and Leishmania mexicana proteophosphogl

55 against an intradermal needle challenge with Leishmania major and sand fly saliva when vaccinated int

56 regulation of inflammatory responses toward Leishmania major and Shigella flexneri infection.

57 cgammaR(-/-) mice can control infection with Leishmania major and totally resolve cutaneous lesions.

58 nstrated that C57BL/6 mice coinoculated with Leishmania major and trimannose-coated beads produced si

59 netic deletions, we inhibited J synthesis in Leishmania major and Trypanosoma brucei using DMOG.

60 ormat for a rapid and easy discrimination of Leishmania major and Trypanosoma cruzi.

61 lymphocytic leukemia), parasitic infection (Leishmania major), and infectious disease (Listeria mono

62 -like sequences in Trypanosoma brucei, 27 in Leishmania major, and 24 in Trypanosoma cruzi.

63 Leishmania major aquaglyceroporin (LmjAQP1) adventitious

64 The Leishmania major aquaglyceroporin, LmAQP1, is responsibl

65 The Leishmania major aquaglyceroporin, LmAQP1, is responsibl

66 early IFN-gamma production and resistance to Leishmania major are impaired in the absence of WSX-1 si

67 anosoma brucei brucei, Trypanosoma cruzi and Leishmania major - are now complete, providing both a mi

68 the sandfly Phlebotomus papatasi, is used by Leishmania major as a receptor for mediating specific bi

69 parasite load upon secondary infection with Leishmania major as well as a reduction in DTH responses

70 e TOR kinases in the trypanosomatid parasite Leishmania major, as defined by homology to the phosphoi

71 TG mice mount impaired Th1 responses against Leishmania major, as manifested by increased parasitemia

72 coli monofunctional TS and in T. gondii and Leishmania major bifunctional TS-DHFR.

73 and fly infections by the protozoan parasite Leishmania major, binding of replicating promastigotes i

74 C3H and C57BL/6 mice are resistant to Leishmania major but develop chronic lesions with persis

75 nhanced resistance to the protozoan parasite Leishmania major but impaired immunity to the intestinal

76 the individual contributions of each ATG4 to Leishmania major by generating individual gene deletion

77 Role of protein kinase R in the killing of Leishmania major by macrophages in response to neutrophi

78 Leishmania major causes cutaneous leishmaniasis.

79 gene, named Lmsp1, was cloned by screening a Leishmania major cDNA expression library using a rabbit

80 The potential of Leishmania major culture-derived soluble exogenous antig

81 rotozoal species: T. cruzi (Chagas disease), Leishmania major (cutaneous leishmaniasis), and Plasmodi

82 Previously, we showed that Leishmania major deletion mutants lacking the Golgi GDP-

83 hat results in ulcer-free protection against Leishmania major delivered by vector bites.

84 uclease/phosphatase (EEP) motif protein from Leishmania major, designated RNA editing exonuclease 1 (

85 C3HeB/FeJ mice challenged with Leishmania major develop a polarized Th1 response and su

86 BALB/c mice infected with Leishmania major developed a type 2 immune response whic

87 continuum modeling suggest that compared to Leishmania major DHFR-TS, P. falciparum DHFR-TS has a lo

88 was similar in the 2 strains, infectivity to Leishmania major differed, as did macrophage uptake of a

89 superior to aquaphilic vehicle for Old World Leishmania major disease.

90 with protein or infection with the protozoon Leishmania major, draining lymph nodes (LNs) of IFN-regu

91 ng infection of susceptible BALB/c mice with Leishmania major, early production of interleukin-4 (IL-

92 In BALB/c mice infected with Leishmania major, early secretion of IL-4 leads to a Th2

93 In contrast, Leishmania major elicits a robust Th1 response that prom

94 Leishmania major encodes 2 orthologs of the cytokine mac

95 ion 3 days before and after a challenge with Leishmania major enhanced host resistance and reduced th

96 For example, the Leishmania major enzyme LmACR2 is both a phosphatase and

97 gondii growth inhibition and FPPS (human and Leishmania major) enzyme inhibition and by the fact that

98 gainst recombinant Plasmodium falciparum and Leishmania major enzymes and the human enzyme to give a

99 stimulation by microbial pathogens, such as Leishmania major, Escherichia coli, and Mycobacterium bo

100 worthily, UCNII killed the infective form of Leishmania major even inside the infected macrophages.

101 that while normal BALB/c mice infected with Leishmania major exhibited a nonhealing phenotype, those

102 n, purification, and characterization of the Leishmania major exopolyphosphatase (LmPPX).

103 cutaneous compartment during infection with Leishmania major express P- and E-selectin ligands.

104 Leishmania major expresses two purine nucleobase transpo

105 e that the causative agent of leishmaniasis, Leishmania major, expresses an FMN-containing nitroreduc

106 ng infection with the intracellular parasite Leishmania major, expression of inducible NO synthase do

107 nds); R = 0.82, p < 0.0001, for an expressed Leishmania major FPPS (N = 45 compounds).

108 ptional analysis of chromosome 1 (chr1) from Leishmania major Friedlin (LmjF) which encodes the first

109 The complete nucleotide sequence of Leishmania major Friedlin chromosome 1 revealed 79 prote

110 e chromosomal sequence for chromosome 1 from LEISHMANIA: major Friedlin predicts that this chromosome

111 somes of the 32.8-megabase haploid genome of Leishmania major (Friedlin strain) and predict 911 RNA g

112 We examined the Leishmania major (Friedlin) and Trypanosoma cruzi (CL Br

113 A comparison of three crystal structures of Leishmania major fructose-1,6-bisphosphatase (LmFBPase)

114 distribution of thymine modifications in the Leishmania major genome by enzymatically converting thes

115 In our study, Leishmania major grew normally in RAW cells, RAW-express

116 accination through leishmanization with live Leishmania major has been used successfully but is no lo

117 om Trypanosoma brucei, Trypanosoma cruzi and Leishmania major identified protein motifs associated wi

118 n of macrophages with the protozoan parasite Leishmania major impairs PKCalpha, betaI, betaII, and ep

119 Infection with Leishmania major in BALB/c mice is accompanied by the de

120 s necessary for the long term maintenance of Leishmania major in genetically resistant C57BL/6 mice a

121 ccumulate at sites of chronic infection with Leishmania major in mice.

122 s disease following sand fly transmission of Leishmania major in susceptible BALB/c mice.

123 ave recently demonstrated protection against Leishmania major in the murine and nonhuman primate mode

124 Here we show that the persistence of Leishmania major in the skin after healing in resistant

125 e control of intracellular parasites such as Leishmania major In this study, we tested whether Arg1 i

126 micin, for cutaneous leishmaniasis caused by Leishmania major in Tunisia.

127 ia-naive donors and cultured with or without Leishmania major in various combinations.

128 e been shown to be crucial for resistance to Leishmania major in vivo For example, mice in the resist

129 ted protective T-helper 1 (Th1) responses to Leishmania major in vivo, but were unable to support Th2

130 es (Trypanosoma cruzi, Toxoplasma gondii and Leishmania major), in which the Gzms generate superoxide

131 high activity against an expressed FPPS from Leishmania major, in Dictyostelium discoideum growth inh

132 y important roles in the infectious cycle of Leishmania major, including the abundant lipophosphoglyc

133 We found that infection with Leishmania major increases the expression of vascular en

134 Infection with Leishmania major induces a protective immune response an

135 on with the intracellular protozoan parasite Leishmania major induces a state of concomitant immunity

136 Leishmania major-infected human dendritic cells (DCs) ex

137 In this study, we report that in Leishmania major-infected macrophages, the expression of

138 lls from the draining lymph nodes of treated Leishmania major-infected mice compared with cells from

139 pulation of central memory CD4(+) T cells in Leishmania major-infected mice that were capable of medi

140 Itgb2(-/-) mice were better able to resolve Leishmania major infection and generated a superior T(H)

141 CD40 plays dual immunoregulatory roles in Leishmania major infection and tumor regression.

142 In this article, we compared the outcome of Leishmania major infection in both CD40- and CD40L-defic

143 Experimental Leishmania major infection in mice has been of immense i

144 e show that the degree of protection against Leishmania major infection in mice is predicted by the f

145 During Leishmania major infection in mice, gamma interferon (IF

146 f Semaphorin 3E (Sema3E) in host immunity to Leishmania major infection in mice.

147 aniasis, we analyzed the course of cutaneous Leishmania major infection in MIF gene-deficient mice (M

148 with the spontaneous reactivation of chronic Leishmania major infection in old mice, likely because o

149 cells suppressed the disease development of Leishmania major infection in SCID mice reconstituted wi

150 ruct induce equally solid protection against Leishmania major infection in susceptible BALB/c mice.

151 ype, TACI-KO Mvarphis were unable to control Leishmania major infection in vitro, and intradermal ino

152 is, we examined lesion development following Leishmania major infection of genetically susceptible BA

153 leukocytes were recruited into lesions after Leishmania major infection of mice.

154 benefit (detente cordiale) such as occurs in Leishmania major infection of resistant mouse strains, t

155 Here, we show that cutaneous Leishmania major infection stimulated expression of the

156 S IV-deficient mice were more susceptible to Leishmania major infection than were wild-type littermat

157 gene for CD40L (CD40L(-/-) mice) can control Leishmania major infection when they are infected with r

158 After Leishmania major infection, disease progression was dete

159 Here, we used a mouse model of Leishmania major infection, in which parasite persistenc

160 In Leishmania major infection, manipulating Pias1 expressio

161 or IEX-1 in control of the susceptibility to Leishmania major infection, the inflammatory response du

162 In a mouse model of Leishmania major infection, vaccination with heat-killed

163 D4(+) T cell responses in the mouse model of Leishmania major infection.

164 is indispensable for host resistance against Leishmania major infection.

165 tion and analysis of an agent-based model of Leishmania major infection.

166 K1-deficient mice were highly susceptible to Leishmania major infection.

167 Genetic background influences the outcome of Leishmania major infection.

168 , regulates Ca2+ influx, and defends against Leishmania major infection.

169 edominant cell type expressing VEGF-A during Leishmania major infection.

170 or of the cutaneous inflammatory response to Leishmania major infection.

171 ecessary for the homing of T(reg) at site of Leishmania major infection.

172 e Th1 cell responses and are able to control Leishmania major infection.

173 ce, something that conferred protection from Leishmania major infection.

174 ignaling were evaluated in a murine model of Leishmania major infection.

175 tokine Flt3L would protect against cutaneous Leishmania major infection.

176 from house dust mite (HDM)-induced asthma or Leishmania major infection.

177 enetic background, are highly susceptible to Leishmania major infection.

178 at LJM11 confers protective immunity against Leishmania major infection.

179 Since nonhealing Leishmania major infections in susceptible BALB/c mice h

180 site burden compared to wild-type mice after Leishmania major intradermal ear infection.

181 Leishmania major is a parasite that resides and replicat

182 Leishmania major is an obligately intracellular protozoa

183 ously shown that persistence of the parasite Leishmania major is controlled by endogenous CD4(+) CD25

184 Cure of infections with Leishmania major is critically dependent on the ability

185 Control of the protozoan parasite Leishmania major is dependent on establishing a robust T

186 Infection with Leishmania major is enhanced when the sand fly Lutzomyia

187 Protection from the parasite Leishmania major is mediated by CD4 T cells.

188 Protective immunity against Leishmania major is provided by s.c. immunization with a

189 We show that TLR2 triggering by Leishmania major is required for their secretion of neut

190 nfection in C3H mice, whereas infection with Leishmania major is self-healing.

191 In particular, we have generated a Leishmania major iscl(-) mutant which is deficient in SL

192 In this paper, we show that a strain of Leishmania major (L. major Seidman [LmSd]) that produces

193 is associated with resistance to developing Leishmania major (L. major) infection.

194 Invading neutrophils efficiently captured Leishmania major (L.m.) parasites early after sand fly t

195 The Leishmania major LACK antigen contains an immunodominant

196 The Leishmania major LACK antigen is a key target of the imm

197 CD4 T cells specific for the immunodominant Leishmania major LACK antigen using MHC/peptide tetramer

198 Leishmania major lacking phosphoglycans (lpg2-) were una

199 o study truly lpg(-) parasites, we generated Leishmania major lacking the gene LPG1 [encoding a putat

200 and to phylogenetically distinct protozoan (Leishmania major, Leishmania donovani, Toxoplasma gondii

201 istance to intracellular organisms including Leishmania major, Leishmania mexicana, and Listeria mono

202 ut could not inhibit the growth of cutaneous Leishmania major lesions.

203 pathogenesis of the human protozoan parasite Leishmania major, little is known about the enzymes and

204 CD8+ T cells are generated in response to Leishmania major (Lm) or Toxoplasma gondii parasitic inf

205 d characterization of aquaglyceroporins from Leishmania major (LmAQP1) and Leishmania tarentolae (LtA

206 Here we used an Leishmania major lpg1- mutant, which lacks LPG alone and

207 sted of mice challenged in the ear with live Leishmania major metacyclic promastigotes.

208 s of 62 bisphosphonates as inhibitors of the Leishmania major mevalonate/isoprene biosynthesis pathwa

209 Using the Leishmania major mouse model of dermal infection, we obs

210 In contrast, L. donovani and Leishmania major mutants deficient solely in LPG express

211 Since Leishmania major mutants that lack lipophosphoglycan and

212 hiopica (n = 4), Leishmania tropica (n = 2), Leishmania major (n = 1), and unspeciated (n = 3).

213 e analyses of 12 derivatives in complex with Leishmania major NMT revealed key factors important for

214 Crystal structures bound to Leishmania major NMT were obtained, and the active diast

215 oles of the four purine permeases NT1-NT4 in Leishmania major, null mutants in each transporter gene

216 synthase-dihydrofolate reductase enzyme from Leishmania major occurs via electrostatic interactions b

217 ew virulence factors have been described for Leishmania major, one of the causative agents of cutaneo

218 We find two populations of persistent Leishmania major: one rapidly replicating, similar to pa

219 n this study we expressed active recombinant Leishmania major OPB and provide the first structure of

220 uction of genes encoding Ddi1 orthologs from Leishmania major or humans.

221 acute lymphocytic choriomeningitis virus and Leishmania major parasite infections, which were rescued

222 PCR-based method to determine the number of Leishmania major parasites inoculated into the ears of l

223 ibutes to the innate immune response against Leishmania major parasites is unknown.

224 Leishmania major parasites lacking the GDP-mannose trans

225 ellular infection, we previously showed that Leishmania major parasites prime human DC for efficient

226 We observed that when challenged with Leishmania major parasites, mice immunized intradermally

227 The glf homolog from the protozoan Leishmania major partially complements C. elegans glf-1.

228 specific P-pocket found in the structures of Leishmania major PDEB1 and Trypanosoma cruzi PDEC.

229 Leishmania major phosphodiesterases (LmjPDEs) have been

230 nses against neo and recall antigens using a Leishmania major polyprotein (MML) vaccine given with po

231 Leishmania major possesses single DHCH1 and FTL genes en

232 e wild-type BALB/c (H-2d) mice infected with Leishmania major predominantly recognize a single epitop

233 In Leishmania major, PRMT7 is a cytoplasmic protein implici

234 The parasitic protozoa Leishmania major produces a peroxidase (L. major peroxid

235 (DCs) of C57BL/6 mice with L. amazonensis or Leishmania major promastigotes and assessed the activati

236 In this study, we show that Leishmania major promastigotes express a single glycerol

237 have demonstrated that products secreted by Leishmania major promastigotes inhibit the motility of d

238 volving s.c. inoculation of large numbers of Leishmania major promastigotes, have not supported an es

239 s Trypanosoma brucei, Trypanosoma cruzi, and Leishmania major provides an opportunity to determine th

240 ice, we report that cutaneous infection with Leishmania major provides heterologous protection agains

241 shares 50% amino acid sequence identity with Leishmania major PTR1 (LmPTR1) and comparisons show that

242 A series of crystallographic analyses of Leishmania major PTR1 are reported.

243 versed by expression of enzymatically active Leishmania major PTR1 in RNAi lines ((oe)RNAi) or by add

244 nds were assessed for Trypanosoma brucei and Leishmania major PTR1 inhibition and in vitro activity a

245 Here we characterize Leishmania major quinonoid-dihydropteridine reductase (L

246 Control of infection caused by Leishmania major requires the development of IFN-gamma+C

247 Control of the intracellular protozoan, Leishmania major, requires major histocompatibility comp

248 Infection of mice with Leishmania major results in disease progression or resol

249 these sequences with the published genome of Leishmania major reveals marked conservation of synteny

250 es of DHFR-TS from Plasmodium falciparum and Leishmania major reveals that the linker domain primaril

251 d by the genomes of T. brucei, T. cruzi, and Leishmania major reveals the least overall metabolic cap

252 The Leishmania major RNA ligase-containing complex protein 2

253 Here we show that Leishmania major SAS-6 crystallizes as a 9-fold symmetri

254 In Leishmania major strain Friedlin, this is controlled by

255 Using a Leishmania major strain that produces nonhealing dermal

256 Genetic exchange between Leishmania major strains during their development in the

257 proteins, thiol-specific antioxidant (TSA), Leishmania major stress-inducible protein 1 (LmSTI1), an

258 Th2 responses, remain highly susceptible to Leishmania major substain LV39 due exclusively to residu

259 ated to TbMSP-B, a trypanosomal homologue of Leishmania major surface protease (MSP) described in the

260 e immunity after adoptive transfer in naive, Leishmania major susceptible BALB/c mice.

261 endent effects were evident in DCs from both Leishmania major-susceptible (BALB/c) and -resistant (C3

262 by prior infection or live vaccination with Leishmania major, termed leishmanization.

263 locus, were more resistant to infection with Leishmania major than were normal BALB/c mice.

264 s for representatives of the Kinetoplastida (Leishmania major), the Parabasalia (Trichomonas vaginali

265 ut mutants and their complemented strains in Leishmania major, the causative agent for cutaneous leis

266 Following infection with Leishmania major, the chemokines XCL1, CXCL10, and CCL2

267 In Leishmania major, the first step in methylglyoxal detoxi

268 aryotes, but in the trypanosomatid protozoan Leishmania major their functions differ significantly.

269 f Trypanosoma brucei, Trypanosoma cruzi, and Leishmania major, three related pathogens with different

270 am-negative bacteria as well as the parasite Leishmania major through a mechanism that depends on the

271 d a SL null mutant in the protozoan parasite Leishmania major through targeted deletion of the key de

272 we investigated the role of PME synthesis in Leishmania major through the characterization of an etha

273 is most often caused by the transmission of Leishmania major to humans by female phlebotomine sand f

274 The inoculation of live, nonattenuated Leishmania major to produce a lesion in a selected site

275 nses of SAP-deficient mice to infection with Leishmania major together with in vitro studies showed t

276 Analyses of the T. cruzi, T. brucei, and Leishmania major (Tritryp) genomes imply differences fro

277 bacterial and parasitic pathogens including Leishmania major, Trypanosoma cruzi, and Neisseria gonor

278 deletion of the analogous N-terminal tail in Leishmania major TS-DHFR causes a 3-fold enhancement of

279 is a 100 microm non-active site inhibitor of Leishmania major TS-DHFR identified by molecular docking

280 Furthermore, whereas with Leishmania major TS-DHFR there are multiple lines of evi

281 c expression of TS in an unrelated parasite, Leishmania major, turned those parasites into activators

282 However, crystal structures of Leishmania major TyrRS show that, instead, the two halve

283 estigate the role of de novo PC synthesis in Leishmania major, we focused on the cholinephosphate cyt

284 e development of protective immunity against Leishmania major, we have analyzed the course of cutaneo

285 CK1alpha and L-CK1 produced by the protozoan Leishmania major were also capable of increasing IFNAR1

286 cines against cutaneous leishmaniasis due to Leishmania major were evaluated using a challenge model

287 nt MP90 proteins from Trypanosoma brucei and Leishmania major were expressed in insect cells and cyto

288 f Trypanosoma brucei, Trypanosoma cruzi, and Leishmania major were identified.

289 nt lipophosphoglycan biosynthetic genes from Leishmania major were knocked out, there was a clear los

290 an keratinocytes with Leishmania infantum or Leishmania major, which cause visceral or cutaneous leis

291 hmania amazonensis, Leishmania donovani, and Leishmania major, which encoded 60-kDa proteins that dis

292 ion of the obligately intracellular parasite Leishmania major, which is transmitted in nature followi

293 cture of a class I FH, the cytosolic FH from Leishmania major, which reveals a previously undiscovere

294 ote susceptibility to the protozoan parasite Leishmania major, while conferring immunity to the intes

295 with an IC(50) of 15.4 microM and inhibited Leishmania major with an IC(50) of 12.5 microM.

296 wed a significant cytotoxic activity against Leishmania major with IC50 values of 26.2, 20.2, 12.1, a

297 eath of the intracellular protozoan parasite Leishmania major with no host cell toxicity.

298 dentified by targeting the LACK antigen from Leishmania major within an antibody to CD205 (DEC-205),

299 To determine whether an ongoing response to Leishmania major would affect the response to a non-cros

300 unity to the obligate intracellular parasite Leishmania major, yet inoculation with live, wild-type L