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1 MAC (mitral annular calcium score >0) was present in 35
2 MAC activity ((18)F-fluoride uptake) was closely associa
3 MAC adopts a 'split-washer' configuration, in contrast t
4 MAC is associated with better OS, EFS, and DFS.
5 MAC is characterized by increased local calcification ac
6 MAC pulmonary disease (MAC-PD) can be chronic, debilitat
7 MAC score was found to be an independent predictor of CS
8 MAC strains show a wide genetic variability, and there i
9 MAC was present in 1,149 participants (20.4%).
10 MAC were not detected in either system.
11 MAC, AoV, and left ventricular outflow tract calcium (Ca
12 MAC-activated cells have been found to express proinflam
13 MAC-PD is difficult to treat, with frequent drug-related
14 MACs and OCs undergo highly similar 5hmC and 5mC changes
15 The Chembio DPP Zika ICA and InBios ZIKV 2.0 MAC-ELISA showed >95% specificity in 22 ZIKV/DENV-serone
17 Bios ZIKV MAC-ELISA with the InBios ZIKV 2.0 MAC-ELISA will lead to fewer samples requiring PRNT, min
18 enzyme-linked immunosorbent assay (ZIKV 2.0 MAC-ELISA; InBios international, Inc., Seattle, WA), whi
19 remaining patients were categorized into (1) MAC and (2) elective intubation for the procedure (elect
21 e of numerous PSCs to upregulate galectin-3 (MAC-2), a marker of glial axonal debris phagocytosis, on
22 whole-genome sequencing were performed on 40 MAC isolates isolated from 15 patients at the Department
23 erence strains and 145 clinical isolates (58 MAC and 87 M. abscessus isolates), including 54 clarithr
25 econd, we find that optimal performance of a MAC with bounded-size inputs may require unbounded amoun
31 lic carbene ligands, monoamido-aminocarbene (MAC*) and diamidocarbene (DAC*), along with carbazolyl (
34 illness from exposure to L. pneumophila and MAC via showering were generally low (i.e., less than a
36 (carbene)M((I))(N-carbazolyl) (M(CAAC)) and (MAC)M((I))(N-carbazolyl) (M(MAC)) complexes show coplana
37 an MAC-PP, the highest AFS grade and no anti-MAC treatment were correlated with radiographic progress
39 logical persistence of MAC-LD was defined as MAC-PP exceeding 1 year, in contrast with the negative-c
40 y capture enzyme-linked immunosorbent assay (MAC-ELISA) followed by supplemental testing of specimens
41 y capture enzyme-linked immunosorbent assay (MAC-ELISA) for screening, followed by a confirmatory pla
45 nd inner membrane and thus kill a bacterium, MACs need to be assembled locally by the C5 convertase e
51 lysis by expression of inhibitors that block MAC assembly or by rapid removal of MAC through endocyto
54 lkyl), monoamido, or diamido carbenes (CAAC, MAC, or DAC, respectively) as chromophore ligands reveal
56 ting of severe mitral annular calcification (MAC) is challenging due to the high risk for fatal atrio
59 aluate the impact of mitral annular calcium (MAC) score on the development of CSA after transcatheter
63 outcomes between monitored anesthesia care (MAC) and general anesthesia (GA) in patients presenting
64 ND & AIMS: Use of monitored anesthesia care (MAC) for gastrointestinal endoscopy has increased in the
71 assifier, named Metabolic Allele Classifier (MAC), that uses flux balance analysis to estimate the bi
72 ons augment the mass absorption coefficient (MAC) of the aerosols by a factor of 2-3 by forming secon
73 enes), microphthalmia-anophthalmia-coloboma (MAC; 86 genes), congenital cataracts and lens-associated
74 ormed a phase III randomized trial comparing MAC with RIC in patients with acute myeloid leukemia or
78 sential role in the membrane attack complex (MAC), which forms a lethal pore on the cellular surface
80 Members of the Mycobacterium avium complex (MAC) are characterized as nontuberculosis mycobacteria a
81 stent growth of Mycobacterium avium complex (MAC) in the lungs indicates continuous infection in MAC
82 for identifying Mycobacterium avium complex (MAC) species and Mycobacterium abscessus subspecies and
83 ycobacteria and Mycobacterium avium complex (MAC) were quantified by qPCR targeting, respectively, at
88 posits complement membrane attack complexes (MAC) on graft endothelial cells (ECs), substantially inc
89 In response to membrane attack complexes (MAC), ZFYVE21 is post-translationally stabilized on MAC+
91 not exceed maximum acceptable concentration (MAC) of 0.003mgkg(-1)bw(-1)day(-1) through daily consump
95 (RIC) instead of myeloablative conditioning (MAC); however, the biology underlying this treatment rem
97 cently reconstituted minimal actin cortices (MACs) and here advanced our assay to investigate effects
98 The reaction utilizes a masked acyl cyanide (MAC) reagent, which enables the one-pot preparation of a
101 (CDC) Zika MAC-ELISA, the InBios ZIKV Detect MAC-ELISA, and the Euroimmun anti-Zika Virus IgM ELISA.
103 at taxa driven to low abundance when dietary MACs are scarce are inefficiently transferred to the nex
106 CRO in two high-risk wards using the direct MAC plate method, recorded ZDs for each sample, and gene
108 ard and accurate approach for discriminating MAC and M. abscessus (sub)species and for detecting clar
109 es continuous infection in MAC lung disease (MAC-LD), but its clinical significance has not been inve
113 omes develops into one MAC chromosome during MAC development, which provides a mechanism of the forma
116 violacea isolates possess the genes encoding MACs, and what phenotypic effect MACs and TBP have on ot
117 ence of bacteria-induced metamorphic events: MACs induce larval settlement; then, particular properti
118 tern, and positive AFS had an OR of 17.7 for MAC-PP, and those with >/=2 of the factors had a 4.5-fol
122 dictors of persistent culture-positivity for MAC (MAC-PP) and its impact on radiographic deterioratio
123 atients with high MAC score category (fourth MAC score quartile) should be considered at high risk fo
125 re frequent and significantly different from MAC: epidermal disarray; pagetoid infiltration of dendri
126 is improved by integrating information from MAC and ONH in advanced glaucoma, suggesting that struct
131 cal properties of MAC revealed heterogeneous MAC precursors and conformations that provide insights i
132 rrent study suggests that patients with high MAC score category (fourth MAC score quartile) should be
136 ow that the role of C5 convertase enzymes in MAC assembly extends beyond the cleavage of C5 into the
137 the lungs indicates continuous infection in MAC lung disease (MAC-LD), but its clinical significance
138 V infection, we show that the CDC and InBios MAC-ELISAs perform comparably to each other, with positi
139 immun ZIKV ELISA to either the CDC or InBios MAC-ELISAs resulted in positive agreement, negative agre
140 have described the structures of individual MAC components and subcomplexes; however, the molecular
142 tion, IFN-gamma-primed human ECs internalize MAC, triggering both endosomal-associated NIK-dependent
145 tudies provide basic molecular insights into MAC assembly and bacterial killing by the immune system.
149 ides linked to cathepsin B in the lysosomes (MACs) can be applied for the treatment of multidrug-resi
150 ) (M(CAAC)) and (MAC)M((I))(N-carbazolyl) (M(MAC)) complexes show coplanar carbene and carbzole ligan
151 rs of persistent culture-positivity for MAC (MAC-PP) and its impact on radiographic deterioration in
152 on the role of mutations in the macrodomain (MAC) and the papain-like protease 2 (PLP2) domain of non
158 mpt success rate in the ICU with the McGrath MAC videolaryngoscope (Medtronic, Minneapolis, MN) accor
161 ar, Baldcypress, and Blue spruce) had median MAC values ranging from 1.4 x 10(-2) m(2) g(-1) to 7.9 x
165 fg (500 nm </= mobility diameter </=950 nm), MAC values in parentheses are the 16(th) and 84(th) perc
167 cificity of the FP-VLP-MAC-ELISA and the NS1-MAC-ELISA were each higher than 80%, with no statistical
170 nt insights into the mechanisms of action of MAC provide an updated framework to therapeutic approach
171 entives to promote appropriate allocation of MAC based on clinically meaningful patient factors.
172 of the first C9 is the kinetic bottleneck of MAC formation, after which rapid C9 oligomerization comp
176 graphy to investigate the pathophysiology of MAC and assess factors associated with disease activity
180 ignificantly associated with the presence of MAC (odds ratio [OR] per triglyceride GRS unit: 1.73; 95
181 e levels was associated with the presence of MAC, a risk factor for clinically significant mitral val
183 layed due to the nonspecific presentation of MAC-PD and radiological findings that overlap with other
184 the structure and biophysical properties of MAC revealed heterogeneous MAC precursors and conformati
186 (IES) are excised, followed by rejoining of MAC-destined sequences, while fragmentation occurs at co
188 should focus on better defining the role of MAC and facility and organizational factors that affect
191 investigated factors associated with use of MAC in an integrated health care delivery system with a
193 ity factors were also associated with use of MAC, although again the magnitude of these associations
198 l settlement; then, particular properties of MACs encoded by a specific locus in P. luteoviolacea ini
199 arried out only on extracted HRMS signals of MACs yield a better characterization of the studied grou
202 n 18-month period, 4,766 (69%) had growth on MAC plates, and 2,500 (36%) met criteria for further eva
203 FYVE21 is post-translationally stabilized on MAC+Rab5+ endosomes in a Rab5- and PI(3)P-dependent mann
204 ure of the MIC chromosomes develops into one MAC chromosome during MAC development, which provides a
206 While P. luteoviolacea biofilms producing MACs stimulate the metamorphosis of the tubeworm Hydroid
208 was documented in 62% of the fourth quartile MAC score (>2700) patients as compared with 31% of the f
212 ar block) with Monitored Anesthesia Care (RA-MAC) or General Anesthesia (GA) for open globe injury re
215 Globe injury repair was performed using RA-MAC in 351/448 (78%) patients and general anesthesia in
216 ed B cells]-inducing kinase) protein on Rab5+MAC+ endosomes, activating noncanonical NF-kappaB signal
217 slocation from endoplasmic reticulum to Rab5+MAC+NIK+ endosomes followed by endosomal NIK-dependent i
218 ts pre-HCT were randomly assigned to receive MAC (n = 135) or RIC (n = 137) followed by HCT from HLA-
220 ) with a myeloablative conditioning regimen (MAC) before allogeneic transplantation in patients with
224 urce-specific mass absorption cross-section (MAC) and wavelength dependence of different BrC componen
227 al valve replacement in patients with severe MAC using an anatomically designed mitral prosthesis.
231 rapy for acute posterior circulation stroke, MAC is feasible and appears to be as safe and effective
233 agnostic yield between phenotypic subgroups: MAC, 8.2% (8 of 98 cases solved); ASDA, 24.8% (28 of 113
234 ds light on the mechanisms by which sublytic MAC causes tumor cell responses and exposes a gene expre
235 rk to therapeutic approaches that can target MAC assembly, signaling, and proinflammatory effects in
238 force microscopy (AFM) imaging to show that MAC proteins oligomerize within the membrane, unlike str
239 bacterium tuberculosis strains and show that MACs predict AMR phenotypes with accuracy on par with me
246 ction, the replicase proteins containing the MAC and PLP2 mutations were more rapidly degraded at the
247 At present, it is not understood how the MAC perturbs the composite cell envelope of Gram-negativ
248 rs (interquartile range, 60-75 years) in the MAC group vs 67 years (interquartile range, 55.5-78.5 ye
251 ses governing rainfall isotope ratios in the MAC region during continental and maritime TC tracks, wi
253 a structural model of C9, as present in the MAC, hints at their putative roles in pore formation or
254 6 patients with MAC-LD, 75 (60%) were in the MAC-PP group; these patients had a higher proportion of
264 rtic valve disease, therefore predisposed to MAC, underwent (18)F-sodium fluoride (calcification acti
265 1 induction distinctly occurs in response to MAC and is detected in human renal and synovial tissues.
266 nterferon-gamma) primes EC responsiveness to MAC by increasing NLRP3, pro-caspase 1, and gasdermin D
267 ree survival and overall survival similar to MAC in patients with MDS or secondary acute myeloid leuk
269 e formation of toxic alkenals, which lead to MACs upon glutathione conjugation and metabolization.
271 se of high relapse incidence with RIC versus MAC (48.3%; 95% CI, 39.6% to 56.4% and 13.5%; 95% CI, 8.
272 he sensitivity and specificity of the FP-VLP-MAC-ELISA and the NS1-MAC-ELISA were each higher than 80
273 ts, the triglyceride GRS was associated with MAC (OR per triglyceride GRS unit: 1.79; 95% CI: 1.32 to
275 r TRM but higher relapse rates compared with MAC, with a statistically significant advantage in RFS w
276 gnificantly prolonged survival compared with MAC-transplanted recipients (TBI of 850 cGy plus cycloph
280 ions of lipid genetic risk scores (GRS) with MAC in 3 large patient cohorts: the Framingham Health St
283 SD] age, 34.5 [6.1] years), 16 patients with MAC (mean [SD] age, 49.6 [17.9] years), and 5 patients w
284 ypes, and Group 2 consisted of patients with MAC and MEL; RCM and dermoscopy were used for lips analy
286 Microbiological persistence in patients with MAC-LD is not uncommon and leads to an increased risk of
289 p, patients who underwent the procedure with MAC had similar rates of successful reperfusion, good cl
290 y using multilevel logistic regression, with MAC use modeled as a function of procedure year, patient
292 rial that compared a busulfan-based RIC with MAC in patients with MDS or secondary acute myeloid leuk
293 ght-emitting diodes (OLEDs) fabricated with (MAC*)Cu(Cz) as a green emissive dopant have high externa
295 ,9-trimethyl-2-azaspiro[4.5]decan-2-ylidene, MAC = 1,3-bis(2,6-diisopropylphenyl)-5,5-dimethyl-4-keto
296 or Disease Control and Prevention (CDC) Zika MAC-ELISA, the InBios ZIKV Detect MAC-ELISA, and the Eur
300 suggest that replacement of the InBios ZIKV MAC-ELISA with the InBios ZIKV 2.0 MAC-ELISA will lead t