ライフサイエンスコーパス: MAS

1 MAS at 4.3 K, DNP, electron decoupling, and short recycl

2 MAS has the advantage of eliminating fat before LC-GC an

3 MAS is used to oxidize cytosolic NADH in mitochondria, a

4 MAS NMR and Fourier transform infrared measurements show

5 MAS spectra yield isotropic chemical shifts for each cry

6 dipolar tensors and peak intensities from 3D MAS NMR spectra of wild-type and the A92E and G94D CypA

7 , (13)C-(13)C, and (1)H-(15)N 2D, 3D, and 4D MAS spectra, all of which show cross-peak doubling.

8 bility to mediate fast diffusion of VX and a MAS centrifugation effect.

9 giotensin 1-7 and alamandine, which activate MAS proto-oncogene and MAS-related D receptors, respecti

10 , but their absence did not otherwise affect MAS manifestations.

11 n fine structure (EXAFS) analysis and (27)Al MAS NMR spectroscopy supported by DFT-based molecular dy

12 ldren of the Multizentrische Allergiestudie (MAS) and 766 children of the Protection against allergy:

13 We used an MAS model established in mice transgenic for human IL-6

14 ion met 44% and 81% of modified HLH-2004 and MAS criteria, respectively.

15 tokine production differed between MIS-C and MAS.

16 ncluding gastrin-releasing peptide (GRP) and MAS-related GPCR member A3 (MRGPRA3), in nociceptors exp

17 e gained through treatment trials of HLH and MAS in childhood may inform study design for therapy of

18 and laboratory features distinct from KD and MAS.FUNDINGThis work was supported by the National Insti

19 enorca (Spain), BAMSE (Sweden), LISAplus and MAS (Germany), and PIAMA-NHS (the Netherlands).

20 ndine, which activate MAS proto-oncogene and MAS-related D receptors, respectively.

21 ammation and hyperinflammation in sepsis and MAS, we sought to study regulatory mechanisms underlying

22 ulated monocytes from patients with SJIA and MAS, including upregulated CD163 mRNA and increased CD64

23 ge populations in disorders such as SJIA and MAS.

24 arameters, and the combination of static and MAS analyses, can aid investigations of mixed carbonates

25 Here, we apply MAS NMR to directly probe the dynamic histone protein re

26 The results suggest a requirement for ARALAR-MAS in priming pyruvate entry in mitochondria as a step

27 y condition tested Ca2+ activation of ARALAR-MAS was required to fully stimulate coupled respiration

28 ry and oxidation of L-lactate through ARALAR-MAS pathway is required for its neuroprotective function

29 Assessing MAS-induced activation of brain networks interconnected

30 There are several reports of SJIA-associated MAS dramatically benefiting from anakinra, a recombinant

31 At MAS frequencies above 20 kHz, it was possible to record

32 irst demonstration of recovery times between MAS-NMR transients being governed by short electron T(1)

33 No differences in brain uptake between MAS participants and controls were detected-a finding th

34 Female mice were impacted by MAS in an estrous cycle-dependent manner: MAS impaired h

35 ted impaired mice from those not impaired by MAS.

36 decalin has been studied using in situ (13)C MAS NMR spectroscopy.

37 ed and Raman spectroscopies, (31)P and (13)C MAS NMR, N(2) adsorption isotherms, and X-ray diffractio

38 Most commonly, MAS-DNP is based on the use of nitroxide biradicals as p

39 es, mediated by the activity of the complete MAS, and that intramitochondrial Ca(2+) accounts for the

40 Of note, the complete MAS, as applied here, included besides its classical NAD

41 ts as a function of biradical concentration, MAS frequency, temperature, and microwave power is repor

42 med for the first time under MAS conditions (MAS rate 10 kHz).

43 A pronounced ligand effect was found, and CP MAS NMR experiments enabled us to probe important differ

44 ipitates is unequivocally proven by (13)C CP MAS NMR spectroscopy.

45 We also apply 1D (13)C CP MAS, 1D (15)N CP MAS, and 2D (13)C-(13)C DARR experiment

46 We also apply 1D (13)C CP MAS, 1D (15)N CP MAS, and 2D (13)C-(13)C DARR experiments to SNa15 sample

47 cross polarization magic angle spinning (CP MAS) NMR spectroscopy.

48 etween transformations, solid-state (13)C CP-MAS NMR can be employed to directly monitor phenyl rotat

49 complete, as assessed by FT-IR and (13)C CP-MAS NMR spectroscopy and demonstrates (a) the first chem

50 FTIR and (13)C and (15)N CP-MAS NMR of fresh and SO2 adsorbed modified G3 on PME con

51 ngle spinning nuclear magnetic resonance (CP-MAS NMR) spectroscopy, and atom probe tomography (APT).

52 cross-polarization magic angle spinning (CP-MAS) NMR spectroscopy of the framework and of its (13)C-

53 cross-polarization magic-angle-spinning (CP-MAS) NMR.

54 DFT, CASSCF, QT-AIM, ELF) and solid-state CP-MAS (13)C NMR spectroscopic analysis indicate that 3 is

55 ization magic angle spinning solid-state (CP-MAS) NMR spectroscopy, powder and single-crystal X-ray d

56 Structural assignments are confirmed by CP/MAS (13)C NMR, Raman, and XPS spectroscopy.

57 (13)C CP/MAS NMR spectra show that the Fe(CO)3 moiety in polycrys

58 from spectral deconvolution of the (13)C CP/MAS spectra and the results has shown that all the extra

59 g complementary spectroscopic techniques (CP/MAS (13)C NMR, Raman, FT-IR, and XPS) and high-resolutio

60 HR-CS MAS investigations revealed that the complexes were high

61 Analysis using HR-CS MAS was accomplished by monitoring the CaF molecule, whi

62 rce molecular absorption spectrometry (HR-CS MAS) for F determination and electrothermal vaporization

63 Here, we detail MAS NMR experiments and sample labeling schemes designed

64 in, we make use of advances in (1)H-detected MAS NMR to describe the dynamics of the membrane domain

65 nuclear polarization (DNP) and (1)H-detected MAS techniques.

66 0(6) s(-1), as determined from the deuterium MAS line shapes.

67 er, in two-dimensional and three-dimensional MAS NMR spectra the CL-bound cyt-c displays a spectral r

68 Two-dimensional DNP MAS NMR of the silica-bound peptide and solution NMR of

69 ernative sample preparation strategy for DNP MAS ssNMR studies of lipid membranes and integral membra

70 Specifically, DNP MAS ssNMR experiments at 600 MHz/395 GHz on KL4 reconsti

71 In this study we employ MAS (1)H NMR to probe the phase transitions of both solv

72 The employed MAS NMR sample conditions cause a previously noted subst

73 ta obtained from high-field and DNP-enhanced MAS NMR spectroscopy together with time-resolved optical

74 simultaneous microwave-assisted extraction (MAS) and unsaponifiable extraction, followed by on-line

75 establishes the power of DNP-enhanced (19)F MAS NMR spectroscopy for structural characterization of

76 In unprecedented solid-state (19)F MAS NMR studies, the templating anions, engaged in anion

77 Fast MAS (1)H{(195)Pt} dipolar-HMQC and S-REDOR experiments w

78 Here, it is demonstrated that fast MAS and proton detection with the D-RINEPT pulse sequenc

79 Optimal sensitivity attained due to the fast MAS probe technologies enabled the assignment of the loc

80 , used as endogenous polarization agents for MAS-DNP, in enabling the detection of (17)O at a natural

81 A catalogue of favourable SNP markers for MAS and a list of candidate genes are provided.

82 13 new stable mono- and dinitroxide PAs for MAS DNP NMR where this principle is demonstrated.

83 nked to these QTLs are potential targets for MAS against Phytophthora crown rot in C. moschata.

84 d on 8bp deletion in BADH2 as unsuitable for MAS in rice cultivars under study.

85 These data demonstrate that both fulminant MAS and hemophagocytosis can arise independently of IFNg

86 molecular absorption spectrometry (HR-CS GF MAS) via molecular absorption of phosphorus monoxide.

87 iments at multiple field strengths, and (1)H MAS NMR experiments, these data indicate that this secon

88 nce complicates the analysis of in situ (1)H MAS NMR investigations due to water's ease of solidifica

89 d using deuterium magic angle spinning ((2)H MAS) line shape and spin-lattice relaxation measurements

90 xagonal packing is also consistent with (1)H-MAS NMR spectra of the L(o) phase, NMR diffusion experim

91 HR-MAS (1)H NMR and neutron scattering experiments reveal t

92 HR-MAS NMR profiling demonstrates cancer-specific metabolic

93 HR-MAS was performed on pre-treatment frozen tumour tissue

94 evelopment of these molecular agents, and HR-MAS NMR spectroscopy appears to be a very interesting to

95 We measured metabolites by HR-MAS (1)H NMR spectroscopy and DNA cytosine modifications

96 gal forces experienced under conventional HR-MAS frequencies of several kilohertz.

97 features limit the usefulness of current HR-MAS approaches for fragile samples.

98 This study shows the potential of (1)H HR-MAS as a rapid method for probing metabolomic profiles a

99 (1)H HR-MAS NMR metabolite profiling was achieved from a small s

100 ore, we analyzed previously acquired (1)H HR-MAS NMR spectra of separated cortex and medulla samples

101 (1)H HR-MAS NMR spectroscopy was used to track the metabolic cha

102 igh-resolution magic angle spinning ((1)H HR-MAS) nuclear magnetic resonance (NMR) spectroscopy in co

103 n magic angle spinning spectroscopy ((1)H HR-MAS).

104 ration of the sample, measurement time in HR-MAS NMR is very short.

105 rd disposable inserts classically used in HR-MAS NMR-based metabolomics.

106 pand the applicability and reliability of HR-MAS NMR spectroscopy.

107 this study, we utilized a method based on HR-MAS NMR spectroscopy with slice localization (SLS) to ac

108 full protocol for acquiring high-quality HR-MAS NMR spectra of biological tissues at low spinning ra

109 The performance of the slow HR-MAS NMR procedure is demonstrated on conventional (liver

110 00 MHz and suggest that high-quality slow HR-MAS spectra can be expected at higher magnetic fields us

111 gic-angle-spinning (1)H NMR spectroscopy (HR-MAS NMR) is a well-established technique for assessing t

112 nuclear magnetic resonance spectroscopy (HR-MAS) and their prognostic potential investigated.

113 1)H high resolution-magic angle spinning (HR-MAS) NMR spectroscopy of apple pulp was performed before

114 High-resolution magic-angle spinning (HR-MAS) nuclear magnetic resonance (NMR) is an essential to

115 1)H high-resolution magic-angle spinning (HR-MAS) nuclear magnetic resonance (NMR) spectroscopy have

116 y a high-resolution magic angle spinning (HR-MAS) proton ((1)H) NMR spectroscopic examination of inta

117 -MACS), a simple conversion of a standard HR-MAS probe to muHR-MAS.

118 This study demonstrates that HR-MAS SLS combined with multivariate statistics has the po

119 Samples were subjected to HR-MAS NMR spectroscopic profiling and acquired spectral da

120 cterize metabolic properties in CRC using HR-MAS NMR spectroscopy.

121 ralar/AGC1 knockout neurons reflect impaired MAS activity and limited mitochondrial pyruvate supply.

122 s-effect DNP enhancements can be achieved in MAS experiments on frozen solutions by simply incorporat

123 onist, but the utility of other biologics in MAS is not clear.

124 Mean change in MAS score from baseline at week 4 in the PTMG was -0.3 (

125 The recent developments in MAS NMR instrumentation and methodologies opened new vis

126 igmentation is an underrecognized finding in MAS and presents later in development compared with the

127 ay control catastrophic hyperinflammation in MAS.

128 riants in other genes previously observed in MAS.

129 autoinflammatory disease spectrum to include MAS and suggests new targets for therapy.

130 In an adjuvant-induced MAS model, excess IL-18 promoted immunopathology, wherea

131 We have initiated MAS and large-scale planting of elite dura and pisifera

132 als (T(1e) =40+/-6 ms, 40 mM trityl, 4.0 kHz MAS, 4.3 K).

133 o fully protonated proteins that, at 100-kHz MAS and above, spectral resolution is high enough to det

134 enylallyl dissolved in o-terphenyl at 40 kHz MAS.

135 and R1rho relaxation rates at fast (60 kHz) MAS and high magnetic field (1 GHz), we were able to des

136 uman IL-6 (IL-6TG mice) challenged with LPS (MAS mice).

137 by MAS in an estrous cycle-dependent manner: MAS impaired hippocampus-dependent spatial memory in ear

138 onversion of a standard HR-MAS probe to muHR-MAS.

139 formations were assessed using (15)N multiCP-MAS NMR spectroscopy, providing the first quantitation o

140 ion based 2D and 3D (13)C-(13)C, (13)C-(15)N MAS NMR experiments for rigid residues along with J-base

141 (23)Na MAS NMR spectra of sodium-oxygen (Na-O2) cathodes reveal

142 (2)H NMR MAS spectra and T1 relaxation times obtained from the de

143 roscopy, neutron diffraction, and (7) Li NMR MAS and PFG spectroscopy to show that increasing the Cl(

144 (17)O MAS NMR spectra for these systems provide insights into

145 tion of respiration occurs in the absence of MAS through Ca(2+) influx through the mitochondrial calc

146 nd ligands, in which case the application of MAS NMR dipolar recoupling requires the low temperatures

147 ible primarily because of the development of MAS rotors that spin at frequencies of 40 to 60 kHz or h

148 The diagnosis of MAS is most commonly a clinical diagnosis because mutati

149 n some cases may aid in earlier diagnosis of MAS.

150 Here we examined the effects of MAS on female mice and probed the role of hormonal fluct

151 established profound and enduring effects of MAS on memory in males.

152 hould be recognized as a clinical feature of MAS.

153 atients had other characteristic findings of MAS including hyperfunctioning endocrinopathies, polyost

154 n, the estrous cycle modulates the impact of MAS on spatial memory, and fluctuating physiological lev

155 Clinical manifestations of MAS in a given individual, including fibrous dysplasia,

156 N-gamma neutralization in an animal model of MAS.

157 Murine models of MAS and HLH illustrate that interferon-gamma (IFNgamma)

158 y play a central role in the pathogenesis of MAS, the role of other cytokines is still not clear.

159 The clinical phenotype of MAS is variable because of mosaicism, but oral pigmentat

160 The rapid progress of MAS DNP has been largely enabled through the understandi

161 thogenic role of IFN-gamma in the setting of MAS.

162 ther fibrous dysplasia and other symptoms of MAS, including neuropsychiatric impairments, are associa

163 nal fluctuations during the estrous cycle on MAS-induced memory problems and the underlying brain net

164 GOT2 deficiency that may also hold for other MAS defects.

165 y (CV = 4.8-7.0%) contributed to the overall MAS%MVC variability.

166 However, (31)P MAS NMR spectra of analyzed series display a higher numb

167 d P(OGe)4 environments are expected in (31)P MAS NMR spectra of R3c NASICON samples.

168 (31)P MAS NMR using TMPO shows probe molecules interacting wit

169 -glycero-3-phosphocholine liposomes by (31)P MAS NMR.

170 Moreover, 2D (31)P-(31)P MAS radio frequency-driven recoupling NMR indicates the

171 eous solvent in the small and densely packed MAS NMR samples.

172 Clinically and pathologically, MAS bears strong similarity to hemophagocytic lymphohist

173 ld (B0 = 3 T) (13)C{(1)H} cross-polarization MAS NMR, carbamate is confirmed through splitting of the

174 angle spinning dynamic nuclear polarization (MAS DNP) has allowed atomic-level characterization of ma

175 angle spinning-dynamic nuclear polarization (MAS-DNP) has developed as an excellent approach for boos

176 ically induced dynamic nuclear polarization) MAS (magic angle spinning) NMR demonstrates that indeed

177 /(13)C labeling and with deuterated protein, MAS at omegar/2pi = 60 kHz, omega0H/2pi = 1000 MHz, and

178 let GP1balpha and G-protein-coupled receptor MAS effectively bound Ig21 by displacing Ig20 from autoi

179 mouse models and in a patient with recurrent MAS.Conclusions: Our data indicate that IL-18 (but not I

180 mouse models and in a patient with recurrent MAS.Measurements and Main Results: Peripheral blood and

181 c-angle spinning nuclear magnetic resonance (MAS NMR) and Fourier-transform infrared (FT-IR) spectros

182 c-angle spinning nuclear magnetic resonance (MAS NMR) spectroscopy and first-principles density funct

183 c angle spinning nuclear magnetic resonance (MAS NMR) spectroscopy, XRD, FT-IR spectroscopy, and N2 p

184 ngle solid-state nuclear magnetic resonance (MAS SS-NMR) spectroscopy establish that alpha-Syn adopts

185 ning solid-state nuclear magnetic resonance (MAS SSNMR) have experienced a remarkable development in

186 ning solid-state nuclear magnetic resonance (MAS ssNMR) spectroscopy are used to gain insight into th

187 Angle Spinning Nuclear Magnetic Resonsance (MAS-NMR) spectroscopy, demonstrated increased abundance

188 assessed using the modified Ashworth Scale (MAS), Myotonometry and repeated passive stretch techniqu

189 nge in muscle tone (Modified Ashworth Scale [MAS]) in the PTMG from baseline to 4 weeks.

190 lerance genes and marker assisted selection (MAS) can accelerate wheat breeding for this trait.

191 l be valuable for marker-assisted selection (MAS) programs to rapidly introgress G. barbadense phytoc

192 ful for potential marker-assisted selection (MAS) to control sex-ratio in GIFT tilapia to suppress un

193 esistance through marker-assisted selection (MAS).

194 of glycolysis and malate-aspartate shuttle (MAS) genes.

195 a component of the malate-aspartate shuttle (MAS), is stimulated by modest increases in cytosolic Ca(

196 tudied the role of malate-aspartate shuttle (MAS)-dependent substrate supply in OXPHOS responses to c

197 y step in the malate-aspartate NADH shuttle, MAS.

198 nd in the gel as can be seen from the (29)Si MAS NMR spectra.

199 Using natural abundance (29)Si MAS NMR spectroscopy with CPMG acquisition and standard

200 ied molecular sieves was monitored by (29)Si-MAS NMR, transmission electron micrographs, X-ray diffra

201 Spider major ampullate gland silks (MAS) vary greatly in material properties among species b

202 NMR properties of water in detail by in situ MAS NMR over a wide temperature range.

203 A multiplex allele-specific (MAS) assay has been developed for the detection of HIV-1

204 ) achieves highest Mean Average Specificity (MAS), a scalar measure for ROC curve, of 0.97 (0.96).

205 A new in situ magic angle spinning (MAS) (7)Li nuclear magnetic resonance (NMR) strategy all

206 erformance of TIDE for magic angle spinning (MAS) [(13)C,(13)C]-DARR NMR spectra of single- and multi

207 pectroscopy under fast magic angle spinning (MAS) and dynamic nuclear polarization surface enhanced N

208 ed by 60 kHz ultrafast magic angle spinning (MAS) and enable the analysis of milligram samples.

209 id-state NMR with fast magic-angle spinning (MAS) at high magnetic fields ((1)H Larmor frequency of 8

210 sed static in situ and magic-angle spinning (MAS) ex situ (13)C nuclear magnetic resonance (NMR) to e

211 -(13)C solid-state NMR magic angle spinning (MAS) experiment is presented and demonstrated on the mic

212 luding both static and magic-angle spinning (MAS) experiments.

213 y measuring RDCs using magic-angle spinning (MAS) in combination with dipolar recoupling methods.

214 om CypA dependence, by magic-angle spinning (MAS) NMR and molecular dynamics (MD).

215 le-quantum solid-state magic-angle spinning (MAS) NMR and small-angle neutron scattering (SANS) were

216 Utilizing (17)O magic-angle spinning (MAS) NMR at multiple magnetic fields (17.6-35.2 T/750-15

217 n time (T(1e) ) during magic angle spinning (MAS) NMR by observation of DNP-enhanced NMR signals (T(1

218 is combined with (1)H magic angle spinning (MAS) NMR detection, absolute quantification of water in

219 ion by proton-detected magic-angle spinning (MAS) NMR has focused on highly deuterated samples, in wh

220 )-enhanced solid-state magic-angle spinning (MAS) NMR in combination with light-induced cryotrapping

221 el characterization by magic angle spinning (MAS) NMR of the muscle isoform of human cofilin 2 (CFL2)

222 -(13)C and (13)C-(15)N magic angle spinning (MAS) NMR spectra.

223 signal intensities in magic-angle spinning (MAS) NMR spectra.

224 )O, (27)Al, and (71)Ga magic angle spinning (MAS) NMR spectroscopy and density-functional theory (DFT

225 Magic Angle Spinning (MAS) NMR spectroscopy is a powerful method for analysis

226 Subsequently, magic-angle spinning (MAS) NMR spectroscopy with sensitivity enhancement by dy

227 ion intermediate using magic angle spinning (MAS) NMR spectroscopy.

228 We report a magic angle spinning (MAS) NMR structure of the drug-resistant S31N mutation o

229 Magic angle spinning (MAS) NMR studies of amyloid and membrane proteins and la

230 s and multidimensional magic angle spinning (MAS) NMR techniques at high magnetic fields, providing v

231 recent developments in magic angle spinning (MAS) NMR technology have made it possible to spin solid

232 ing dipolar recoupling magic angle spinning (MAS) NMR.

233 amics, and solid-state magic-angle spinning (MAS) nuclear magnetic resonance (NMR) is a unique method

234 esonance assignment of magic angle spinning (MAS) nuclear magnetic resonance (NMR) spectra of 5-30 kD

235 ure (EXAFS) and (27)Al magic angle spinning (MAS) nuclear magnetic resonance (NMR) spectroscopies in

236 (6)Li magic angle spinning (MAS) nuclear magnetic resonance (NMR) spectroscopy is th

237 (13)C solid-state magic-angle spinning (MAS) nuclear magnetic resonance (NMR) spectroscopy, supp

238 r sample, by combining magic-angle spinning (MAS) nuclear magnetic resonance (NMR) spectroscopy, tail

239 ionally, fast (25 kHz) magic-angle spinning (MAS) provides optimal sensitivity and resolution.

240 apidly with increasing magic angle spinning (MAS) rates.

241 ata from phosphorus-31 magic angle spinning (MAS) solid state NMR spectroscopy, bolstering the struct

242 ear polarization (DNP) magic-angle spinning (MAS) solid-state NMR (ssNMR) spectroscopy has the potent

243 Although magic angle spinning (MAS) solid-state NMR is a powerful technique to obtain a

244 Multidimensional magic angle spinning (MAS) solid-state NMR of uniformly (13)C,(15)N-labeled pr

245 a labeling scheme for magic angle spinning (MAS) solid-state NMR that is based on deuteration in com

246 ear polarization (DNP) magic angle spinning (MAS) spectra at 14.1 T on HIV-1 capsid protein (CA) asse

247 ear polarization under magic angle spinning (MAS-DNP) could be used to dramatically increase the sens

248 high-resolution (11)B magic-angle-spinning (MAS) and (105)Pd static solid-state NMR nuclear magnetic

249 Magic-angle-spinning (MAS) solid-state NMR (ssNMR) spectroscopy allows for the

250 use (14)N, (2)H, (13)C, and (1)H solid-state MAS NMR to elucidate cation reorientation dynamics, micr

251 (87)Rb, (39)K, (13)C, and (14)N solid-state MAS NMR to probe microscopic composition of Cs-, Rb-, K-

252 Using solid-state MAS NMR, we demonstrate the atomic-level interaction bet

253 ge in membrane-bound proteins in solid-state MAS NMR.

254 ization to PBDA, demonstrated by solid-state MAS-NMR, Raman, and optical absorption spectroscopy.

255 nsist of concurrent multiple acute stresses (MAS).

256 activity in macrophage activation syndrome (MAS) and poor clinical outcomes in severe inflammatory a

257 is (HLH) and macrophage activation syndrome (MAS) are life-threatening hyperinflammatory syndromes ty

258 HLH-2004 and macrophage activation syndrome (MAS) criteria.

259 Macrophage activation syndrome (MAS) is an acute episode of overwhelming inflammation ch

260 hogenesis of macrophage activation syndrome (MAS) is not clearly understood: a large body of evidence

261 sis (HLH) or macrophage activation syndrome (MAS) occur after chimeric antigen receptor T cell (CAR T

262 which have a macrophage activation syndrome (MAS)-like disease.

263 is (HLH) and macrophage activation syndrome (MAS).

264 HLH-sibling macrophage activation syndrome (MAS).

265 r flares and macrophage activation syndrome (MAS).

266 s (SJIA) and macrophage activation syndrome (MAS).

267 ase (KD) and macrophage activation syndrome (MAS).RESULTSTwenty-eight patients fulfilled the case def

268 McCune-Albright syndrome (MAS) is a mosaic disorder arising from gain-of-function

269 McCune-Albright syndrome (MAS), a mosaic condition associated with cafe au lait pi

270 The results presented show that MAS-DNP from paramagnetic metal ion dopants provides an

271 The MAS NMR approach reported here establishes the foundatio

272 his approach facilitates and accelerates the MAS NMR assignment process, shortening the spectral acqu

273 findings show that PGC-1alpha1 activates the MAS in skeletal muscle, supported by kynurenine cataboli

274 sstalk between kynurenine metabolism and the MAS may have important physiological and clinical implic

275 tion of the cytoskeletal organization at the MAS.

276 es 11-42 and 69-77, which are visible in the MAS solid-state NMR spectra, show (13)Calpha chemical sh

277 We have optimized the MAS assay to determine subtype B DRMs in dried blood spo

278 elderly Australians age 70 to 90 years (the MAS [Sydney Memory and Ageing Study], n = 1,037).

279 n strongly reduced IL-18 serum levels in two MAS mouse models and in a patient with recurrent MAS.Con

280 hout JAK/STAT inhibition was analyzed in two MAS mouse models and in a patient with recurrent MAS.Mea

281 ising potential of proton-detected ultrafast MAS NMR for monitoring structural and dynamic changes ca

282 ted NMR measurements on bone under ultrafast MAS conditions to provide atomistic-level elucidation of

283 r recoupling) pulse sequence under ultrafast MAS.

284 uitably combines proton-detection, ultrafast-MAS and multiple frequency dimensions to overcome this l

285 ies to be performed for the first time under MAS conditions (MAS rate 10 kHz).

286 Using MAS solid-state NMR, we studied the fibril structure of

287 t only demonstrates the possibility of using MAS-DNP to greatly facilitate the acquisition of 2D (29)

288 In agreement with MAS NMR data, proteolysis experiments performed on the f

289 regulatory factor 5 (IRF5), associated with MAS, participated in TLR7-driven iHPC differentiation.

290 T scans were performed on 6 individuals with MAS (3 for brain scans and 6 for whole-body scans) and 9

291 and in cultured cells from individuals with MAS but not in humans with fibrous dysplasia.

292 splasia in the periphery of individuals with MAS; no uptake was observed in the bones of healthy cont

293 In addition, mice with MAS had a significant increase in numbers of liver CD68(

294 Mice with MAS showed a significant upregulation of the IFN-gamma p

295 Mice with MAS treated with an anti-IFN-gamma antibody showed a sig

296 In mice with MAS, treatment with the anti-IFN-gamma antibody signific

297 lso found in livers and spleens of mice with MAS.

298 m uptake was noted between participants with MAS and healthy controls.

299 We present 4 patients with MAS who developed oral mucosal pigmentation during child

300 been observed specifically in patients with MAS, making it a promising therapeutic target, but how I