ライフサイエンスコーパス: MBL

1 MBL and ficolin-2 were present in human carotid plaques,

2 MBL binding occluded the autologous NAb epitope on the B

3 MBL bound to CC in a calcium-dependent manner whereas fi

4 MBL can be categorized as either low count or high count

5 MBL deficiency has been linked to a more severe course o

6 MBL is a C-type lectin that recognizes oligosaccharides

7 MBL ranged from 0 to 2.85 mm: 75.9% of mesial sites and

8 MBL was assessed.

9 MBL was calculated from the difference between initial a

10 MBL was significantly (P <0.05) greater in open-flap com

11 MBL was significantly higher in group 1 as compared with

12 MBL zinc fingers are the most highly conserved portion o

13 MBL-A was detected as early as 3.5 d of pregnancy, and M

14 MBL-A was observed in the implantation sites of CBA/J x

15 MBL-GS muPADs offer direct quantitative analysis of vola

16 MBL-GS muPADs were designed to make fabrication of the d

17 nd deficient (26.3 versus 17.1%, p = 0.0361) MBL pathway functions were observed statistically more f

18 -M-15 and KPC-2, subclass B1 NDM-1 and VIM-2 MBLs, and the class C P. aeruginosa AmpC.

19 triuretic peptide], TSP2 [thrombospondin-2], MBL [mannose-binding lectin]; and 3 with lower risk: Erb

20 plant, respectively, when compared with <25% MBL.

21 by whole-exome sequencing of 456 CLL and 43 MBL patients, are either truncating or affect conserved

22 eri-implantitis defects >=50% and 25% to 50% MBL were 18.6 and 8.86 times more likely to lose the imp

23 t B. burgdorferi N40 needle-infected C57BL/6 MBL deficient mice harbored significantly higher B. burg

24 was an outlier, and the IMP isolates and 6/7 MBL-negative isolates clustered separately from the main

25 A MBL-GS muPAD consists of three layers: "donor layer", "s

26 ficient concentration of biologically active MBL in body fluids is an indicator of proper function of

27 of maintenance visits significantly affected MBLs from Tb to T1.

28 rs are micromolar competitive betaLIs of all MBL classes in vitro, with Kis of 6-15 microM or 36-84 m

29 hETHE1 contains an alphabetabetaalpha MBL-fold, which supports metal-binding by the side chain

30 harbor a highly conserved alphabetabetaalpha MBL-fold domain and were first described as inactivators

31 Among MBL-harboring isolates, the impact of EDTA on MICs was d

32 s failed to demonstrate an association among MBL and confounding factors.

33 rent classifications of susceptibility among MBL-harboring Enterobacteriaceae The addition of EDTA at

34 rent classifications of susceptibility among MBL-harboring isolates.

35 An MBL inhibitor could restore the effectiveness of beta-la

36 racterizing quantum critical behaviour in an MBL system requires probing its entanglement over space

37 AL [P <0.0001], PD >/=4 mm [P <0.0001], and MBL [P <0.0001]) was significantly higher among WPs and

38 t morphology (P = 0.02), PD (P = 0.003), and MBL (P = 0.01) were significantly correlated with the gr

39 ; P = 0.004), PD (OR = 1.63; P = 0.024), and MBL (OR = 1.35; P = 0.010) were significantly associated

40 05], AL [P <0.05], PD >/=4 mm [P <0.05], and MBL [P <0.05]) were significantly higher in smokers than

41 NRX-5133 binds to the class D SBL OXA-10 and MBL NDM-1.

42 nt positive correlation between IL-1beta and MBL in group 2 (P = 0.0031).

43 we examined the deposition of ficolin-2 and MBL in human carotid plaques by immunohistochemistry and

44 activated on CC by binding of ficolin-2 and MBL in vitro, resulting in activation and deposition of

45 n the scores of PI, BOP, PD, clinical AL and MBL when SRP was performed with/without adjunct PT.

46 difference in number of MT, clinical AL, and MBL among all groups.

47 ept for elevated levels of factor D, Bb, and MBL.

48 0.0198) and IL-1beta (P = 0.0047) levels and MBL in group 1; and a significant positive correlation b

49 ng lectin (MBL) associated protein (MAP) and MBL associated serine protease (MASP) are scarcely inves

50 by the mandibular cortical index (MCI), and MBL and 2) to assess how various systemic diseases, peri

51 e thickness at time of implant placement and MBL with >/=12-month follow-up.

52 detected as early as 3.5 d of pregnancy, and MBL-A deficiency prevented pregnancy loss in the abortio

53 combinant mannose binding lectins (MBLs) and MBLs in sera of both murine and human origin bound to so

54 ng modes for bicyclic boronates for SBLs and MBLs imply scope for side-chain optimization.

55 ty of bicyclic boronates to inhibit SBLs and MBLs via binding of a tetrahedral (sp(3)) boron species.

56 6-15 microM or 36-84 microM for subclass B1 MBLs (IMP-1 and BcII, respectively), and 10-12 microM fo

57 t closely resemble beta-lactam binding to B1 MBLs, but feature an unprecedented disruption of the D12

58 dominates interactions with the monozinc B2 MBL Sfh-I, with the thiol uninvolved.

59 Against the B2 MBL Sfh-I, the l-BTZ enantiomers exhibit 100-fold lower

60 5133 activity against IMP-1 and tested B2/B3 MBLs was lower/not observed.

61 evations of ADE levels of C4b, factor D, Bb, MBL, C3b and C5b-9 terminal C complex, and depressions o

62 for decades except for normalization of Bb, MBL, and CD59 in late chronic mtTBI (n = 15).

63 kdown of conventional thermodynamics because MBL systems do not thermalize and show nonergodic time e

64 seed liquor-based beverage with maqui berry (MBL), characterising its bioactive and volatile composit

65 in regenerated sites (P <0.001) and between MBL and a previous history of periodontitis (P <0.05).

66 ificant associations were also found between MBL and placement of implants in regenerated sites (P <0

67 umenting a noncanonical binding mode between MBL and beta2-GPI.

68 , a significant binding was observed between MBL and isolated domains II and IV of beta2-GPI, whereas

69 s related to the 'classical' di-zinc binding MBL hydrolases involved in antibiotic resistance, but ha

70 linical parameters, inflammatory biomarkers, MBL, and SIRT1 levels were measured at baseline and at p

71 Both MBL and MCI were assessed from panoramic radiographs.

72 sorbent assays (ELISAs) for BP180 and BP230 (MBL International), immunoglobulin A (IgA) A and immunog

73 alpha-Methylene-gamma-butyrolactone (MBL), a naturally occurring and biomass-sourced bifuncti

74 While regulation of specific target exons by MBL/MBNL has not been broadly conserved across these spe

75 dly active NAb epitopes was also impaired by MBL binding, which could have substantial implications f

76 CD4-MBL CAR-T cells displayed potent lytic and functional re

77 CD4-MBL CAR-T cells were unresponsive to cell-free HIV or co

78 g lectin (MBL) to target native HIV Env (CD4-MBL CAR).

79 M-1) inhibited the cytolytic response of CD4-MBL CAR-T cells to Env-expressing cell lines and HIV-inf

80 Thus, CD4-MBL CAR-T cells are unable to eliminate the FDC-associat

81 Cross-class MBL inhibition therefore arises from the unexpected vers

82 zinc 1 and zinc 2 binding sites in classical MBLs.

83 amino acid variant data on a major clinical MBL, VIM-2, by measuring the effect of thousands of VIM-

84 bleomycin-injured lungs of mice, collectins MBL and SP-D were endocytosed and routed for lysosomal d

85 s, IMN can develop in patients with complete MBL deficiency, with complement activated mainly by the

86 otease-pattern recognition receptor complex, MBL-associated serine protease (MASP)-3/collectin-L1/K1

87 Although individuals with both high-count MBL and CLL Rai stage 0 are at increased risk of infecti

88 High-count MBL is distinguished from Rai 0 CLL based on whether the

89 unt MBL rarely progresses to CLL, high-count MBL progresses to CLL requiring therapy at a rate of 1%

90 istics distinguish low-count from high-count MBL.

91 Low-count MBL can be detected in approximately 5% of adults over t

92 Whereas low-count MBL rarely progresses to CLL, high-count MBL progresses

93 ere associated with diminished and deficient MBL pathway function, respectively.

94 icrofluidic paper-based analytical devices" (MBL-GS muPADs).

95 ion cut-off level associated with diminished MBL pathway function in a group of 201 individuals.

96 , BOP, PD, clinical AL and mesial and distal MBL) were measured on all teeth except third molars at b

97 Four donors (2.7%) had 2 distinct MBL clones.

98 Despite many biochemical studies in diverse MBLs, molecular understanding of the roles of residues i

99 Active-site architecture divides MBLs into three classes (B1, B2, and B3), complicating d

100 In conclusion, when donor MBL was approximated by subsequent donor CLL diagnosis,

101 influence of soft tissue thickness on early MBL around dental implants.

102 e the influence of tissue thickness on early MBL.

103 molecular mechanisms enable uPARAP to engage MBL immobilized on the surface of pathogens, thereby exp

104 mediated by metallo-beta-lactamase enzymes (MBLs).

105 y using logistic regression, controlling for MBL cut-off, age, gender, and age and gender interaction

106 ved across these species, genes enriched for MBL/MBNL binding sites in their introns may play roles i

107 he need for new inhibitors, particularly for MBLs; the likely impact of new beta-lactam:inhibitor com

108 M) was identified to be highly selective for MBLs when compared to other Zn(II) metalloenzymes.

109 nd the procoagulant effects of the beta2-GPI/MBL complex may contribute to amplify similar activities

110 t pose a risk for the development of greater MBL.

111 An uncharacterized member of the human MBL family, MBLAC2, was detected in multiple palmitoylpr

112 use in combination with the mCIM to identify MBL-producing Enterobacteriaceae.

113 and matched immunofluorescence assays (IFAs; MBL Bion, Des Plaines, IL) in 220 HCWs categorized by AC

114 this study, we investigated whether impaired MBL pathway function, represented by reduced serum MBL c

115 Peri-implant MBLs were frequently located in a zone within 1 mm of th

116 bony defects of >/=5 mm regarding change in MBL.

117 study was powered to detect a difference in MBL of >0.9 mm.

118 ohn's disease patients have an impairment in MBL-MASP functional activity and that this defect is ass

119 gnificantly correlated with an impairment in MBL-MASP functional activity.

120 Loss of FDC localization in MBL-deficient mice or via immunogen deglycosylation sign

121 pracrestal tissue height plays a key role in MBL than mucosal thickness in tissue level implant.

122 rsely affecting the development of increased MBL are a previous history of periodontitis and especial

123 INTERPRETATION: MBL is common in both Uganda and the UK, but the substan

124 ctivity is comparable to those of well-known MBLs from pathogenic sources (e.g. NDM-1, AIM-1) but tha

125 zinc centers of B1 (IMP-1; BcII) and B3 (L1) MBLs via the free thiol, but orient differently dependin

126 inding member of the metallo-beta-lactamase (MBL) fold superfamily.

127 d to the prokaryotic metallo-beta-lactamase (MBL) fold.

128 18, and 7 carried no metallo-beta-lactamase (MBL) gene.

129 Metallo-beta-lactamase (MBL) inhibitors can restore the function of carbapenem a

130 The metallo-beta-lactamase (MBL) is a candidate protein family that includes ribo- a

131 and global spread of metallo-beta-lactamase (MBL) mediated resistance, specifically New Delhi metallo

132 Members of the metallo-beta-lactamase (MBL) superfamily of enzymes harbor a highly conserved al

133 al susceptibility of metallo-beta-lactamase (MBL)-harboring Enterobacteriaceae We also evaluated the

134 carbapenemases and metallo-beta-lactamases (MBL).

135 Metallo-beta-lactamases (MBLs) degrade a broad spectrum of beta-lactam antibiotic

136 xamples are metal-dependent beta-lactamases (MBLs) from the marine organisms Novosphingobium pentarom

137 Metallo-beta-lactamases (MBLs) hydrolyze almost all beta-lactam antibiotics and a

138 biotics mediated by metallo-beta-lactamases (MBLs) is a growing problem.

139 ctamases (SBLs) and metallo-beta-lactamases (MBLs), especially those with carbapenemase activity, thr

140 linically important metallo-beta-lactamases (MBLs), including NDM-1 and VIM-1/2.

141 de dissemination of metallo-beta-lactamases (MBLs), mediating resistance to carbapenem antibiotics, i

142 e zinc-dependent or metallo-beta-lactamases (MBLs; class B).

143 al-dependent (i.e., metallo-beta-lactamases [MBLs]) carbapenemases when used in conjunction with the

144 idation of DMS in the marine boundary layer (MBL), via the hydrogen abstraction pathway, yields the s

145 t O3 reduction in the marine boundary layer (MBL).

146 ses functional human mannose-binding lectin (MBL) 2 under the control of Mbl1 promoter.

147 The collectins mannose-binding lectin (MBL) and surfactant protein D (SP-D) are regulated by ti

148 Collectins such as mannose-binding lectin (MBL) and surfactant protein D (SP-D) become temporarily

149 Measurement of mannan binding lectin (MBL) antigenic level and activity revealed MBL deficienc

150 e immune functions of mannan-binding lectin (MBL) associated protein (MAP) and MBL associated serine

151 rovide evidence that mannose-binding lectin (MBL) binds to beta2-GPI in Ca(++) and a dose-dependent m

152 e similar to C1q and mannose-binding lectin (MBL) participate in microbe infection and apoptotic cell

153 The mannose-binding lectin (MBL) pathway of the complement cascade has an essential

154 ecognition domain of mannose binding lectin (MBL) to target native HIV Env (CD4-MBL CAR).

155 d Bb, lectin pathway mannose-binding lectin (MBL), and shared neurotoxic effectors C3b and C5b-9 term

156 binding of the PRMs mannose-binding lectin (MBL), ficolin-1, ficolin-2, and ficolin-3, the associate

157 red that ligation of mannose-binding lectin (MBL), which binds to glycans of the fungal wall to activ

158 rum concentration of mannose-binding lectin (MBL), which exacerbates local inflammatory processes.

159 rs in a complement-, mannose-binding lectin (MBL)-, and immunogen glycan-dependent manner.

160 eered human opsonin--mannose-binding lectin (MBL)--that captures a broad range of pathogens and toxin

161 complement inhibitor, mannan-binding lectin (MBL)-associated protein (MAp)44, in regulating the compo

162 wn that mice lacking mannose-binding lectin (MBL)-associated serine protease-1 (MASP-1) and MASP-3 co

163 bits the function of Mannose Binding Lectin (MBL).

164 d inactivates C1 and mannose-binding lectin (MBL)/ficolins, important pattern- recognition receptors

165 Various recombinant mannose binding lectins (MBLs) and MBLs in sera of both murine and human origin b

166 s, and that flapless surgery results in less MBL compared with traditional open-flap surgery.

167 assess, with regard to marginal bone level (MBL), whether the outcome of immediate implant placement

168 linical parameters and marginal bone levels (MBLs) around tissue level implants with a partially smoo

169 Changes in marginal bone levels (MBLs) from Tb to T1 and from T1 to T2 were evaluated.

170 matic example is the many-body localization (MBL) transition, which marks the breakdown of thermaliza

171 Many-body localization (MBL), the disorder-induced localization of interacting p

172 robing, and radiographic marginal bone loss (MBL) >=3 mm.

173 loss (AL) were measured; marginal bone loss (MBL) around all teeth was measured on digital radiograph

174 luate survival rates and marginal bone loss (MBL) around implants placed in sites treated with maxill

175 ailure was influenced by marginal bone loss (MBL) at T1 and not surgical modality.

176 h (PD) were recorded and marginal bone loss (MBL) were assessed using standardized digital radiograph

177 al attachment loss (AL), marginal bone loss (MBL), and number of missing teeth, were recorded.

178 en shown to affect early marginal bone loss (MBL).

179 relating osteoporosis to marginal bone loss (MBL).

180 o 1.14 mm, P = 0.28) for marginal bone loss (MBL).

181 cations; 3) peri-implant marginal bone loss (MBL); 4) esthetic and periodontal parameters; and 5) pat

182 ttachment loss (AL), and marginal-bone-loss (MBL) were assessed.

183 ttachment loss [AL], and marginal bone loss [MBL]) and numbers of missing teeth (MT) were recorded.

184 ttachment loss [AL], and marginal bone loss [MBL]) were measured.

185 al attachment loss [AL], marginal bone loss [MBL], plaque index [PI], and bleeding on probing [BOP] i

186 Monoclonal B lymphocytosis (MBL) is defined as the presence of a clonal B-cell popul

187 LL (5.3%) and in monoclonal B lymphocytosis (MBL, 7%), a B-cell expansion that can evolve to CLL.

188 Monoclonal B-cell lymphocytosis (MBL) is a precursor lesion that can be screened for in a

189 Monoclonal B-cell lymphocytosis (MBL) is a precursor of chronic lymphocytic leukemia (CLL

190 A statistically higher mean MBL was found in the control group compared with the tes

191 demonstrated statistically significant mean MBL in the control group, but not in the test group.

192 Because beta2-GPI-mediated MBL-dependent thrombin generation was increased after pr

193 -9), the lectin pathway recognition molecule MBL, and antibody serology were analyzed by enzyme-immun

194 The Muscleblind (MBL) protein family is a deeply conserved family of RNA

195 The prevalence of CD5-negative MBL was higher in the Ugandan cohort (41 [14%], of whom

196 ukaemia (CLL)-phenotype MBL and CD5-negative MBL, as well as differences in absolute monoclonal B-cel

197 Nonetheless, MBL changes were similar in the test and control groups

198 is critical for the uptake of SP-D, but not MBL, indicating an additional level of complexity in the

199 CBA/J x DBA/2 combination in the absence of MBL-C and was undetectable in BALB/c-mated CBA/J mice.

200 complement cascade through the activation of MBL.

201 ccur on endothelial cells because binding of MBL to beta2-GPI was detected on the surface of HUVECs,

202 ent in human carotid plaques, and binding of MBL to CC was confirmed in vivo by immunohistochemistry,

203 The majority of cases of MBL have the immunophenotype of chronic lymphocytic leuk

204 prevalence and phenotypic characteristics of MBL in age-and-sex-matched populations from rural Uganda

205 the surface of HUVECs, and colocalization of MBL with beta2-GPI was observed on the endothelium of a

206 Meta-analysis for the comparison of MBL among selected studies showed a WMD of -0.80 mm (95%

207 al treatment reduced serum concentrations of MBL (1,099.35 +/- 916.59 to 861.42 +/- 724.82 ng/mL; P <

208 iated with decreased serum concentrations of MBL and CRP and increased serum levels of SIRT1.

209 was observed between serum concentrations of MBL and SIRT1 (r = -0.30; P = 0.006).

210 r oncogenic progression, whereas deletion of MBL or C3 in the extratumoral compartment-or knockdown o

211 BL host range is determined by the impact of MBL expression on bacterial fitness.

212 cal periodontal treatment on serum levels of MBL and SIRT1.

213 mmunohistochemistry, showing localization of MBL around CC clefts.

214 es and 83.4% of distal sites showed <1 mm of MBL, whereas 35.2% of mesial sites and 37% of distal sit

215 Observations of MBL in blood donors raise concern that transmitted MBL m

216 flow cytometry to determine the presence of MBL, defined according to standard diagnostic criteria,

217 To conclude, we show a protective role of MBL in the early stages of B. burgdorferi infection, yet

218 Here we set out to investigate the role of MBL in the immune response against B. burgdorferi in mor

219 e first ring-opening polymerization (ROP) of MBL, thereby producing exclusively unsaturated polyester

220 paves the way to further detailed studies of MBL, such as in noncorrelated disorder or higher dimensi

221 vestigated their ability, as well as that of MBL homologs from human/mouse, fly and worm, to regulate

222 drive the uPARAP-mediated cellular uptake of MBL and SP-D.

223 nalyze the weighted mean difference (WMD) of MBL between groups of thick and thin peri-implant soft t

224 ghlighting both the extraordinary ability of MBLs to adapt to changing environmental conditions and t

225 e successful dissemination and adaptation of MBLs to different bacterial hosts depend on protein dete

226 The extent of dissemination of MBLs such as VIM-2, SPM-1 and NDM among Gram-negative pa

227 cations for the mechanisms and inhibition of MBLs by beta-lactams and non-beta-lactams and illustrate

228 Clinically approved inhibitors of MBLs are currently unavailable as design has been limite

229 ons, especially regarding the interaction of MBLs with inhibitors.

230 In uncommon hosts, inefficient processing of MBLs leads to accumulation of toxic intermediates that c

231 BTZs therefore inhibit the full range of MBLs and potentiate beta-lactam activity against produce

232 The signal peptide sequence of MBLs dictates their adaptability to each host.

233 B. burgdorferi are significantly more often MBL deficient compared to humans without antibodies agai

234 The effect of several variables on MBLs changes was assessed via univariate and multivariat

235 erence in UWSFR, number of missing teeth, or MBL among habitual gutka chewers and controls.

236 discovered a function for LACTB2, an orphan MBL protein found in mammalian mitochondria.

237 e screening approach can be adapted to other MBLs and in this way improve the drug discovery process

238 Overall MBL prevalence was higher in the Ugandan participants (4

239 pes of polymers, P(MBL)VAP, P(MBL)CLP, and P(MBL)ROP, can be readily controlled by adjusting the cata

240 roducing exclusively unsaturated polyester P(MBL)ROP with Mn up to 21.0 kg/mol.

241 esses, thus affording cross-linked polymer P(MBL)CLP.

242 formation of the three types of polymers, P(MBL)VAP, P(MBL)CLP, and P(MBL)ROP, can be readily contro

243 inyl-addition polymerization (VAP) product P(MBL)VAP.

244 The resulting P(MBL)ROP is degradable and can be readily postfunctionali

245 of the three types of polymers, P(MBL)VAP, P(MBL)CLP, and P(MBL)ROP, can be readily controlled by adj

246 NMR) to study the dynamics of the Sao Paulo MBL (SPM-1) from beta-lactam-resistant Pseudomonas aerug

247 hronic lymphocytic leukaemia (CLL)-phenotype MBL and CD5-negative MBL, as well as differences in abso

248 CLL-phenotype MBL was detected in three (1%) Ugandan participants and

249 4%], of whom two [5%] also had CLL-phenotype MBL) than in the UK cohort (six [2%], of whom two [33%]

250 %], of whom two [33%] also had CLL-phenotype MBL; p<0.0001), but the median absolute B-cell count was

251 One year after definitive crown placement, MBL loss was 0.56 +/- 0.39 mm mesially and 0.74 +/- 0.51

252 -rich conditions are typical of the polluted MBL, near coastlines and ship plumes.

253 and RIS on O3 mixing ratios in the polluted MBL.

254 ood starting points for the design of potent MBL inhibitors.

255 susceptibility of Escherichia coli-producing MBLs (IMP-1, Sfh-1, BcII, and GOB-18) and, significantly

256 g lectin-mannose-associated serine protease (MBL-MASP) functional activity in Crohn's disease patient

257 We identified putative MBL homologs in Ciona intestinalis and Trichoplax adhaer

258 i-implant soft tissue have less radiographic MBL in the short term.

259 y clinical parameter or for the radiographic MBL.

260 similar clinical parameters and radiographic MBLs as those in thick tissue.

261 lement activation via its ability to recruit MBL to MASP, and other hand as a modulator of immune cel

262 fragments inhibiting the clinically relevant MBL Verona integron-encoded metallo-beta-lactamase (VIM-

263 In the remote MBL, unimolecular isomerization of MSP outpaces bimolecu

264 (MBL) antigenic level and activity revealed MBL deficiency.

265 erved binding of the bicyclic core with SBLs/MBLs.

266 ll be useful in the development of selective MBL inhibitors.

267 inant CsMAP34 (rCsMAP34) bound C. semilaevis MBL (rCsBML) when the latter was activated by bacteria,

268 Serum MBL concentrations < 787 and < 445 ng/ml were associated

269 First, we determined a serum MBL concentration cut-off level associated with diminish

270 rchives of our laboratory and measured serum MBL concentrations in both sample groups.

271 Also, the age-adjusted median serum MBL concentrations were significantly lower in the LB pa

272 thway function, represented by reduced serum MBL concentration, predisposes individuals to LB.

273 rience over more than 30 years indicate that MBL/CLL transmission does not contribute importantly to

274 Here, we report that MBL host range is determined by the impact of MBL expres

275 The results showed that MBL had attractive colour, exhibited higher anthocyanin

276 We showed that MBL is capable of binding B. burgdorferi through its car

277 The MBL research training courses Neurobiology and Neural Sy

278 we observe quantum critical behaviour at the MBL transition in a disordered Bose-Hubbard system and c

279 asirandom optical lattice and identified the MBL transition through the relaxation dynamics of an ini

280 a suggests that the lifetime of HPMTF in the MBL at this sampling location is likely controlled by he

281 r findings indicate that a deficiency in the MBL pathway of the complement cascade is a risk factor f

282 ure revealed almost perfect alignment of the MBL domain with CPSF73, as well as to other ribonuclease

283 ds is an indicator of proper function of the MBL pathway.

284 73, as well as to other ribonucleases of the MBL superfamily.

285 gations demonstrating the versatility of the MBL-fold domain in supporting a variety of enzymatic rea

286 Optimization of the MBL-GS muPADs was carried out for direct determination o

287 Proof of concept of the MBL-GS muPADs was demonstrated by analyzing standard sol

288 ant differences appear to relate only to the MBL with the placement of implants in regenerated bone s

289 enemases, specifically the SBL KPC-2 and the MBLs NDM-1 and VIM-2.

290 Therefore, MBL can be an acceptable new liquor, with better quality

291 mated CBA/J mice with Polyman2 that binds to MBL-A with high affinity proved to be highly effective i

292 nt harbored the LXA/LYC haplotypes linked to MBL deficiency.

293 Binding of NS1 to MBL protects DENV against mannose-binding lectin-mediate

294 blood donors raise concern that transmitted MBL may cause recipient CLL.

295 While both proteins contain a typical MBL-beta-CASP domain, a region of positive charge surrou

296 ress and strategies toward clinically useful MBL inhibitors.

297 riment did not reveal the mechanism by which MBL facilitates early clearance of B. burgdorferi.

298 and coding region variations associated with MBL deficiency and the same complement pattern in immune

299 ants in regenerated bone are correlated with MBL and MCI.

300 gement, and supportive care of patients with MBL and CLL.