ライフサイエンスコーパス: MBP

1 MBP adsorbs on normal bilayers to form a compact film (3

2 MBP conjugated fluorescent dye-encapsulating liposomes s

3 MBP is an abundant myelin protein involved in demyelinat

4 MBP preferentially adsorbs to liquid-disordered submicro

5 MBP showed no significant benefit to infectious complica

6 MBP then folds to the native state on a longer time scal

7 MBP with or without antibiotics was associated with redu

8 MBP with oral antibiotics reduces by nearly half, SSI, a

9 MBP(84-104) acts through sustained co-activation of meta

10 MBP+/ABX+ was also associated with lower anastomotic lea

11 MBP-1 immune serum significantly inhibited M. avium subs

12 MBP-mediated assembling of lipid bilayers proceeds in tw

13 MBPs thus play a key intermediary role in gene regulatio

14 MBPs, including the thermostable PfuMBP, have been demon

15 reparation type: 14.9% no preparation, 12.0% MBP, and 6.5% OABP (P < 0.001).

16 e encoding microaggregate-binding protein 1 (MBP-1) (MAV_3013) is highly expressed during microaggreg

17 ranules (by mass) are major basic protein 1 (MBP-1) and eosinophil peroxidase (EPX).

18 Gelatin-MBP and gelatin-TiO(2)-MBP electrodes were prepared by chemical immobilization

19 ween Anti-MBP and gelatin-MBP/gelatin-TiO(2)-MBP immunosensor is quasireversible.

20 ansfer reaction occurs on the gelatin-TiO(2)-MBP immunosensor surface.

21 for gelatin-MBP and 46 s for gelatin-TiO(2)-MBP immunosensor).

22 Gelatin-MBP and gelatin-TiO(2)-MBP immunosensors have detection limit of 0.1528 ng ml(-

23 P confined on gelatin-MBP and gelatin-TiO(2)-MBP surfaces are estimated to be 195 and 205 mV, respect

24 ents, 2296 (27.2%) had no-prep, 3822 (45.3%) MBP+/ABX-, and 2324 (27.5%) MBP+/ABX+.

25 SI [MBP+/ABX+: OR = 0.39, 95% CI: 0.32-0.48; MBP+/ABX-: OR = 0.80, 95% CI: 0.69-0.93] versus no-prep.

26 ep, 3822 (45.3%) MBP+/ABX-, and 2324 (27.5%) MBP+/ABX+.

27 57, 95% confidence interval (CI): 0.48-0.68; MBP+/ABX-: OR = 0.78, 95% CI: 0.68-0.91] and SSI [MBP+/A

28 g resources to rapidly characterize abundant MBP proteoforms within murine tissue.

29 reoperative MBP and antibiotics (MBP+/ABX+), MBP alone (MBP+/ABX-), and no bowel preparation (no-prep

30 Following eosinophil activation, MBP-1 toxicity is triggered by granule acidification, fo

31 This co-occurred with active MBP-positive granule release and the expression of integ

32 In addition, MBP dimers form a correlated mesh-like network within th

33 sis for future rational design of additional MBP-harboring drugs targeting hGGPPS.

34 MBP and antibiotics (MBP+/ABX+), MBP alone (MBP+/ABX-), and no bowel preparation (no-prep) on outcom

35 n 60 residues were not inserted; however, an MBP-2Pf3-Lep fusion protein could be ranslocated.

36 ype cerebellar neurons in the presence of an MBP antibody or L1 peptide containing the MBP cleavage s

37 On multivariable analysis, MBP with antibiotics, but not without, was independently

38 to simultaneously knock down kinesin-13 and MBP, we created a stable dual knockdown strain with both

39 Binding scores with SA-CAP-2 and MBP-CAP-1 to MBP-CAP-4 were generally lower but strongly

40 primary sites for ERE activation by BPA and MBP, and transcriptomic analysis of microdissected heart

41 vels correlated negatively with SBP, DBP and MBP values in all participants (p = 0.0010; p = 0.0350 a

42 GSSG correlated positively with SBP, DBP and MBP values in all participants (p = 0.0410; p = 0.0330 a

43 Thermodynamic analysis of numerous GA and MBP variants suggests that the key to our approach invol

44 creased expression levels of both Krox20 and MBP in SC-motor neuron (MN) coculture, which was notably

45 ation of myelin basic protein (Mbp) mRNA and MBP protein to the cellular processes where it is necess

46 ampus, whereas reductions in CD200, NGF, and MBP were evident.

47 hat there may be a role for combined OAB and MBP, or OAB alone in the prevention of surgical site inf

48 preparation: none, MBP only, OABP only, and MBP plus OABP adjusting for other covariates.

49 by targeting cytoskeletal reorganization and MBP localization to oligodendrocyte processes.SIGNIFICAN

50 outcome and performed better than S100B and MBP.

51 two well-studied blood biomarkers, S100B and MBP.

52 the interactions between the transporter and MBP in nanodiscs and in detergent.

53 cate that the electron transfer between Anti-MBP and gelatin-MBP/gelatin-TiO(2)-MBP immunosensor is q

54 ethod for the specific determination of Anti-MBP in human cerebrospinal fluid (CSF) and serum samples

55 The newly developed GO/pPG/anti-MBP/anti-Tau nanoimmunosensor has been established by im

56 utoantibody, Anti-Myelin Basic Protein (Anti-MBP) was developed by immobilization of MBP on Gelatin a

57 Using anti-MBP-1 immune serum, microaggregate binding to HEp-2 cell

58 impact of preoperative MBP and antibiotics (MBP+/ABX+), MBP alone (MBP+/ABX-), and no bowel preparat

59 and treatment with atypical antipsychotics, MBP and lamotrigine, and H-FABP and lithium.

60 We report here that an Arabidopsis MBP-1-like protein (AtMBP-1) is alternatively translated

61 ocal microscopy, microaggregates, as well as MBP-1, induced vimentin polymerization at the site of ba

62 ity pull-down assay, the interaction between MBP-5HT(3A)-ICD constructs and RIC-3 was investigated.

63 chlorinated methyl- and dimethyl bipyrroles (MBPs and DMBPs) were the most abundant natural products.

64 emi-open MalK2 conformation by maltose-bound MBP is key to the coupling of maltose transport to ATP h

65 Maltose-bound MBP promotes the transition to the semi-open state of Ma

66 ll engagement of both lobes of maltose-bound MBP unto MalFGK2 is facilitated by nucleotides and stabi

67 higher gestational exposure to mono-n-butyl (MBP) and mono-3-carboxypropyl (MCPP) concentrations exhi

68 icrometer-sized domains that were induced by MBP in live epithelial PtK2 cells.

69 female-specific hypersensitivity induced by MBP(84-104).

70 ns of VPS34, VPS15, and BECN1 were mapped by MBP tagging.

71 o North American marine mammals, chlorinated MBPs and DMBPs were more abundant than their brominated

72 0), and mature oligodendrocyte markers (CNP, MBP) were quantified.

73 Combined MBP plus OABP before elective colectomy was associated w

74 Combined MBP/ABP results in significantly lower rates of SSI, org

75 available on the comparison between combined MBP+OAB versus no preparation, OAB alone versus no prepa

76 fferentiate between the benefits of combined MBP+OAB or OAB alone.

77 rystal structures of the transporter complex MBP-MalFGK2 bound with large malto-oligosaccharide in tw

78 hwann cell cocultures dramatically decreased MBP and P0 levels and myelin sheath formation without af

79 mRNA distribution and dramatically decreases MBP protein levels.

80 yl-5-oxohexyl) phthalate, MECPP, Sigma DEHP, MBP, and mono-(3-carboxypropyl) phthalate metabolite lev

81 of this interaction, we developed different MBP-fused 5-HT(3A)-ICD constructs by deleting large segm

82 Knockdown of the ventral disk MBP protein also causes severe structural defects that a

83 tides in a mutually exclusive manner (either MBP or TCR-derived, but not both) suggest that there is

84 ression is reduced in PPMS; this exacerbates MBP-specific inflammatory T cell response and reduces th

85 seen to have detection limits of 0.30nM for MBP and 0.15nM for Tau proteins which were sufficient fo

86 e largest effect estimates were observed for MBP and MiBP (49-50% increase in 8-isoprostane with an i

87 ormation of membrane stacks all the way from MBP binding onto a single membrane leaflet to the organi

88 Gelatin-MBP and gelatin-TiO(2)-MBP electrodes were prepared by c

89 Gelatin-MBP and gelatin-TiO(2)-MBP immunosensors have detection

90 ectron transfer between Anti-MBP and gelatin-MBP/gelatin-TiO(2)-MBP immunosensor is quasireversible.

91 ity and low response times (58 s for gelatin-MBP and 46 s for gelatin-TiO(2)-MBP immunosensor).

92 formal potentials of MBP confined on gelatin-MBP and gelatin-TiO(2)-MBP surfaces are estimated to be

93 Because of the high MBP, the delay was increased to 30 h in C2, increasing T

94 , resulting in high T-SUVmax but with higher MBP than in C2.

95 ulosis (MtUGM) was obtained from a dual His6-MBP-tagged MtUGM construct.

96 How MBP-1 toxicity is controlled within the eosinophil itsel

97 Yet, it is not clear how MBP influences the organization and dynamics of the lipi

98 ion for behavior in suicide completers (IL6, MBP, JUN, KLHDC3) steps in a completely independent test

99 tibiotics was associated with reduced ileus [MBP+/ABX+: odds ratio (OR) = 0.57, 95% confidence interv

100 ls but not immature oligodendrocytes impeded MBP mRNA transcription, thereby preventing MBP protein s

101 Activating apoptosis in MBP(+) cells of the developing spinal cord during the fi

102 A doubling in MBP or MCPP concentrations was associated with 0.6 (95%

103 ric oxide (NO) and the expression of iNOS in MBP-primed splenocytes.

104 tgrowth and neuronal survival are reduced in MBP-deficient cerebellar neurons and in wild-type cerebe

105 enesis of the proteolytically active site in MBP or of the MBP cleavage site within L1 as well as ser

106 ber of mature oligodendrocytes and increases MBP, leading to remyelination and functional recovery of

107 lows for the selective cleavage of MBP3 into MBP and MBP2.

108 Here we show how intragranular MBP-1 nanocrystals restrain toxicity, enabling its safe

109 haracterization workflow resolved four known MBP ASVs and hundreds of differentially modified states

110 e confirmed by histopathology for high-level MBP exposure, and structural defects (abnormal curvature

111 s, with reduced myelin basic protein levels (MBP) compared to levels in the C57Bl/6 mouse.

112 anes with modified lipid composition and low MBP concentration, as in demyelinating disease, show str

113 Like mammalian MBP-1, this truncated form of LOS2 has little, if any, e

114 ssion and differentiation of OPC into mature MBP-expressing oligodendrocytes.

115 nonallergenic maltose-binding protein (MBP; MBP-CAP-1 to 4) and binding to a panel of 4 recombinant

116 reatinine- normalized concentrations of MEP, MBP, MEOHP, MEHHP, SigmaLMWP and SigmaHMWP.

117 equivalent concentrations of its metabolite MBP, using fluorescent reporter embryo-larval zebrafish,

118 he heart valves by BPA's reactive metabolite MBP and the development of valvular-cardiovascular disea

119 (MBH) carbonates with 2-methylbenzophenone (MBP) derivatives as nonstabilized photogenerated C-nucle

120 r approach involved stabilizing the modified MBP and OspA subdomains via external interactions with n

121 pearance of multi-branched 'pre-myelinating' MBP+ / PLP+ oligodendrocytes that interact with axons bu

122 d effector CD8(+) T cells ex vivo, and naive MBP-specific CD8(+) T cells were activated in the CNS du

123 Here, we investigated whether naive MBP-specific CD8+ T cells recruited to the CNS during CD

124 markers SOX10, KROX20 (EGR2), p75NTR (NGFR), MBP and S100B by day 4 in virtually all cells, and matur

125 ased on the type of bowel preparation: none, MBP only, OABP only, and MBP plus OABP adjusting for oth

126 f the expression of signatory genes of O1(+)/MBP(+) OLs and their cellular populations.

127 Furthermore, we observe MBP to insert into its bilayer leaflet side in case of t

128 Genetic ablation of MBP in shiverer mice and mutagenesis of the proteolytica

129 Moreover, the absence of MBP-1 and EPX promoted a concomitant loss of eosinophil

130 Administration of MBP/OABP before elective colectomy reduces the incidence

131 T cell response and reduces the apoptosis of MBP-specific T lymphocytes, possibly as a consequence of

132 The association of MBP with lipid membranes has been studied for decades, b

133 Cleavage resulted in covalent attachment of MBP-VirD2 to the 5'-cleaved end, consistent with convent

134 e that the initiation of the biosynthesis of MBP mRNA relies on a syntaxin 4-dependent mechanism, whi

135 odendrocytes was able to rescue the block of MBP mRNA transcription in syntaxin 4-downregulated cells

136 The combination of MBP+OAB versus MBP alone was associated with a significa

137 When a combination of MBP+OAB was compared with OAB alone, no significant diff

138 ssue damage under pathological conditions of MBP-1 oversecretion.

139 ole for ERK2 in the translational control of MBP, a myelin protein that appears critical for ensuring

140 expression constructs for crystallization of MBP fusion proteins remains a challenge.

141 nstabilities and enhanced local curvature of MBP-lipid multilayer structures.

142 air was reflected in decreased expression of MBP and proteolipid protein and a reduction in the total

143 IRAK1 and TRAF6 and decreased expression of MBP.

144 membrane bilayers, only the liganded form of MBP efficiently stimulates its activity.

145 ings provide evidence for novel functions of MBP in the nervous system.

146 Enzymatic deimination prevents hydrolysis of MBP by the proteasome, suggesting that an abnormally bas

147 or has been established by immobilization of MBP and Tau antibodies.

148 Anti-MBP) was developed by immobilization of MBP on Gelatin and Gelatin-Titanium Dioxide (TiO(2)) mod

149 Infiltration of MBP-specific CD8+ T cells enhanced ROS production in the

150 otein (Mbp) gene with an accelerated loss of MBP that correlates with a lack of myelin sheath formati

151 t differences in the adsorption mechanism of MBP.

152 ed OL maturation by increasing the number of MBP(+) cells significantly (p<0.01).

153 e formation of an amorphous protein phase of MBP between two membrane bilayers and provide a molecula

154 The formal potentials of MBP confined on gelatin-MBP and gelatin-TiO(2)-MBP surfa

155 The practice of MBP alone should be abandoned.

156 To increase the success rate of MBP-facilitated crystallization, a series of expression

157 y, which limits understanding of the role of MBP microheterogeneity in human physiology and disease.

158 The peak separations of MBP (150 mV and 110 mV s(-1) at 100 mV s(-1)) and the as

159 e known separation of the N and C termini of MBP than FRET.

160 SSI is on causal pathway between the use of MBP/OABP and the reduction of other postoperative compli

161 The affinity of MBPs is dependent on a large number of factors including

162 e variety of forces governing the binding of MBPs to active site metal ions.

163 ed members of the zinc finger (ZF) family of MBPs in propagating DNA methylation signals into downstr

164 n basic protein expressing oligodendrocytes (MBP-iCP9).

165 Moreover, the region on MBP responsible for this activity was localized to the 6

166 rgeting ligand myeloid cell-binding peptide (MBP) incorporated in the capsid displayed a reduced lung

167 ) ion docking, and MD simulations of peptide-MBP chimeras corroborated the extent of Cu(2+) binding a

168 Most of these peptide-MBP chimeras conferred tolerance to high concentrations

169 ected the presence of eosinophil peroxidase, MBP, and fibrin alpha-, beta-, and gamma-chains.

170 entified from a metal-binding pharmacophore (MBP) library screen.

171 ug design with metal-binding pharmacophores (MBP).

172 of a series of metal-binding pharmacophores (MBPs) related to the ligand 1-hydroxypyridine-2-(1H)-thi

173 f a library of metal-binding pharmacophores (MBPs) revealed that 8-thioquinoline (8TQ, IC50 value app

174 represented by metal-binding pharmacophores (MBPs), metalloenzyme structural similarity (MeSIM) and l

175 tabolites as well as mono-n-butyl phthalate (MBP) and monoiso-butyl phthalate (MiBP).

176 yl phthalate (MBzP), mono-n-butyl phthalate (MBP), and monoisobutyl phthalate (MiBP), compared with d

177 yl phthalate (MiBP), mono-n-butyl phthalate (MBP), monobenzyl phthalate (MBzP), monoethyl phthalate (

178 (MECPP), as well as mono-n-butyl phthalate (MBP), were significantly higher in cases compared with c

179 oethyl phthalate (MEP), monobutyl phthalate (MBP), monobenzyl phthalate (MBzP), mono (2-ethylhexyl) p

180 Despite robust developmental plasticity, MBP-iCP9-induced oligodendrocyte apoptosis compromised t

181 G activity below the mediastinal blood pool (MBP) uptake.

182 max) and T-SUVmax-to-mediastinum blood-pool (MBP) SUVmean ratios (T/MBP) were determined.

183 erentiated to myelin basic protein-positive (MBP(+)) oligodendrocytes.

184 rectal resection, the impact of preoperative MBP and antibiotics (MBP+/ABX+), MBP alone (MBP+/ABX-),

185 taneous use of mechanical bowel preparation (MBP) is unclear.

186 ion, 44.9% had mechanical bowel preparation (MBP) only, and 29.5% received OABP.

187 d MBP mRNA transcription, thereby preventing MBP protein synthesis.

188 tionally active 84-104 myelin basic protein (MBP(84-104)) fragment released after nerve injury, we de

189 phils were labeled with major basic protein (MBP) Ab to visualize granules and assessed by flow cytom

190 Myelin basic protein (MBP) and its interaction with lipids of the myelin sheat

191 postnatal myelination, myelin basic protein (MBP) and myelin-associated glycoprotein (MAG) myelin pro

192 eous quantification of Myelin Basic Protein (MBP) and Tau proteins in cerebrospinal fluid (CSF) and s

193 sed on the autoantigen myelin basic protein (MBP) and the MBP-derived peptide MBP85-99 presented to t

194 tocortex, and requires myelin basic protein (MBP) as its major structural component.

195 Here we show that myelin basic protein (MBP) binds to L1 in a Lewis(x)-dependent manner.

196 ed an amplification of myelin basic protein (MBP) expression and differentiation of OPC into mature M

197 sensitive impedimetric Myelin Basic Protein (MBP) immunosensor for the determination of a Multiple Sc

198 ion of both Krox20 and myelin basic protein (MBP) in SC culture medium containing dBcAMP/NRG1, which

199 -restricted epitope of myelin basic protein (MBP) is presented in the CNS during CD4+ T cell-initiate

200 and concentrations of myelin basic protein (MBP) on the structure of model lipid bilayers, as well a

201 (TCR) specific for the Myelin Basic Protein (MBP) peptide Ac1-9, making the animals susceptible to ex

202 , mostly occupied by a myelin basic protein (MBP) phase.

203 Myelin basic protein (MBP) plays an important structural and functional role i

204 MHC class I-restricted myelin basic protein (MBP) was presented by oligodendrocytes and cross-present

205 igodendrocytes forming myelin basic protein (MBP)(+) and proteolipid protein-positive myelin was impa

206 e mediators, eosinophil major basic protein (MBP), a hallmark of allergy, is particularly important b

207 that the expression of myelin basic protein (MBP), a myelin-specific protein that is synthesized "on

208 ltiple sclerosis (MS), myelin basic protein (MBP), critical for the maintenance of myelin compaction

209 component of myelin is myelin basic protein (MBP), expression of which requires anterograde mRNA tran

210 yered membrane sheath, myelin basic protein (MBP), is hydrolyzed by the 26S proteasome in a ubiquitin

211 nt light chain (NF-L), myelin basic protein (MBP), S100B, and heart-type fatty acid binding protein (

212 CEACAM-1 expression on myelin basic protein (MBP)-stimulated CD4(+) and CD8(+) T lymphocytes of 56 MS

213 (GFAP, p = 0.0074) and myelin basic protein (MBP, p = 0.0039) after FUS sonication as compared with b

214 ncluding the eosinophil major basic protein (MBP-1).

215 A periplasmic maltose-binding protein (MBP) delivers maltose to the transmembrane subunits (Mal

216 HT(3A)-ICD fused to maltose-binding protein (MBP) directly interacts with RIC-3, without the involvem

217 osensor, comprising maltose binding protein (MBP) flanked by a green fluorescent protein (GFP(2)) at

218 tructed, comprising maltose binding protein (MBP) flanked by a green fluorescent protein (GFP(2)) at

219 Even though the maltose-binding protein (MBP) is one of the most commonly used crystallization ch

220 SF-Fc) and with the maltose binding protein (MBP) tag at the N-terminus and expressed it as a soluble

221 these measurements, maltose binding protein (MBP) was isotopically labeled with (13)C and (15)N, perm

222 e proteins, pepsin, maltose binding protein (MBP), and carbonic anhydrase (CA) in the presence of hun

223 : calmodulin (CaM), maltose-binding protein (MBP), and dihydrofolate reductase (DHFR).

224 -transferase (GST), maltose-binding protein (MBP), N-utilisation substance protein A (NusA), human pr

225 of sugar binding to maltose-binding protein (MBP), the periplasmic binding protein, does not fully ac

226 unrelated bacterial maltose-binding protein (MBP), which yielded hormone production with an efficienc

227 ystal structures of maltose binding protein (MBP)-fused AID alone and in complex with deoxycytidine m

228 between R2TP and a Maltose Binding Protein (MBP)-fused Nop58p by biophysical and yeast genetics meth

229 motif and fused to Maltose Binding Protein (MBP).

230 ne subdomain within maltose binding protein (MBP, alpha/beta/alpha-sandwich) and another within outer

231 The tumor suppressor c-myc binding protein (MBP-1), which is alternatively translated from the secon

232 2) or nonallergenic maltose-binding protein (MBP; MBP-CAP-1 to 4) and binding to a panel of 4 recombi

233 ophil granule proteins (major basic protein [MBP] and eosinophil-derived neurotoxin [EDN]; Spearman's

234 the adhesive protein (myelin basic protein, MBP) composition.

235 malarial antigen-containing fusion protein, MBP-pfMSP1(19), in Escherichia coli, which then was stru

236 the translation of the major myelin protein, MBP.

237 Methyl-CpG binding proteins (MBPs) are specialized transcription factors that read an

238 protein fusion with Plasmodium knowlesi PSD (MBP-His6-Delta34PkPSD) as the enzyme.

239 eceived OABP only, and 5965 (30.3%) received MBP plus OABP.

240 eived no preparation, 7617 (32.67%) received MBP only, 1374 (5.89%) received ABP only, and 8855 (37.9

241 of bowel preparation, 8020 (40.7%) received MBP only, 641 (3.3%) received OABP only, and 5965 (30.3%

242 Patients who received MBP plus OABP had a lower incidence of superficial SSI,

243 d cells presented the MHC class I-restricted MBP ligand in the brain compared with the spinal cord.

244 Here, we demonstrate that the same MBP biosensor can be combined with a microfluidic system

245 Mechanistically, intra-sciatic MBP(84-104) induced phospholipase C (PLC)-driven (female

246 ssed in noninvasive Mycobacterium smegmatis, MBP-1 increased the ability of the bacteria to bind to H

247 ABX-: OR = 0.78, 95% CI: 0.68-0.91] and SSI [MBP+/ABX+: OR = 0.39, 95% CI: 0.32-0.48; MBP+/ABX-: OR =

248 As a proteasomal substrate, MBP reveals a distinct and physiologically relevant conc

249 In C1, T-SUVmax and T/MBP ranged from 4.09 to 8.93 and 1.39 to 3.72 at 60 min

250 delay to 42 h in C3 decreased T-SUVmax and T/MBP, showing that 30 h was the most favorable delay.

251 sed to 30 h in C2, increasing T-SUVmax and T/MBP.

252 diastinum blood-pool (MBP) SUVmean ratios (T/MBP) were determined.

253 single point mutation in the BRET(2) tagged MBP protein.

254 Unlike many other tags that were tested, MBP significantly enhanced the solubility of the protein

255 Patients with residual uptake higher than MBP uptake but below liver uptake had equally good outco

256 s (53%), the residual uptake was higher than MBP uptake but below the liver uptake in 27 (23%), sligh

257 Furthermore, we demonstrate that MBP is released by murine cerebellar neurons as a sumoyl

258 Meta-analyses have demonstrated that MBP does not impact upon postoperative morbidity or mort

259 ive and diseased lipid mixtures we find that MBP forms dense liquid phases on top of the lipid membra

260 re consistent with our previous finding that MBP(84-104)-induced pain is T cell-dependent.

261 d by coimmunoprecipitation, we observed that MBP-1 interacts with the host cytoskeletal protein vimen

262 Our data show that MBP reorganizes lipid diffusion, possibly by preventing

263 Our results suggest that MBP-1 aggregation is important for innate immunity and i

264 Despite recent literature suggesting that MBP does not reduce infection rate, it still is commonly

265 th an antivimentin antibody, suggesting that MBP-1 expression is important for M. avium subsp. homini

266 toantigen myelin basic protein (MBP) and the MBP-derived peptide MBP85-99 presented to the MS-associa

267 branes has been studied for decades, but the MBP-driven formation of the MDL remains elusive at the b

268 inhibitors and an L1 peptide containing the MBP cleavage site abolish generation of the L1 fragment.

269 an MBP antibody or L1 peptide containing the MBP cleavage site.

270 raries of molecules were elaborated from the MBP hits.

271 Furthermore, the MBP variant (80% identical to GA) remained active.

272 composed of segments that are distant in the MBP sequence but adjacent in the native protein where th

273 lous both in oligodendrocytes and inside the MBP-rich domains of PtK2 cells compared with undisturbed

274 proteolytically active site in MBP or of the MBP cleavage site within L1 as well as serine protease i

275 ive transcriptional start site (ATSS) of the MBP gene as well as a never before characterized S-acyla

276 Upon differentiation, mRNA levels of the MBP gene, encoding myelin basic protein, were significan

277 slower step (7-s time constant), all of the MBP molecules, although initially heterogeneously struct

278 st to myelin sheets in oligodendrocytes, the MBP-induced domains in epithelial PtK2 cells demonstrate

279 pitopes (ITEM-THREE), to map the area on the MBP-pfMSP1(19) antigen surface that is recognized by the

280 an assembled (conformational) epitope on the MBP-pfMSP1(19) antigen whose identification was substant

281 We found that the MBP-specific CD8+ T cells exacerbated brain but not spin

282 Thus, the MBP tag is useful for efficient prokaryotic production a

283 Thus, the MBP-hFGF21 construct was further pursued for optimisatio

284 n only in these cell types and only when the MBP-specific CD8+ T cells expressed Fas ligand (FasL).

285 This MBP-stimulated ATPase activity is independent of maltose

286 ng protein upon L1 stimulation and that this MBP cleaves L1 as a serine protease in the L1 extracellu

287 inding scores with SA-CAP-2 and MBP-CAP-1 to MBP-CAP-4 were generally lower but strongly correlated w

288 lFGK2 despite their high binding affinity to MBP.

289 monstrate that exposing the sciatic nerve to MBP(84-104) via endoneurial injection produces robust me

290 Translated MBP exhibits extreme microheterogeneity with numerous al

291 monodentate, 191 bidentate and 15 tridentate MBP chemotypes were included in MeLAD, which are linked

292 The combination of MBP+OAB versus MBP alone was associated with a significant reduction in

293 alone versus no preparation, and OAB versus MBP.

294 ; p = 0.0350 and p = 0.0050) as well as with MBP values in high normal and grade 1 hypertension (p =

295 r and distal to the lesion, colocalized with MBP, and abutted Caspr+ profiles, suggesting newly forme

296 OAB preparation, either in combination with MBP or alone, in the prevention of postoperative complic

297 ibiotics can therefore be considered without MBP for patients who undergo colorectal surgery.

298 ectal surgery, receiving OAB with or without MBP was performed.

299 in SSI and/or mortality in a setting without MBP.

300 med toward expanding our understanding of ZF MBP cellular roles will provide needed mechanistic insig