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1 MPA (P < .005) and dexamethasone (P < .01), but not NET-
2 MPA affected intracellular nucleotide levels, nucleotide
3 MPA clearance was higher than in women with HIV not on A
4 MPA clearance was higher than in women with HIV not on A
5 MPA exposure increased intracellular concentrations of f
6 MPA PK parameters were calculated using non-compartmenta
7 MPA PK parameters were calculated using noncompartmental
8 MPA significantly altered 35 proteins mainly related to
9 MPA treatment interferes with transcription elongation,
10 MPA treatment of Huh7 cells could suppress autophagy, ev
11 MPA treatment of infected mice resulted in 50% mortality
12 MPA was associated with inhibited cell proliferation and
13 MPA was computed as 200 cGy/DTotal for each DTotal estim
14 MPA, but not NET-A, subverts mycobacterial containment i
18 gement and fish population data (433 and 218 MPAs, respectively) to assess: MPA management processes;
21 3-MPA inhibited PEPCK-M enzyme activity as 3-MPA interfered with the PEPCK enzyme assay, particularly
22 iation was significantly induced following 3-MPA treatment (0.25, 0.5, 1 mM) from day 0 of differenti
25 However, we were unable to confirm that 3-MPA inhibited PEPCK-M enzyme activity as 3-MPA interfere
26 isoform in C2C12 cells, we postulate that 3-MPA promoted myogenic differentiation through the inhibi
27 MPO- or PR3-ANCA-positive patients with AAV (MPA and GPA) and severe kidney disease (eGFR <30 ml/min
28 25 mg/day) plus medroxyprogesterone acetate (MPA) (<10 mg/day) or oral CEE alone and cardiovascular d
29 /- 10(-7) mol/L medroxyprogesterone acetate (MPA) +/- 1 IU/mL thrombin pretreatment for 4 hours, wash
30 estrogens plus medroxyprogesterone acetate (MPA) among participants with an intact uterus were carri
33 contraceptives, medroxyprogesterone acetate (MPA) and norethisterone acetate (NET-A), on host suscept
35 at clearance of medroxyprogesterone acetate (MPA) would increase when given with rifampicin and efavi
37 ith TFV or TAF, Medroxyprogesterone acetate (MPA), but not Levonorgestrel, Norethisterone or progeste
38 .625 mg/d) plus medroxyprogesterone acetate (MPA, 2.5 mg/d) (n = 8506) vs placebo (n = 8102) for 5.6
41 rochloride (Cyst), 3-Mercaptopropionic acid (MPA), 11-Mercaptoundecanoic acid (MUDA) and 11-amino-1-u
42 d with the help of 3-mercaptopropionic acid (MPA)-capped CdSe quantum dot (MPA-CdSe QD) and visible l
43 d from day 5 according to mycophenolic acid (MPA) exposure (arm A) or a regimen with CS maintained up
48 ("one-dose-fits-all"), to mycophenolic acid (MPA) trough concentration monitoring, to dose optimizati
49 teroids and alternatively Mycophenolic Acid (MPA, n=38) or mTORi (either everolimus or sirolimus, n=3
50 teroids and alternatively mycophenolic acid (MPA; n = 38), or mTORi (either everolimus or sirolimus,
51 r (S)-alpha-methoxy-alpha-phenylacetic acid (MPA) or (S)-phenylglycine methyl ester (PGME) linked thr
52 osphonate (DMMP) and methyl phosphonic acid (MPA) exhibit the reduced mobility values of 1.99 +/- 0.0
53 nolate mofetil [MMF], and mycophenolic acid [MPA]), but not obatoclax or Osu-03012, showed potent ant
55 radiation, the maximum permissible activity (MPA) of (131)I to treat thyroid cancer is that which lim
59 networks of MPAs operate if the space among MPAs is smaller than the dispersal capacity of the speci
61 ation monitoring, to dose optimization to an MPA exposure target (as area under the concentration-tim
62 an quantify increases in flow in the AAo and MPA during strenuous exercise and is highly repeatable.
64 electrostatic interaction between DOTAP and MPA layer during the formation of DOPE-DOTAP-AuNP (DDA)
65 impacting marine protected areas (MPAs) and MPA networks, yet adaptation strategies are rarely incor
68 nts, referred to determine (131)I uptake and MPA for initial treatment after thyroidectomy (n = 39),
69 nces have revealed the medial preoptic area (MPA) as a key site for the regulation of torpor in mice.
72 formation (constituting a medial place area [MPA]), whereas anterior aspects process information that
73 creasingly impacting marine protected areas (MPAs) and MPA networks, yet adaptation strategies are ra
79 the global system of marine-protected areas (MPAs) represents individual species and the breadth of e
80 oal for establishing marine protected areas (MPAs) to conserve the ocean's biodiversity was set in 20
81 ility, large no-take marine protected areas (MPAs) with pelagic components are being implemented.
82 ncluding creation of marine protected areas (MPAs), reef restoration projects, and assisted evolution
91 (433 and 218 MPAs, respectively) to assess: MPA management processes; the effects of MPAs on fish po
92 In contrast to the original server-based MPA application, this newly developed tool no longer req
95 ber and coverage of MPAs are increasing, but MPA implementation lags in many human-dominated regions.
99 partly recover HCV replication inhibited by MPA; however, silencing their expression by siRNAs could
101 ath were reduced with CEE but not with CEE + MPA, and those for hypertension followed by death were i
102 trogens and medroxyprogesterone acetate (CEE+MPA) resulted in increased risk of coronary heart diseas
105 n the direction of increased CHD risk by CEE+MPA; the remaining 11 metabolites were not significantly
106 , for myocardial infarction, results for CEE+MPA were in the direction of risk elevation in WHI and i
107 initiation, associations of CEE alone or CEE+MPA with most clinical outcomes were highly concordant b
109 changed with randomized CEE and 52% with CEE+MPA (false discovery rate-adjusted P value<0.05) in mult
110 ch was high in the front of migrating cells, MPA density was low in the front and high in the back.
111 imulated peripheral blood mononuclear cells, MPA and dexamethasone, but not NET-A, upregulated (media
112 In contrast, with genital CD4+ T cells, MPA suppressed TAF inhibition of HIV infection and lower
114 s not completely characterized how to design MPAs under diverse ecological and economic conditions wh
115 ll as an important aspect of reserve design (MPA size) into a general model and determined their comb
116 es, in the context of managing and designing MPA networks, may ensure that conservation goals are ach
119 ons and progesterone were measured pre-dose (MPA only), 2, 4, 6, 8, 10 and 12 weeks after a single DM
131 f knowledge for adapting existing and future MPAs to climate change and synthesize case studies (n =
132 We also estimate that the current global MPA system secures only 1.7% of the Tree of Life for cor
133 strategically expanding the existing global MPA network to protect an additional 5% of the ocean cou
134 and at a 2-propanol flow rate of 160 muL/h, MPA demonstrated the greatest shift in mobility (1.58 cm
135 Five women (11.9%; 95% CI, 4.0-25.6%) had MPA <0.1 ng/mL at week 12; of these, one had MPA <0.1 ng
136 Five women [11.9% (95% CI 4.0-25.6%)] had MPA <0.1 ng/mL at week 12; of these, one had MPA <0.1 ng
139 g effectively and equitably managed, and how MPA management influences substantive outcomes remain un
140 s common in many coastal nations, we ask how MPAs can be designed specifically to improve fisheries y
141 on could induce cellular autophagy, however, MPA also exhibited its inhibitory effect on tunicamycin-
142 strongest predictors of conservation impact: MPAs with adequate staff capacity had ecological effects
144 rld examples of climate change adaptation in MPA planning derive from tropical reefs, highlighting th
145 12, significantly reduced the worm burden in MPA-treated mice undergoing hyperinfection with S. sterc
146 mortality resulting from small increases in MPA size, allowing us to bridge a critical gap between t
148 irectly perceptual and mnemonic responses in MPA and an anterior, connectivity-defined region (CON),
152 tration (target concentration intervention), MPA exposure is successfully controlled and clinical ben
153 tion strategies are rarely incorporated into MPA design and management plans according to the primary
154 ally relevant concentrations of 4.5-4.8 ng/L MPA, DDG and the mixture in eleuthero-embryos and at 43-
157 ed to increase, and the role of low-latitude MPAs as a sink for urchins changed significantly in cont
159 ng of the (methyl) methylphosphonic acid ((M)MPA) product to the polyanions, which ultimately inhibit
163 1.42 +/- 0.3 g/day and the individual median MPA trough concentration in the time period of anticipat
166 tion problems that arise from mismanagement, MPAs can also benefit fisheries beyond their borders.
167 The comparison between mTORi-CNI and MMF/MPA-CNI did not show differences in acute rejection, mor
172 Better graft function was observed using MMF/MPA-CNI than using mTORi + CNI, but this difference was
174 osphatidylcholine (p < 0.01 at 72 h; 100 muM MPA) which corresponded to the changes in lipid-metaboli
175 < 0.001 at 24 and 72 h; 5, 100, and 250 muM MPA) and upregulation of uridine and cytidine nucleotide
177 ) in KTR on sirolimus (SRL) + mycophenolate (MPA) or SRL + tacrolimus (Tac), relative to the control-
181 vity suggest the potential use of this novel MPA-Candida assay in clinical diagnosis and in the contr
184 leading to sub-therapeutic concentrations of MPA in 12% of women, suggesting that more frequent dosin
185 leading to subtherapeutic concentrations of MPA in 12% of women, suggesting that more frequent dosin
187 food provisioning can be a central driver of MPA design, offering a pathway to strategically conserve
188 ing path nullifying the insulating effect of MPA and also act as a proper immobilization platform for
190 gesterone receptor, the preventive effect of MPA was absent in human papillomavirus transgenic mice i
191 own, South Africa, to evaluate the effect of MPA, NET-A, and dexamethasone on Mtb containment in mono
194 We demonstrated that the incorporation of MPA functionalized gold nanoparticles (AuNPMPA) as an el
195 omass were only correlated with the level of MPA enforcement; fish density was higher in older, bette
197 n in T cells was observed in the presence of MPA, which also broadly upregulated chemokine production
199 Cross-reference with previous studies of MPA-associated protein changes widely corroborated these
202 estimates the conservation effectiveness of MPAs for five species of coral reef-associated sharks (T
204 ss: MPA management processes; the effects of MPAs on fish populations; and relationships between mana
208 ly to change connectivity among a network of MPAs spanning over 1000 km of coastline off the coast of
213 r kelp, poleward connectivity among pairs of MPAs tended to increase in the future, whereas equatorwa
215 nge in predicted connectivity among pairs of MPAs within the network did not change significantly ove
216 y patterns across populations in a series of MPAs in the common yellowhead Jawfish, Opistognathus aur
217 ps the greatest challenge to expanded use of MPAs is the perceived trade-off between protection and f
220 targeted fish species also increased outside MPAs, although only 27% as rapidly as in the protected a
221 ing and support the continuation of paternal MPA treatment before, during, and after conception.
222 ecovery efficiencies for methyl phosphonate (MPA), nerve agent degradate, and ethylhydrogen dimethylp
226 opausal women, hormone therapy with CEE plus MPA for a median of 5.6 years or with CEE alone for a me
227 ty, whereas prior randomized use of CEE plus MPA, compared with placebo, among women who had an intac
228 in the overall pooled cohort; with CEE plus MPA, the HR was 1.02 (95% CI, 0.96-1.08); and with CEE a
230 ions and progesterone were measured predose (MPA only) and 2, 4, 6, 8, 10, and 12 weeks after a singl
233 eas selective ablation of estrogen-sensitive MPA neurons demonstrated that these neurons are required
235 ndings suggest a role for estrogen-sensitive MPA neurons in directing the thermoregulatory and metabo
236 Selectively activating estrogen-sensitive MPA neurons was sufficient to drive a coordinated depres
238 alue and/or low harvesting cost, while small MPAs or no closure are best for species lightly harveste
240 patient death and graft loss, although SRL + MPA was associated with a lower risk for posttransplant
242 erostatus to any of the above viruses, SRL + MPA or SRL + Tac was not associated with a different mal
243 more data are needed to evaluate sufficient MPA sizes for protecting populations of species with var
247 would need to be enforced as strict no-take MPAs and up to 5 times larger to expect protection of th
249 e presently under-represented within no-take MPAs that aim to effectively protect marine predators, s
256 d and genital CD4+ T cells and suggests that MPA may decrease ARV protection in individuals who use A
263 trate that estrogen-sensitive neurons in the MPA can coordinate hypothermia and hypometabolism in mic
266 nic pressures, they also include much of the MPA network that may provide stepping-stone protection f
267 e of the bilayer and semi circled DDA on the MPA and cysteamine layers were confirmed by the increase
268 nce of an array like semi circled DDA on the MPA and well separated DDA vesicles on the MUDA with var
269 PEG functionalized gold nanoparticles on the MPA surface provided good electron conducting path nulli
272 conventional methods, demonstrating that the MPA is an important tool for cellular receptor discovery
274 or the behavioral response of fishers to the MPA; this approach is distinct from much of the literatu
275 on blood measurements alone is comparable to MPA obtained with combined body counting and blood sampl
281 the responses of zebrafish (Danio rerio) to MPA, DDG, and their binary mixtures at measured concentr
284 val revealed better results for mTORi versus MPA in terms of biopsy-proven acute rejection (hazard ra
285 val revealed better results for mTORi versus MPA in terms of biopsy-proven acute rejection [Hazard Ra
286 activated during scene construction than was MPA, whereas MPA was more perceptually responsive than C
289 ur results offer strategic guidance on where MPAs should be placed to support the CBD's overall goal
291 Here, we investigated the mechanism whereby MPA inhibits RNA polymerase III (Pol III) activity, in b
297 ociate from tRNA genes in yeast treated with MPA, even though there is a sharp decrease in the levels
298 local abundances and fishing pressure, with MPAs required to be 1.6-2.6 times larger to protect the
299 to fishing mortality of sharks found within MPAs as they move outside to adjacent fishing grounds.